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The map label for this gene is yeiG [H]

Identifier: 119899913

GI number: 119899913

Start: 3974733

End: 3975587

Strand: Direct

Name: yeiG [H]

Synonym: azo3624

Alternate gene names: 119899913

Gene position: 3974733-3975587 (Clockwise)

Preceding gene: 119899912

Following gene: 119899915

Centisome position: 90.83

GC content: 69.71

Gene sequence:

>855_bases
ATGAACACACTCGAACAGATCGCTGCCAACCGCAGCTTCGGCGGCTGGCACAAGCGCTTCCGCCACCGCTCGGCCGTGCT
CGGCTGCGACATGGTGTTCGCCGTCTACCTGCCGCCGCAGGCGGAAGACGGCCCGGTGCCAGTGCTGTACTGGCTGTCGG
GGCTGACCTGCACCGACGAGAACTTCATGCAGAAGGCGGGGGCCCAGCGCGTAGCCGCCGAACTCGGCATTGCCATCGTC
GCGCCGGACACCAGCCCGCGCGGCGCCGATGTGCCGGGTGACCCCGACGGCGGATGGGACTTCGGCCACGGCGCCGGCTT
CTATGTGAATGCCAACCAGGCGCCGTGGGACCGCCACTACCGCATGTACGACTACGTGGTGGACGAACTGCCGGCGCTGG
TCGAGGCCCGCTTTCCGGTGACGACCCGGCGTGCGATCAGCGGCCATTCGATGGGGGGCCACGGCGCGCTGATCTGTGCG
CTGAAGAACCCGGGGCGCTACGCCTCGGTTTCCGCCTTCGCACCGATCACCCACCCGGCGGACTGCCCGTGGGGCGAGAA
AGCCTTCTCGCGCTATCTCGGCGACGACCGCGAGACCTGGAAGGCGTGGGACGCCTGCGAACTGATCGCGGCCACGCCCC
CGGACGGCGAACGCCTGCCGCTGATGGTCGACCAGGGCGATGCCGACAGCTTCCTTGCCACCCAGCTGCGCCCGGAACAG
CTGCGCACCGCGTGCACGCTCGCCGGCCAGCCGCTGACGCTGCGCCTGCAGCCGGGCTACGACCACAGCTATTACTTCAT
CGCCAGCTTCATCGACGACCACCTGCGCCACCACGCCGCCGCGCTGCGCCGCTGA

Upstream 100 bases:

>100_bases
AACAAGGCCTTCGACCTGATGCACGAAGGCAAGAGCATCCGCTCGGTCATCATCTACTGATACAGGTAAACGGGCGTCCG
CGCCCGGCACCGCCATCCTC

Downstream 100 bases:

>100_bases
CCGCAGTCAGGGCCCGACGCGGCGCGCGGTAAAGCTGACCGGCGGCATTTCGTCGTAGCCGCCGCGGGTTTCCAGCGTCA
GGCGCAGGCCGCCCGCGTAC

Product: esterase

Products: NA

Alternate protein names: FGH [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MNTLEQIAANRSFGGWHKRFRHRSAVLGCDMVFAVYLPPQAEDGPVPVLYWLSGLTCTDENFMQKAGAQRVAAELGIAIV
APDTSPRGADVPGDPDGGWDFGHGAGFYVNANQAPWDRHYRMYDYVVDELPALVEARFPVTTRRAISGHSMGGHGALICA
LKNPGRYASVSAFAPITHPADCPWGEKAFSRYLGDDRETWKAWDACELIAATPPDGERLPLMVDQGDADSFLATQLRPEQ
LRTACTLAGQPLTLRLQPGYDHSYYFIASFIDDHLRHHAAALRR

Sequences:

>Translated_284_residues
MNTLEQIAANRSFGGWHKRFRHRSAVLGCDMVFAVYLPPQAEDGPVPVLYWLSGLTCTDENFMQKAGAQRVAAELGIAIV
APDTSPRGADVPGDPDGGWDFGHGAGFYVNANQAPWDRHYRMYDYVVDELPALVEARFPVTTRRAISGHSMGGHGALICA
LKNPGRYASVSAFAPITHPADCPWGEKAFSRYLGDDRETWKAWDACELIAATPPDGERLPLMVDQGDADSFLATQLRPEQ
LRTACTLAGQPLTLRLQPGYDHSYYFIASFIDDHLRHHAAALRR
>Mature_284_residues
MNTLEQIAANRSFGGWHKRFRHRSAVLGCDMVFAVYLPPQAEDGPVPVLYWLSGLTCTDENFMQKAGAQRVAAELGIAIV
APDTSPRGADVPGDPDGGWDFGHGAGFYVNANQAPWDRHYRMYDYVVDELPALVEARFPVTTRRAISGHSMGGHGALICA
LKNPGRYASVSAFAPITHPADCPWGEKAFSRYLGDDRETWKAWDACELIAATPPDGERLPLMVDQGDADSFLATQLRPEQ
LRTACTLAGQPLTLRLQPGYDHSYYFIASFIDDHLRHHAAALRR

Specific function: Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate [H]

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the esterase D family [H]

Homologues:

Organism=Homo sapiens, GI33413400, Length=282, Percent_Identity=58.5106382978723, Blast_Score=349, Evalue=2e-96,
Organism=Escherichia coli, GI1788477, Length=281, Percent_Identity=61.2099644128114, Blast_Score=348, Evalue=3e-97,
Organism=Escherichia coli, GI1786551, Length=281, Percent_Identity=51.6014234875445, Blast_Score=305, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI17510185, Length=281, Percent_Identity=48.3985765124555, Blast_Score=276, Evalue=6e-75,
Organism=Saccharomyces cerevisiae, GI6322393, Length=287, Percent_Identity=42.5087108013937, Blast_Score=225, Evalue=7e-60,
Organism=Drosophila melanogaster, GI45551932, Length=287, Percent_Identity=53.6585365853659, Blast_Score=304, Evalue=6e-83,
Organism=Drosophila melanogaster, GI24648347, Length=287, Percent_Identity=53.6585365853659, Blast_Score=303, Evalue=1e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801
- InterPro:   IPR014186 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: =3.1.2.12 [H]

Molecular weight: Translated: 31312; Mature: 31312

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLEQIAANRSFGGWHKRFRHRSAVLGCDMVFAVYLPPQAEDGPVPVLYWLSGLTCTDE
CCHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEECCCCEECCH
NFMQKAGAQRVAAELGIAIVAPDTSPRGADVPGDPDGGWDFGHGAGFYVNANQAPWDRHY
HHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHH
RMYDYVVDELPALVEARFPVTTRRAISGHSMGGHGALICALKNPGRYASVSAFAPITHPA
HHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCC
DCPWGEKAFSRYLGDDRETWKAWDACELIAATPPDGERLPLMVDQGDADSFLATQLRPEQ
CCCCCHHHHHHHHCCCHHHHHHHCCEEEEEECCCCCCCCCEEEECCCCCHHHHHCCCHHH
LRTACTLAGQPLTLRLQPGYDHSYYFIASFIDDHLRHHAAALRR
HHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTLEQIAANRSFGGWHKRFRHRSAVLGCDMVFAVYLPPQAEDGPVPVLYWLSGLTCTDE
CCHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEECCCCEECCH
NFMQKAGAQRVAAELGIAIVAPDTSPRGADVPGDPDGGWDFGHGAGFYVNANQAPWDRHY
HHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHH
RMYDYVVDELPALVEARFPVTTRRAISGHSMGGHGALICALKNPGRYASVSAFAPITHPA
HHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCC
DCPWGEKAFSRYLGDDRETWKAWDACELIAATPPDGERLPLMVDQGDADSFLATQLRPEQ
CCCCCHHHHHHHHCCCHHHHHHHCCEEEEEECCCCCCCCCEEEECCCCCHHHHHCCCHHH
LRTACTLAGQPLTLRLQPGYDHSYYFIASFIDDHLRHHAAALRR
HHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA