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The map label for this gene is bioD [H]

Identifier: 119898183

GI number: 119898183

Start: 2077190

End: 2077876

Strand: Direct

Name: bioD [H]

Synonym: azo1892

Alternate gene names: 119898183

Gene position: 2077190-2077876 (Clockwise)

Preceding gene: 119898182

Following gene: 119898201

Centisome position: 47.47

GC content: 69.58

Gene sequence:

>687_bases
ATGACTGCTTCCGCTCACGCCAACGCCTGGTTCGTTACCGGCACCGATACCGAAGTCGGCAAGACCTTCGCCACCTGTGC
GCTGATCCACGCCGCCCGTGCAAAGGGCTTGCGCACCGTGGGGATGAAGCCGGTTGCCGCCGGCGCGGAGCGGGTGGCCG
GTGAATGGGTGAATGAGGACGCCGCGCGCCTGCGTGCGGCGGGCAGCTTCGACCCCGGCCTCGCGCTGCTCAATCCCTAC
TGCCTGCGCAGCCCGGTCGCGCCGCACATCGCTGCGGCCGAGGAAGGCGTGACCTTGAATCCCGCGGTGATGATCGACGC
CTTTGCGCAGCTTCGCGCGCTCGCGGACTGTGTGTTCGTCGAAGGCGTGGGCGGCTTTCGCGTGCCGCTCGCGCAGGGTT
ACGACACGGCCGACCTCGCGGTGCAGCTCGGGTTGCCGGTGATCCTGGTGGTCGGTCTGCGCCTGGGCTGCATCAACCAT
GCCCTGCTGACGGTCGAAGCGATCGCCGCGCGCGGCTTGCCGCTGGCCGGATGGATCGCCAACGAGATTGCACCGGAGAT
GCTGCGCAGGGATGAAAACCTTGCCGCGCTGCGAGCCGGGATCACCGCGCCACTGCTCGGCGTGCTGCCTCACCAGCCGG
ATCGCGATGCGGCGGCGGTTGCCGGCCGGCTGGTGCTGCCGGGCTGA

Upstream 100 bases:

>100_bases
GCGCGTGGCGGCGGCTGGAGCACGCCTACGAGGCCTACCGCGACGCCGACGGCCGCCTGCCCGCCACCTACGATCTCATC
CTGCTCGCGCTGTTCCGCCC

Downstream 100 bases:

>100_bases
GGATTCAGCCTCGCGCAGCGCGCTGGCGGCGCTGTTCGAACAGGCACACCGCGGCCGCCGCCGCGACGTTGAGGGATTCG
ATCCCCGCCGCCATCGGAAT

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MTASAHANAWFVTGTDTEVGKTFATCALIHAARAKGLRTVGMKPVAAGAERVAGEWVNEDAARLRAAGSFDPGLALLNPY
CLRSPVAPHIAAAEEGVTLNPAVMIDAFAQLRALADCVFVEGVGGFRVPLAQGYDTADLAVQLGLPVILVVGLRLGCINH
ALLTVEAIAARGLPLAGWIANEIAPEMLRRDENLAALRAGITAPLLGVLPHQPDRDAAAVAGRLVLPG

Sequences:

>Translated_228_residues
MTASAHANAWFVTGTDTEVGKTFATCALIHAARAKGLRTVGMKPVAAGAERVAGEWVNEDAARLRAAGSFDPGLALLNPY
CLRSPVAPHIAAAEEGVTLNPAVMIDAFAQLRALADCVFVEGVGGFRVPLAQGYDTADLAVQLGLPVILVVGLRLGCINH
ALLTVEAIAARGLPLAGWIANEIAPEMLRRDENLAALRAGITAPLLGVLPHQPDRDAAAVAGRLVLPG
>Mature_227_residues
TASAHANAWFVTGTDTEVGKTFATCALIHAARAKGLRTVGMKPVAAGAERVAGEWVNEDAARLRAAGSFDPGLALLNPYC
LRSPVAPHIAAAEEGVTLNPAVMIDAFAQLRALADCVFVEGVGGFRVPLAQGYDTADLAVQLGLPVILVVGLRLGCINHA
LLTVEAIAARGLPLAGWIANEIAPEMLRRDENLAALRAGITAPLLGVLPHQPDRDAAAVAGRLVLPG

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=216, Percent_Identity=46.2962962962963, Blast_Score=189, Evalue=1e-49,
Organism=Escherichia coli, GI87081944, Length=204, Percent_Identity=37.7450980392157, Blast_Score=132, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324385, Length=172, Percent_Identity=33.7209302325581, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 23588; Mature: 23456

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASAHANAWFVTGTDTEVGKTFATCALIHAARAKGLRTVGMKPVAAGAERVAGEWVNED
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCHH
AARLRAAGSFDPGLALLNPYCLRSPVAPHIAAAEEGVTLNPAVMIDAFAQLRALADCVFV
HHHHHHCCCCCCCHHHHCHHHHCCCCCCCHHHCCCCCEECHHHHHHHHHHHHHHHHHHHE
EGVGGFRVPLAQGYDTADLAVQLGLPVILVVGLRLGCINHALLTVEAIAARGLPLAGWIA
ECCCCEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
NEIAPEMLRRDENLAALRAGITAPLLGVLPHQPDRDAAAVAGRLVLPG
HHHHHHHHHCCCCHHHHHHCCHHHHHHHCCCCCCCCHHHHHCEEECCC
>Mature Secondary Structure 
TASAHANAWFVTGTDTEVGKTFATCALIHAARAKGLRTVGMKPVAAGAERVAGEWVNED
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCHH
AARLRAAGSFDPGLALLNPYCLRSPVAPHIAAAEEGVTLNPAVMIDAFAQLRALADCVFV
HHHHHHCCCCCCCHHHHCHHHHCCCCCCCHHHCCCCCEECHHHHHHHHHHHHHHHHHHHE
EGVGGFRVPLAQGYDTADLAVQLGLPVILVVGLRLGCINHALLTVEAIAARGLPLAGWIA
ECCCCEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
NEIAPEMLRRDENLAALRAGITAPLLGVLPHQPDRDAAAVAGRLVLPG
HHHHHHHHHCCCCHHHHHHCCHHHHHHHCCCCCCCCHHHHHCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA