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The map label for this gene is barA [H]

Identifier: 119944259

GI number: 119944259

Start: 612158

End: 615925

Strand: Reverse

Name: barA [H]

Synonym: Ping_0484

Alternate gene names: 119944259

Gene position: 615925-612158 (Counterclockwise)

Preceding gene: 119944263

Following gene: 119944258

Centisome position: 13.51

GC content: 46.92

Gene sequence:

>3768_bases
ATGAAAATCACTAAATACTTTCACTTTAATTTAGCTGCGGCAATGCCGTTGTTAACGCTGTTGATCACGTTTTTCATGAC
CTATGTGGCATTCAATACCGCCAAGATTGAACTCAAAAAAAACACGCAGACCTATTTTGATTTTCGTGTACGCGAGGCAA
TCAGCCTTATCAATAATCGCATGCATATTTATCAGCAGGTGTTGTACGGTGCGAGTGGTTTATTCATCGCCTCAAACAAT
ATCGAACGTGAGGAATTCAAAAAATATATTGCGACGCTCAATTTAACTAAGAACTATCCTGGCATACAAGGTGTAGGATT
CTCCCTAATTATACCATCAACAATAACTCAGCACGTTGCATCCATTCGTAGCGAAGGGTTCCCTGAATACACTATTTGGC
CTAAGGGGCAGGGTGATATTTCCACCGCTATCATCTACCTAGAGCCATTGGTTGATCGTAATCTGCGTGCATTCGGCTAT
GATATGTTCAGTGAGTCAGTGCGACATGCCGCCATGCAAAAAGCCATTGATACTGGTCTGCCTCAGCTGTCTGGAAAAAT
AAAGCTGGTACAGGAGACTGGCAAGCAAGACCAAGCTGGATTTTTGATGTATGTACCTATCTATCAGAATGGTACTAACA
ACGACACCCTAGCAGAACGGCAAGCGCATATCCTTGGCTGGGTATATTCACCTTTTCGGATGAATGATCTTATGGAAGGG
CTCTTTGGTGAACGGGCTAACGATATGGACATTCAGATATTCGATGGTGAAACTATGTCGAATGAAGCGTTACTGTATGA
TTCTAGTGCCGTTAATGTTGCGACGACTAACGAGTTTGAGGCTACTCGTATCTTACATATTGCCGACCATCCATGGACTG
TTCAGATCCGCCCTTTAGATTCAATGACTTCACGTATTAGGGCTGTTAGTCCAAATTTAGTTGCAAGTATTGGGATAATC
CTAAGCGTCTTTTTCACTGTATTGATTTGGTTCCTCGTGTCGGGACGAGAACGTGCTATTAATACGGCACGCTATATAAA
TAAAGAATTGAGCATCGAGCGACAACGCTTAAGTGACATCATTGATGCAACAAATTCCGGCACTTGGCAATGGAATATTC
AGACAGGTGAAGCCTTCTTTAATGACCATTGGCCCAGAGTCCTTGGTTATGAACTAAGCGAGCTTGGGCCTACTTCTTTT
GAAACGTGGCTTAAATTTATTCACCCAGAAGACAAGGAGCTATCGATAAAACGTTTACAAAAACATTTATCAGGCGAGTT
AGATTATTACGAATACGAAACACGGATGCGACATAAAAAGGGAGGCTGGGTTTGGGTGTTAGCCCGGGGAAAGGTAACGA
CATGGACTGCCGATGGCAAACCACTCTTGATGTGTGGAACGCATCAGGATATCACCAAACAGAAGTTTGCTACAGAACAA
CTACAGGATAGTGCAGCCCTGATAGAAGCTATTCTCAACACGGTAGTGGACGGCATCATCACCATCAATGAATATGGCAT
TGTAGAGAGCATCAATCCAGCGGCCGAACACATTTTTGGCTATAGTGCGACTGAAGTGATTGGGCATAACATCACAATGC
TGATGCCTGAATCTTATCGTAGTCAGCATGACGGTTATATTGAGCATTTCAATATCACTGGTGAGGCAAAAATAGTTGGT
ATTGACCGCATAATTGAGGGGAAACGCAAGAATGGTAGTATTTTCCCAATGGAATTGGGAGTGAGTAAAGTACTTCTGGG
CGAAAAGAAACTTTTCGCTAGTGTTGTCCGTGATATAACCGAACAAAAACGAGCCAAGCAGGCGCTAATTTCCGCCAAGA
CCGAGGCGGAAAAGGCTAACCTTGCCAAGTCACAGTTCCTCGCGGCCATGAGCCACGAAATCAGAACCCCCATGAACGGC
GTGATTGGTATGGTGGATGTGCTGCAACAAAGCAGCCTCAAGGGTTTCCAGGTCGACATGGTTGATACCATCCGTGATTC
TGCGTTTTCATTGCTGTCAATCATCGAAGATATTCTCGATTTCTCTAAAATTGAAGCTGGCAAACTGGACATTGAGTATG
CACCCATGGCCGTAGCCGAAGTAGTAGAGAAGGCTTGCTTTATGCTGGCTCATTTGGCTGAGAAGAAAAAGGTAGAACTG
ACGCTGTTCACTGATCCCGCGATTCCTGACATCACCCTAGGAGACGCCAATCGTCTGCGCCAGATTGTAGTTAATCTGAC
CAATAATGCCATCAAGTTTTCCAGCGGGTCAGATCGCCCCGGCCGCGTTTCGGTACAGGCCTTGATGACAGACCCGACCA
TGTTGGAGATCCGCGTGATTGATAACGGTATCGGCATGAATGAGTCCGCCCTATCAAAATTATTTATGCCATTTTACCAA
GCCGATGTCACGACGACTCGACGCTTCGGTGGTACGGGATTAGGAATCACTATCGCCCGTAATTTAGTGCAATTGATGGG
TGGTGAAATTACCGTGCAGAGCACACTGAATAAAGGCTCTATTTTCAGCGTGCACTTGCCTCTGGAGGCCATAACTGACA
TAGATCTAGAACAACCCCAACCAGAGGCGTGGACAGGGATAACTCCCGATCTATTCACTGGGCTTTCCTGCTTAGTGATA
GGTGACTCAGAGGGGCTGGCTGATCATCTGGCTGCCTATCTGAGCGCCGCTGGTGCAGTGGTCAATCAGTCCCCCAGCTT
GGCGGTAGCACAGAAGCAGGCCGTTACGACGACATCTGGACTGTCGGTATGGCTGGTTGACGCCAGCAATAACCCTCCAT
CCTCGGAGGAACTCCGCCTCATCGCAAGTGCCCAACCAGAACAGGCTATTCGTTTTGTCATTATCGGGCGCGGTAAACGT
CGATGCCCGCGTTGGCAAGATATCGATTTAAGCGTTGTTGTGGATGGTAATGTCCTGATGCGGCAGACCGTGCTGCAAGC
GGTCGCCATTGCTGCAGGGCTGGCGGAGCCGGAAGTAGAAAGGCTGCATGTAGGCAAAGGTGAGCAATCATTCGTGGCAC
CTTTGCGTAGCGACGCGCTAGCGCAAGGCAGATTGATTCTGGTAGCAGATGATAACCAAATCAACCAGAAGGTGATTGTG
CAGCAGCTTGCCTTACTTGGCTTTGCAGCTGATATTACCAGTAATGGCATTGAAGCATTGGCCCATTCGCACAGCGGCGA
TTATGCCCTGCTGTTAACTGATTTGCACATGCCCAAGATGGATGGCTATGAACTGACCGCCGCCATCCGCGCCGAAGAAA
ATGACCACCGTCATCTCCCAATCATAGCGATCACCGCTAACGCGCTGAAAGGCGAAGCACAACACTGTCTCGATGTTGGT
ATGGATGATTATATTAGCAAGCCAGTGCCATTAGAAAGTCTGATGGTCATCTTAGAGAAATGGCTGCCGCTTGCTGCAGC
AAAACCAGTGGATGTAAGTGTACTTACAGCGCTGGTAGGCGATGACCCTGAGATAATCAAAGACTTTCTGCAGCATTTTA
ATGATAGCGCAACAATGATTGCCACAGAGTTAACAACCGCCTGTGCCAACGGCGAGGTAGTGCAAGCCCAGGCTGCGGCG
CACAAACTAAAATCATCATCCCGCGCTGTAGGCGCAATGGTTTTGGGCGAATTGTGTGAAGAAATAGAGCTGGCGGCTAA
AGCCAATCAGCTTGAGGCCCTAACAGTATTAAAGCTTCGTTTTGAGGTGGAAATGGCCACCGTTAAAAAATATTTAGATA
AGCTATAA

Upstream 100 bases:

>100_bases
AATCATAAAATTAAATTCTTTATGCTGTTGTCGATACTGATATCACTAATACTTTTGCCTTATTGTAAGTGAGGCCCCAC
TCATAAATGATAAAACTGTA

Downstream 100 bases:

>100_bases
GCAACTGAAATTAAATATAATAATATAAAAATATAAAAAGGAAGTAATTATGGTTAGTAAATCGTCCCTCAACATTTTGA
TCATCGATGATCAGCCCTTT

Product: multi-sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1255; Mature: 1255

Protein sequence:

>1255_residues
MKITKYFHFNLAAAMPLLTLLITFFMTYVAFNTAKIELKKNTQTYFDFRVREAISLINNRMHIYQQVLYGASGLFIASNN
IEREEFKKYIATLNLTKNYPGIQGVGFSLIIPSTITQHVASIRSEGFPEYTIWPKGQGDISTAIIYLEPLVDRNLRAFGY
DMFSESVRHAAMQKAIDTGLPQLSGKIKLVQETGKQDQAGFLMYVPIYQNGTNNDTLAERQAHILGWVYSPFRMNDLMEG
LFGERANDMDIQIFDGETMSNEALLYDSSAVNVATTNEFEATRILHIADHPWTVQIRPLDSMTSRIRAVSPNLVASIGII
LSVFFTVLIWFLVSGRERAINTARYINKELSIERQRLSDIIDATNSGTWQWNIQTGEAFFNDHWPRVLGYELSELGPTSF
ETWLKFIHPEDKELSIKRLQKHLSGELDYYEYETRMRHKKGGWVWVLARGKVTTWTADGKPLLMCGTHQDITKQKFATEQ
LQDSAALIEAILNTVVDGIITINEYGIVESINPAAEHIFGYSATEVIGHNITMLMPESYRSQHDGYIEHFNITGEAKIVG
IDRIIEGKRKNGSIFPMELGVSKVLLGEKKLFASVVRDITEQKRAKQALISAKTEAEKANLAKSQFLAAMSHEIRTPMNG
VIGMVDVLQQSSLKGFQVDMVDTIRDSAFSLLSIIEDILDFSKIEAGKLDIEYAPMAVAEVVEKACFMLAHLAEKKKVEL
TLFTDPAIPDITLGDANRLRQIVVNLTNNAIKFSSGSDRPGRVSVQALMTDPTMLEIRVIDNGIGMNESALSKLFMPFYQ
ADVTTTRRFGGTGLGITIARNLVQLMGGEITVQSTLNKGSIFSVHLPLEAITDIDLEQPQPEAWTGITPDLFTGLSCLVI
GDSEGLADHLAAYLSAAGAVVNQSPSLAVAQKQAVTTTSGLSVWLVDASNNPPSSEELRLIASAQPEQAIRFVIIGRGKR
RCPRWQDIDLSVVVDGNVLMRQTVLQAVAIAAGLAEPEVERLHVGKGEQSFVAPLRSDALAQGRLILVADDNQINQKVIV
QQLALLGFAADITSNGIEALAHSHSGDYALLLTDLHMPKMDGYELTAAIRAEENDHRHLPIIAITANALKGEAQHCLDVG
MDDYISKPVPLESLMVILEKWLPLAAAKPVDVSVLTALVGDDPEIIKDFLQHFNDSATMIATELTTACANGEVVQAQAAA
HKLKSSSRAVGAMVLGELCEEIELAAKANQLEALTVLKLRFEVEMATVKKYLDKL

Sequences:

>Translated_1255_residues
MKITKYFHFNLAAAMPLLTLLITFFMTYVAFNTAKIELKKNTQTYFDFRVREAISLINNRMHIYQQVLYGASGLFIASNN
IEREEFKKYIATLNLTKNYPGIQGVGFSLIIPSTITQHVASIRSEGFPEYTIWPKGQGDISTAIIYLEPLVDRNLRAFGY
DMFSESVRHAAMQKAIDTGLPQLSGKIKLVQETGKQDQAGFLMYVPIYQNGTNNDTLAERQAHILGWVYSPFRMNDLMEG
LFGERANDMDIQIFDGETMSNEALLYDSSAVNVATTNEFEATRILHIADHPWTVQIRPLDSMTSRIRAVSPNLVASIGII
LSVFFTVLIWFLVSGRERAINTARYINKELSIERQRLSDIIDATNSGTWQWNIQTGEAFFNDHWPRVLGYELSELGPTSF
ETWLKFIHPEDKELSIKRLQKHLSGELDYYEYETRMRHKKGGWVWVLARGKVTTWTADGKPLLMCGTHQDITKQKFATEQ
LQDSAALIEAILNTVVDGIITINEYGIVESINPAAEHIFGYSATEVIGHNITMLMPESYRSQHDGYIEHFNITGEAKIVG
IDRIIEGKRKNGSIFPMELGVSKVLLGEKKLFASVVRDITEQKRAKQALISAKTEAEKANLAKSQFLAAMSHEIRTPMNG
VIGMVDVLQQSSLKGFQVDMVDTIRDSAFSLLSIIEDILDFSKIEAGKLDIEYAPMAVAEVVEKACFMLAHLAEKKKVEL
TLFTDPAIPDITLGDANRLRQIVVNLTNNAIKFSSGSDRPGRVSVQALMTDPTMLEIRVIDNGIGMNESALSKLFMPFYQ
ADVTTTRRFGGTGLGITIARNLVQLMGGEITVQSTLNKGSIFSVHLPLEAITDIDLEQPQPEAWTGITPDLFTGLSCLVI
GDSEGLADHLAAYLSAAGAVVNQSPSLAVAQKQAVTTTSGLSVWLVDASNNPPSSEELRLIASAQPEQAIRFVIIGRGKR
RCPRWQDIDLSVVVDGNVLMRQTVLQAVAIAAGLAEPEVERLHVGKGEQSFVAPLRSDALAQGRLILVADDNQINQKVIV
QQLALLGFAADITSNGIEALAHSHSGDYALLLTDLHMPKMDGYELTAAIRAEENDHRHLPIIAITANALKGEAQHCLDVG
MDDYISKPVPLESLMVILEKWLPLAAAKPVDVSVLTALVGDDPEIIKDFLQHFNDSATMIATELTTACANGEVVQAQAAA
HKLKSSSRAVGAMVLGELCEEIELAAKANQLEALTVLKLRFEVEMATVKKYLDKL
>Mature_1255_residues
MKITKYFHFNLAAAMPLLTLLITFFMTYVAFNTAKIELKKNTQTYFDFRVREAISLINNRMHIYQQVLYGASGLFIASNN
IEREEFKKYIATLNLTKNYPGIQGVGFSLIIPSTITQHVASIRSEGFPEYTIWPKGQGDISTAIIYLEPLVDRNLRAFGY
DMFSESVRHAAMQKAIDTGLPQLSGKIKLVQETGKQDQAGFLMYVPIYQNGTNNDTLAERQAHILGWVYSPFRMNDLMEG
LFGERANDMDIQIFDGETMSNEALLYDSSAVNVATTNEFEATRILHIADHPWTVQIRPLDSMTSRIRAVSPNLVASIGII
LSVFFTVLIWFLVSGRERAINTARYINKELSIERQRLSDIIDATNSGTWQWNIQTGEAFFNDHWPRVLGYELSELGPTSF
ETWLKFIHPEDKELSIKRLQKHLSGELDYYEYETRMRHKKGGWVWVLARGKVTTWTADGKPLLMCGTHQDITKQKFATEQ
LQDSAALIEAILNTVVDGIITINEYGIVESINPAAEHIFGYSATEVIGHNITMLMPESYRSQHDGYIEHFNITGEAKIVG
IDRIIEGKRKNGSIFPMELGVSKVLLGEKKLFASVVRDITEQKRAKQALISAKTEAEKANLAKSQFLAAMSHEIRTPMNG
VIGMVDVLQQSSLKGFQVDMVDTIRDSAFSLLSIIEDILDFSKIEAGKLDIEYAPMAVAEVVEKACFMLAHLAEKKKVEL
TLFTDPAIPDITLGDANRLRQIVVNLTNNAIKFSSGSDRPGRVSVQALMTDPTMLEIRVIDNGIGMNESALSKLFMPFYQ
ADVTTTRRFGGTGLGITIARNLVQLMGGEITVQSTLNKGSIFSVHLPLEAITDIDLEQPQPEAWTGITPDLFTGLSCLVI
GDSEGLADHLAAYLSAAGAVVNQSPSLAVAQKQAVTTTSGLSVWLVDASNNPPSSEELRLIASAQPEQAIRFVIIGRGKR
RCPRWQDIDLSVVVDGNVLMRQTVLQAVAIAAGLAEPEVERLHVGKGEQSFVAPLRSDALAQGRLILVADDNQINQKVIV
QQLALLGFAADITSNGIEALAHSHSGDYALLLTDLHMPKMDGYELTAAIRAEENDHRHLPIIAITANALKGEAQHCLDVG
MDDYISKPVPLESLMVILEKWLPLAAAKPVDVSVLTALVGDDPEIIKDFLQHFNDSATMIATELTTACANGEVVQAQAAA
HKLKSSSRAVGAMVLGELCEEIELAAKANQLEALTVLKLRFEVEMATVKKYLDKL

