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The map label for this gene is glnS

Identifier: 119944267

GI number: 119944267

Start: 625231

End: 626892

Strand: Direct

Name: glnS

Synonym: Ping_0492

Alternate gene names: 119944267

Gene position: 625231-626892 (Clockwise)

Preceding gene: 119944266

Following gene: 119944268

Centisome position: 13.71

GC content: 41.58

Gene sequence:

>1662_bases
ATGACTCAGGTTGATACTGCGCCAAGCAATTTTATTCGTAACATCATCGATTCGGATCTACAAAGTGGTAAGCATCAGGT
GATACATACACGCTTTCCGCCGGAACCGAATGGTTATTTGCATATAGGTCATGCTAAATCTATCTGTTTAAATTTTGGAC
TTGCAGAAGACTACCCCAATGCACTTTGCAATCTGCGTTTTGATGATACTAATCCAGTAAAAGAAGATGCGGATTATGTT
GCCGCTATTGAAAAGGATGTGCGTTGGTTGGGGTTTAAATGGGCGGGTGATATACATTATTCATCTGACTATTTTGAACA
GTTGTATGACTTTGCCATTGAGTTAATTAAAAAAGATAAAGCTTATGTTTGTGCTCTCGACGCACAACAAACTCGAGAAT
ATCGAGGTTCGTTAATGACAGTGGGTAAAGACAGCCCCTTTAGAAATCGCCCTATTTCAGAAAGTTTAGATCTTTTTGCG
CGTATGCGTGCGGGTGAGTTTGCGGAAGGCTCGATGATGCTGCGGGCAAAAATTGATATGGCGTCACCAAATATGAAAAT
GCGTGATCCGGTTCTTTATCGCATTCGTTTTGCGCATCATCATCAAACGGGTGATAAATGGTGTATCTATCCAATGTACG
ATTTTACCCATTGTATTTCAGATGCGCTTGAAGGCATAACCCATAGCCTGTGTACACTTGAATTTGAAGATCACCGCCCT
TTATATGATTGGGTATTAGCCAATATCAGTATTGCCTGTAAACCACGTCAAATTGAGTTTTCCCGTCTTAATTTACAATA
TACTTTAACCTCTAAACGTAAACTACATACGTTAATTGAAGAGAAGATTATAAGTGCTTGGGATGATCCGCGGATGCCGA
CTATTTCCGGTATGCGCCGCCGTGGTTATCCGGCCGCCTCTATTCGTGAATTTTGTAAACGTATTGGTGTGACTAAACAG
GAAAATACCGTTGAACTGGCCTCGTTAGAAGCTTGTGTTCGTGAAAATCTTGAAGCTAATGCGCCTCGCGCAATGGCTGT
GATTGATCCTGTTAAAGTGATTATTAGCAATTATGACGAAAATAAAACAGAAAAATTAATCGCGGCTATACACCCTAAAG
ATGAAAGCATGGGGACAAGAACAGTCACTTTCTCACGAGAAATTTTTATTGACCGTGCTGATTTTAGAGAAGAGGCGAAT
AAAAAATATAAACGTTTAGTCTTGGGTAAAGAAGTGCGTTTACGTAATGCTTATGTGATTAAAGCTGATCAGGTCATTAA
GAATGATGCCGGCGAAATTACTGAAATTCACTGCTCTTACGATCCTGAAACGCTGGGCAACAATCCAACGGACGGGCGTA
AAGTGAAAGGCGTGATCCATTGGGTTAGTGCGGTTGAAAACCAAGCAGCAGAGTTTCGAATCTATGAGCCTTTGTTTCTG
GTTGAAAATCCTGCTGCCGCAGAAAATATCGACGAAGTACTCAATCCAAACGCTTTAGTGATAAAACACGGTTTTGTGGA
GTCAGGTCTTAGTGATGCGCTAGCAGAAAAAGCTTATCAATTCGAGCGTGAAGGTTACTTCTGTGCCGATAATAAGGATT
CATCACCCGAACGGCTGGTTTTTAACCGTACCGTTGCGTTGCGTGACTCTTGGGGCGGATAG

Upstream 100 bases:

>100_bases
TGTATTGTTGCTCTTTTGCTGCTTATTTCCCTTGAGGTTAGCCTTAGAATATAAGATGATTAATCCTATTTTTTGATTTA
TATTTATTTAGAGGTAAGCA

Downstream 100 bases:

>100_bases
CACCTTTCATACCTCAATATGCCAATTGCGCATCTTGAGGTAGATTAAATGCTGCTGCATCTCTTTTGTTATGCGCAGCA
TTGTATTTTCTAAAGCGCTT

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MTQVDTAPSNFIRNIIDSDLQSGKHQVIHTRFPPEPNGYLHIGHAKSICLNFGLAEDYPNALCNLRFDDTNPVKEDADYV
AAIEKDVRWLGFKWAGDIHYSSDYFEQLYDFAIELIKKDKAYVCALDAQQTREYRGSLMTVGKDSPFRNRPISESLDLFA
RMRAGEFAEGSMMLRAKIDMASPNMKMRDPVLYRIRFAHHHQTGDKWCIYPMYDFTHCISDALEGITHSLCTLEFEDHRP
LYDWVLANISIACKPRQIEFSRLNLQYTLTSKRKLHTLIEEKIISAWDDPRMPTISGMRRRGYPAASIREFCKRIGVTKQ
ENTVELASLEACVRENLEANAPRAMAVIDPVKVIISNYDENKTEKLIAAIHPKDESMGTRTVTFSREIFIDRADFREEAN
KKYKRLVLGKEVRLRNAYVIKADQVIKNDAGEITEIHCSYDPETLGNNPTDGRKVKGVIHWVSAVENQAAEFRIYEPLFL
VENPAAAENIDEVLNPNALVIKHGFVESGLSDALAEKAYQFEREGYFCADNKDSSPERLVFNRTVALRDSWGG

Sequences:

>Translated_553_residues
MTQVDTAPSNFIRNIIDSDLQSGKHQVIHTRFPPEPNGYLHIGHAKSICLNFGLAEDYPNALCNLRFDDTNPVKEDADYV
AAIEKDVRWLGFKWAGDIHYSSDYFEQLYDFAIELIKKDKAYVCALDAQQTREYRGSLMTVGKDSPFRNRPISESLDLFA
RMRAGEFAEGSMMLRAKIDMASPNMKMRDPVLYRIRFAHHHQTGDKWCIYPMYDFTHCISDALEGITHSLCTLEFEDHRP
LYDWVLANISIACKPRQIEFSRLNLQYTLTSKRKLHTLIEEKIISAWDDPRMPTISGMRRRGYPAASIREFCKRIGVTKQ
ENTVELASLEACVRENLEANAPRAMAVIDPVKVIISNYDENKTEKLIAAIHPKDESMGTRTVTFSREIFIDRADFREEAN
KKYKRLVLGKEVRLRNAYVIKADQVIKNDAGEITEIHCSYDPETLGNNPTDGRKVKGVIHWVSAVENQAAEFRIYEPLFL
VENPAAAENIDEVLNPNALVIKHGFVESGLSDALAEKAYQFEREGYFCADNKDSSPERLVFNRTVALRDSWGG
>Mature_552_residues
TQVDTAPSNFIRNIIDSDLQSGKHQVIHTRFPPEPNGYLHIGHAKSICLNFGLAEDYPNALCNLRFDDTNPVKEDADYVA
AIEKDVRWLGFKWAGDIHYSSDYFEQLYDFAIELIKKDKAYVCALDAQQTREYRGSLMTVGKDSPFRNRPISESLDLFAR
MRAGEFAEGSMMLRAKIDMASPNMKMRDPVLYRIRFAHHHQTGDKWCIYPMYDFTHCISDALEGITHSLCTLEFEDHRPL
YDWVLANISIACKPRQIEFSRLNLQYTLTSKRKLHTLIEEKIISAWDDPRMPTISGMRRRGYPAASIREFCKRIGVTKQE
NTVELASLEACVRENLEANAPRAMAVIDPVKVIISNYDENKTEKLIAAIHPKDESMGTRTVTFSREIFIDRADFREEANK
KYKRLVLGKEVRLRNAYVIKADQVIKNDAGEITEIHCSYDPETLGNNPTDGRKVKGVIHWVSAVENQAAEFRIYEPLFLV
ENPAAAENIDEVLNPNALVIKHGFVESGLSDALAEKAYQFEREGYFCADNKDSSPERLVFNRTVALRDSWGG

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI4826960, Length=548, Percent_Identity=44.5255474452555, Blast_Score=431, Evalue=1e-120,
Organism=Homo sapiens, GI62241042, Length=510, Percent_Identity=33.5294117647059, Blast_Score=251, Evalue=1e-66,
Organism=Escherichia coli, GI1786895, Length=552, Percent_Identity=67.3913043478261, Blast_Score=790, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17543332, Length=530, Percent_Identity=40.188679245283, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17511007, Length=449, Percent_Identity=32.739420935412, Blast_Score=214, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6324742, Length=563, Percent_Identity=38.5435168738899, Blast_Score=375, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6321192, Length=530, Percent_Identity=33.2075471698113, Blast_Score=272, Evalue=9e-74,
Organism=Drosophila melanogaster, GI17864488, Length=534, Percent_Identity=43.0711610486891, Blast_Score=429, Evalue=1e-120,
Organism=Drosophila melanogaster, GI24649466, Length=464, Percent_Identity=34.051724137931, Blast_Score=238, Evalue=8e-63,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYQ_PSYIN (A1SS83)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_941947.1
- ProteinModelPortal:   A1SS83
- SMR:   A1SS83
- STRING:   A1SS83
- GeneID:   4626872
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0492
- eggNOG:   COG0008
- HOGENOM:   HBG334108
- OMA:   RMPTIAG
- PhylomeDB:   A1SS83
- ProtClustDB:   PRK05347
- BioCyc:   PING357804:PING_0492-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00126
- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729
- Gene3D:   G3DSA:1.10.1160.10
- Gene3D:   G3DSA:2.40.240.10
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10119:SF3
- PANTHER:   PTHR10119
- PRINTS:   PR00987
- TIGRFAMs:   TIGR00440

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C; SSF50715 Ribosomal_L25rel

EC number: =6.1.1.18

Molecular weight: Translated: 63197; Mature: 63066

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 272-272

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQVDTAPSNFIRNIIDSDLQSGKHQVIHTRFPPEPNGYLHIGHAKSICLNFGLAEDYPN
CCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEECCHHEEHEECCCCCCCCC
ALCNLRFDDTNPVKEDADYVAAIEKDVRWLGFKWAGDIHYSSDYFEQLYDFAIELIKKDK
HHEEEEECCCCCCHHHHHHHHHHHHCHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCC
AYVCALDAQQTREYRGSLMTVGKDSPFRNRPISESLDLFARMRAGEFAEGSMMLRAKIDM
CEEEEECHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEC
ASPNMKMRDPVLYRIRFAHHHQTGDKWCIYPMYDFTHCISDALEGITHSLCTLEFEDHRP
CCCCCCCCCCEEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCCC
LYDWVLANISIACKPRQIEFSRLNLQYTLTSKRKLHTLIEEKIISAWDDPRMPTISGMRR
HHHHHHHCCEEEECCCEEEEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
RGYPAASIREFCKRIGVTKQENTVELASLEACVRENLEANAPRAMAVIDPVKVIISNYDE
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCC
NKTEKLIAAIHPKDESMGTRTVTFSREIFIDRADFREEANKKYKRLVLGKEVRLRNAYVI
CHHHEEEEEECCCCCCCCCEEEEEEHEEEEEHHHHHHHHHHHHHHHHHCCCEEECCEEEE
KADQVIKNDAGEITEIHCSYDPETLGNNPTDGRKVKGVIHWVSAVENQAAEFRIYEPLFL
EHHHHHHCCCCCEEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCEEE
VENPAAAENIDEVLNPNALVIKHGFVESGLSDALAEKAYQFEREGYFCADNKDSSPERLV
ECCCCHHHHHHHHHCCCEEEEECCCHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCEEE
FNRTVALRDSWGG
EEEEEEEECCCCC
>Mature Secondary Structure 
TQVDTAPSNFIRNIIDSDLQSGKHQVIHTRFPPEPNGYLHIGHAKSICLNFGLAEDYPN
CCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEECCHHEEHEECCCCCCCCC
ALCNLRFDDTNPVKEDADYVAAIEKDVRWLGFKWAGDIHYSSDYFEQLYDFAIELIKKDK
HHEEEEECCCCCCHHHHHHHHHHHHCHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCC
AYVCALDAQQTREYRGSLMTVGKDSPFRNRPISESLDLFARMRAGEFAEGSMMLRAKIDM
CEEEEECHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEC
ASPNMKMRDPVLYRIRFAHHHQTGDKWCIYPMYDFTHCISDALEGITHSLCTLEFEDHRP
CCCCCCCCCCEEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCCC
LYDWVLANISIACKPRQIEFSRLNLQYTLTSKRKLHTLIEEKIISAWDDPRMPTISGMRR
HHHHHHHCCEEEECCCEEEEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
RGYPAASIREFCKRIGVTKQENTVELASLEACVRENLEANAPRAMAVIDPVKVIISNYDE
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCC
NKTEKLIAAIHPKDESMGTRTVTFSREIFIDRADFREEANKKYKRLVLGKEVRLRNAYVI
CHHHEEEEEECCCCCCCCCEEEEEEHEEEEEHHHHHHHHHHHHHHHHHCCCEEECCEEEE
KADQVIKNDAGEITEIHCSYDPETLGNNPTDGRKVKGVIHWVSAVENQAAEFRIYEPLFL
EHHHHHHCCCCCEEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCEEE
VENPAAAENIDEVLNPNALVIKHGFVESGLSDALAEKAYQFEREGYFCADNKDSSPERLV
ECCCCHHHHHHHHHCCCEEEEECCCHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCEEE
FNRTVALRDSWGG
EEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA