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The map label for this gene is dapC [H]

Identifier: 119898295

GI number: 119898295

Start: 2210146

End: 2211420

Strand: Direct

Name: dapC [H]

Synonym: azo2004

Alternate gene names: 119898295

Gene position: 2210146-2211420 (Clockwise)

Preceding gene: 119898290

Following gene: 119898296

Centisome position: 50.51

GC content: 65.88

Gene sequence:

>1275_bases
ATGATAACATCTTCGCCCTTTTCGACCGCCCCGCGCCGTGCCTTCGCCGGCGTAAATTGTTCCAAAGTGAATCCCGACCT
CGACCGTCTGCAGACCTACCCCTTCGAGAAGCTGCGCGAGCTTTTCCGCGGCGTGACGCCGCCCGCGGCGCTGGCCCCGA
TACGCCTTTCGATCGGCGAGCCGCAGCACCCGACGCCCGCCTTCATCAAGGAAGCGCTGGTGTCCAATCTGGACGGCCTG
TCGGTGTATCCGAACACGCCGGGGAGCGACGCGTTGCGGGGCTCCATCGCGAGCTGGCTGCAGCGCCGCTACGGCCTGCC
GGCGTTCAACGCCGCCACCCAGGTGATCCCGGTCAACGGCACCCGCGAGGCGCTGTTCGCGTTTGCACAGTGCGTGGTCG
ATCGCAGCCGCGCGGGCGCCAAGGTGCTGTGTCCCAACCCGTTCTACCAGATCTACGAAGGCGCCGCGCTGCTCGCGGGT
GCCGATCCGATCTTCCTCAACAACCTGCCCGAAAACCGCTTTGGCTCGGACTTCGACAGCGTGCCGGAGCAGGTCTGGCG
CGAGGTGCAGCTGGTCTATGTCTGCTCCCCGGGCAACCCCACCGGGCGCGTGCTGGGGTTCGACGAGTGGAAGCGGCTGT
TCGAACTGTCGGACCGCTACGGCTTCGTCATCGCGGCGGACGAGTGTTATTCCGAGATCTATTTCGACGACGAGGCGCGT
CCGATCGGCGGGCTCGAAGCCGCCCACCGTCTCGGCAGGAGCGACTTCCGCAATGTCGTGATGTTCTCCAGCCTGTCCAA
GCGTTCGAACGTGCCCGGCCTGCGCTCGGGTTTCGTCGCCGGCGACGCGGCGATCCTGAACAAGTTCCTGCTGTATCGAA
CCTACCAGGGCTGCCAGATGAATCCCGCGGTCCAGGCGGCGTCGGTGGCCGCCTGGAACGACGAAGCGCACGTGGCCGAG
AACCGGCGCCTGTACCGCGAGAAGTTCGACCGTGTGACGCCCATGCTCGCGCCCTATCTGTCCGTCGAGCTGCCCGACGC
CGGTTTCTACCTGTGGGCTCGCGTACCGCCCTCGCTGTGCGGCGGGTCCGATACCGTCTTCGCCCGCGATCTGCTCGACC
AATATAATGTGACCGTTCTGCCCGGCAGCTTCCTCGCCCGCGAAAGCGGTGGCGTCAATCCGGGCGCGGGCTTTGTCCGC
ATCGCGCTGGTGGCCGATACCGCCGAGTGTGTCGAAGCCGCCGAACGCATCATCGCCTTCTGTCAAAAACACTGA

Upstream 100 bases:

>100_bases
ACGACGCTGGAACGGTGGCGAAGATCGGGCGGTACGTCGTTGGCTGCGAGTGCCGAGTCAGTTGGGATACAGGCCTCAGG
CCACGCCTGAAAGGCGCGCC

Downstream 100 bases:

>100_bases
GAGACCCCCAATGCAAGACCTGCAAAAGATCATCGACGACGCCTTCGAGAACCGCGCCTCCCTGTCCCCCGCTGCGGCGC
CCGCCGCCGTGCGCGATGCG

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MITSSPFSTAPRRAFAGVNCSKVNPDLDRLQTYPFEKLRELFRGVTPPAALAPIRLSIGEPQHPTPAFIKEALVSNLDGL
SVYPNTPGSDALRGSIASWLQRRYGLPAFNAATQVIPVNGTREALFAFAQCVVDRSRAGAKVLCPNPFYQIYEGAALLAG
ADPIFLNNLPENRFGSDFDSVPEQVWREVQLVYVCSPGNPTGRVLGFDEWKRLFELSDRYGFVIAADECYSEIYFDDEAR
PIGGLEAAHRLGRSDFRNVVMFSSLSKRSNVPGLRSGFVAGDAAILNKFLLYRTYQGCQMNPAVQAASVAAWNDEAHVAE
NRRLYREKFDRVTPMLAPYLSVELPDAGFYLWARVPPSLCGGSDTVFARDLLDQYNVTVLPGSFLARESGGVNPGAGFVR
IALVADTAECVEAAERIIAFCQKH

Sequences:

>Translated_424_residues
MITSSPFSTAPRRAFAGVNCSKVNPDLDRLQTYPFEKLRELFRGVTPPAALAPIRLSIGEPQHPTPAFIKEALVSNLDGL
SVYPNTPGSDALRGSIASWLQRRYGLPAFNAATQVIPVNGTREALFAFAQCVVDRSRAGAKVLCPNPFYQIYEGAALLAG
ADPIFLNNLPENRFGSDFDSVPEQVWREVQLVYVCSPGNPTGRVLGFDEWKRLFELSDRYGFVIAADECYSEIYFDDEAR
PIGGLEAAHRLGRSDFRNVVMFSSLSKRSNVPGLRSGFVAGDAAILNKFLLYRTYQGCQMNPAVQAASVAAWNDEAHVAE
NRRLYREKFDRVTPMLAPYLSVELPDAGFYLWARVPPSLCGGSDTVFARDLLDQYNVTVLPGSFLARESGGVNPGAGFVR
IALVADTAECVEAAERIIAFCQKH
>Mature_424_residues
MITSSPFSTAPRRAFAGVNCSKVNPDLDRLQTYPFEKLRELFRGVTPPAALAPIRLSIGEPQHPTPAFIKEALVSNLDGL
SVYPNTPGSDALRGSIASWLQRRYGLPAFNAATQVIPVNGTREALFAFAQCVVDRSRAGAKVLCPNPFYQIYEGAALLAG
ADPIFLNNLPENRFGSDFDSVPEQVWREVQLVYVCSPGNPTGRVLGFDEWKRLFELSDRYGFVIAADECYSEIYFDDEAR
PIGGLEAAHRLGRSDFRNVVMFSSLSKRSNVPGLRSGFVAGDAAILNKFLLYRTYQGCQMNPAVQAASVAAWNDEAHVAE
NRRLYREKFDRVTPMLAPYLSVELPDAGFYLWARVPPSLCGGSDTVFARDLLDQYNVTVLPGSFLARESGGVNPGAGFVR
IALVADTAECVEAAERIIAFCQKH

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=441, Percent_Identity=22.2222222222222, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1788722, Length=404, Percent_Identity=27.7227722772277, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786816, Length=367, Percent_Identity=23.9782016348774, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 46578; Mature: 46578

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITSSPFSTAPRRAFAGVNCSKVNPDLDRLQTYPFEKLRELFRGVTPPAALAPIRLSIGE
CCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHCCCCCCCHHCCEEEECCC
PQHPTPAFIKEALVSNLDGLSVYPNTPGSDALRGSIASWLQRRYGLPAFNAATQVIPVNG
CCCCCHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCC
TREALFAFAQCVVDRSRAGAKVLCPNPFYQIYEGAALLAGADPIFLNNLPENRFGSDFDS
CHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHCCCEEEECCCCCEECCCCCCCCCCCHHH
VPEQVWREVQLVYVCSPGNPTGRVLGFDEWKRLFELSDRYGFVIAADECYSEIYFDDEAR
HHHHHHHCEEEEEEECCCCCCCCEECHHHHHHHHHHHCCCCEEEECHHHHHHHEECCCCC
PIGGLEAAHRLGRSDFRNVVMFSSLSKRSNVPGLRSGFVAGDAAILNKFLLYRTYQGCQM
CCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCC
NPAVQAASVAAWNDEAHVAENRRLYREKFDRVTPMLAPYLSVELPDAGFYLWARVPPSLC
CHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCHHHC
GGSDTVFARDLLDQYNVTVLPGSFLARESGGVNPGAGFVRIALVADTAECVEAAERIIAF
CCCCHHHHHHHHHHCCEEEECCHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHH
CQKH
HHCC
>Mature Secondary Structure
MITSSPFSTAPRRAFAGVNCSKVNPDLDRLQTYPFEKLRELFRGVTPPAALAPIRLSIGE
CCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHCCCCCCCHHCCEEEECCC
PQHPTPAFIKEALVSNLDGLSVYPNTPGSDALRGSIASWLQRRYGLPAFNAATQVIPVNG
CCCCCHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCC
TREALFAFAQCVVDRSRAGAKVLCPNPFYQIYEGAALLAGADPIFLNNLPENRFGSDFDS
CHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHCCCEEEECCCCCEECCCCCCCCCCCHHH
VPEQVWREVQLVYVCSPGNPTGRVLGFDEWKRLFELSDRYGFVIAADECYSEIYFDDEAR
HHHHHHHCEEEEEEECCCCCCCCEECHHHHHHHHHHHCCCCEEEECHHHHHHHEECCCCC
PIGGLEAAHRLGRSDFRNVVMFSSLSKRSNVPGLRSGFVAGDAAILNKFLLYRTYQGCQM
CCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCC
NPAVQAASVAAWNDEAHVAENRRLYREKFDRVTPMLAPYLSVELPDAGFYLWARVPPSLC
CHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCHHHC
GGSDTVFARDLLDQYNVTVLPGSFLARESGGVNPGAGFVRIALVADTAECVEAAERIIAF
CCCCHHHHHHHHHHCCEEEECCHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHH
CQKH
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA