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The map label for this gene is yaeL [C]

Identifier: 119898193

GI number: 119898193

Start: 2086001

End: 2087365

Strand: Reverse

Name: yaeL [C]

Synonym: azo1902

Alternate gene names: 119898193

Gene position: 2087365-2086001 (Counterclockwise)

Preceding gene: 119898194

Following gene: 119898192

Centisome position: 47.7

GC content: 65.79

Gene sequence:

>1365_bases
ATGAATCTTCTCGATTACCTGATTCCGTTTGCGTTCGCACTCGGTCTGCTGATCCTCGTTCACGAACTCGGCCACTACCT
GGTGGCGCGACGCTGCGGCGTGAAGGTATTGCGCTTTTCGATCGGCTTCGGCAAGCCGCTGATCAAATGGCGCGCCGGAC
GCGACGGCACCGAATGGGCGCTCGGCGCGTTTCCGCTCGGCGGCTACGTCAAGATGCTGGATGAACGCGAAGGGGAGGTG
GCACCTGCCGAGTTGCACCGGGCCTTCAACCGCCAGCCGGTCGGCCGCCGGTTTGCAATCGTCGCCGCGGGGCCGCTCGC
CAATTTCGCGCTCGCCATCCTGCTCTACTGGGCCATCTTCGTCGCCGGCACCGATGAACTGCGCCCCCGTCTCGCCCTCA
CCGAGGTGAATACCCCCGCAGCGGCCGCCGGAATCATGGAAGGCGATCTCGTGCTGTCGGTGGATGACGAGGCGGTCCGC
AGCTGGCAGGAGCTGCGCTGGGCGCTGTTACGCCACGCGCTCGACAACCGACGCATCGTCCTCGCGGTCCGCACGATCGA
CGACCTCACCACCACCCGCGCGCTGGATCTTTCCGGCATCGCAGTCGACGACGGCAAGACCGACCTCATCGCCCGCATCG
GGCTCAAGCCCTGGCGGCCCCCGGTGCCCGCGGTGCTGGGCAAAGTAGCCCCGGAAGGCGCGGCCGCGCGCGCGGGACTG
CTGAGCGGCGACGAAGTCATCGCGGTGGACGCGCGGGCCGTGGCCGAGTGGTCGGACATGGTTTCCGCGGTACGCGCTTC
GCCGGGCAAGCCGCTGTCCTTCACCGTGCGCCGCGACGGCCGCAACCTGACCCTGGAGGTGACGCCCGACGCCGCTACCG
ACAATGGCGAGCAGATCGGCCGCATCGGCGTCGCGGTGGCTGAACCGCTCGTGGGCGGCGCCTCGATGTTCGCCAAGGTG
AGCTACGGCCCCTTCGAAGGATTCGCGAAGGCTGTCCGCCAGACCTGGGAAACCAGCGTGCTGAGCCTGCAGATGATGGG
CCGCATGCTGACGGGCGAGGTATCGTGGAAGAACCTTTCCGGCCCGGTCACGATCGCCGATTACGCCGGCCAGACCGCAC
AGCTCGGCCTCAGCCACTACCTGAAGTTCGTGGCCCTCATCAGCATCAGCCTGGGGGTGCTGAACCTGCTGCCCATCCCG
GTGCTGGATGGCGGGCATTTACTGTATTATCTGGTCGAAATCGTCAAAGGCGGCCCGATTCCGGAACGCATCATGGAGAT
CGGTCAACAAATCGGTCTCGTCCTCCTCGCAATGCTCATGGCATTCGCCTTCTACAACGACATAACCCGTCTCATTTCCG
GCTAG

Upstream 100 bases:

>100_bases
CGGGGCAACATGCGGTCGATTCGGTCGAAGCCGTGCTTGACGCGGATCGCCACGCCCGCCGGATCGCGCGGGAAGAAATA
CAGACCCGCCGGATCCCCTG

Downstream 100 bases:

>100_bases
TGACCCGCATGAAACACAAGCTTCTCTCAGGGCTCGTGATGGCCCTCTTTGCCGCTGCGCCGGCATTCGCCTTCGATCCC
TTCGTGGTCAAGGACATCCG

Product: membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MNLLDYLIPFAFALGLLILVHELGHYLVARRCGVKVLRFSIGFGKPLIKWRAGRDGTEWALGAFPLGGYVKMLDEREGEV
APAELHRAFNRQPVGRRFAIVAAGPLANFALAILLYWAIFVAGTDELRPRLALTEVNTPAAAAGIMEGDLVLSVDDEAVR
SWQELRWALLRHALDNRRIVLAVRTIDDLTTTRALDLSGIAVDDGKTDLIARIGLKPWRPPVPAVLGKVAPEGAAARAGL
LSGDEVIAVDARAVAEWSDMVSAVRASPGKPLSFTVRRDGRNLTLEVTPDAATDNGEQIGRIGVAVAEPLVGGASMFAKV
SYGPFEGFAKAVRQTWETSVLSLQMMGRMLTGEVSWKNLSGPVTIADYAGQTAQLGLSHYLKFVALISISLGVLNLLPIP
VLDGGHLLYYLVEIVKGGPIPERIMEIGQQIGLVLLAMLMAFAFYNDITRLISG

