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The map label for this gene is appB [C]

Identifier: 119897863

GI number: 119897863

Start: 1730147

End: 1731124

Strand: Direct

Name: appB [C]

Synonym: azo1572

Alternate gene names: 119897863

Gene position: 1730147-1731124 (Clockwise)

Preceding gene: 119897862

Following gene: 119897864

Centisome position: 39.54

GC content: 64.93

Gene sequence:

>978_bases
ATGCTGGCCTACATCGTCCGCCGCCTGCTCTACGCCATTCCCATCCTGGTCGGCGTCAATCTGCTGACCTTCGTGCTGTT
CTTCGTCGTGAATTCGCCCGACGACATGGCGCGCATGCAGATCGGCGTCAAACGCGCCACGCCCGAGGCGATCGAGCGCT
GGAAGGTCGAGCGCGGCTATGACCGCCCGCTGCTGGTGAATACCGAGGCCAAGGGCCTGGAACGGGTGACCGACACGATC
TTCTTTGACAAGTCCCTGCGCATGTTCGCGTTCGATTTCGGCCAGGCCGACGACGGCCGCGACATCGGCCGCGAGATCCG
CACCCGCATGGGGCCGTCGCTCGCAATCGCGCTGCCGACCTTCGCGCTCGGCCTGTTCGCCGCGGTCAGCATGGCGCTGC
TGCTGGTGTTCTTCCGCGCCACCTACCTGGATTTCTGGGGCGTGGTGCTGTGTGTCGGCATGATGTCGATCTCCAGCCTG
TTCTACATCATCGGTGGCCAGTGGCTGGTTTCCAAACTGTGGGCGCTGGTGCCGATTTCCGGCTACGCCGGCGGTCTGGA
CGCCGCCCGCTTCCTGGTGCTGCCGGTGCTGATCAGCGTGATCGGCGGGGTGGGGTCGAGCGTGCGCTGGTATCGGACGC
TGTTCCTTGAAGAGATCTCGCGCGACTACGTCCGCACCGCGCGCGCGAAGGGGCTGTCCGAACTGGCCGTGCTGTTCCGC
CACGTGCTCAAGAACGCGATGATCCCCATCCTGACCGGCGTGGTCGTGCTGATCCCGCTGCTGTTCCTCGGCAGCCTGCT
GGTGGAATCCTTTTTCGCCATTCCGGGGCTGGGCAGCTACACGATCGACGCGATCAACGCGCAGGACTTCGCCGTGGTGC
GCGCCATGGTGTTCATCGGCTCGCTGCTCTACATCGTCGGCCTGATCCTGACCGACCTGTCGTACACGCTGGTCGATCCG
CGGGTGAGGCTGGGATGA

Upstream 100 bases:

>100_bases
CTCGTATTGGCCGCTGCGGTAGCGCCCGCGCTGCTGCACTGGCGACGGCACGAGCGCGGCACCGCGCGTACCGCAACGGC
CGGATCGGAGGCGCGCTGAG

Downstream 100 bases:

>100_bases
TGGCGGGCTTTCAACCCGTGCTGTTGTGGACCGACGCGCTGCTGTTCCTGCTGCTGCTCGCCGGCGTTGGGGTGGTCCTG
CATGCGCGCGCGCAACCGCC

Product: putative oligopeptide ABC transporter permease

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MLAYIVRRLLYAIPILVGVNLLTFVLFFVVNSPDDMARMQIGVKRATPEAIERWKVERGYDRPLLVNTEAKGLERVTDTI
FFDKSLRMFAFDFGQADDGRDIGREIRTRMGPSLAIALPTFALGLFAAVSMALLLVFFRATYLDFWGVVLCVGMMSISSL
FYIIGGQWLVSKLWALVPISGYAGGLDAARFLVLPVLISVIGGVGSSVRWYRTLFLEEISRDYVRTARAKGLSELAVLFR
HVLKNAMIPILTGVVVLIPLLFLGSLLVESFFAIPGLGSYTIDAINAQDFAVVRAMVFIGSLLYIVGLILTDLSYTLVDP
RVRLG

Sequences:

>Translated_325_residues
MLAYIVRRLLYAIPILVGVNLLTFVLFFVVNSPDDMARMQIGVKRATPEAIERWKVERGYDRPLLVNTEAKGLERVTDTI
FFDKSLRMFAFDFGQADDGRDIGREIRTRMGPSLAIALPTFALGLFAAVSMALLLVFFRATYLDFWGVVLCVGMMSISSL
FYIIGGQWLVSKLWALVPISGYAGGLDAARFLVLPVLISVIGGVGSSVRWYRTLFLEEISRDYVRTARAKGLSELAVLFR
HVLKNAMIPILTGVVVLIPLLFLGSLLVESFFAIPGLGSYTIDAINAQDFAVVRAMVFIGSLLYIVGLILTDLSYTLVDP
RVRLG
>Mature_325_residues
MLAYIVRRLLYAIPILVGVNLLTFVLFFVVNSPDDMARMQIGVKRATPEAIERWKVERGYDRPLLVNTEAKGLERVTDTI
FFDKSLRMFAFDFGQADDGRDIGREIRTRMGPSLAIALPTFALGLFAAVSMALLLVFFRATYLDFWGVVLCVGMMSISSL
FYIIGGQWLVSKLWALVPISGYAGGLDAARFLVLPVLISVIGGVGSSVRWYRTLFLEEISRDYVRTARAKGLSELAVLFR
HVLKNAMIPILTGVVVLIPLLFLGSLLVESFFAIPGLGSYTIDAINAQDFAVVRAMVFIGSLLYIVGLILTDLSYTLVDP
RVRLG

Specific function: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=351, Percent_Identity=27.3504273504274, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787053, Length=333, Percent_Identity=28.2282282282282, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788504, Length=361, Percent_Identity=26.5927977839335, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1789888, Length=336, Percent_Identity=25.297619047619, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1787497, Length=330, Percent_Identity=24.8484848484848, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787761, Length=348, Percent_Identity=27.2988505747126, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787550, Length=264, Percent_Identity=23.8636363636364, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36005; Mature: 36005

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAYIVRRLLYAIPILVGVNLLTFVLFFVVNSPDDMARMQIGVKRATPEAIERWKVERGY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCC
DRPLLVNTEAKGLERVTDTIFFDKSLRMFAFDFGQADDGRDIGREIRTRMGPSLAIALPT
CCCEEECCCHHHHHHHHHHHHHHCCHHHHHEECCCCCCCHHHHHHHHHHCCCCHHHHHHH
FALGLFAAVSMALLLVFFRATYLDFWGVVLCVGMMSISSLFYIIGGQWLVSKLWALVPIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GYAGGLDAARFLVLPVLISVIGGVGSSVRWYRTLFLEEISRDYVRTARAKGLSELAVLFR
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HVLKNAMIPILTGVVVLIPLLFLGSLLVESFFAIPGLGSYTIDAINAQDFAVVRAMVFIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHH
SLLYIVGLILTDLSYTLVDPRVRLG
HHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLAYIVRRLLYAIPILVGVNLLTFVLFFVVNSPDDMARMQIGVKRATPEAIERWKVERGY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCC
DRPLLVNTEAKGLERVTDTIFFDKSLRMFAFDFGQADDGRDIGREIRTRMGPSLAIALPT
CCCEEECCCHHHHHHHHHHHHHHCCHHHHHEECCCCCCCHHHHHHHHHHCCCCHHHHHHH
FALGLFAAVSMALLLVFFRATYLDFWGVVLCVGMMSISSLFYIIGGQWLVSKLWALVPIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GYAGGLDAARFLVLPVLISVIGGVGSSVRWYRTLFLEEISRDYVRTARAKGLSELAVLFR
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HVLKNAMIPILTGVVVLIPLLFLGSLLVESFFAIPGLGSYTIDAINAQDFAVVRAMVFIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHH
SLLYIVGLILTDLSYTLVDPRVRLG
HHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]