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=274, Percent_Identity=41.6058394160584, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI145693157, Length=308, Percent_Identity=34.7402597402597, Blast_Score=170, Evalue=7e-43,
Organism=Escherichia coli, GI87081816, Length=243, Percent_Identity=37.4485596707819, Blast_Score=157, Evalue=6e-39,
Organism=Escherichia coli, GI48994928, Length=254, Percent_Identity=35.4330708661417, Blast_Score=149, Evalue=1e-36,
Organism=Escherichia coli, GI1788713, Length=408, Percent_Identity=25.2450980392157, Blast_Score=133, Evalue=6e-32,
Organism=Escherichia coli, GI1788549, Length=375, Percent_Identity=24, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1786600, Length=413, Percent_Identity=23.9709443099274, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1788393, Length=277, Percent_Identity=26.3537906137184, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1790436, Length=258, Percent_Identity=25.1937984496124, Blast_Score=80, Evalue=9e-16,
Organism=Escherichia coli, GI1788279, Length=226, Percent_Identity=25.6637168141593, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1786912, Length=267, Percent_Identity=23.5955056179775, Blast_Score=77, Evalue=7e-15,
Organism=Escherichia coli, GI87081921, Length=118, Percent_Identity=35.5932203389831, Blast_Score=77, Evalue=9e-15,
Organism=Escherichia coli, GI1790861, Length=248, Percent_Identity=24.5967741935484, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1790346, Length=238, Percent_Identity=25.2100840336134, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1786783, Length=226, Percent_Identity=26.5486725663717, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI87082012, Length=110, Percent_Identity=31.8181818181818, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1790300, Length=369, Percent_Identity=23.3062330623306, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=24.5689655172414, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=89, Percent_Identity=39.3258426966292, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR019247
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF09984 DUF2222; PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 138749; Mature: 138749

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50839 CHASE ; PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITKYFHFNLAAAMPLLTLLITFFMTYVAFNTAKIELKKNTQTYFDFRVREAISLINNR
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
MHIYQQVLYGASGLFIASNNIEREEFKKYIATLNLTKNYPGIQGVGFSLIIPSTITQHVA
HHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHEEECCCCCCCCCCCEEEECCHHHHHHHH
SIRSEGFPEYTIWPKGQGDISTAIIYLEPLVDRNLRAFGYDMFSESVRHAAMQKAIDTGL
HHHHCCCCCEEECCCCCCCCEEEEEEEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PQLSGKIKLVQETGKQDQAGFLMYVPIYQNGTNNDTLAERQAHILGWVYSPFRMNDLMEG
CCCCCCEEEEECCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHEEEECCHHHHHHHHH
LFGERANDMDIQIFDGETMSNEALLYDSSAVNVATTNEFEATRILHIADHPWTVQIRPLD
HHCCCCCCCEEEEECCCCCCCCEEEEECCCEEEEECCCCCCEEEEEEECCCEEEEEEEHH
SMTSRIRAVSPNLVASIGIILSVFFTVLIWFLVSGRERAINTARYINKELSIERQRLSDI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
IDATNSGTWQWNIQTGEAFFNDHWPRVLGYELSELGPTSFETWLKFIHPEDKELSIKRLQ
HHCCCCCEEEEEEECCCHHHCCCCCHHHCCCHHHCCCCCHHHHHHHHCCCCCCHHHHHHH
KHLSGELDYYEYETRMRHKKGGWVWVLARGKVTTWTADGKPLLMCGTHQDITKQKFATEQ
HHHCCCCCHHHHHHHHHHCCCCEEEEEECCEEEEEECCCCEEEEECCCCHHHHHHHHHHH
LQDSAALIEAILNTVVDGIITINEYGIVESINPAAEHIFGYSATEVIGHNITMLMPESYR
HHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHCCCCHHHHHCCCEEEEECHHHC
SQHDGYIEHFNITGEAKIVGIDRIIEGKRKNGSIFPMELGVSKVLLGEKKLFASVVRDIT
CCCCCCEEEEEECCCEEEEEHHHHHCCCCCCCCEEEEHHCCHHHHHCHHHHHHHHHHHHH
EQKRAKQALISAKTEAEKANLAKSQFLAAMSHEIRTPMNGVIGMVDVLQQSSLKGFQVDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEHH
VDTIRDSAFSLLSIIEDILDFSKIEAGKLDIEYAPMAVAEVVEKACFMLAHLAEKKKVEL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEE
TLFTDPAIPDITLGDANRLRQIVVNLTNNAIKFSSGSDRPGRVSVQALMTDPTMLEIRVI
EEEECCCCCCEECCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEEECCCEEEEEEEE
DNGIGMNESALSKLFMPFYQADVTTTRRFGGTGLGITIARNLVQLMGGEITVQSTLNKGS
ECCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCC
IFSVHLPLEAITDIDLEQPQPEAWTGITPDLFTGLSCLVIGDSEGLADHLAAYLSAAGAV
EEEEEECHHHHCCCCCCCCCCCCCCCCCHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHH
VNQSPSLAVAQKQAVTTTSGLSVWLVDASNNPPSSEELRLIASAQPEQAIRFVIIGRGKR
HCCCCCEEEHHHHHEEEECCCEEEEEECCCCCCCHHHEEEEECCCCCCCEEEEEEECCCC
RCPRWQDIDLSVVVDGNVLMRQTVLQAVAIAAGLAEPEVERLHVGKGEQSFVAPLRSDAL
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHEECCCCCHHHHHHHHHHHH
AQGRLILVADDNQINQKVIVQQLALLGFAADITSNGIEALAHSHSGDYALLLTDLHMPKM
HCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEEECCCCCC
DGYELTAAIRAEENDHRHLPIIAITANALKGEAQHCLDVGMDDYISKPVPLESLMVILEK
CCEEEEEEEEECCCCCCCCCEEEEECCHHCCCHHHHHHCCCHHHCCCCCCHHHHHHHHHH
WLPLAAAKPVDVSVLTALVGDDPEIIKDFLQHFNDSATMIATELTTACANGEVVQAQAAA
HCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCEEEHHHHH
HKLKSSSRAVGAMVLGELCEEIELAAKANQLEALTVLKLRFEVEMATVKKYLDKL
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEEEEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MKITKYFHFNLAAAMPLLTLLITFFMTYVAFNTAKIELKKNTQTYFDFRVREAISLINNR
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
MHIYQQVLYGASGLFIASNNIEREEFKKYIATLNLTKNYPGIQGVGFSLIIPSTITQHVA
HHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHEEECCCCCCCCCCCEEEECCHHHHHHHH
SIRSEGFPEYTIWPKGQGDISTAIIYLEPLVDRNLRAFGYDMFSESVRHAAMQKAIDTGL
HHHHCCCCCEEECCCCCCCCEEEEEEEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PQLSGKIKLVQETGKQDQAGFLMYVPIYQNGTNNDTLAERQAHILGWVYSPFRMNDLMEG
CCCCCCEEEEECCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHEEEECCHHHHHHHHH
LFGERANDMDIQIFDGETMSNEALLYDSSAVNVATTNEFEATRILHIADHPWTVQIRPLD
HHCCCCCCCEEEEECCCCCCCCEEEEECCCEEEEECCCCCCEEEEEEECCCEEEEEEEHH
SMTSRIRAVSPNLVASIGIILSVFFTVLIWFLVSGRERAINTARYINKELSIERQRLSDI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
IDATNSGTWQWNIQTGEAFFNDHWPRVLGYELSELGPTSFETWLKFIHPEDKELSIKRLQ
HHCCCCCEEEEEEECCCHHHCCCCCHHHCCCHHHCCCCCHHHHHHHHCCCCCCHHHHHHH
KHLSGELDYYEYETRMRHKKGGWVWVLARGKVTTWTADGKPLLMCGTHQDITKQKFATEQ
HHHCCCCCHHHHHHHHHHCCCCEEEEEECCEEEEEECCCCEEEEECCCCHHHHHHHHHHH
LQDSAALIEAILNTVVDGIITINEYGIVESINPAAEHIFGYSATEVIGHNITMLMPESYR
HHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHCCCCHHHHHCCCEEEEECHHHC
SQHDGYIEHFNITGEAKIVGIDRIIEGKRKNGSIFPMELGVSKVLLGEKKLFASVVRDIT
CCCCCCEEEEEECCCEEEEEHHHHHCCCCCCCCEEEEHHCCHHHHHCHHHHHHHHHHHHH
EQKRAKQALISAKTEAEKANLAKSQFLAAMSHEIRTPMNGVIGMVDVLQQSSLKGFQVDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEHH
VDTIRDSAFSLLSIIEDILDFSKIEAGKLDIEYAPMAVAEVVEKACFMLAHLAEKKKVEL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEE
TLFTDPAIPDITLGDANRLRQIVVNLTNNAIKFSSGSDRPGRVSVQALMTDPTMLEIRVI
EEEECCCCCCEECCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEEECCCEEEEEEEE
DNGIGMNESALSKLFMPFYQADVTTTRRFGGTGLGITIARNLVQLMGGEITVQSTLNKGS
ECCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCC
IFSVHLPLEAITDIDLEQPQPEAWTGITPDLFTGLSCLVIGDSEGLADHLAAYLSAAGAV
EEEEEECHHHHCCCCCCCCCCCCCCCCCHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHH
VNQSPSLAVAQKQAVTTTSGLSVWLVDASNNPPSSEELRLIASAQPEQAIRFVIIGRGKR
HCCCCCEEEHHHHHEEEECCCEEEEEECCCCCCCHHHEEEEECCCCCCCEEEEEEECCCC
RCPRWQDIDLSVVVDGNVLMRQTVLQAVAIAAGLAEPEVERLHVGKGEQSFVAPLRSDAL
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHEECCCCCHHHHHHHHHHHH
AQGRLILVADDNQINQKVIVQQLALLGFAADITSNGIEALAHSHSGDYALLLTDLHMPKM
HCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEEECCCCCC
DGYELTAAIRAEENDHRHLPIIAITANALKGEAQHCLDVGMDDYISKPVPLESLMVILEK
CCEEEEEEEEECCCCCCCCCEEEEECCHHCCCHHHHHHCCCHHHCCCCCCHHHHHHHHHH
WLPLAAAKPVDVSVLTALVGDDPEIIKDFLQHFNDSATMIATELTTACANGEVVQAQAAA
HCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCEEEHHHHH
HKLKSSSRAVGAMVLGELCEEIELAAKANQLEALTVLKLRFEVEMATVKKYLDKL
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEEEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]