Click here to switch to the map view.

The map label for this gene is ndh1 [H]

Identifier: 119898057

GI number: 119898057

Start: 1934490

End: 1935986

Strand: Reverse

Name: ndh1 [H]

Synonym: azo1766

Alternate gene names: 119898057

Gene position: 1935986-1934490 (Counterclockwise)

Preceding gene: 119898058

Following gene: 119898054

Centisome position: 44.24

GC content: 73.95

Gene sequence:

>1497_bases
ATGCCTGCCCTCCCCCTGCGCTTTCCCCTGCTTGCGGCGGCCCTGCCCCACGGCGCGCGGCCGCTGTCGCCGGCGCCGCA
TGCGGACCCCGCGTCCACGCCCGGCAGCAGCCGCTTTTCCGGCGAAGCCGACTTTCTGGATGCCACCGGTCAGCCCCGCC
GCAGCCGCAGCGCGGCCGATCTCGCCTCGCGCGAGACGGCCATCGCCCGCCACCGCATCGTCATCGTCGGCGGCGGCGCC
GGCGGGCTGGAGCTGGCGGCGCGCCTGGGCGACAGCGTGGGACGCGACGGCGCGGCGGAGATCATCCTGGTCGATGCGGC
GCTGACCCACGTGTGGAAGCCGCTGCTGCACGAGGTGGCGGCGGGCACGCTCGGGTCGCAGGAAAACGAACTGGACTTCC
TGCAGCAGGCGCGCGACCACCACTTCCGCTTCCACCTCGGCCGGCTGGAATCGCTGGAGCGCGCGCACCGTTCGATCTGG
CTCGCGCCGCTGGTGGACGACGACGGCATGGAAGTGGCGCCGCGCCGGCCGCTGGCCTACGACACGCTGGTGATCGCGGT
GGGCGCGGTCGATAACGACTTCGGCACGCCGGGCGCGTGCGAACATGCGATCTCGCTCAACAACGCCGACGAGGCGCGGC
GCTTCCACCGCCGCCTGCTGGCACTGTGCGCGCGCGCCGAGATGACCACCGGCGAGCCGGTGCACATCGCCATCGTCGGC
GGCGGCGCCACCGGGGTGGAACTGGCGGCCGAACTCACCGGCGCCGCCGGCGAGATTGCCTCTTACGGGCGCGAGCTGCG
CCGCCTCGGGCTGCCGTTGCGGATCTCGCTGATCGAAGCCGGCGACCGCCTGCTGGCCTCGGTACCGCAGGGCCTCGGGC
GCAAGGCGGGCGAAGACCTCGCCGCGCGCGGAGTCGACATCCGCGTGCAGGCCAAGGTGGCCGAGGTGTGCGCGGACTCC
GTGCTGCTGAAAGGCGGCGAGCGCATCGCCGCCGACCTGGTGGTGTGGGCCGCCGGCGTGCAAGGCCCCGAAGTGCTGGA
AAAGCTCGACGGCCTGGTCACCAACGACCGCCGCCAGTTGCTGGTGCGCCCCACGCTGCAGACCACGGTGGATGACGACA
TCTTCGCCTTCGGCGACTGCGCGAGCTGCACGCCCGGCCCGGACGACAAGCCGGTGCCGCCCAAGGCGCAGGCTGCCCAG
CAGCAGGCGCTGCTGCTCACCCGCTCGCTGCAGCGCCGGCTGGCCGGCAAGCCGCCGCTGCGCTTCAGCTACCGCGACCA
CGGCACCATCGTCTCGATGGGGCCGGAGCAGGCGCTGGGCGAGGTCCGCACCGCGCACGGGCGGCGCTACGTCCTGCGCG
GCATCCGCGCGCGCTTCGGCTACTGGCTGCTGTACCGCCGCCACCTCGCGGTGCTGGTGGGCGCCGCGCGCACGGTGCTC
GTCACCGTGGGCCACTGGCTCACGCGGCGGGCGCACCCGCGCGTCAAGCTGCACTGA

Upstream 100 bases:

>100_bases
GTGGTCCAGCACAGCCGGCTCGATTCACGCCACGCCGAGTTGTCGCTGGTGACCACGCTTGCCTATGCGGACCGCTGACG
CGGACGCCACGGAGAACATA

Downstream 100 bases:

>100_bases
AGGCGCCGGCGCCGTCCGGCGCCGTGCGCGTCAGAACACCAGCATGCCGAGGCCCACGCCGAAGATCAGCACGATCAGGA
AGATCGCCAGTGCAATGAAG

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MPALPLRFPLLAAALPHGARPLSPAPHADPASTPGSSRFSGEADFLDATGQPRRSRSAADLASRETAIARHRIVIVGGGA
GGLELAARLGDSVGRDGAAEIILVDAALTHVWKPLLHEVAAGTLGSQENELDFLQQARDHHFRFHLGRLESLERAHRSIW
LAPLVDDDGMEVAPRRPLAYDTLVIAVGAVDNDFGTPGACEHAISLNNADEARRFHRRLLALCARAEMTTGEPVHIAIVG
GGATGVELAAELTGAAGEIASYGRELRRLGLPLRISLIEAGDRLLASVPQGLGRKAGEDLAARGVDIRVQAKVAEVCADS
VLLKGGERIAADLVVWAAGVQGPEVLEKLDGLVTNDRRQLLVRPTLQTTVDDDIFAFGDCASCTPGPDDKPVPPKAQAAQ
QQALLLTRSLQRRLAGKPPLRFSYRDHGTIVSMGPEQALGEVRTAHGRRYVLRGIRARFGYWLLYRRHLAVLVGAARTVL
VTVGHWLTRRAHPRVKLH

Sequences:

>Translated_498_residues
MPALPLRFPLLAAALPHGARPLSPAPHADPASTPGSSRFSGEADFLDATGQPRRSRSAADLASRETAIARHRIVIVGGGA
GGLELAARLGDSVGRDGAAEIILVDAALTHVWKPLLHEVAAGTLGSQENELDFLQQARDHHFRFHLGRLESLERAHRSIW
LAPLVDDDGMEVAPRRPLAYDTLVIAVGAVDNDFGTPGACEHAISLNNADEARRFHRRLLALCARAEMTTGEPVHIAIVG
GGATGVELAAELTGAAGEIASYGRELRRLGLPLRISLIEAGDRLLASVPQGLGRKAGEDLAARGVDIRVQAKVAEVCADS
VLLKGGERIAADLVVWAAGVQGPEVLEKLDGLVTNDRRQLLVRPTLQTTVDDDIFAFGDCASCTPGPDDKPVPPKAQAAQ
QQALLLTRSLQRRLAGKPPLRFSYRDHGTIVSMGPEQALGEVRTAHGRRYVLRGIRARFGYWLLYRRHLAVLVGAARTVL
VTVGHWLTRRAHPRVKLH
>Mature_497_residues
PALPLRFPLLAAALPHGARPLSPAPHADPASTPGSSRFSGEADFLDATGQPRRSRSAADLASRETAIARHRIVIVGGGAG
GLELAARLGDSVGRDGAAEIILVDAALTHVWKPLLHEVAAGTLGSQENELDFLQQARDHHFRFHLGRLESLERAHRSIWL
APLVDDDGMEVAPRRPLAYDTLVIAVGAVDNDFGTPGACEHAISLNNADEARRFHRRLLALCARAEMTTGEPVHIAIVGG
GATGVELAAELTGAAGEIASYGRELRRLGLPLRISLIEAGDRLLASVPQGLGRKAGEDLAARGVDIRVQAKVAEVCADSV
LLKGGERIAADLVVWAAGVQGPEVLEKLDGLVTNDRRQLLVRPTLQTTVDDDIFAFGDCASCTPGPDDKPVPPKAQAAQQ
QALLLTRSLQRRLAGKPPLRFSYRDHGTIVSMGPEQALGEVRTAHGRRYVLRGIRARFGYWLLYRRHLAVLVGAARTVLV
TVGHWLTRRAHPRVKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=433, Percent_Identity=44.3418013856813, Blast_Score=329, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6323794, Length=362, Percent_Identity=26.5193370165746, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323515, Length=357, Percent_Identity=24.0896358543417, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320118, Length=443, Percent_Identity=25.9593679458239, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 53440; Mature: 53309

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALPLRFPLLAAALPHGARPLSPAPHADPASTPGSSRFSGEADFLDATGQPRRSRSAAD
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCHHHH
LASRETAIARHRIVIVGGGAGGLELAARLGDSVGRDGAAEIILVDAALTHVWKPLLHEVA
HHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHH
AGTLGSQENELDFLQQARDHHFRFHLGRLESLERAHRSIWLAPLVDDDGMEVAPRRPLAY
HCCCCCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCC
DTLVIAVGAVDNDFGTPGACEHAISLNNADEARRFHRRLLALCARAEMTTGEPVHIAIVG
EEEEEEEECCCCCCCCCCHHHHHEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
GGATGVELAAELTGAAGEIASYGRELRRLGLPLRISLIEAGDRLLASVPQGLGRKAGEDL
CCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEHHCHHHHHHHHHHHCHHCCCHH
AARGVDIRVQAKVAEVCADSVLLKGGERIAADLVVWAAGVQGPEVLEKLDGLVTNDRRQL
HHCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEE
LVRPTLQTTVDDDIFAFGDCASCTPGPDDKPVPPKAQAAQQQALLLTRSLQRRLAGKPPL
EECCCHHHCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCE
RFSYRDHGTIVSMGPEQALGEVRTAHGRRYVLRGIRARFGYWLLYRRHLAVLVGAARTVL
EEEECCCCEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTVGHWLTRRAHPRVKLH
HHHHHHHHHCCCCCEECC
>Mature Secondary Structure 
PALPLRFPLLAAALPHGARPLSPAPHADPASTPGSSRFSGEADFLDATGQPRRSRSAAD
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCHHHH
LASRETAIARHRIVIVGGGAGGLELAARLGDSVGRDGAAEIILVDAALTHVWKPLLHEVA
HHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHH
AGTLGSQENELDFLQQARDHHFRFHLGRLESLERAHRSIWLAPLVDDDGMEVAPRRPLAY
HCCCCCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCC
DTLVIAVGAVDNDFGTPGACEHAISLNNADEARRFHRRLLALCARAEMTTGEPVHIAIVG
EEEEEEEECCCCCCCCCCHHHHHEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
GGATGVELAAELTGAAGEIASYGRELRRLGLPLRISLIEAGDRLLASVPQGLGRKAGEDL
CCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEHHCHHHHHHHHHHHCHHCCCHH
AARGVDIRVQAKVAEVCADSVLLKGGERIAADLVVWAAGVQGPEVLEKLDGLVTNDRRQL
HHCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEE
LVRPTLQTTVDDDIFAFGDCASCTPGPDDKPVPPKAQAAQQQALLLTRSLQRRLAGKPPL
EECCCHHHCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCE
RFSYRDHGTIVSMGPEQALGEVRTAHGRRYVLRGIRARFGYWLLYRRHLAVLVGAARTVL
EEEECCCCEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTVGHWLTRRAHPRVKLH
HHHHHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]