| Definition | Psychromonas ingrahamii 37, complete genome. |
|---|---|
| Accession | NC_008709 |
| Length | 4,559,598 |
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The map label for this gene is fabG [C]
Identifier: 119944009
GI number: 119944009
Start: 281415
End: 282098
Strand: Reverse
Name: fabG [C]
Synonym: Ping_0223
Alternate gene names: 119944009
Gene position: 282098-281415 (Counterclockwise)
Preceding gene: 119944010
Following gene: 119944007
Centisome position: 6.19
GC content: 44.44
Gene sequence:
>684_bases ATGAATTATCAAACGGTATTTATTACTGGTGCTACAAAGGGCCTAGGTCGAGCACTAGTAATAGATCTTTGCAGCAAAGG ATATAAAGTCTTTGCAACCGGACGTGATGAAACTCAGCTGCAGCAACTTATGCAGCAAACAGGCTGCTTAGGGGTCAGTT GCGACCTCAGCCAAGCAGAAGCTGCAGTTGAAATTTTTCAGAAAGCCACAAAAGCGCTGGGCCATATTGATGTGCTTATT AATAATGCCGGCATGAATTCACGAAAATGCGAATTAGCCGAGACAACATTAGAAGAGTTTGAACAACAGTATGCAGTCAA TTTACGTGCGCCTTATTTACTTTGCCGGGAAGCAATGCAGCAGATGTTACCTAAAGAGCATGGTTATATTATCAATATTG TCAGTACGGCAGCTAAACGCAGTAATCCAACCATGAGTATTTATAGCGCAATGAAACAGGGATTTGCCGGGTTGAATAAT GTCTTAATGAAAGAAGCACAGCCCCATGGTATCAAAGTAACTGCCGTTTACCCCGGAGGAATGAATACCGCCTTCCGCGA GCAGGAACGTCCGCAATATATGCAGCCTGCGAGCGTAGCAACACTGGTTAGCCAATTACTCAGCAATCCCATCGATGTCG TGATCCATGAATTGACTTGCCGTCCTATGGTTGAGCTGGAATAG
Upstream 100 bases:
>100_bases AAGCGCTGCGCAAAGTACTTAGCCGTTTGTTGCTCTATTAAAAAGGTAACGCATCACGGCTGATGCTTTTAATTGCTAAT TAACCTAAGGAAGCAAAAAC
Downstream 100 bases:
>100_bases TCAAAACTAAAAAAGAAATTAAAAGCCCGGGAGAGTGACTCGGGCATCCCCTTAGGATTGTACTAGCCTAAATTGTGCTA ATTGCCTACCATTGCAGGCC
Product: short-chain dehydrogenase/reductase SDR
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 227; Mature: 227
Protein sequence:
>227_residues MNYQTVFITGATKGLGRALVIDLCSKGYKVFATGRDETQLQQLMQQTGCLGVSCDLSQAEAAVEIFQKATKALGHIDVLI NNAGMNSRKCELAETTLEEFEQQYAVNLRAPYLLCREAMQQMLPKEHGYIINIVSTAAKRSNPTMSIYSAMKQGFAGLNN VLMKEAQPHGIKVTAVYPGGMNTAFREQERPQYMQPASVATLVSQLLSNPIDVVIHELTCRPMVELE
Sequences:
>Translated_227_residues MNYQTVFITGATKGLGRALVIDLCSKGYKVFATGRDETQLQQLMQQTGCLGVSCDLSQAEAAVEIFQKATKALGHIDVLI NNAGMNSRKCELAETTLEEFEQQYAVNLRAPYLLCREAMQQMLPKEHGYIINIVSTAAKRSNPTMSIYSAMKQGFAGLNN VLMKEAQPHGIKVTAVYPGGMNTAFREQERPQYMQPASVATLVSQLLSNPIDVVIHELTCRPMVELE >Mature_227_residues MNYQTVFITGATKGLGRALVIDLCSKGYKVFATGRDETQLQQLMQQTGCLGVSCDLSQAEAAVEIFQKATKALGHIDVLI NNAGMNSRKCELAETTLEEFEQQYAVNLRAPYLLCREAMQQMLPKEHGYIINIVSTAAKRSNPTMSIYSAMKQGFAGLNN VLMKEAQPHGIKVTAVYPGGMNTAFREQERPQYMQPASVATLVSQLLSNPIDVVIHELTCRPMVELE
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=194, Percent_Identity=29.8969072164948, Blast_Score=98, Evalue=6e-21, Organism=Homo sapiens, GI109715829, Length=243, Percent_Identity=28.8065843621399, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI7705925, Length=180, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI32483357, Length=219, Percent_Identity=26.4840182648402, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI20149619, Length=189, Percent_Identity=28.042328042328, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI209862901, Length=195, Percent_Identity=28.7179487179487, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI19923983, Length=195, Percent_Identity=28.7179487179487, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=26.9230769230769, Blast_Score=77, Evalue=8e-15, Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=26.6331658291457, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI5031737, Length=192, Percent_Identity=26.5625, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI31542939, Length=209, Percent_Identity=26.7942583732057, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI4504505, Length=214, Percent_Identity=26.1682242990654, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI4503817, Length=202, Percent_Identity=27.7227722772277, Blast_Score=71, Evalue=6e-13, Organism=Homo sapiens, GI59889578, Length=188, Percent_Identity=25.531914893617, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI15277342, Length=221, Percent_Identity=27.1493212669683, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI40807363, Length=193, Percent_Identity=27.4611398963731, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI142976729, Length=190, Percent_Identity=25.7894736842105, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI210032110, Length=218, Percent_Identity=22.9357798165138, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1787335, Length=210, Percent_Identity=30, Blast_Score=97, Evalue=7e-22, Organism=Escherichia coli, GI2367365, Length=217, Percent_Identity=28.110599078341, Blast_Score=84, Evalue=9e-18, Organism=Escherichia coli, GI1789208, Length=202, Percent_Identity=25.2475247524752, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1787820, Length=176, Percent_Identity=28.4090909090909, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1788459, Length=188, Percent_Identity=29.2553191489362, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI87082160, Length=183, Percent_Identity=28.4153005464481, Blast_Score=74, Evalue=5e-15, Organism=Escherichia coli, GI1789378, Length=202, Percent_Identity=28.7128712871287, Blast_Score=74, Evalue=7e-15, Organism=Escherichia coli, GI2367175, Length=183, Percent_Identity=28.4153005464481, Blast_Score=70, Evalue=9e-14, Organism=Escherichia coli, GI1786701, Length=188, Percent_Identity=28.7234042553192, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1790717, Length=189, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1787526, Length=222, Percent_Identity=23.8738738738739, Blast_Score=67, Evalue=8e-13, Organism=Escherichia coli, GI1786812, Length=180, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI87082100, Length=225, Percent_Identity=23.1111111111111, Blast_Score=64, Evalue=6e-12, Organism=Caenorhabditis elegans, GI193204405, Length=196, Percent_Identity=26.530612244898, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17560220, Length=196, Percent_Identity=26.530612244898, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17531453, Length=196, Percent_Identity=26.530612244898, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI71994604, Length=181, Percent_Identity=28.7292817679558, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562908, Length=231, Percent_Identity=24.2424242424242, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI25152911, Length=199, Percent_Identity=26.1306532663317, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17559104, Length=194, Percent_Identity=28.3505154639175, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI32563809, Length=202, Percent_Identity=25.7425742574257, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17507613, Length=202, Percent_Identity=25.7425742574257, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17538486, Length=199, Percent_Identity=27.6381909547739, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17564282, Length=189, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17560150, Length=197, Percent_Identity=26.3959390862944, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17562906, Length=196, Percent_Identity=25, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17563726, Length=192, Percent_Identity=27.0833333333333, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17508895, Length=189, Percent_Identity=25.3968253968254, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17560176, Length=183, Percent_Identity=27.3224043715847, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI115534694, Length=181, Percent_Identity=27.6243093922652, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17562910, Length=196, Percent_Identity=29.0816326530612, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI193203115, Length=188, Percent_Identity=28.1914893617021, Blast_Score=70, Evalue=6e-13, Organism=Caenorhabditis elegans, GI193203117, Length=188, Percent_Identity=28.1914893617021, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI72000259, Length=193, Percent_Identity=26.9430051813472, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17508651, Length=178, Percent_Identity=28.6516853932584, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI71994600, Length=182, Percent_Identity=26.3736263736264, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17551412, Length=197, Percent_Identity=25.8883248730964, Blast_Score=68, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17562990, Length=192, Percent_Identity=24.4791666666667, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17557668, Length=203, Percent_Identity=26.1083743842365, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17560332, Length=199, Percent_Identity=25.6281407035176, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17559552, Length=201, Percent_Identity=26.865671641791, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17568967, Length=224, Percent_Identity=23.2142857142857, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17562904, Length=194, Percent_Identity=25.7731958762887, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17565030, Length=194, Percent_Identity=26.8041237113402, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17561402, Length=186, Percent_Identity=22.0430107526882, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=187, Percent_Identity=32.620320855615, Blast_Score=82, Evalue=1e-16, Organism=Saccharomyces cerevisiae, GI6322067, Length=189, Percent_Identity=31.7460317460317, Blast_Score=69, Evalue=6e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=26.5625, Blast_Score=66, Evalue=4e-12, Organism=Drosophila melanogaster, GI24641388, Length=243, Percent_Identity=30.0411522633745, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI281364494, Length=241, Percent_Identity=27.8008298755187, Blast_Score=85, Evalue=5e-17, Organism=Drosophila melanogaster, GI24643142, Length=179, Percent_Identity=33.5195530726257, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI116007236, Length=237, Percent_Identity=27.4261603375527, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI21355319, Length=187, Percent_Identity=24.0641711229947, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI24639444, Length=192, Percent_Identity=28.6458333333333, Blast_Score=75, Evalue=2e-14, Organism=Drosophila melanogaster, GI23397609, Length=182, Percent_Identity=29.1208791208791, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI28571526, Length=183, Percent_Identity=29.5081967213115, Blast_Score=74, Evalue=8e-14, Organism=Drosophila melanogaster, GI24644339, Length=189, Percent_Identity=29.1005291005291, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI21357041, Length=221, Percent_Identity=28.9592760180996, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24641232, Length=243, Percent_Identity=25.1028806584362, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24663911, Length=246, Percent_Identity=23.9837398373984, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI21358495, Length=189, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI116007234, Length=241, Percent_Identity=27.8008298755187, Blast_Score=65, Evalue=2e-11, Organism=Drosophila melanogaster, GI24640492, Length=215, Percent_Identity=23.7209302325581, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 25037; Mature: 25037
Theoretical pI: Translated: 6.90; Mature: 6.90
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.6 %Cys (Translated Protein) 4.8 %Met (Translated Protein) 7.5 %Cys+Met (Translated Protein) 2.6 %Cys (Mature Protein) 4.8 %Met (Mature Protein) 7.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNYQTVFITGATKGLGRALVIDLCSKGYKVFATGRDETQLQQLMQQTGCLGVSCDLSQAE CCCEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCEEECCHHHHH AAVEIFQKATKALGHIDVLINNAGMNSRKCELAETTLEEFEQQYAVNLRAPYLLCREAMQ HHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH QMLPKEHGYIINIVSTAAKRSNPTMSIYSAMKQGFAGLNNVLMKEAQPHGIKVTAVYPGG HHCCCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC MNTAFREQERPQYMQPASVATLVSQLLSNPIDVVIHELTCRPMVELE CCHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCC >Mature Secondary Structure MNYQTVFITGATKGLGRALVIDLCSKGYKVFATGRDETQLQQLMQQTGCLGVSCDLSQAE CCCEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCEEECCHHHHH AAVEIFQKATKALGHIDVLINNAGMNSRKCELAETTLEEFEQQYAVNLRAPYLLCREAMQ HHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH QMLPKEHGYIINIVSTAAKRSNPTMSIYSAMKQGFAGLNNVLMKEAQPHGIKVTAVYPGG HHCCCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC MNTAFREQERPQYMQPASVATLVSQLLSNPIDVVIHELTCRPMVELE CCHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11418146 [H]