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The map label for this gene is ompR3 [H]

Identifier: 119899904

GI number: 119899904

Start: 3966875

End: 3967591

Strand: Direct

Name: ompR3 [H]

Synonym: azo3615

Alternate gene names: 119899904

Gene position: 3966875-3967591 (Clockwise)

Preceding gene: 119899902

Following gene: 119899905

Centisome position: 90.65

GC content: 69.32

Gene sequence:

>717_bases
ATGAGCCACCAGATTCTCATTGTCGATGACGACCCGCAGATCCGCAGCCTGCTGGCCGACTACCTCGACAATTTCGGCTT
CGCCTGCCGCGCGGTCGGCGACGCCACCGCAATGCGCGCCGCGCTGGCGGCCCGTCCGGCTGACCTCGTCATCCTCGACC
TGATGCTGCCCGGCGAGGACGGCCTCAGCCTGTGCCGCACGCTGCGCGCCCATGGCGACATCCCGATCATCATGCTCACC
GCGCGGGCGGAGGCGGCGGACCGCATCGTGGGCCTCGAACTCGGTGCCGACGATTACGTGGTCAAGCCCTTCGACCCGCG
CGAACTGGTCGCCCGCATCCACACCATCCTGCGCCGCGCCGCCGCGGCGCGGCAGGCACCGGCTGCCGAGGCGAACGGCG
CGGGCGAAATCGCCTTCGCGGGCTGGCAACTCAATCCGCTCACGCGCGTGCTGACCTCGCCCGAACGCCTCGCCATTCCG
CTCTCCAATGCGGAATTCCGCCTGCTGTGGGTCTTCATCGAGCGGCCGCGGTGCGTGCTCAACCGCGACCAGCTGCTCGA
TGCCGCGCGCGGTCGCGCCGCCGAAGCCTTCGACCGCAGCATCGACCTGCTGGTATCCCGGCTGCGGCAAAAGCTGCAGG
AAGACCCCCGTCTGCCCAAGCTGCTGAAGACGATCCGCGGCGAGGGCTACCTGTTCGATACCGAGGTGGTGCGCTGA

Upstream 100 bases:

>100_bases
CATGACAGGCGCGGCCTGATGTATCCGGATCACTACAAAGCAGACAAGCAGGATACAAGACGATCGCCGACAATTCACCG
TCTTTCGCTTGCCGCCTGTC

Downstream 100 bases:

>100_bases
TGCGGGTACTCCGCCGGCTGCGCCCGCTGCTGCCGGATTCGCTGTTCGGCCGCCTGTTCGGCATGGTGGTGGTGGCGGTG
CTCGCCAGCCACCTGGTCAC

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MSHQILIVDDDPQIRSLLADYLDNFGFACRAVGDATAMRAALAARPADLVILDLMLPGEDGLSLCRTLRAHGDIPIIMLT
ARAEAADRIVGLELGADDYVVKPFDPRELVARIHTILRRAAAARQAPAAEANGAGEIAFAGWQLNPLTRVLTSPERLAIP
LSNAEFRLLWVFIERPRCVLNRDQLLDAARGRAAEAFDRSIDLLVSRLRQKLQEDPRLPKLLKTIRGEGYLFDTEVVR

Sequences:

>Translated_238_residues
MSHQILIVDDDPQIRSLLADYLDNFGFACRAVGDATAMRAALAARPADLVILDLMLPGEDGLSLCRTLRAHGDIPIIMLT
ARAEAADRIVGLELGADDYVVKPFDPRELVARIHTILRRAAAARQAPAAEANGAGEIAFAGWQLNPLTRVLTSPERLAIP
LSNAEFRLLWVFIERPRCVLNRDQLLDAARGRAAEAFDRSIDLLVSRLRQKLQEDPRLPKLLKTIRGEGYLFDTEVVR
>Mature_237_residues
SHQILIVDDDPQIRSLLADYLDNFGFACRAVGDATAMRAALAARPADLVILDLMLPGEDGLSLCRTLRAHGDIPIIMLTA
RAEAADRIVGLELGADDYVVKPFDPRELVARIHTILRRAAAARQAPAAEANGAGEIAFAGWQLNPLTRVLTSPERLAIPL
SNAEFRLLWVFIERPRCVLNRDQLLDAARGRAAEAFDRSIDLLVSRLRQKLQEDPRLPKLLKTIRGEGYLFDTEVVR

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=47.8448275862069, Blast_Score=210, Evalue=5e-56,
Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=38.2978723404255, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=35.3711790393013, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1787229, Length=238, Percent_Identity=39.0756302521008, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1786599, Length=238, Percent_Identity=37.3949579831933, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=37.3913043478261, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI145693140, Length=240, Percent_Identity=35, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=35.3448275862069, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=34.7826086956522, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=37.2294372294372, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=35.3448275862069, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=32.034632034632, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=31.5789473684211, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=32.9004329004329, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1790299, Length=130, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=34.2592592592593, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI145693157, Length=100, Percent_Identity=37, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=32.5, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26338; Mature: 26207

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHQILIVDDDPQIRSLLADYLDNFGFACRAVGDATAMRAALAARPADLVILDLMLPGED
CCCEEEEECCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCC
GLSLCRTLRAHGDIPIIMLTARAEAADRIVGLELGADDYVVKPFDPRELVARIHTILRRA
HHHHHHHHHHCCCCEEEEEECCCCHHHHEEEEEECCCCCEECCCCHHHHHHHHHHHHHHH
AAARQAPAAEANGAGEIAFAGWQLNPLTRVLTSPERLAIPLSNAEFRLLWVFIERPRCVL
HHHHCCCCCCCCCCCCEEEECCCCCHHHHHHCCCCCEEEEECCCCEEEEEEEEECCHHHC
NRDQLLDAARGRAAEAFDRSIDLLVSRLRQKLQEDPRLPKLLKTIRGEGYLFDTEVVR
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEECHHHCC
>Mature Secondary Structure 
SHQILIVDDDPQIRSLLADYLDNFGFACRAVGDATAMRAALAARPADLVILDLMLPGED
CCEEEEECCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCC
GLSLCRTLRAHGDIPIIMLTARAEAADRIVGLELGADDYVVKPFDPRELVARIHTILRRA
HHHHHHHHHHCCCCEEEEEECCCCHHHHEEEEEECCCCCEECCCCHHHHHHHHHHHHHHH
AAARQAPAAEANGAGEIAFAGWQLNPLTRVLTSPERLAIPLSNAEFRLLWVFIERPRCVL
HHHHCCCCCCCCCCCCEEEECCCCCHHHHHHCCCCCEEEEECCCCEEEEEEEEECCHHHC
NRDQLLDAARGRAAEAFDRSIDLLVSRLRQKLQEDPRLPKLLKTIRGEGYLFDTEVVR
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEECHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]