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The map label for this gene is nagA [H]

Identifier: 119944264

GI number: 119944264

Start: 620898

End: 622031

Strand: Reverse

Name: nagA [H]

Synonym: Ping_0489

Alternate gene names: 119944264

Gene position: 622031-620898 (Counterclockwise)

Preceding gene: 119944265

Following gene: 119944263

Centisome position: 13.64

GC content: 42.06

Gene sequence:

>1134_bases
ATGTACGCATTAACAAATTGTAAAATTTATACAACAGACGCAGTGTTACTGGAACATGCTGTGATCGTAAAAAATAACAA
GATCGACAGTGTGATACCCATTGCAGAGCTCAGTTCAACGATCAAAAAAATTGATCTTCTTGGTGCCAACCTTTCGCCCG
GGTTTATCGATCTGCAACTGAACGGTTGTGGTGGTGTTATGTTTAATAATGAGATAACAGAAAAAACACTTGCGATAATG
CAATCTACTAATCTTAAATCAGGCTGTACCAGCTACCTGCCAACGCTTATCACATCGTCGGATGAAGATATGAGAACGGC
ACTCAAAGTGACACGGGATTATATAAATAAAAAGCCCAACGAAGTATTAGGCTTACATTTAGAGGGGCCTTATTTAAGTA
TCGAGAGAAAAGGGATTCATCGCTCCGAATATATCCGCAAAGCTGATATCTCTATGCTGGATCTTATTTGCCAAAATGCG
GATATCGTCAGTAAGGTCACGATTGCACCAGAAAAAAACTCGGTTGAGGTGATCCAGCGGCTTAGTAAAGCCGGGATTGT
TGTTGCGATAGGCCATACTAATGCCACCTACGCACAGGCAGCAGTGGCCATTGATAACGGTGCAACCTTTGCAACTCATC
TATTTAATGCCATGACCCCAATGACAGGTCGCGAACCGGGGGTTATTGGGGCGATTTATGATAAAAATATTTATGCCGGT
ATTATTGTGGATGGTTTCCATGTGGCTTACGAAAATGTCCGCATTTCGAAAAAAATAATGGCTGAAAAACTTATTTTAGT
CACGGATGCCACCGCCCCTGCCGGGGCTGATATTGAACAATTTGATTTTGTCGGCACTACGGTATATTACAAAGATGGGA
AATGTTTTGCCGCCGATGGTACACTGGGTGGCTCAGCCTTGACTATGATTGAAGCCATTGAAAAAAGTGTGAAGTTTGTT
GGAATTGAACTTGCAGAAGCGGTTCGCATGGCAACGTTATACCCTGCGAGGGCAATGTCTATTGCAAATAAAATAGGCAG
TATAAAATCGGGCAATATTGCCAATTTAGCCATTTTCAGCAGCGATTATAAAGTGACCGGCACAGTGCTCAATGGTGTGT
ATAAAGCATCTTAA

Upstream 100 bases:

>100_bases
TTTTGTCATCTGCTCAAAAGTTGGATTAAACAGTAAAAAACGGCAATATCTCCCGGCACGATTTGAACAGAAGCACTTAT
ATAAAATGGAGAAGTTTACA

Downstream 100 bases:

>100_bases
AAAGTATTTAAAAGTCAACAGATGGTGCCCATCGGAGCGGCTCAGGTCCGGTAATTAATGCCTGAACCGATGGATGTTAT
AAATAGAAGAAATGGTGCTA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MYALTNCKIYTTDAVLLEHAVIVKNNKIDSVIPIAELSSTIKKIDLLGANLSPGFIDLQLNGCGGVMFNNEITEKTLAIM
QSTNLKSGCTSYLPTLITSSDEDMRTALKVTRDYINKKPNEVLGLHLEGPYLSIERKGIHRSEYIRKADISMLDLICQNA
DIVSKVTIAPEKNSVEVIQRLSKAGIVVAIGHTNATYAQAAVAIDNGATFATHLFNAMTPMTGREPGVIGAIYDKNIYAG
IIVDGFHVAYENVRISKKIMAEKLILVTDATAPAGADIEQFDFVGTTVYYKDGKCFAADGTLGGSALTMIEAIEKSVKFV
GIELAEAVRMATLYPARAMSIANKIGSIKSGNIANLAIFSSDYKVTGTVLNGVYKAS

Sequences:

>Translated_377_residues
MYALTNCKIYTTDAVLLEHAVIVKNNKIDSVIPIAELSSTIKKIDLLGANLSPGFIDLQLNGCGGVMFNNEITEKTLAIM
QSTNLKSGCTSYLPTLITSSDEDMRTALKVTRDYINKKPNEVLGLHLEGPYLSIERKGIHRSEYIRKADISMLDLICQNA
DIVSKVTIAPEKNSVEVIQRLSKAGIVVAIGHTNATYAQAAVAIDNGATFATHLFNAMTPMTGREPGVIGAIYDKNIYAG
IIVDGFHVAYENVRISKKIMAEKLILVTDATAPAGADIEQFDFVGTTVYYKDGKCFAADGTLGGSALTMIEAIEKSVKFV
GIELAEAVRMATLYPARAMSIANKIGSIKSGNIANLAIFSSDYKVTGTVLNGVYKAS
>Mature_377_residues
MYALTNCKIYTTDAVLLEHAVIVKNNKIDSVIPIAELSSTIKKIDLLGANLSPGFIDLQLNGCGGVMFNNEITEKTLAIM
QSTNLKSGCTSYLPTLITSSDEDMRTALKVTRDYINKKPNEVLGLHLEGPYLSIERKGIHRSEYIRKADISMLDLICQNA
DIVSKVTIAPEKNSVEVIQRLSKAGIVVAIGHTNATYAQAAVAIDNGATFATHLFNAMTPMTGREPGVIGAIYDKNIYAG
IIVDGFHVAYENVRISKKIMAEKLILVTDATAPAGADIEQFDFVGTTVYYKDGKCFAADGTLGGSALTMIEAIEKSVKFV
GIELAEAVRMATLYPARAMSIANKIGSIKSGNIANLAIFSSDYKVTGTVLNGVYKAS

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=421, Percent_Identity=29.9287410926366, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI224922791, Length=415, Percent_Identity=29.8795180722892, Blast_Score=160, Evalue=3e-39,
Organism=Escherichia coli, GI1786892, Length=376, Percent_Identity=53.7234042553192, Blast_Score=429, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17553768, Length=394, Percent_Identity=30.2030456852792, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI19920392, Length=388, Percent_Identity=33.2474226804124, Blast_Score=191, Evalue=5e-49,
Organism=Drosophila melanogaster, GI281361140, Length=402, Percent_Identity=32.089552238806, Blast_Score=186, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40548; Mature: 40548

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYALTNCKIYTTDAVLLEHAVIVKNNKIDSVIPIAELSSTIKKIDLLGANLSPGFIDLQL
CEEEECCEEEEECHHHHHEEEEEECCCCCCEECHHHHHHHHHHHHHCCCCCCCCEEEEEE
NGCGGVMFNNEITEKTLAIMQSTNLKSGCTSYLPTLITSSDEDMRTALKVTRDYINKKPN
CCCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
EVLGLHLEGPYLSIERKGIHRSEYIRKADISMLDLICQNADIVSKVTIAPEKNSVEVIQR
CEEEEEECCCEEEEECCCCCHHHHHHHHCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHH
LSKAGIVVAIGHTNATYAQAAVAIDNGATFATHLFNAMTPMTGREPGVIGAIYDKNIYAG
HHHCCEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEE
IIVDGFHVAYENVRISKKIMAEKLILVTDATAPAGADIEQFDFVGTTVYYKDGKCFAADG
EEEECEEEEECCEEHHHHHHHCEEEEEEECCCCCCCCHHHEEEEEEEEEEECCEEEEECC
TLGGSALTMIEAIEKSVKFVGIELAEAVRMATLYPARAMSIANKIGSIKSGNIANLAIFS
CCCCHHHHHHHHHHHHHHEEEHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEEEEE
SDYKVTGTVLNGVYKAS
CCCEEEEEEECCEEECC
>Mature Secondary Structure
MYALTNCKIYTTDAVLLEHAVIVKNNKIDSVIPIAELSSTIKKIDLLGANLSPGFIDLQL
CEEEECCEEEEECHHHHHEEEEEECCCCCCEECHHHHHHHHHHHHHCCCCCCCCEEEEEE
NGCGGVMFNNEITEKTLAIMQSTNLKSGCTSYLPTLITSSDEDMRTALKVTRDYINKKPN
CCCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
EVLGLHLEGPYLSIERKGIHRSEYIRKADISMLDLICQNADIVSKVTIAPEKNSVEVIQR
CEEEEEECCCEEEEECCCCCHHHHHHHHCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHH
LSKAGIVVAIGHTNATYAQAAVAIDNGATFATHLFNAMTPMTGREPGVIGAIYDKNIYAG
HHHCCEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEE
IIVDGFHVAYENVRISKKIMAEKLILVTDATAPAGADIEQFDFVGTTVYYKDGKCFAADG
EEEECEEEEECCEEHHHHHHHCEEEEEEECCCCCCCCHHHEEEEEEEEEEECCEEEEECC
TLGGSALTMIEAIEKSVKFVGIELAEAVRMATLYPARAMSIANKIGSIKSGNIANLAIFS
CCCCHHHHHHHHHHHHHHEEEHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEEEEE
SDYKVTGTVLNGVYKAS
CCCEEEEEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]