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The map label for this gene is xylB [H]

Identifier: 119944010

GI number: 119944010

Start: 282480

End: 283931

Strand: Reverse

Name: xylB [H]

Synonym: Ping_0224

Alternate gene names: 119944010

Gene position: 283931-282480 (Counterclockwise)

Preceding gene: 119944011

Following gene: 119944009

Centisome position: 6.23

GC content: 45.59

Gene sequence:

>1452_bases
ATGTTTATTGGTATTGATCTTGGAACGTCTGGAGTAAAAGTCATTTTAGTTGATCAAAGTGGACTTATTTTAGGAACAAA
AACTGTCTCAATATCGGTGTCACGACCTGCACCACTATGGTCAGAGCAGGATCCGGCAGAATGGTGGAGCGCAACCAATC
AAGCAATTAAAGCACTCGCCAAAGATATCAGCTTATCTAATGTTAGTGCGATTGGATTAGCAGGACAAATGCACGGTGCT
GCATTACTGGATGACAATGGCAAAGTCCTTCGTCCTGCTATTTTATGGAATGATGGACGATGCGCGGAAGAATGCCTCGA
AATGGAGCAGTTAGTACCAACAAGCAGGGATATTACCGGCAATATTATGATGCCGGGATTTACCGCCCCTAAATTAAAAT
GGGTACAAAAAAACGAGCCGGAATGCTTCGCTAAGATAGCGAAGGTATTACTGCCAAAAGATTATCTGCGCTACTGCATG
ACGGGAGATTTTGCATCCGACATGTCGGATGCGGCAGGCACTATGTGGCTTGATGTGGCAAAACGGGATTGGAATGCTCA
ACTACTAGCGGCAACAGGGTTAACCCGTCAGCAAATGCCTAAATTATATGAAGGTAGCCAAATCACAGGCACCTTATCAA
AAGAGCTTGCTAATGAATGGGGGATGCCTTGTGTCCCCGTCGTTGCAGGGGCTGGTGATAATGCTGCGGGCGCAATTGGA
GTGGGTATTACCCAGCCCAGACAAGCGATGCTTTCACTTGGAACATCCGGGGTATATTTTGCCGTTAGTGATGGTTTCAG
CGCAAACCCAGAATCAGCATTACATAGCTTCTGCCATGCCTTACCAGCAACATGGCACACAATGTCCGTGATATTAAGTG
CCGCTTCTTGTTTAACCTGGGTCGCAGAATTAACGGGAGCATCAAGTGTTCCTGAGATGATTGCCGAGGTTGAAGCGGAT
GCTGATCTAAATTCAGAAGTGATTTTTCTTCCTTATCTGTCTGGAGAGCGTACACCGCATAACAACCCTGATGCTAAAGG
TGTATTTTTTGGTATGACACACGCGACTAAACGTGCAGAGTTAGCTCAAGCCGTCTTAGAAGGGGTTGGTTTTGCTTTAG
CTGATGGCTTAGATGCACTCCATGCAACAGGCGTCGAGCCGGAAGAGATTTCATTAATTGGTGGCGGCGCACAAAGTGCT
TATTGGCGCCAAATGTTAGCTGATATTTTCAATAAAAAGCTCGCTTATCGAGTTGGTGGGGATGTGGGACCCGCATTAGG
TGCTGCGCGACTTGCTCGCCTAGGGTTAGCAGGACAAGAAAAACTTTCAGAAGTTTGCCCCGTTCCAAGACTGATTCAAA
CTCATCTTCCCAATATTGGAAAGCATGCGGCTTATGCACTGAAGCGCGAAAAATTTCAAAAAATTTATGTCCAATTAAAG
GATATTTTTTAA

Upstream 100 bases:

>100_bases
CCAAGCAGAGAGATCGTCTTTCTCATATAAAGACTCATTCTTCGCTTTATAAATAATATAAAATGAAGCAATTTTATATT
ATATAGAAAAGGAACCTTGT

Downstream 100 bases:

>100_bases
ATCAATACTTCCAATAAGTAAGGCATTGATAATCATTAATGCTTTACTTGGCAATATAAAAACCACCGCGATTATGTTAA
TACGCTAACCCCTAGGTCAG

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MFIGIDLGTSGVKVILVDQSGLILGTKTVSISVSRPAPLWSEQDPAEWWSATNQAIKALAKDISLSNVSAIGLAGQMHGA
ALLDDNGKVLRPAILWNDGRCAEECLEMEQLVPTSRDITGNIMMPGFTAPKLKWVQKNEPECFAKIAKVLLPKDYLRYCM
TGDFASDMSDAAGTMWLDVAKRDWNAQLLAATGLTRQQMPKLYEGSQITGTLSKELANEWGMPCVPVVAGAGDNAAGAIG
VGITQPRQAMLSLGTSGVYFAVSDGFSANPESALHSFCHALPATWHTMSVILSAASCLTWVAELTGASSVPEMIAEVEAD
ADLNSEVIFLPYLSGERTPHNNPDAKGVFFGMTHATKRAELAQAVLEGVGFALADGLDALHATGVEPEEISLIGGGAQSA
YWRQMLADIFNKKLAYRVGGDVGPALGAARLARLGLAGQEKLSEVCPVPRLIQTHLPNIGKHAAYALKREKFQKIYVQLK
DIF

Sequences:

>Translated_483_residues
MFIGIDLGTSGVKVILVDQSGLILGTKTVSISVSRPAPLWSEQDPAEWWSATNQAIKALAKDISLSNVSAIGLAGQMHGA
ALLDDNGKVLRPAILWNDGRCAEECLEMEQLVPTSRDITGNIMMPGFTAPKLKWVQKNEPECFAKIAKVLLPKDYLRYCM
TGDFASDMSDAAGTMWLDVAKRDWNAQLLAATGLTRQQMPKLYEGSQITGTLSKELANEWGMPCVPVVAGAGDNAAGAIG
VGITQPRQAMLSLGTSGVYFAVSDGFSANPESALHSFCHALPATWHTMSVILSAASCLTWVAELTGASSVPEMIAEVEAD
ADLNSEVIFLPYLSGERTPHNNPDAKGVFFGMTHATKRAELAQAVLEGVGFALADGLDALHATGVEPEEISLIGGGAQSA
YWRQMLADIFNKKLAYRVGGDVGPALGAARLARLGLAGQEKLSEVCPVPRLIQTHLPNIGKHAAYALKREKFQKIYVQLK
DIF
>Mature_483_residues
MFIGIDLGTSGVKVILVDQSGLILGTKTVSISVSRPAPLWSEQDPAEWWSATNQAIKALAKDISLSNVSAIGLAGQMHGA
ALLDDNGKVLRPAILWNDGRCAEECLEMEQLVPTSRDITGNIMMPGFTAPKLKWVQKNEPECFAKIAKVLLPKDYLRYCM
TGDFASDMSDAAGTMWLDVAKRDWNAQLLAATGLTRQQMPKLYEGSQITGTLSKELANEWGMPCVPVVAGAGDNAAGAIG
VGITQPRQAMLSLGTSGVYFAVSDGFSANPESALHSFCHALPATWHTMSVILSAASCLTWVAELTGASSVPEMIAEVEAD
ADLNSEVIFLPYLSGERTPHNNPDAKGVFFGMTHATKRAELAQAVLEGVGFALADGLDALHATGVEPEEISLIGGGAQSA
YWRQMLADIFNKKLAYRVGGDVGPALGAARLARLGLAGQEKLSEVCPVPRLIQTHLPNIGKHAAYALKREKFQKIYVQLK
DIF

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=438, Percent_Identity=23.972602739726, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI4504007, Length=437, Percent_Identity=24.0274599542334, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI189409120, Length=437, Percent_Identity=24.0274599542334, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI41393575, Length=434, Percent_Identity=22.8110599078341, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI164663828, Length=547, Percent_Identity=22.3034734917733, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI164663830, Length=262, Percent_Identity=25.5725190839695, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1789987, Length=479, Percent_Identity=65.3444676409186, Blast_Score=627, Evalue=0.0,
Organism=Escherichia coli, GI1790005, Length=495, Percent_Identity=27.2727272727273, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI1790361, Length=477, Percent_Identity=24.1090146750524, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789168, Length=420, Percent_Identity=25.7142857142857, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1787789, Length=505, Percent_Identity=22.3762376237624, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1789138, Length=457, Percent_Identity=21.8818380743982, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17535599, Length=449, Percent_Identity=24.2761692650334, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321633, Length=336, Percent_Identity=23.2142857142857, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17864214, Length=431, Percent_Identity=24.3619489559165, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24655555, Length=418, Percent_Identity=24.1626794258373, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24655560, Length=418, Percent_Identity=24.1626794258373, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24655570, Length=418, Percent_Identity=24.1626794258373, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24655574, Length=418, Percent_Identity=24.1626794258373, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24655565, Length=418, Percent_Identity=24.1626794258373, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24654573, Length=381, Percent_Identity=24.1469816272966, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24657106, Length=464, Percent_Identity=22.8448275862069, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24657102, Length=464, Percent_Identity=22.8448275862069, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357867, Length=537, Percent_Identity=19.9255121042831, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356607, Length=297, Percent_Identity=23.2323232323232, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19920476, Length=508, Percent_Identity=22.4409448818898, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 51624; Mature: 51624

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIGIDLGTSGVKVILVDQSGLILGTKTVSISVSRPAPLWSEQDPAEWWSATNQAIKALA
CEEEEEECCCCEEEEEEECCCEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
KDISLSNVSAIGLAGQMHGAALLDDNGKVLRPAILWNDGRCAEECLEMEQLVPTSRDITG
HHCCCCCCHHHEECCCCCCCEEECCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCC
NIMMPGFTAPKLKWVQKNEPECFAKIAKVLLPKDYLRYCMTGDFASDMSDAAGTMWLDVA
CEECCCCCCCCEEECCCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCEEEEEC
KRDWNAQLLAATGLTRQQMPKLYEGSQITGTLSKELANEWGMPCVPVVAGAGDNAAGAIG
CCCCCCEEEEECCCCHHHCHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCEEE
VGITQPRQAMLSLGTSGVYFAVSDGFSANPESALHSFCHALPATWHTMSVILSAASCLTW
CCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VAELTGASSVPEMIAEVEADADLNSEVIFLPYLSGERTPHNNPDAKGVFFGMTHATKRAE
HHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECHHHHHHHH
LAQAVLEGVGFALADGLDALHATGVEPEEISLIGGGAQSAYWRQMLADIFNKKLAYRVGG
HHHHHHHHCCHHHHHCHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHEECCCC
DVGPALGAARLARLGLAGQEKLSEVCPVPRLIQTHLPNIGKHAAYALKREKFQKIYVQLK
CCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
DIF
HCC
>Mature Secondary Structure
MFIGIDLGTSGVKVILVDQSGLILGTKTVSISVSRPAPLWSEQDPAEWWSATNQAIKALA
CEEEEEECCCCEEEEEEECCCEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
KDISLSNVSAIGLAGQMHGAALLDDNGKVLRPAILWNDGRCAEECLEMEQLVPTSRDITG
HHCCCCCCHHHEECCCCCCCEEECCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCC
NIMMPGFTAPKLKWVQKNEPECFAKIAKVLLPKDYLRYCMTGDFASDMSDAAGTMWLDVA
CEECCCCCCCCEEECCCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCEEEEEC
KRDWNAQLLAATGLTRQQMPKLYEGSQITGTLSKELANEWGMPCVPVVAGAGDNAAGAIG
CCCCCCEEEEECCCCHHHCHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCEEE
VGITQPRQAMLSLGTSGVYFAVSDGFSANPESALHSFCHALPATWHTMSVILSAASCLTW
CCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VAELTGASSVPEMIAEVEADADLNSEVIFLPYLSGERTPHNNPDAKGVFFGMTHATKRAE
HHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECHHHHHHHH
LAQAVLEGVGFALADGLDALHATGVEPEEISLIGGGAQSAYWRQMLADIFNKKLAYRVGG
HHHHHHHHCCHHHHHCHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHEECCCC
DVGPALGAARLARLGLAGQEKLSEVCPVPRLIQTHLPNIGKHAAYALKREKFQKIYVQLK
CCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
DIF
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]