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The map label for this gene is map [H]

Identifier: 119898201

GI number: 119898201

Start: 2093581

End: 2094399

Strand: Direct

Name: map [H]

Synonym: azo1910

Alternate gene names: 119898201

Gene position: 2093581-2094399 (Clockwise)

Preceding gene: 119898183

Following gene: 119898202

Centisome position: 47.84

GC content: 64.1

Gene sequence:

>819_bases
ATGAGCATTACCCTCAAGACCGCAGAAGAAATCGAAAAGATGCGGCTGGCCTGCCGCCTGGCTGCCGAAGTGCTCGACCA
CGTCGAGCCCTACGTGAAACCCGGCGTGACCACGGCCGAACTGGACAGGATCTGCCATGAGTACATGGTGAACGTCCAGC
ACACGGTACCCGCCCCCCTCAACTACGCGCCGCCGGGTTACACGCCCTACCCCAAGTCGATCTGCACCTCGGTGAACCAC
CAGGTCTGCCATGGTATTCCCGGCGACAAGGCGCTCAAGAAAGGCGACATCGTCAACCTCGACATCACCGTCATCACCGA
AGACGGTTTTCACGGCGATACCAGCCGGATGTTCATCGTCGGCGGTGACGGCGCCATCCTTGCCAAGCGCCTGTGCCAGG
TGACGTTCGAATGCCTGTGGCTGGGCATCGCCGCGGTGCGCCCGGGCGCGAGGCTCGGCGACATCGGCGCGGTCATCCAG
AAGCACGCCGAGGGCAATGGTTTTTCGGTGGTGCGCGAATTCTGCGGTCACGGCATCGGACGCAAGTTCCACGAGGAGCC
GCAGGTGCTGCACTACGGCAAGGCCGGCACCGGCGTGGAACTGAAGCCCGGCATGATCTTCACGATCGAGCCGATGATCA
ATGCCGGCAAAGCGGCGATTTCCGAACTGCCCGACGGCTGGACCATCGTGACCAAGGACCGCAGCCTGTCGGCGCAGTGG
GAGCACACCATTCTGGTGACCGAGACGGGCGTGGAGGTGCTGACCCTGTCGGCCAAGTGCCCGCCGCCCCCGCCCCTGGT
CGCGGCGTCGTTTGCCTGA

Upstream 100 bases:

>100_bases
GTTAGCACGCGCGGGTTAAGCCGCTCAAGGCGGCCGGCCGCTGCGTTTGCCCGAACACTGCCCATGCGCTAGCCTTGTGA
CCTTTTGAGCCCCCACCCCG

Downstream 100 bases:

>100_bases
CTTGCCGCCGGGTTCCGCGATGAACGACATGGTGATCTCCATCGACGCGCTGCAGGGCGCGATCGGCGAGGCGCGGCGCG
AGCTGGCTGAGGGCAACGCC

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MSITLKTAEEIEKMRLACRLAAEVLDHVEPYVKPGVTTAELDRICHEYMVNVQHTVPAPLNYAPPGYTPYPKSICTSVNH
QVCHGIPGDKALKKGDIVNLDITVITEDGFHGDTSRMFIVGGDGAILAKRLCQVTFECLWLGIAAVRPGARLGDIGAVIQ
KHAEGNGFSVVREFCGHGIGRKFHEEPQVLHYGKAGTGVELKPGMIFTIEPMINAGKAAISELPDGWTIVTKDRSLSAQW
EHTILVTETGVEVLTLSAKCPPPPPLVAASFA

Sequences:

>Translated_272_residues
MSITLKTAEEIEKMRLACRLAAEVLDHVEPYVKPGVTTAELDRICHEYMVNVQHTVPAPLNYAPPGYTPYPKSICTSVNH
QVCHGIPGDKALKKGDIVNLDITVITEDGFHGDTSRMFIVGGDGAILAKRLCQVTFECLWLGIAAVRPGARLGDIGAVIQ
KHAEGNGFSVVREFCGHGIGRKFHEEPQVLHYGKAGTGVELKPGMIFTIEPMINAGKAAISELPDGWTIVTKDRSLSAQW
EHTILVTETGVEVLTLSAKCPPPPPLVAASFA
>Mature_271_residues
SITLKTAEEIEKMRLACRLAAEVLDHVEPYVKPGVTTAELDRICHEYMVNVQHTVPAPLNYAPPGYTPYPKSICTSVNHQ
VCHGIPGDKALKKGDIVNLDITVITEDGFHGDTSRMFIVGGDGAILAKRLCQVTFECLWLGIAAVRPGARLGDIGAVIQK
HAEGNGFSVVREFCGHGIGRKFHEEPQVLHYGKAGTGVELKPGMIFTIEPMINAGKAAISELPDGWTIVTKDRSLSAQWE
HTILVTETGVEVLTLSAKCPPPPPLVAASFA

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=256, Percent_Identity=51.171875, Blast_Score=248, Evalue=6e-66,
Organism=Homo sapiens, GI40385867, Length=254, Percent_Identity=40.9448818897638, Blast_Score=190, Evalue=1e-48,
Organism=Escherichia coli, GI1786364, Length=257, Percent_Identity=64.9805447470817, Blast_Score=335, Evalue=2e-93,
Organism=Escherichia coli, GI1788728, Length=217, Percent_Identity=27.1889400921659, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71996291, Length=253, Percent_Identity=49.0118577075099, Blast_Score=238, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6323273, Length=264, Percent_Identity=45.4545454545455, Blast_Score=229, Evalue=4e-61,
Organism=Drosophila melanogaster, GI21355531, Length=253, Percent_Identity=49.0118577075099, Blast_Score=220, Evalue=6e-58,
Organism=Drosophila melanogaster, GI24583427, Length=254, Percent_Identity=42.1259842519685, Blast_Score=196, Evalue=1e-50,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29356; Mature: 29225

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITLKTAEEIEKMRLACRLAAEVLDHVEPYVKPGVTTAELDRICHEYMVNVQHTVPAPL
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCC
NYAPPGYTPYPKSICTSVNHQVCHGIPGDKALKKGDIVNLDITVITEDGFHGDTSRMFIV
CCCCCCCCCCCHHHHHHCCHHHHCCCCCCHHHCCCCEEEEEEEEEECCCCCCCCCEEEEE
GGDGAILAKRLCQVTFECLWLGIAAVRPGARLGDIGAVIQKHAEGNGFSVVREFCGHGIG
ECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
RKFHEEPQVLHYGKAGTGVELKPGMIFTIEPMINAGKAAISELPDGWTIVTKDRSLSAQW
CHHCCCCCEEEECCCCCCCEECCCEEEEECCCCCCHHHHHHHCCCCCEEEEECCCCCCCC
EHTILVTETGVEVLTLSAKCPPPPPLVAASFA
CEEEEEEECCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
SITLKTAEEIEKMRLACRLAAEVLDHVEPYVKPGVTTAELDRICHEYMVNVQHTVPAPL
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCC
NYAPPGYTPYPKSICTSVNHQVCHGIPGDKALKKGDIVNLDITVITEDGFHGDTSRMFIV
CCCCCCCCCCCHHHHHHCCHHHHCCCCCCHHHCCCCEEEEEEEEEECCCCCCCCCEEEEE
GGDGAILAKRLCQVTFECLWLGIAAVRPGARLGDIGAVIQKHAEGNGFSVVREFCGHGIG
ECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
RKFHEEPQVLHYGKAGTGVELKPGMIFTIEPMINAGKAAISELPDGWTIVTKDRSLSAQW
CHHCCCCCEEEECCCCCCCEECCCEEEEECCCCCCHHHHHHHCCCCCEEEEECCCCCCCC
EHTILVTETGVEVLTLSAKCPPPPPLVAASFA
CEEEEEEECCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]