Sequences:

>Translated_454_residues
MNLLDYLIPFAFALGLLILVHELGHYLVARRCGVKVLRFSIGFGKPLIKWRAGRDGTEWALGAFPLGGYVKMLDEREGEV
APAELHRAFNRQPVGRRFAIVAAGPLANFALAILLYWAIFVAGTDELRPRLALTEVNTPAAAAGIMEGDLVLSVDDEAVR
SWQELRWALLRHALDNRRIVLAVRTIDDLTTTRALDLSGIAVDDGKTDLIARIGLKPWRPPVPAVLGKVAPEGAAARAGL
LSGDEVIAVDARAVAEWSDMVSAVRASPGKPLSFTVRRDGRNLTLEVTPDAATDNGEQIGRIGVAVAEPLVGGASMFAKV
SYGPFEGFAKAVRQTWETSVLSLQMMGRMLTGEVSWKNLSGPVTIADYAGQTAQLGLSHYLKFVALISISLGVLNLLPIP
VLDGGHLLYYLVEIVKGGPIPERIMEIGQQIGLVLLAMLMAFAFYNDITRLISG
>Mature_454_residues
MNLLDYLIPFAFALGLLILVHELGHYLVARRCGVKVLRFSIGFGKPLIKWRAGRDGTEWALGAFPLGGYVKMLDEREGEV
APAELHRAFNRQPVGRRFAIVAAGPLANFALAILLYWAIFVAGTDELRPRLALTEVNTPAAAAGIMEGDLVLSVDDEAVR
SWQELRWALLRHALDNRRIVLAVRTIDDLTTTRALDLSGIAVDDGKTDLIARIGLKPWRPPVPAVLGKVAPEGAAARAGL
LSGDEVIAVDARAVAEWSDMVSAVRASPGKPLSFTVRRDGRNLTLEVTPDAATDNGEQIGRIGVAVAEPLVGGASMFAKV
SYGPFEGFAKAVRQTWETSVLSLQMMGRMLTGEVSWKNLSGPVTIADYAGQTAQLGLSHYLKFVALISISLGVLNLLPIP
VLDGGHLLYYLVEIVKGGPIPERIMEIGQQIGLVLLAMLMAFAFYNDITRLISG

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=453, Percent_Identity=43.046357615894, Blast_Score=352, Evalue=3e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49019; Mature: 49019

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLDYLIPFAFALGLLILVHELGHYLVARRCGVKVLRFSIGFGKPLIKWRAGRDGTEWA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHEEECCCCCCCCE
LGAFPLGGYVKMLDEREGEVAPAELHRAFNRQPVGRRFAIVAAGPLANFALAILLYWAIF
EECCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHH
VAGTDELRPRLALTEVNTPAAAAGIMEGDLVLSVDDEAVRSWQELRWALLRHALDNRRIV
HCCCHHHCCCEEEEECCCCHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCEEE
LAVRTIDDLTTTRALDLSGIAVDDGKTDLIARIGLKPWRPPVPAVLGKVAPEGAAARAGL
EEEEEHHHHHHHHEECCCCEEECCCCHHHHHHCCCCCCCCCHHHHHHCCCCCCCHHHCCC
LSGDEVIAVDARAVAEWSDMVSAVRASPGKPLSFTVRRDGRNLTLEVTPDAATDNGEQIG
CCCCCEEEECHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCCCCCCHHHH
RIGVAVAEPLVGGASMFAKVSYGPFEGFAKAVRQTWETSVLSLQMMGRMLTGEVSWKNLS
HHHHHHHHHHCCCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GPVTIADYAGQTAQLGLSHYLKFVALISISLGVLNLLPIPVLDGGHLLYYLVEIVKGGPI
CCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCC
PERIMEIGQQIGLVLLAMLMAFAFYNDITRLISG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLLDYLIPFAFALGLLILVHELGHYLVARRCGVKVLRFSIGFGKPLIKWRAGRDGTEWA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHEEECCCCCCCCE
LGAFPLGGYVKMLDEREGEVAPAELHRAFNRQPVGRRFAIVAAGPLANFALAILLYWAIF
EECCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHH
VAGTDELRPRLALTEVNTPAAAAGIMEGDLVLSVDDEAVRSWQELRWALLRHALDNRRIV
HCCCHHHCCCEEEEECCCCHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCEEE
LAVRTIDDLTTTRALDLSGIAVDDGKTDLIARIGLKPWRPPVPAVLGKVAPEGAAARAGL
EEEEEHHHHHHHHEECCCCEEECCCCHHHHHHCCCCCCCCCHHHHHHCCCCCCCHHHCCC
LSGDEVIAVDARAVAEWSDMVSAVRASPGKPLSFTVRRDGRNLTLEVTPDAATDNGEQIG
CCCCCEEEECHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCCCCCCHHHH
RIGVAVAEPLVGGASMFAKVSYGPFEGFAKAVRQTWETSVLSLQMMGRMLTGEVSWKNLS
HHHHHHHHHHCCCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GPVTIADYAGQTAQLGLSHYLKFVALISISLGVLNLLPIPVLDGGHLLYYLVEIVKGGPI
CCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCC
PERIMEIGQQIGLVLLAMLMAFAFYNDITRLISG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]