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The map label for this gene is nagB

Identifier: 119944265

GI number: 119944265

Start: 622256

End: 623056

Strand: Reverse

Name: nagB

Synonym: Ping_0490

Alternate gene names: 119944265

Gene position: 623056-622256 (Counterclockwise)

Preceding gene: 119944269

Following gene: 119944264

Centisome position: 13.66

GC content: 39.58

Gene sequence:

>801_bases
ATGCGTTTAATTCCTCTTGAAACAACCTCTGATGTCGCCTTCTGGTCTGCTCGCTACATTAGCGATGCAATTAATAAATA
TTCACCCACCAAAGAACGACCTTTTGTATTGGGTTTACCAACCGGCGGCACGCCACTGGAAACTTATAAACGTCTTATAG
CACTTTATAATAAAGGCGAAGTAAGTTTTGAAAATGTCGTTACCTTTAATATGGATGAATATGTTGGTCTCGAACAGGAA
CATCCTCAAAGCTATTATCGCTTTATGCATCAGAATTTTTTCAGCCAGATTGATATCCAAATAGAAAATACCCATCTACT
TAACGGGCTTGCAGATGATCTGGAAGCCGAATGCCTACGTTATGAGAAAAAGATCAAGTCTTACGGAAAAATTAATTTAT
TTATCGGTGGCGTTGGTGCAGATGGCCATATCGCCTTTAATGAACCGGCATCCTCATTGGCTTCGCGTACACGCGTTAAA
ACATTAGCCTCAAATACACGAAGAGCTAACTCACGTTTTTTCAACAACGATATTAACCAGGTGCCTAAATTGGCATTGAC
CATTGGTGTTGGCACTTTATTAGAGGCCGCAGAAATATTAATTCTGGTAACTGGTCACCATAAAGCACAGGCACTTGAAG
CCGCTATACAAGGTAATGTAAACCACCTTTGGACCGTTACTGCATTACAACTTCATCCAAAAACGATCATTGCCTGTGAT
GCAGCATCGACAATGGAACTGAAAGTTAAAACATTAAAGTACTTCTCTGAATTAGAAAGCGACAATATTGGCTATTTATA
A

Upstream 100 bases:

>100_bases
CTGTTAAGCATCTTTTTCAGGCATTTATATGGCAATAAAGCGCGACTTAATTTACGCTACGTATTAACTACACAAGCAAT
CTTAATATACGGAGTAAAAA

Downstream 100 bases:

>100_bases
ACGTCATTAATCACAGCCGGTATTTAATTCGAGTAAAATTAATGGGGGAAAGCTTCTAATAAGCAATTTTCAATTGTAAA
ATAAAAAAGCTTTCTTTTTA

Product: glucosamine-6-phosphate deaminase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MRLIPLETTSDVAFWSARYISDAINKYSPTKERPFVLGLPTGGTPLETYKRLIALYNKGEVSFENVVTFNMDEYVGLEQE
HPQSYYRFMHQNFFSQIDIQIENTHLLNGLADDLEAECLRYEKKIKSYGKINLFIGGVGADGHIAFNEPASSLASRTRVK
TLASNTRRANSRFFNNDINQVPKLALTIGVGTLLEAAEILILVTGHHKAQALEAAIQGNVNHLWTVTALQLHPKTIIACD
AASTMELKVKTLKYFSELESDNIGYL

Sequences:

>Translated_266_residues
MRLIPLETTSDVAFWSARYISDAINKYSPTKERPFVLGLPTGGTPLETYKRLIALYNKGEVSFENVVTFNMDEYVGLEQE
HPQSYYRFMHQNFFSQIDIQIENTHLLNGLADDLEAECLRYEKKIKSYGKINLFIGGVGADGHIAFNEPASSLASRTRVK
TLASNTRRANSRFFNNDINQVPKLALTIGVGTLLEAAEILILVTGHHKAQALEAAIQGNVNHLWTVTALQLHPKTIIACD
AASTMELKVKTLKYFSELESDNIGYL
>Mature_266_residues
MRLIPLETTSDVAFWSARYISDAINKYSPTKERPFVLGLPTGGTPLETYKRLIALYNKGEVSFENVVTFNMDEYVGLEQE
HPQSYYRFMHQNFFSQIDIQIENTHLLNGLADDLEAECLRYEKKIKSYGKINLFIGGVGADGHIAFNEPASSLASRTRVK
TLASNTRRANSRFFNNDINQVPKLALTIGVGTLLEAAEILILVTGHHKAQALEAAIQGNVNHLWTVTALQLHPKTIIACD
AASTMELKVKTLKYFSELESDNIGYL

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily

Homologues:

Organism=Homo sapiens, GI13027378, Length=258, Percent_Identity=58.1395348837209, Blast_Score=323, Evalue=1e-88,
Organism=Homo sapiens, GI19923881, Length=258, Percent_Identity=55.0387596899225, Blast_Score=309, Evalue=1e-84,
Organism=Escherichia coli, GI1786893, Length=263, Percent_Identity=67.680608365019, Blast_Score=393, Evalue=1e-111,
Organism=Escherichia coli, GI1789530, Length=232, Percent_Identity=26.2931034482759, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI48994958, Length=239, Percent_Identity=26.3598326359833, Blast_Score=71, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17554876, Length=258, Percent_Identity=53.8759689922481, Blast_Score=284, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24581960, Length=261, Percent_Identity=56.3218390804598, Blast_Score=321, Evalue=3e-88,
Organism=Drosophila melanogaster, GI19920764, Length=261, Percent_Identity=56.3218390804598, Blast_Score=321, Evalue=3e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NAGB_PSYIN (A1SS81)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_941945.1
- ProteinModelPortal:   A1SS81
- SMR:   A1SS81
- STRING:   A1SS81
- GeneID:   4626870
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0490
- eggNOG:   COG0363
- HOGENOM:   HBG725991
- OMA:   HLSITMG
- PhylomeDB:   A1SS81
- ProtClustDB:   PRK00443
- BioCyc:   PING357804:PING_0490-MONOMER
- HAMAP:   MF_01241
- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321
- PANTHER:   PTHR11280
- TIGRFAMs:   TIGR00502

Pfam domain/function: PF01182 Glucosamine_iso

EC number: =3.5.99.6

Molecular weight: Translated: 29786; Mature: 29786

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: ACT_SITE 72-72 ACT_SITE 141-141 ACT_SITE 143-143 ACT_SITE 148-148

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIPLETTSDVAFWSARYISDAINKYSPTKERPFVLGLPTGGTPLETYKRLIALYNKGE
CEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCC
VSFENVVTFNMDEYVGLEQEHPQSYYRFMHQNFFSQIDIQIENTHLLNGLADDLEAECLR
EEEEEEEEECHHHHCCCCCCCHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHH
YEKKIKSYGKINLFIGGVGADGHIAFNEPASSLASRTRVKTLASNTRRANSRFFNNDINQ
HHHHHHCCCEEEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHCCHHHCCHHHCCCHHH
VPKLALTIGVGTLLEAAEILILVTGHHKAQALEAAIQGNVNHLWTVTALQLHPKTIIACD
HHHEEEEHHHHHHHHHCEEEEEEECCCHHHHHHHHHCCCCCEEEEEEEEEECCCEEEEEC
AASTMELKVKTLKYFSELESDNIGYL
CCCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRLIPLETTSDVAFWSARYISDAINKYSPTKERPFVLGLPTGGTPLETYKRLIALYNKGE
CEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCC
VSFENVVTFNMDEYVGLEQEHPQSYYRFMHQNFFSQIDIQIENTHLLNGLADDLEAECLR
EEEEEEEEECHHHHCCCCCCCHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHH
YEKKIKSYGKINLFIGGVGADGHIAFNEPASSLASRTRVKTLASNTRRANSRFFNNDINQ
HHHHHHCCCEEEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHCCHHHCCHHHCCCHHH
VPKLALTIGVGTLLEAAEILILVTGHHKAQALEAAIQGNVNHLWTVTALQLHPKTIIACD
HHHEEEEHHHHHHHHHCEEEEEEECCCHHHHHHHHHCCCCCEEEEEEEEEECCCEEEEEC
AASTMELKVKTLKYFSELESDNIGYL
CCCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA