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The map label for this gene is appC [C]

Identifier: 119897864

GI number: 119897864

Start: 1731121

End: 1732533

Strand: Direct

Name: appC [C]

Synonym: azo1573

Alternate gene names: 119897864

Gene position: 1731121-1732533 (Clockwise)

Preceding gene: 119897863

Following gene: 119897865

Centisome position: 39.56

GC content: 68.44

Gene sequence:

>1413_bases
ATGATGGCGGGCTTTCAACCCGTGCTGTTGTGGACCGACGCGCTGCTGTTCCTGCTGCTGCTCGCCGGCGTTGGGGTGGT
CCTGCATGCGCGCGCGCAACCGCCACTGCGGCAGGCCTGGCGCAAGGTGGGCGAGCGCGCGACCGGCATGGTGTCGGCGT
GCGTGCTGGGGGTGTTCATCGTGATCGGCGTGATGGACAGCCTGCATTACCGGCCGCAACTGGCGCAGCTGGAAGGGGCT
GCGGGGCCCTCCGAAACCTACTCGGCCGAGGTCCTGAGCCTGCTCGACCGGGTGCTGGAGCCACTGCGGCTGAATACCGA
GAAGACCTATTCGGCGCCGCTCGCCGCCACCCTGTACCAGCGCGAAACCGTGGAAACCGGGAGCGGGCAGGTTCGGACGT
ATCCGCGCCTGCAGCACGGTGGCGCCCACCTGCAGGCGCCGGAAGCGGAGTTCGCCCCGGATCTGGCCCGCCGCCTGGGG
CACGCAGCGGGGTTGGCGGTGGTCGCCAGCGTCGCGCTGCTGGCGGCGCTGGCGGTGGGCCTTGCCGCCCGTCATGGCGG
GCCGATCCGGGCCGCCGCCGCGGTGCTTGCGGGCCGTACCGTGCTGGCGTGGCGTGCGGCGTGGGTTGCATGCAGCATCA
TCGCGCTGGTCGTGGCGGTGGTGGTGATGCTGGCGCCGTATTACCACGTGCTCGGTACCGACAAAGTCGGCCAGGACGTG
CTCTATCTCTCCCTGAAGAGCGTGCGGACCGCCCTCGTGATCGGGACCGTCACCACGCTGGTGATGCTGCCGTTCGCCAT
CGCGCTCGGCATCGCCGCGGGCTACCTGGGCGGGTGGGTGGATGACGCCGTGCAGTACGTCTATACGGTGCTCAACGCGA
TTCCCTCGGTGCTGTTGATCGCCGCCGCCGTGCTGATGATGCAGGTGGTGATCGATACCCACCCGCACTGGTTCGGCACT
GCGGCGGAGCGTTCCGATGCGCGCCTGCTTGCGCTGTGCTTCATTCTCGGCATTACCAGCTGGACCGGCCTGTGCCGGCT
GCTGCGGGGCGAAACGCTCAAGCTGCGCGAACTCGAATACGTCCAGGCCGCGCGGGCCTTCGGAGTTGGCACCACAGGCA
TCCTGCGCCGCCACATCCTGCCCAACGTCATGCACATCGTGCTGATCGCCCTGGTCATGGACTTTTCGGGGCTGGTGCTT
GCCGAGGCGGTGCTGTCCTATGTCGGGATCGGGGTCGATCCCACCACCATCAGCTTCGGCACCATGATCAACCTGGCGCG
GGCGGAACTGGCGCGCGAGCCCATGGTGTGGTGGTCGCTTGCTGCGGCCTTCGTGTTCATGTTCGTGCTGGTCCTGGCGG
CCAACCTGTTTGCCGACGTCGTGCGCGACGCCTTCGATCCGCGCCGGCGCTGA

Upstream 100 bases:

>100_bases
TGGTGCGCGCCATGGTGTTCATCGGCTCGCTGCTCTACATCGTCGGCCTGATCCTGACCGACCTGTCGTACACGCTGGTC
GATCCGCGGGTGAGGCTGGG

Downstream 100 bases:

>100_bases
CTGCGTTGGCGCGCTCCTTGCTCGGGTATCTGGCCACGCGGCCGAACCATCGCTGTGCGCGTCACTCTGATGATCTAAAC
CCGACAAAGCTGCGATCCCC

Product: oligopeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MMAGFQPVLLWTDALLFLLLLAGVGVVLHARAQPPLRQAWRKVGERATGMVSACVLGVFIVIGVMDSLHYRPQLAQLEGA
AGPSETYSAEVLSLLDRVLEPLRLNTEKTYSAPLAATLYQRETVETGSGQVRTYPRLQHGGAHLQAPEAEFAPDLARRLG
HAAGLAVVASVALLAALAVGLAARHGGPIRAAAAVLAGRTVLAWRAAWVACSIIALVVAVVVMLAPYYHVLGTDKVGQDV
LYLSLKSVRTALVIGTVTTLVMLPFAIALGIAAGYLGGWVDDAVQYVYTVLNAIPSVLLIAAAVLMMQVVIDTHPHWFGT
AAERSDARLLALCFILGITSWTGLCRLLRGETLKLRELEYVQAARAFGVGTTGILRRHILPNVMHIVLIALVMDFSGLVL
AEAVLSYVGIGVDPTTISFGTMINLARAELAREPMVWWSLAAAFVFMFVLVLAANLFADVVRDAFDPRRR

Sequences:

>Translated_470_residues
MMAGFQPVLLWTDALLFLLLLAGVGVVLHARAQPPLRQAWRKVGERATGMVSACVLGVFIVIGVMDSLHYRPQLAQLEGA
AGPSETYSAEVLSLLDRVLEPLRLNTEKTYSAPLAATLYQRETVETGSGQVRTYPRLQHGGAHLQAPEAEFAPDLARRLG
HAAGLAVVASVALLAALAVGLAARHGGPIRAAAAVLAGRTVLAWRAAWVACSIIALVVAVVVMLAPYYHVLGTDKVGQDV
LYLSLKSVRTALVIGTVTTLVMLPFAIALGIAAGYLGGWVDDAVQYVYTVLNAIPSVLLIAAAVLMMQVVIDTHPHWFGT
AAERSDARLLALCFILGITSWTGLCRLLRGETLKLRELEYVQAARAFGVGTTGILRRHILPNVMHIVLIALVMDFSGLVL
AEAVLSYVGIGVDPTTISFGTMINLARAELAREPMVWWSLAAAFVFMFVLVLAANLFADVVRDAFDPRRR
>Mature_470_residues
MMAGFQPVLLWTDALLFLLLLAGVGVVLHARAQPPLRQAWRKVGERATGMVSACVLGVFIVIGVMDSLHYRPQLAQLEGA
AGPSETYSAEVLSLLDRVLEPLRLNTEKTYSAPLAATLYQRETVETGSGQVRTYPRLQHGGAHLQAPEAEFAPDLARRLG
HAAGLAVVASVALLAALAVGLAARHGGPIRAAAAVLAGRTVLAWRAAWVACSIIALVVAVVVMLAPYYHVLGTDKVGQDV
LYLSLKSVRTALVIGTVTTLVMLPFAIALGIAAGYLGGWVDDAVQYVYTVLNAIPSVLLIAAAVLMMQVVIDTHPHWFGT
AAERSDARLLALCFILGITSWTGLCRLLRGETLKLRELEYVQAARAFGVGTTGILRRHILPNVMHIVLIALVMDFSGLVL
AEAVLSYVGIGVDPTTISFGTMINLARAELAREPMVWWSLAAAFVFMFVLVLAANLFADVVRDAFDPRRR

Specific function: Probably Part Of The Binding-Protein-Dependent Transport System Yliabcd; Probably Responsible For The Translocation Of The Substrate Across The Membrane. [C]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=242, Percent_Identity=30.1652892561983, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787498, Length=296, Percent_Identity=28.7162162162162, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787760, Length=240, Percent_Identity=27.0833333333333, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788505, Length=241, Percent_Identity=28.6307053941909, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789889, Length=242, Percent_Identity=28.9256198347107, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789964, Length=244, Percent_Identity=32.3770491803279, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 50409; Mature: 50409

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAGFQPVLLWTDALLFLLLLAGVGVVLHARAQPPLRQAWRKVGERATGMVSACVLGVFI
CCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGVMDSLHYRPQLAQLEGAAGPSETYSAEVLSLLDRVLEPLRLNTEKTYSAPLAATLYQ
HHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHH
RETVETGSGQVRTYPRLQHGGAHLQAPEAEFAPDLARRLGHAAGLAVVASVALLAALAVG
HHHHCCCCCCEEECCCHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAARHGGPIRAAAAVLAGRTVLAWRAAWVACSIIALVVAVVVMLAPYYHVLGTDKVGQDV
HHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LYLSLKSVRTALVIGTVTTLVMLPFAIALGIAAGYLGGWVDDAVQYVYTVLNAIPSVLLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAAVLMMQVVIDTHPHWFGTAAERSDARLLALCFILGITSWTGLCRLLRGETLKLRELEY
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
VQAARAFGVGTTGILRRHILPNVMHIVLIALVMDFSGLVLAEAVLSYVGIGVDPTTISFG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHH
TMINLARAELAREPMVWWSLAAAFVFMFVLVLAANLFADVVRDAFDPRRR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MMAGFQPVLLWTDALLFLLLLAGVGVVLHARAQPPLRQAWRKVGERATGMVSACVLGVFI
CCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGVMDSLHYRPQLAQLEGAAGPSETYSAEVLSLLDRVLEPLRLNTEKTYSAPLAATLYQ
HHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHH
RETVETGSGQVRTYPRLQHGGAHLQAPEAEFAPDLARRLGHAAGLAVVASVALLAALAVG
HHHHCCCCCCEEECCCHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAARHGGPIRAAAAVLAGRTVLAWRAAWVACSIIALVVAVVVMLAPYYHVLGTDKVGQDV
HHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LYLSLKSVRTALVIGTVTTLVMLPFAIALGIAAGYLGGWVDDAVQYVYTVLNAIPSVLLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAAVLMMQVVIDTHPHWFGTAAERSDARLLALCFILGITSWTGLCRLLRGETLKLRELEY
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
VQAARAFGVGTTGILRRHILPNVMHIVLIALVMDFSGLVLAEAVLSYVGIGVDPTTISFG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHH
TMINLARAELAREPMVWWSLAAAFVFMFVLVLAANLFADVVRDAFDPRRR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]