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The map label for this gene is mucD3 [H]

Identifier: 119898054

GI number: 119898054

Start: 1932167

End: 1933585

Strand: Reverse

Name: mucD3 [H]

Synonym: azo1763

Alternate gene names: 119898054

Gene position: 1933585-1932167 (Counterclockwise)

Preceding gene: 119898057

Following gene: 119898053

Centisome position: 44.19

GC content: 75.48

Gene sequence:

>1419_bases
ATGTTCTCCCCCGGCACCCGCGTCATCCGCGCAGCAGGCACCGCCCGCAGCCGCCTCGCCGCGCTCGCGCTGTGCGCCGC
CTGTACGCTGGCGGGCTGCCGCCCGGCCGGCGAGGCGCCGGACTTCGGCGCGCTGATGCAGACCCAGGGCCCGGCGGTGG
TCAACATCGTCGCGCTGCGCCCGGCGGCCGCCACCGTGCGGGACAGCCGGCCGCCCGCGCCCGCCGACCCGGCCTACGCG
GTGTCGCCGCAGATCGCCGCCGGCCCCGAGCAGCCCGTGGAAGACCTCGGCTCCGGCTTCATCATCGACGCCGACGGCCT
CATCCTCACCAATGCCCACGTGGTGGCCGGCGCCACCTCGATCACGGTGCGGCTGGCCGACGGCCAGCGCGAATACCCGG
CGCGGCTGGTTGGCGCGGACAGCCACAGCGACGTGGCGCTGCTGCGCATCGACGCCAGCGGCCTGCCGGTGGCCCGCATG
GGCAGCTCGGCCTCGGTCAGCGCCGGCGAATGGGTGGCTGCGATCGGCTCGCCGTTCGGCTTCAGCAACACCATCACCGC
CGGCATCGTCAGCGCCACCGGGCGCAACCTCGGCGAAGGCGGCCAGGTGCCCTTCATCCAGAGCGACGTGGCGGTGAACC
CGGGCAGCTCCGGCGGGCCGCTGATCAACCGCCGCGGCGAGGTCGTCGGCGTCAATTCGATGATCTTCAGCCCCACCGGC
GGCTATCTGGGGCTGTCGTTTGCGATTCCGATCGAGGTCGCGCTCGATGTGGCCCGTCATCTGCAACGCGACGGCGAAAT
CCGGCGCGGGCGCCTCGGCATCTCGGTGCAGCCGCTCAGCGACGGGCTCGCGCGCGCGTTCGGCTTCGACGGCCAGGGCG
TGCTGATCAGCATGGTGGAACCGGGCAGCGCGGCCGAGGCGGCGGGGCTGCGCGCGGGCGACGTGATCCTGGGCTTCGGC
GGCAAGGCGGCCACGCCCGCGGCGCTGCCGCGCATGATCGCGGATTCGGCGCCCGGCAGCCGGCAGGAGGTGGCGCTGTG
GCGCGACCGCCACCCCGAGCGCGTCACGGTGACGATGGGCGAGCACGCCGTGCAGCGCGCGGCCCCGCCCGCCGCGGCGG
CCCCCGCCCACCCGGATCACGGGCTGGTGCTGAGCGCGCTGCCGGCAGAGGTGTGCCGCCAGTACGGCGCCGGCTTCGCG
CTGCGGGTGGACCGCGCGCCGGCCGCGCGCCATGAGGACGAACTGCGCTACGGCGACGTGATCCTCGCCGTCGGCGGACG
GTCCTTCACCAGCCGGGGCGAGTTCGACCGGCTGCTGCAGGAGGCGCCCGGCGACCGCGCCGCGCTGCTGGTACGGCGCG
GTTCGGCCGCCCTCTTCGTCGCGGTGGAGGTGCCCGGGCGGCTGCAGGAGGCGGGTTGA

Upstream 100 bases:

>100_bases
GCGGTGCCCCCGTTTCGCAATCGGCGTACCCGGACGTCCTAGCTTCCTGGCACCGCGTTTGCTTACTCCGCTGTCGTCGG
CCCTCCACGGAGTCATCGCC

Downstream 100 bases:

>100_bases
TCCCGCGCCGCGCCCCCTCGCCGCAGCCACGCCGGCGGCGTGCGCGCGCCGTCGCGCCGCCCACCCCGGGCAGCGCCGCG
GACGCGCGCCGCGCCGACCG

Product: serine protease MucD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MFSPGTRVIRAAGTARSRLAALALCAACTLAGCRPAGEAPDFGALMQTQGPAVVNIVALRPAAATVRDSRPPAPADPAYA
VSPQIAAGPEQPVEDLGSGFIIDADGLILTNAHVVAGATSITVRLADGQREYPARLVGADSHSDVALLRIDASGLPVARM
GSSASVSAGEWVAAIGSPFGFSNTITAGIVSATGRNLGEGGQVPFIQSDVAVNPGSSGGPLINRRGEVVGVNSMIFSPTG
GYLGLSFAIPIEVALDVARHLQRDGEIRRGRLGISVQPLSDGLARAFGFDGQGVLISMVEPGSAAEAAGLRAGDVILGFG
GKAATPAALPRMIADSAPGSRQEVALWRDRHPERVTVTMGEHAVQRAAPPAAAAPAHPDHGLVLSALPAEVCRQYGAGFA
LRVDRAPAARHEDELRYGDVILAVGGRSFTSRGEFDRLLQEAPGDRAALLVRRGSAALFVAVEVPGRLQEAG

Sequences:

>Translated_472_residues
MFSPGTRVIRAAGTARSRLAALALCAACTLAGCRPAGEAPDFGALMQTQGPAVVNIVALRPAAATVRDSRPPAPADPAYA
VSPQIAAGPEQPVEDLGSGFIIDADGLILTNAHVVAGATSITVRLADGQREYPARLVGADSHSDVALLRIDASGLPVARM
GSSASVSAGEWVAAIGSPFGFSNTITAGIVSATGRNLGEGGQVPFIQSDVAVNPGSSGGPLINRRGEVVGVNSMIFSPTG
GYLGLSFAIPIEVALDVARHLQRDGEIRRGRLGISVQPLSDGLARAFGFDGQGVLISMVEPGSAAEAAGLRAGDVILGFG
GKAATPAALPRMIADSAPGSRQEVALWRDRHPERVTVTMGEHAVQRAAPPAAAAPAHPDHGLVLSALPAEVCRQYGAGFA
LRVDRAPAARHEDELRYGDVILAVGGRSFTSRGEFDRLLQEAPGDRAALLVRRGSAALFVAVEVPGRLQEAG
>Mature_472_residues
MFSPGTRVIRAAGTARSRLAALALCAACTLAGCRPAGEAPDFGALMQTQGPAVVNIVALRPAAATVRDSRPPAPADPAYA
VSPQIAAGPEQPVEDLGSGFIIDADGLILTNAHVVAGATSITVRLADGQREYPARLVGADSHSDVALLRIDASGLPVARM
GSSASVSAGEWVAAIGSPFGFSNTITAGIVSATGRNLGEGGQVPFIQSDVAVNPGSSGGPLINRRGEVVGVNSMIFSPTG
GYLGLSFAIPIEVALDVARHLQRDGEIRRGRLGISVQPLSDGLARAFGFDGQGVLISMVEPGSAAEAAGLRAGDVILGFG
GKAATPAALPRMIADSAPGSRQEVALWRDRHPERVTVTMGEHAVQRAAPPAAAAPAHPDHGLVLSALPAEVCRQYGAGFA
LRVDRAPAARHEDELRYGDVILAVGGRSFTSRGEFDRLLQEAPGDRAALLVRRGSAALFVAVEVPGRLQEAG

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=248, Percent_Identity=39.5161290322581, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI24308541, Length=246, Percent_Identity=39.4308943089431, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI7019477, Length=257, Percent_Identity=43.579766536965, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI22129776, Length=247, Percent_Identity=36.0323886639676, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1789629, Length=462, Percent_Identity=34.8484848484849, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1786356, Length=377, Percent_Identity=34.7480106100796, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1789630, Length=352, Percent_Identity=34.9431818181818, Blast_Score=167, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24646839, Length=252, Percent_Identity=40.0793650793651, Blast_Score=159, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 48293; Mature: 48293

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSPGTRVIRAAGTARSRLAALALCAACTLAGCRPAGEAPDFGALMQTQGPAVVNIVALR
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCEEEEEEEC
PAAATVRDSRPPAPADPAYAVSPQIAAGPEQPVEDLGSGFIIDADGLILTNAHVVAGATS
CCHHHHCCCCCCCCCCCCEEECCCCCCCCCCCHHHCCCCEEEECCCEEEECCEEEECCEE
ITVRLADGQREYPARLVGADSHSDVALLRIDASGLPVARMGSSASVSAGEWVAAIGSPFG
EEEEECCCCCCCCEEEECCCCCCCEEEEEECCCCCCHHHCCCCCCCCCCCCHHHHCCCCC
FSNTITAGIVSATGRNLGEGGQVPFIQSDVAVNPGSSGGPLINRRGEVVGVNSMIFSPTG
CCCCHHHHHHHHCCCCCCCCCCCCEEECCCEECCCCCCCCCCCCCCCEEEECEEEECCCC
GYLGLSFAIPIEVALDVARHLQRDGEIRRGRLGISVQPLSDGLARAFGFDGQGVLISMVE
CCEEEEEEEHHHHHHHHHHHHHHCCCEECCEECEEEECHHHHHHHHHCCCCCCEEEEEEC
PGSAAEAAGLRAGDVILGFGGKAATPAALPRMIADSAPGSRQEVALWRDRHPERVTVTMG
CCCCHHHCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCEEHHHHCCCCCEEEEEEC
EHAVQRAAPPAAAAPAHPDHGLVLSALPAEVCRQYGAGFALRVDRAPAARHEDELRYGDV
HHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCE
ILAVGGRSFTSRGEFDRLLQEAPGDRAALLVRRGSAALFVAVEVPGRLQEAG
EEEECCCCCCCCCHHHHHHHHCCCCCEEEEEEECCEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MFSPGTRVIRAAGTARSRLAALALCAACTLAGCRPAGEAPDFGALMQTQGPAVVNIVALR
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCEEEEEEEC
PAAATVRDSRPPAPADPAYAVSPQIAAGPEQPVEDLGSGFIIDADGLILTNAHVVAGATS
CCHHHHCCCCCCCCCCCCEEECCCCCCCCCCCHHHCCCCEEEECCCEEEECCEEEECCEE
ITVRLADGQREYPARLVGADSHSDVALLRIDASGLPVARMGSSASVSAGEWVAAIGSPFG
EEEEECCCCCCCCEEEECCCCCCCEEEEEECCCCCCHHHCCCCCCCCCCCCHHHHCCCCC
FSNTITAGIVSATGRNLGEGGQVPFIQSDVAVNPGSSGGPLINRRGEVVGVNSMIFSPTG
CCCCHHHHHHHHCCCCCCCCCCCCEEECCCEECCCCCCCCCCCCCCCEEEECEEEECCCC
GYLGLSFAIPIEVALDVARHLQRDGEIRRGRLGISVQPLSDGLARAFGFDGQGVLISMVE
CCEEEEEEEHHHHHHHHHHHHHHCCCEECCEECEEEECHHHHHHHHHCCCCCCEEEEEEC
PGSAAEAAGLRAGDVILGFGGKAATPAALPRMIADSAPGSRQEVALWRDRHPERVTVTMG
CCCCHHHCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCEEHHHHCCCCCEEEEEEC
EHAVQRAAPPAAAAPAHPDHGLVLSALPAEVCRQYGAGFALRVDRAPAARHEDELRYGDV
HHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCE
ILAVGGRSFTSRGEFDRLLQEAPGDRAALLVRRGSAALFVAVEVPGRLQEAG
EEEECCCCCCCCCHHHHHHHHCCCCCEEEEEEECCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550509; 11481430 [H]