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The map label for this gene is yegD [H]

Identifier: 119899915

GI number: 119899915

Start: 3976698

End: 3977960

Strand: Direct

Name: yegD [H]

Synonym: azo3626

Alternate gene names: 119899915

Gene position: 3976698-3977960 (Clockwise)

Preceding gene: 119899913

Following gene: 119899917

Centisome position: 90.87

GC content: 69.36

Gene sequence:

>1263_bases
ATGAACGCCCACCCCGCCCGCGCCTGCGGCATCGACTTCGGCACATCGAACTCCACCGTCGGCTGGTTGCGTCCCGGCCA
GCCCGCGCTGCTGACGCTGGAAGACGGCAAGCCGACGCTGCCCTCGGCGGTGTTCTTCAACGCCGACGAAGACAGCACCT
GCTACGGCCGCGCCGCGCTCGGCGAATACCTCGAAGGCTATGAAGGCCGGTTGATGCGCGCGCTCAAGAGCCTGCTCGGC
AGCAGCCTGATCGACGGCCACACCGAGGTGCACGGCCGCGCGCTGGCCTTCCGCGAACTGCTCGCCCAGTTCATCGGCGA
ACTCAAGAAGCGCGCCGAAGCGCAGGCCGGCCGCAGCTTCGAGCAGGCGGTGTTCGGCCGCCCGGTGCATTTCGTCGACG
ACGACGAGGCCGCCGACCGCCGCGCCCAGGACACGCTGGAAGACATCGCCCGCCGCATCGGCTTCAAGGAAGTGAGCTTC
CAGTTCGAGCCGATCGGCGCCGCGCTGCACTACGAACTGGGGCTTGAGCGCGAAGAACTGGTGCTGATCGCCGACATCGG
CGGCGGCACCGCCGACTTCTCGCTGGTACGGCTGTCGCCGGAACGCGCACGCAACACCGAACGCCACGAAGACCTGCTCG
GCAACGCCGGCGTGCATATCGGCGGTACCGACTTCGACCGCGCACTGAGCCTGGAATGCGTGATGCCGCTGCTCGGCTAC
CGCGGCAAGATGAAGAACGGCGCCGACATTCCGTCCAGCCTGTTCTTCCAGCTCGCCACCTGGCACACCATCAACAGCGC
CTACACCCGCCAGGCCTGGAGCGACCTCCAGAACATCTACCGCGACGCCACCGCGCGCACCGAACTCGACCGCCTCTCGA
GGCTGGTGAACAACCGCGAAGGCCACTGGCTGGCGCTGCAGGTGGAACAGGCGAAGATCGACCTCTCCGCCGCGCCGGTC
GCCCACATGGTGCTCGACCGCCTGGAGCAGGGCCTGCGCCACGACATCGGCGCCGAGGACTTCACCCTCGCCACCCGCAA
CCTGGTCGAACGCGTCGCCGCCACGGTGGATGGCCTGCTGCGCGACGCCGGCGTCGCGCGCGAGCAGGTGGACAGCATCT
ATTTCACCGGCGGCGCCAGCGGCGTGCCGCAACTGCGCGCCCGCATCGCGGCCGAACTGCCGCAGGCGCGCGCGGTGGAA
GGCGATCTCTACGGCAGCATCGGCGCCGGGCTGGCGGTGGAAGCGGCGCGCCGCTACGGCTAA

Upstream 100 bases:

>100_bases
GACGGATACCGGGACCGCTGCTGGAAGCGGGTATCGAGACGCTGGCCCGTGGACGGGCTCTCGCGTAGCATCCCGCACCT
TCCCCCTCGCCCCGCCCCGC

Downstream 100 bases:

>100_bases
GGCAGCGAAGGCGGACGCCCCAACCGGACGCGCAGCGGCCGCACGCCCGACGGTGGATCAGCCGCGGGCAGGAGCCGGCA
CCGCCGCCAGCCCGCCGTCC

Product: chaperon protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MNAHPARACGIDFGTSNSTVGWLRPGQPALLTLEDGKPTLPSAVFFNADEDSTCYGRAALGEYLEGYEGRLMRALKSLLG
SSLIDGHTEVHGRALAFRELLAQFIGELKKRAEAQAGRSFEQAVFGRPVHFVDDDEAADRRAQDTLEDIARRIGFKEVSF
QFEPIGAALHYELGLEREELVLIADIGGGTADFSLVRLSPERARNTERHEDLLGNAGVHIGGTDFDRALSLECVMPLLGY
RGKMKNGADIPSSLFFQLATWHTINSAYTRQAWSDLQNIYRDATARTELDRLSRLVNNREGHWLALQVEQAKIDLSAAPV
AHMVLDRLEQGLRHDIGAEDFTLATRNLVERVAATVDGLLRDAGVAREQVDSIYFTGGASGVPQLRARIAAELPQARAVE
GDLYGSIGAGLAVEAARRYG

Sequences:

>Translated_420_residues
MNAHPARACGIDFGTSNSTVGWLRPGQPALLTLEDGKPTLPSAVFFNADEDSTCYGRAALGEYLEGYEGRLMRALKSLLG
SSLIDGHTEVHGRALAFRELLAQFIGELKKRAEAQAGRSFEQAVFGRPVHFVDDDEAADRRAQDTLEDIARRIGFKEVSF
QFEPIGAALHYELGLEREELVLIADIGGGTADFSLVRLSPERARNTERHEDLLGNAGVHIGGTDFDRALSLECVMPLLGY
RGKMKNGADIPSSLFFQLATWHTINSAYTRQAWSDLQNIYRDATARTELDRLSRLVNNREGHWLALQVEQAKIDLSAAPV
AHMVLDRLEQGLRHDIGAEDFTLATRNLVERVAATVDGLLRDAGVAREQVDSIYFTGGASGVPQLRARIAAELPQARAVE
GDLYGSIGAGLAVEAARRYG
>Mature_420_residues
MNAHPARACGIDFGTSNSTVGWLRPGQPALLTLEDGKPTLPSAVFFNADEDSTCYGRAALGEYLEGYEGRLMRALKSLLG
SSLIDGHTEVHGRALAFRELLAQFIGELKKRAEAQAGRSFEQAVFGRPVHFVDDDEAADRRAQDTLEDIARRIGFKEVSF
QFEPIGAALHYELGLEREELVLIADIGGGTADFSLVRLSPERARNTERHEDLLGNAGVHIGGTDFDRALSLECVMPLLGY
RGKMKNGADIPSSLFFQLATWHTINSAYTRQAWSDLQNIYRDATARTELDRLSRLVNNREGHWLALQVEQAKIDLSAAPV
AHMVLDRLEQGLRHDIGAEDFTLATRNLVERVAATVDGLLRDAGVAREQVDSIYFTGGASGVPQLRARIAAELPQARAVE
GDLYGSIGAGLAVEAARRYG

Specific function: Unknown

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Homo sapiens, GI16507237, Length=407, Percent_Identity=23.5872235872236, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87082035, Length=448, Percent_Identity=30.1339285714286, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1786196, Length=413, Percent_Identity=24.6973365617433, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788875, Length=245, Percent_Identity=30.6122448979592, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17534015, Length=409, Percent_Identity=24.9388753056235, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17534013, Length=409, Percent_Identity=24.9388753056235, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17507981, Length=409, Percent_Identity=24.6943765281174, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17568549, Length=410, Percent_Identity=23.4146341463415, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562024, Length=437, Percent_Identity=23.1121281464531, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322505, Length=432, Percent_Identity=23.3796296296296, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322426, Length=421, Percent_Identity=23.5154394299287, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320805, Length=441, Percent_Identity=23.3560090702948, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319314, Length=449, Percent_Identity=23.3853006681514, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641406, Length=245, Percent_Identity=28.9795918367347, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24641408, Length=245, Percent_Identity=28.9795918367347, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24641402, Length=245, Percent_Identity=28.9795918367347, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24641404, Length=245, Percent_Identity=28.9795918367347, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 45914; Mature: 45914

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS01036 HSP70_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAHPARACGIDFGTSNSTVGWLRPGQPALLTLEDGKPTLPSAVFFNADEDSTCYGRAAL
CCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCEEEEECCCCCCHHHHHHH
GEYLEGYEGRLMRALKSLLGSSLIDGHTEVHGRALAFRELLAQFIGELKKRAEAQAGRSF
HHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
EQAVFGRPVHFVDDDEAADRRAQDTLEDIARRIGFKEVSFQFEPIGAALHYELGLEREEL
HHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCEEEEHHCCCCCCCE
VLIADIGGGTADFSLVRLSPERARNTERHEDLLGNAGVHIGGTDFDRALSLECVMPLLGY
EEEEECCCCCCCEEEEEECHHHHCCCHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHCC
RGKMKNGADIPSSLFFQLATWHTINSAYTRQAWSDLQNIYRDATARTELDRLSRLVNNRE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GHWLALQVEQAKIDLSAAPVAHMVLDRLEQGLRHDIGAEDFTLATRNLVERVAATVDGLL
CCEEEEEEECCEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
RDAGVAREQVDSIYFTGGASGVPQLRARIAAELPQARAVEGDLYGSIGAGLAVEAARRYG
HHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHCCCHHCCCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNAHPARACGIDFGTSNSTVGWLRPGQPALLTLEDGKPTLPSAVFFNADEDSTCYGRAAL
CCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCEEEEECCCCCCHHHHHHH
GEYLEGYEGRLMRALKSLLGSSLIDGHTEVHGRALAFRELLAQFIGELKKRAEAQAGRSF
HHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
EQAVFGRPVHFVDDDEAADRRAQDTLEDIARRIGFKEVSFQFEPIGAALHYELGLEREEL
HHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCEEEEHHCCCCCCCE
VLIADIGGGTADFSLVRLSPERARNTERHEDLLGNAGVHIGGTDFDRALSLECVMPLLGY
EEEEECCCCCCCEEEEEECHHHHCCCHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHCC
RGKMKNGADIPSSLFFQLATWHTINSAYTRQAWSDLQNIYRDATARTELDRLSRLVNNRE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GHWLALQVEQAKIDLSAAPVAHMVLDRLEQGLRHDIGAEDFTLATRNLVERVAATVDGLL
CCEEEEEEECCEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
RDAGVAREQVDSIYFTGGASGVPQLRARIAAELPQARAVEGDLYGSIGAGLAVEAARRYG
HHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHCCCHHCCCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7940673; 7984428 [H]