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The map label for this gene is nagC [H]

Identifier: 119944263

GI number: 119944263

Start: 619437

End: 620663

Strand: Reverse

Name: nagC [H]

Synonym: Ping_0488

Alternate gene names: 119944263

Gene position: 620663-619437 (Counterclockwise)

Preceding gene: 119944264

Following gene: 119944259

Centisome position: 13.61

GC content: 39.28

Gene sequence:

>1227_bases
ATGGTACGAAATAATCAGCAAGCAGATTCCGTCATTGCCAGCGTTGATCATATTAAACAACTAAACAGTGCAACAATTTA
CAAAGTAATTGAAAAATACGCCCCTATTTCTCGCGTTAAGATTGCCAATGTAAGCAAACTAGCACCGGCCAGCGTAACCA
AAATCACCCGTCAACTTCTTCAACAGGGCATTATTTGCGAGACTGCACGACAAGCTTCAACCGGTGGTCGTTGTGCTATT
TCTCTGGCACCTAATACGGATAATATTCATGTCCTTGCGATTAAAATAGGGCAGAAAACATTATCTTTAAGTTGTTATAA
CTTAGCGGCCGAACAATTGACTACAAAAAAAATCAAGATAAAAAGTGAAGATGAACAGCAACTGCTTGCATTTCTGATTA
GCGAAATCGACAATTTCATCAAAAAACAACAAAAAAACATGGGAAAAATATCTGCTATTGCCATCTCTTTATCAGGTTTA
ATCAATCCAAAAAAAGGCGTTGTGCTCTATAGCCCCTACCACCCGTTAGTTAACTTTCCCTTGGCGAATAAAATTGAACA
GCATTTTCAGCTGCCTACTTTTATTGGTAACCATACGCGCTCATTAGCACTGGCTGAACACTATTTTGGTGCGTCGAAAG
AGTGTTTAGATTCGATTTTGATTAGCATTCACCATGGTGTTGGTTCGGGCATTATTATTGAGGGTAAAGCGTTATTAGGA
CAGAACTTTAATATTGGTGAAATAGGCCATATACAAGCAAATCCTGCGGGGCGGCAATGCCATTGTGGTAACTTTGGGTG
TTTAGAAACAGAAGTGAGTGATCGGGTTATTGTTGAGAAAGTGGCAATCGCTATCAAACAGGGCAGTTTTACCCGCTTAA
GCTTAGATTCCCTGAACATTGAAAAAATTTATCAGGCAGCAGAAGATAATGATCCCTTGTGTCAAAAGATAGTCGAAGAT
GCTGCAACCTATTTAGGTAAAGCCATCGCCATTTTAATTAATCTATTAAATCCGCAAAAAATCATTATTGCGGGTAAGAT
CATCCGCGCAAAAACAAGTTTATTATCCACCATTGAGCAATGTATCGCTCACCAGGTATTACCCAACTTTCAGCATAAAG
TGCAAATAGAGACCTCTCTATTAGAACCAGATACTACACTTGCCGCCTTTGCTTTGATCAAACAAGCCATTTATGAGGGC
GATTTACTGCAACAGATTCATGGCTAA

Upstream 100 bases:

>100_bases
GCTGTGTTCAAACTTGCAGCTCAGTCAGGGTTAATTTTAACAGGCAACCGGATCATCTTTTTAATTCGTTTGCCAGTATA
TTAAGGATCGGTAAATAACG

Downstream 100 bases:

>100_bases
AAGCCCGAAACTAGAAGCTAGAAGCTAGAAGCTAGAAACTCTCAGCTACCTTCATTATTCAAGCAATTTTGCAGATAATT
TTTGGACTTTTCTGTGGATA

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MVRNNQQADSVIASVDHIKQLNSATIYKVIEKYAPISRVKIANVSKLAPASVTKITRQLLQQGIICETARQASTGGRCAI
SLAPNTDNIHVLAIKIGQKTLSLSCYNLAAEQLTTKKIKIKSEDEQQLLAFLISEIDNFIKKQQKNMGKISAIAISLSGL
INPKKGVVLYSPYHPLVNFPLANKIEQHFQLPTFIGNHTRSLALAEHYFGASKECLDSILISIHHGVGSGIIIEGKALLG
QNFNIGEIGHIQANPAGRQCHCGNFGCLETEVSDRVIVEKVAIAIKQGSFTRLSLDSLNIEKIYQAAEDNDPLCQKIVED
AATYLGKAIAILINLLNPQKIIIAGKIIRAKTSLLSTIEQCIAHQVLPNFQHKVQIETSLLEPDTTLAAFALIKQAIYEG
DLLQQIHG

Sequences:

>Translated_408_residues
MVRNNQQADSVIASVDHIKQLNSATIYKVIEKYAPISRVKIANVSKLAPASVTKITRQLLQQGIICETARQASTGGRCAI
SLAPNTDNIHVLAIKIGQKTLSLSCYNLAAEQLTTKKIKIKSEDEQQLLAFLISEIDNFIKKQQKNMGKISAIAISLSGL
INPKKGVVLYSPYHPLVNFPLANKIEQHFQLPTFIGNHTRSLALAEHYFGASKECLDSILISIHHGVGSGIIIEGKALLG
QNFNIGEIGHIQANPAGRQCHCGNFGCLETEVSDRVIVEKVAIAIKQGSFTRLSLDSLNIEKIYQAAEDNDPLCQKIVED
AATYLGKAIAILINLLNPQKIIIAGKIIRAKTSLLSTIEQCIAHQVLPNFQHKVQIETSLLEPDTTLAAFALIKQAIYEG
DLLQQIHG
>Mature_408_residues
MVRNNQQADSVIASVDHIKQLNSATIYKVIEKYAPISRVKIANVSKLAPASVTKITRQLLQQGIICETARQASTGGRCAI
SLAPNTDNIHVLAIKIGQKTLSLSCYNLAAEQLTTKKIKIKSEDEQQLLAFLISEIDNFIKKQQKNMGKISAIAISLSGL
INPKKGVVLYSPYHPLVNFPLANKIEQHFQLPTFIGNHTRSLALAEHYFGASKECLDSILISIHHGVGSGIIIEGKALLG
QNFNIGEIGHIQANPAGRQCHCGNFGCLETEVSDRVIVEKVAIAIKQGSFTRLSLDSLNIEKIYQAAEDNDPLCQKIVED
AATYLGKAIAILINLLNPQKIIIAGKIIRAKTSLLSTIEQCIAHQVLPNFQHKVQIETSLLEPDTTLAAFALIKQAIYEG
DLLQQIHG

Specific function: Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=207, Percent_Identity=27.0531400966184, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI298566315, Length=207, Percent_Identity=27.0531400966184, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI190014632, Length=207, Percent_Identity=27.0531400966184, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4885285, Length=207, Percent_Identity=27.0531400966184, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786891, Length=395, Percent_Identity=44.5569620253165, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1787878, Length=405, Percent_Identity=33.5802469135802, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI87082127, Length=365, Percent_Identity=24.3835616438356, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI87081733, Length=288, Percent_Identity=24.3055555555556, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790522, Length=223, Percent_Identity=24.6636771300448, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082230, Length=216, Percent_Identity=29.1666666666667, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 44558; Mature: 44558

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRNNQQADSVIASVDHIKQLNSATIYKVIEKYAPISRVKIANVSKLAPASVTKITRQLL
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHEEECCCHHCCCHHHHHHHHHHH
QQGIICETARQASTGGRCAISLAPNTDNIHVLAIKIGQKTLSLSCYNLAAEQLTTKKIKI
HCCCHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEECCEEEEHHHHHHHHHHHHHHEEEE
KSEDEQQLLAFLISEIDNFIKKQQKNMGKISAIAISLSGLINPKKGVVLYSPYHPLVNFP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCCEEEECCCCCHHCCC
LANKIEQHFQLPTFIGNHTRSLALAEHYFGASKECLDSILISIHHGVGSGIIIEGKALLG
HHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHC
QNFNIGEIGHIQANPAGRQCHCGNFGCLETEVSDRVIVEKVAIAIKQGSFTRLSLDSLNI
CCCCCCCCCEEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCH
EKIYQAAEDNDPLCQKIVEDAATYLGKAIAILINLLNPQKIIIAGKIIRAKTSLLSTIEQ
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHH
CIAHQVLPNFQHKVQIETSLLEPDTTLAAFALIKQAIYEGDLLQQIHG
HHHHHHCCCCCCEEEEEEHCCCCCHHHHHHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure
MVRNNQQADSVIASVDHIKQLNSATIYKVIEKYAPISRVKIANVSKLAPASVTKITRQLL
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHEEECCCHHCCCHHHHHHHHHHH
QQGIICETARQASTGGRCAISLAPNTDNIHVLAIKIGQKTLSLSCYNLAAEQLTTKKIKI
HCCCHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEECCEEEEHHHHHHHHHHHHHHEEEE
KSEDEQQLLAFLISEIDNFIKKQQKNMGKISAIAISLSGLINPKKGVVLYSPYHPLVNFP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCCEEEECCCCCHHCCC
LANKIEQHFQLPTFIGNHTRSLALAEHYFGASKECLDSILISIHHGVGSGIIIEGKALLG
HHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHC
QNFNIGEIGHIQANPAGRQCHCGNFGCLETEVSDRVIVEKVAIAIKQGSFTRLSLDSLNI
CCCCCCCCCEEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCH
EKIYQAAEDNDPLCQKIVEDAATYLGKAIAILINLLNPQKIIIAGKIIRAKTSLLSTIEQ
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHH
CIAHQVLPNFQHKVQIETSLLEPDTTLAAFALIKQAIYEGDLLQQIHG
HHHHHHCCCCCCEEEEEEHCCCCCHHHHHHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]