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The map label for this gene is sstT

Identifier: 119944278

GI number: 119944278

Start: 639893

End: 641170

Strand: Reverse

Name: sstT

Synonym: Ping_0504

Alternate gene names: 119944278

Gene position: 641170-639893 (Counterclockwise)

Preceding gene: 119944281

Following gene: 119944275

Centisome position: 14.06

GC content: 42.8

Gene sequence:

>1278_bases
ATGACCCCAACCCCCACTCTCATTCAACGATTTTTAAACGGAAGTTTAGTTTTACAAATAGTAATAGGCATTGTAGCCGG
TTTAATACTGGCAAGCTTTTCACCAACAAGCGCCTTGTCAGTCTCCTTTTTAGGCAGTTTATTCGTCAGTGCTTTAAAAG
CTGTCGCACCCATTTTAGTTTTTGTGTTAGTTGCCTCTTCGATTGCGAATCAACAAAAAGAAACCCGTACCAATCTTAAA
CCTATTATTAAGCTTTATTTGCTTGGCACGCTATTCGCAGCATCTACCGCTGTTATGGTGAGTTATTTTTTCCCTACCAC
TTTAGTACTGGTTGCAACCGATATTCAAGCAACGCCGCCAAATGGGATCCTTGAAGTATTAAATACCCTTTTATTTAAAA
TCGTTGATAACCCGGTAAATGCATTAGTGAGCGGCAATTTTATTGGTATTTTAGCATGGGCGGCAGGTTTAGGCTTTGCT
CTGCAACGTGCCAACCAAAGTACCAAACAGGCATTACATGATATCTCCAATGCTGTGACCCGCATTGTTCATTTAGTGAT
ACGTTTTGCACCTCTTGGTATTTTTGGCTTAGTCGCAGGGACTATTGCCGAAACAGGCTTTGACGCGCTTTTCGGCTACA
CCCATTTATTAGCGGTATTACTTGGCTGTATGATCTTAATTGCCCTGGTGATTAACCCAATTATTGTCTATGGAAAAACG
AAAAAAAATCCATACCCGTTAATTTTCAGATGTTTACGTGAATCTGGTGTCACGGCCTTCTTTACTCGCAGTTCAGCTGC
CAATATCCCGGTGAACATGGCGTTGTGTGAGAAATTAGAGCTGCACAAAGATACTTACTCTGTATCAATTCCGCTTGGTG
CAACTATCAATATGGCGGGTGCTTCAATCACCATCACAGTATTGACCTTAGCGGCAGTGCATACCTTGGGCATTGAATTT
GATATTGCCACGGCTATTTTATTAAGTGTGGTGGCTGCTGTTTCGGCTTGCGGGGCATCCGGTGTTGCAGGCGGTTCTTT
ATTATTAATTCCACTTGCCTGTGGATTATTTGGTGTACCCAATGAAGTCGCAATGCAGGTGGTCGCAATAGGTTTCATTA
TTGGTGTTGTTCAAGATTCAGCGGAAACTGCATTAAATAGCTCAACGGATGTGATCTTTACAGCAGCGGCTTGTTACGCA
GCAGAAGAATTACCAGCAGCGGATACGATTGAAACGCTGGAAACGCTGGAAACGCTGGAAACGACGGCAAAAGCATAA

Upstream 100 bases:

>100_bases
ATAATACGTGCCAATTACCCCTATAAAGGTGATTTCCATATACCCGCAACTAGCTGGATTTATTGACCACGAATCCCATA
ATATAAAACAGGTTTAAGAT

Downstream 100 bases:

>100_bases
CAGTAAAAGATCAAAGCCGAGTGTAAAAACTCGGCTTTGATCTTATCTAATACTGATTATTTAGACTAAAAAAAGGGTGA
TCTAAATTAAAAGGTAAAAA

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MTPTPTLIQRFLNGSLVLQIVIGIVAGLILASFSPTSALSVSFLGSLFVSALKAVAPILVFVLVASSIANQQKETRTNLK
PIIKLYLLGTLFAASTAVMVSYFFPTTLVLVATDIQATPPNGILEVLNTLLFKIVDNPVNALVSGNFIGILAWAAGLGFA
LQRANQSTKQALHDISNAVTRIVHLVIRFAPLGIFGLVAGTIAETGFDALFGYTHLLAVLLGCMILIALVINPIIVYGKT
KKNPYPLIFRCLRESGVTAFFTRSSAANIPVNMALCEKLELHKDTYSVSIPLGATINMAGASITITVLTLAAVHTLGIEF
DIATAILLSVVAAVSACGASGVAGGSLLLIPLACGLFGVPNEVAMQVVAIGFIIGVVQDSAETALNSSTDVIFTAAACYA
AEELPAADTIETLETLETLETTAKA

Sequences:

>Translated_425_residues
MTPTPTLIQRFLNGSLVLQIVIGIVAGLILASFSPTSALSVSFLGSLFVSALKAVAPILVFVLVASSIANQQKETRTNLK
PIIKLYLLGTLFAASTAVMVSYFFPTTLVLVATDIQATPPNGILEVLNTLLFKIVDNPVNALVSGNFIGILAWAAGLGFA
LQRANQSTKQALHDISNAVTRIVHLVIRFAPLGIFGLVAGTIAETGFDALFGYTHLLAVLLGCMILIALVINPIIVYGKT
KKNPYPLIFRCLRESGVTAFFTRSSAANIPVNMALCEKLELHKDTYSVSIPLGATINMAGASITITVLTLAAVHTLGIEF
DIATAILLSVVAAVSACGASGVAGGSLLLIPLACGLFGVPNEVAMQVVAIGFIIGVVQDSAETALNSSTDVIFTAAACYA
AEELPAADTIETLETLETLETTAKA
>Mature_424_residues
TPTPTLIQRFLNGSLVLQIVIGIVAGLILASFSPTSALSVSFLGSLFVSALKAVAPILVFVLVASSIANQQKETRTNLKP
IIKLYLLGTLFAASTAVMVSYFFPTTLVLVATDIQATPPNGILEVLNTLLFKIVDNPVNALVSGNFIGILAWAAGLGFAL
QRANQSTKQALHDISNAVTRIVHLVIRFAPLGIFGLVAGTIAETGFDALFGYTHLLAVLLGCMILIALVINPIIVYGKTK
KNPYPLIFRCLRESGVTAFFTRSSAANIPVNMALCEKLELHKDTYSVSIPLGATINMAGASITITVLTLAAVHTLGIEFD
IATAILLSVVAAVSACGASGVAGGSLLLIPLACGLFGVPNEVAMQVVAIGFIIGVVQDSAETALNSSTDVIFTAAACYAA
EELPAADTIETLETLETLETTAKA

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family

Homologues:

Organism=Homo sapiens, GI169790839, Length=266, Percent_Identity=25.9398496240602, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4827012, Length=290, Percent_Identity=25.8620689655172, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI223468566, Length=266, Percent_Identity=27.0676691729323, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI223468564, Length=254, Percent_Identity=26.3779527559055, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI66773030, Length=270, Percent_Identity=25.5555555555556, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI5032093, Length=263, Percent_Identity=26.9961977186312, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI194239697, Length=445, Percent_Identity=24.2696629213483, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI21314632, Length=337, Percent_Identity=25.2225519287834, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI262359914, Length=238, Percent_Identity=27.7310924369748, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI40254478, Length=341, Percent_Identity=24.3401759530792, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1789473, Length=400, Percent_Identity=65, Blast_Score=510, Evalue=1e-146,
Organism=Escherichia coli, GI1790514, Length=405, Percent_Identity=25.4320987654321, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789947, Length=355, Percent_Identity=25.3521126760563, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71983106, Length=274, Percent_Identity=25.5474452554745, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71983099, Length=274, Percent_Identity=25.5474452554745, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193206505, Length=423, Percent_Identity=24.822695035461, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17537407, Length=426, Percent_Identity=23.4741784037559, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71996953, Length=269, Percent_Identity=24.5353159851301, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24583025, Length=284, Percent_Identity=25.3521126760563, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI17137668, Length=284, Percent_Identity=25.3521126760563, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24583023, Length=284, Percent_Identity=25.3521126760563, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SSTT_PSYIN (A1SS94)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_941958.1
- ProteinModelPortal:   A1SS94
- SMR:   A1SS94
- STRING:   A1SS94
- GeneID:   4623410
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0504
- eggNOG:   COG3633
- HOGENOM:   HBG289387
- OMA:   THIRPIL
- PhylomeDB:   A1SS94
- ProtClustDB:   PRK13628
- BioCyc:   PING357804:PING_0504-MONOMER
- HAMAP:   MF_01582
- InterPro:   IPR001991
- InterPro:   IPR023025
- PANTHER:   PTHR11958
- PRINTS:   PR00173

Pfam domain/function: PF00375 SDF

EC number: NA

Molecular weight: Translated: 44346; Mature: 44215

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1; PS00714 NA_DICARBOXYL_SYMP_2; PS00435 PEROXIDASE_1 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15620138)-; HASH(0x16546294)-; HASH(0x16546474)-; HASH(0x165463e4)-; HASH(0x1625d4c8)-; HASH(0x16532234)-; HASH(0x165241a4)-; HASH(0x160c564c)-; HASH(0x15ffd880)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCH
>Mature Secondary Structure 
TPTPTLIQRFLNGSLVLQIVIGIVAGLILASFSPTSALSVSFLGSLFVSALKAVAPILV
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FVLVASSIANQQKETRTNLKPIIKLYLLGTLFAASTAVMVSYFFPTTLVLVATDIQATPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCC
NGILEVLNTLLFKIVDNPVNALVSGNFIGILAWAAGLGFALQRANQSTKQALHDISNAVT
HHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RIVHLVIRFAPLGIFGLVAGTIAETGFDALFGYTHLLAVLLGCMILIALVINPIIVYGKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
KKNPYPLIFRCLRESGVTAFFTRSSAANIPVNMALCEKLELHKDTYSVSIPLGATINMAG
CCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEECC
ASITITVLTLAAVHTLGIEFDIATAILLSVVAAVSACGASGVAGGSLLLIPLACGLFGVP
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCC
NEVAMQVVAIGFIIGVVQDSAETALNSSTDVIFTAAACYAAEELPAADTIETLETLETLE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TTAKA
HHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA