Click here to switch to the map view.

The map label for this gene is dnaQ [H]

Identifier: 119944269

GI number: 119944269

Start: 630552

End: 631271

Strand: Reverse

Name: dnaQ [H]

Synonym: Ping_0495

Alternate gene names: 119944269

Gene position: 631271-630552 (Counterclockwise)

Preceding gene: 119944271

Following gene: 119944265

Centisome position: 13.84

GC content: 41.94

Gene sequence:

>720_bases
ATGAACACAGAGAAAATGATACGACAGGTTGTGTTAGACACAGAGACAACGGGTATGAATAAAGGTGGCACAATTTATGT
CGGTCATCGGATCATCGAAATTGGTTGTGTTGAAGTTATTAATCGACGTTTAACCGGCCGCCATTTCCATGTTTATGTCA
AACCGGATCGTGAAATAGACCCCGAAGCGATAGCAGTTCATGGTATTACCGATGAATTTTTACACGATAAACCCGCATTT
AGCGACATTGCAGATGAATTCATAGAATTTATCAAAGGGGCCGAATTAGTTATCCATAACGCACCCTTTGACGTCGGTTT
TATGGATCAGGAGTTTCGTTTTTTAAATAAAAGAACAAAACCAACCGCTGAAATATCGACCATCACAGATACATTAGTCA
TGGCAAGAAAAATGTACCCCGGCAAACGCGCAAGCCTTGATGCTCTGTGCAGGGAACTGGGTATTGATAATAAGCACCGT
GTTCTGCATGGCGCTTTATTAGATGCGGAAATATTGGCGGATGTTTATCTGCTTATGACCGGAGGGCAAAAAAAACTTAA
CCTCTCAAGCTCTGGACAAAATGACACTAATACTGGAAAACGCGTAAGAAAAACACAATCGCCACTCACTATTATTAGCG
CCAGCGAAGATGAACAGCAAGCACATGAAAAACGCTTAGATCTCATTGAAAAGTCAGCCAGCTGCCTATGGCGGGAATAA

Upstream 100 bases:

>100_bases
ACTTCATTATGAAGTACCTGCATCTTGAGGTAATTTGGGTATTAGGTGGTAAACTATACGGCTAATATTCAAATTATTGA
AACTATTAATTGAGATCCGC

Downstream 100 bases:

>100_bases
GGATAGCCGGGTTGATATTGGAACGCGGTAATAAATCTAAAAATGAAATTTAAACAATGAACATTGTGATCAATGACCTT
ATGGCAAGCCTCAAAAAGCG

Product: DNA polymerase III, epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MNTEKMIRQVVLDTETTGMNKGGTIYVGHRIIEIGCVEVINRRLTGRHFHVYVKPDREIDPEAIAVHGITDEFLHDKPAF
SDIADEFIEFIKGAELVIHNAPFDVGFMDQEFRFLNKRTKPTAEISTITDTLVMARKMYPGKRASLDALCRELGIDNKHR
VLHGALLDAEILADVYLLMTGGQKKLNLSSSGQNDTNTGKRVRKTQSPLTIISASEDEQQAHEKRLDLIEKSASCLWRE

Sequences:

>Translated_239_residues
MNTEKMIRQVVLDTETTGMNKGGTIYVGHRIIEIGCVEVINRRLTGRHFHVYVKPDREIDPEAIAVHGITDEFLHDKPAF
SDIADEFIEFIKGAELVIHNAPFDVGFMDQEFRFLNKRTKPTAEISTITDTLVMARKMYPGKRASLDALCRELGIDNKHR
VLHGALLDAEILADVYLLMTGGQKKLNLSSSGQNDTNTGKRVRKTQSPLTIISASEDEQQAHEKRLDLIEKSASCLWRE
>Mature_239_residues
MNTEKMIRQVVLDTETTGMNKGGTIYVGHRIIEIGCVEVINRRLTGRHFHVYVKPDREIDPEAIAVHGITDEFLHDKPAF
SDIADEFIEFIKGAELVIHNAPFDVGFMDQEFRFLNKRTKPTAEISTITDTLVMARKMYPGKRASLDALCRELGIDNKHR
VLHGALLDAEILADVYLLMTGGQKKLNLSSSGQNDTNTGKRVRKTQSPLTIISASEDEQQAHEKRLDLIEKSASCLWRE

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=238, Percent_Identity=57.9831932773109, Blast_Score=293, Evalue=8e-81,
Organism=Escherichia coli, GI1788149, Length=173, Percent_Identity=31.7919075144509, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26961; Mature: 26961

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTEKMIRQVVLDTETTGMNKGGTIYVGHRIIEIGCVEVINRRLTGRHFHVYVKPDREID
CCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEHHHHHHHHHHHCCCCEEEEEECCCCCCC
PEAIAVHGITDEFLHDKPAFSDIADEFIEFIKGAELVIHNAPFDVGFMDQEFRFLNKRTK
CCEEEEECCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCC
PTAEISTITDTLVMARKMYPGKRASLDALCRELGIDNKHRVLHGALLDAEILADVYLLMT
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEE
GGQKKLNLSSSGQNDTNTGKRVRKTQSPLTIISASEDEQQAHEKRLDLIEKSASCLWRE
CCCCEEECCCCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTEKMIRQVVLDTETTGMNKGGTIYVGHRIIEIGCVEVINRRLTGRHFHVYVKPDREID
CCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEHHHHHHHHHHHCCCCEEEEEECCCCCCC
PEAIAVHGITDEFLHDKPAFSDIADEFIEFIKGAELVIHNAPFDVGFMDQEFRFLNKRTK
CCEEEEECCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCC
PTAEISTITDTLVMARKMYPGKRASLDALCRELGIDNKHRVLHGALLDAEILADVYLLMT
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEE
GGQKKLNLSSSGQNDTNTGKRVRKTQSPLTIISASEDEQQAHEKRLDLIEKSASCLWRE
CCCCEEECCCCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]