Click here to switch to the map view.

The map label for this gene is dapD [H]

Identifier: 119898296

GI number: 119898296

Start: 2211431

End: 2212252

Strand: Direct

Name: dapD [H]

Synonym: azo2005

Alternate gene names: 119898296

Gene position: 2211431-2212252 (Clockwise)

Preceding gene: 119898295

Following gene: 119898297

Centisome position: 50.53

GC content: 65.82

Gene sequence:

>822_bases
ATGCAAGACCTGCAAAAGATCATCGACGACGCCTTCGAGAACCGCGCCTCCCTGTCCCCCGCTGCGGCGCCCGCCGCCGT
GCGCGATGCGGTGGCCGAAGTGATTGCCGGGCTGGATGCCGGCACGTTGCGCGTCGCCGAGAAGAAGGACGGCCAGTGGG
TGGTCAACCAGTGGATCAAGAAGGCGGTGCTGATCTCCTTCCGCCTGCGCGACAACGAAGTGATTCCGGCCGGTGGCCTG
AATTTCTTCGACAAGGTGCCGACCAAGTTCGGCGACTACACGCCGGAGCAGTTCCAGCAGGGCGGCTTCCGCGTGGTGCC
GCCGGCGGTCGCGCGCAAGGGCAGTTACATCGCGAAGAACGTGGTACTGATGCCCTCCTATGTGAACATCGGCGCCTACG
TGGATGAAGGCACCATGGTCGACACCTGGGCCACCGTCGGTTCCTGCGCCCAGATCGGCAAGAACGTGCACCTGTCCGGC
GGCGTCGGCATCGGCGGCGTGCTCGAGCCGGTGCAAGCCGGCCCGGTCATCATCGAGGACAACGTCTTCGTCGGCGCGCG
CTCCGAGGTGGTCGAAGGCGTGATCATCGAAGAGAACGCGGTGCTGTCGATGGGCGTGTATATCGGCCAGAGCACCAAGA
TCTACGACCGTGAAACCGGCTCCATCACCTACGGCCGCGTGCCCGCCGGCGCCGTCGTGGTGCCCGGCAGCCTGCCTTCG
GCCGACGGCAAGTACAGCCTGTACTGCGCAGTCATCGTGAAGAAGGTCGACGCCCAGACCCGCGCCAAGACCGGCATCAA
CGAGCTGCTGCGCGGCGCCTGA

Upstream 100 bases:

>100_bases
GCGGGCTTTGTCCGCATCGCGCTGGTGGCCGATACCGCCGAGTGTGTCGAAGCCGCCGAACGCATCATCGCCTTCTGTCA
AAAACACTGAGAGACCCCCA

Downstream 100 bases:

>100_bases
TCCACCGGGGGCGGCGTTGCCGCCCCGCCCTGCCCCTCGCCGTGGCCCGCCCACGGCCCTCAGTCGGAACGGAGTGCGAT
ACCCATGATTTTCGACAAGC

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MQDLQKIIDDAFENRASLSPAAAPAAVRDAVAEVIAGLDAGTLRVAEKKDGQWVVNQWIKKAVLISFRLRDNEVIPAGGL
NFFDKVPTKFGDYTPEQFQQGGFRVVPPAVARKGSYIAKNVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
GVGIGGVLEPVQAGPVIIEDNVFVGARSEVVEGVIIEENAVLSMGVYIGQSTKIYDRETGSITYGRVPAGAVVVPGSLPS
ADGKYSLYCAVIVKKVDAQTRAKTGINELLRGA

Sequences:

>Translated_273_residues
MQDLQKIIDDAFENRASLSPAAAPAAVRDAVAEVIAGLDAGTLRVAEKKDGQWVVNQWIKKAVLISFRLRDNEVIPAGGL
NFFDKVPTKFGDYTPEQFQQGGFRVVPPAVARKGSYIAKNVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
GVGIGGVLEPVQAGPVIIEDNVFVGARSEVVEGVIIEENAVLSMGVYIGQSTKIYDRETGSITYGRVPAGAVVVPGSLPS
ADGKYSLYCAVIVKKVDAQTRAKTGINELLRGA
>Mature_273_residues
MQDLQKIIDDAFENRASLSPAAAPAAVRDAVAEVIAGLDAGTLRVAEKKDGQWVVNQWIKKAVLISFRLRDNEVIPAGGL
NFFDKVPTKFGDYTPEQFQQGGFRVVPPAVARKGSYIAKNVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
GVGIGGVLEPVQAGPVIIEDNVFVGARSEVVEGVIIEENAVLSMGVYIGQSTKIYDRETGSITYGRVPAGAVVVPGSLPS
ADGKYSLYCAVIVKKVDAQTRAKTGINELLRGA

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786362, Length=271, Percent_Identity=74.9077490774908, Blast_Score=403, Evalue=1e-114,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.117 [H]

Molecular weight: Translated: 28925; Mature: 28925

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLQKIIDDAFENRASLSPAAAPAAVRDAVAEVIAGLDAGTLRVAEKKDGQWVVNQWIK
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHH
KAVLISFRLRDNEVIPAGGLNFFDKVPTKFGDYTPEQFQQGGFRVVPPAVARKGSYIAKN
HHHEEEEEECCCEECCCCCCCHHHHCCHHCCCCCHHHHHCCCCEEECHHHHCCCCEEECC
VVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPVQAGPVIIED
EEEECCEEECCEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCCHHCHHCCCCEEEEC
NVFVGARSEVVEGVIIEENAVLSMGVYIGQSTKIYDRETGSITYGRVPAGAVVVPGSLPS
CEEECCHHHHHCCEEEECCCEEEEEEEECCCCEEEECCCCCEEECCCCCCCEEECCCCCC
ADGKYSLYCAVIVKKVDAQTRAKTGINELLRGA
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQDLQKIIDDAFENRASLSPAAAPAAVRDAVAEVIAGLDAGTLRVAEKKDGQWVVNQWIK
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHH
KAVLISFRLRDNEVIPAGGLNFFDKVPTKFGDYTPEQFQQGGFRVVPPAVARKGSYIAKN
HHHEEEEEECCCEECCCCCCCHHHHCCHHCCCCCHHHHHCCCCEEECHHHHCCCCEEECC
VVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPVQAGPVIIED
EEEECCEEECCEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCCHHCHHCCCCEEEEC
NVFVGARSEVVEGVIIEENAVLSMGVYIGQSTKIYDRETGSITYGRVPAGAVVVPGSLPS
CEEECCHHHHHCCEEEECCCEEEEEEEECCCCEEEECCCCCEEECCCCCCCEEECCCCCC
ADGKYSLYCAVIVKKVDAQTRAKTGINELLRGA
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA