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The map label for this gene is pgi [H]

Identifier: 119897810

GI number: 119897810

Start: 1663676

End: 1665385

Strand: Reverse

Name: pgi [H]

Synonym: azo1519

Alternate gene names: 119897810

Gene position: 1665385-1663676 (Counterclockwise)

Preceding gene: 119897811

Following gene: 119897808

Centisome position: 38.06

GC content: 67.72

Gene sequence:

>1710_bases
ATGGCATACAATCTGGGAGTACCGCCGGGGTGGCGGAAAGCAACTCGAAATCTTCCGGCTCTATCGCCGCCAGTCATCGT
GACCGACACCTTTACTCCTCCTCAGCGTCTTCCGGTCTGGTCCTCTCTCGAGCAACACGCAGCGCGCCTGCGCGCGACCC
GCGTGCGCACGCTGTTCGACACCGACGCCGGGCGCTTCCAGCGCCTTTCGCGCAGCGTTTGCGGTCTTACGGTCGATTTC
TCCAAGCAGCGCCTCGACGCCGCAGCGCTTGCCGACCTGCTCGAACTCGCCTCGGCCGCCGGCCTTCAGGACGGCATCGC
CGGGCTGTTCGGGGCCGCGCAGATGAACTTCACCGAAGGTCGCGCCGCGCTGCACATGGCGCTCCGCGGCAGTTGCCCCG
CACCAGGCGGCGAAGATGTCACGCGCTATTTCCGCGAGGCGCGCAGTTTCGCGCGCGCGCTGCGCGAAGGCGGCATCAAG
GGCGCAACCGGCAAGTCGATCAACCATGTCATCAACCTCGGCATCGGCGGCTCGGACCTCGGCCCGCGCATGGTGTTCGA
GGCCCTGGCGCACACCCACCGGCCGGTCAAGGTGGATTTCGTGGCCAACATCGACCCGCGCGACCTGGACGAAGCGCTCG
CCGGCGTGGATCCGGAGCGCACACTTTTCATCGTCTCGTCGAAGAGCTTCGGCACTGCCGAAACGCTCTCCAACGCCACT
GCCGCCCGTGCCTGGCTGGCCTCCACGCTGCCAGCCCGGGTGGCGGACAACGCCCTCGCCGTCCATTTCGCGGCCGTCAG
CAATGCAACCGCCAGCGCCGCGGCCTTCGGCATTCCGCCGGAGCGGGTGTTTCCGCTGCCGGAATGGGTAGGCGGCCGGT
ACTCGGTGTGGTCGGCCATCGGTCTGCCGCTGCTGATCGCCTTTGGCGAAGCCGGCTTCGACGCTTTCCTCGCCGGCGGT
CGCGACCTGGACCAGCACTTCCTTAAAGCCCCGCTCGCCGACAACCTACCGGTGCTGATGGGGCTGGTCGGGCTATGGAA
TACCGACTTCCTCGGCCTCGAGACCCTGGCGGTGCTGCCCTACGCCCACGGCCTGCGCAACTTCGCGATGTGGCTGCAGC
AGCTCGAAATGGAAAGCAACGGCAAGCGGACGCTGCGCAACGGAGAAGCCAGCGCGGTGCAGACCTCGCCGGTGGTATGG
GGTGGCGTAGGCACGGTGGGCCAGCACGCGTTCCACCAGCTTTTCTACCAGGGCACGCGCACCATCCCGATGGACTTCAT
CGTGCCGGTGGGTGACGACGATCCGCGCCAGCGCGGGCTGGTGGACAACGCGTTCGCACAGGCCGCCGCGCTGATGAACG
GGCGCGACCTCGCCACCGCCACGGCGGCACTTGCGGCCAAGGGGATGACGCCCGACGAGGTGGAGCGCCTCGCCCCTCAT
CTCGTGTGTCCCGGCAACCAGCCCAGCACGACGATCCTGCTGCCGCAACTCGACGCATATCACCTCGGCGCGCTGCTTGC
GTTGTACGAACACAAGGTGTTCGTCCAGGGCTGGATCTGGGGCATCAACAGCTTCGACCAGTACGGCGTGGAACTCGGCA
AGGAAATGGCGCGGGCGCTGGCGCAAGGTGGCAGCGCCGAGTGCGATGCTTCGACCGCCGGCCTGATGGCCGCCGCAGCG
GCCATCAGGGCCTCGAACCGCGCCCGCTGA

Upstream 100 bases:

>100_bases
CCGGCATACGGACGATGCCGATCCGCGGCAACAGCACGAGTTGCAGGTTGTTACTCATCTACGAGGAGCGCCGCCCCGGC
GCGCAGGCGCCTGCGCCTGA

Downstream 100 bases:

>100_bases
GGGTGGTTCGACAGCGGGAGAGGTCAGGCAAGCCGCAGGAAATTGTCGCGGTAGTGGCGGAGTTCGCCGATCGACTCGTG
GATGTCGGCGAGCGCCTCGT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MAYNLGVPPGWRKATRNLPALSPPVIVTDTFTPPQRLPVWSSLEQHAARLRATRVRTLFDTDAGRFQRLSRSVCGLTVDF
SKQRLDAAALADLLELASAAGLQDGIAGLFGAAQMNFTEGRAALHMALRGSCPAPGGEDVTRYFREARSFARALREGGIK
GATGKSINHVINLGIGGSDLGPRMVFEALAHTHRPVKVDFVANIDPRDLDEALAGVDPERTLFIVSSKSFGTAETLSNAT
AARAWLASTLPARVADNALAVHFAAVSNATASAAAFGIPPERVFPLPEWVGGRYSVWSAIGLPLLIAFGEAGFDAFLAGG
RDLDQHFLKAPLADNLPVLMGLVGLWNTDFLGLETLAVLPYAHGLRNFAMWLQQLEMESNGKRTLRNGEASAVQTSPVVW
GGVGTVGQHAFHQLFYQGTRTIPMDFIVPVGDDDPRQRGLVDNAFAQAAALMNGRDLATATAALAAKGMTPDEVERLAPH
LVCPGNQPSTTILLPQLDAYHLGALLALYEHKVFVQGWIWGINSFDQYGVELGKEMARALAQGGSAECDASTAGLMAAAA
AIRASNRAR

Sequences:

>Translated_569_residues
MAYNLGVPPGWRKATRNLPALSPPVIVTDTFTPPQRLPVWSSLEQHAARLRATRVRTLFDTDAGRFQRLSRSVCGLTVDF
SKQRLDAAALADLLELASAAGLQDGIAGLFGAAQMNFTEGRAALHMALRGSCPAPGGEDVTRYFREARSFARALREGGIK
GATGKSINHVINLGIGGSDLGPRMVFEALAHTHRPVKVDFVANIDPRDLDEALAGVDPERTLFIVSSKSFGTAETLSNAT
AARAWLASTLPARVADNALAVHFAAVSNATASAAAFGIPPERVFPLPEWVGGRYSVWSAIGLPLLIAFGEAGFDAFLAGG
RDLDQHFLKAPLADNLPVLMGLVGLWNTDFLGLETLAVLPYAHGLRNFAMWLQQLEMESNGKRTLRNGEASAVQTSPVVW
GGVGTVGQHAFHQLFYQGTRTIPMDFIVPVGDDDPRQRGLVDNAFAQAAALMNGRDLATATAALAAKGMTPDEVERLAPH
LVCPGNQPSTTILLPQLDAYHLGALLALYEHKVFVQGWIWGINSFDQYGVELGKEMARALAQGGSAECDASTAGLMAAAA
AIRASNRAR
>Mature_568_residues
AYNLGVPPGWRKATRNLPALSPPVIVTDTFTPPQRLPVWSSLEQHAARLRATRVRTLFDTDAGRFQRLSRSVCGLTVDFS
KQRLDAAALADLLELASAAGLQDGIAGLFGAAQMNFTEGRAALHMALRGSCPAPGGEDVTRYFREARSFARALREGGIKG
ATGKSINHVINLGIGGSDLGPRMVFEALAHTHRPVKVDFVANIDPRDLDEALAGVDPERTLFIVSSKSFGTAETLSNATA
ARAWLASTLPARVADNALAVHFAAVSNATASAAAFGIPPERVFPLPEWVGGRYSVWSAIGLPLLIAFGEAGFDAFLAGGR
DLDQHFLKAPLADNLPVLMGLVGLWNTDFLGLETLAVLPYAHGLRNFAMWLQQLEMESNGKRTLRNGEASAVQTSPVVWG
GVGTVGQHAFHQLFYQGTRTIPMDFIVPVGDDDPRQRGLVDNAFAQAAALMNGRDLATATAALAAKGMTPDEVERLAPHL
VCPGNQPSTTILLPQLDAYHLGALLALYEHKVFVQGWIWGINSFDQYGVELGKEMARALAQGGSAECDASTAGLMAAAAA
IRASNRAR

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=544, Percent_Identity=43.1985294117647, Blast_Score=431, Evalue=1e-121,
Organism=Homo sapiens, GI296080693, Length=544, Percent_Identity=39.8897058823529, Blast_Score=381, Evalue=1e-106,
Organism=Escherichia coli, GI1790457, Length=546, Percent_Identity=40.4761904761905, Blast_Score=412, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI71996708, Length=539, Percent_Identity=41.3729128014842, Blast_Score=415, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI71996703, Length=539, Percent_Identity=41.3729128014842, Blast_Score=415, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6319673, Length=552, Percent_Identity=40.3985507246377, Blast_Score=396, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24651916, Length=535, Percent_Identity=40.3738317757009, Blast_Score=393, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24651914, Length=535, Percent_Identity=40.3738317757009, Blast_Score=393, Evalue=1e-109,
Organism=Drosophila melanogaster, GI17737445, Length=535, Percent_Identity=40.3738317757009, Blast_Score=393, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 60660; Mature: 60529

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYNLGVPPGWRKATRNLPALSPPVIVTDTFTPPQRLPVWSSLEQHAARLRATRVRTLFD
CCCCCCCCCCHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
TDAGRFQRLSRSVCGLTVDFSKQRLDAAALADLLELASAAGLQDGIAGLFGAAQMNFTEG
CCHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC
RAALHMALRGSCPAPGGEDVTRYFREARSFARALREGGIKGATGKSINHVINLGIGGSDL
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCC
GPRMVFEALAHTHRPVKVDFVANIDPRDLDEALAGVDPERTLFIVSSKSFGTAETLSNAT
CHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHH
AARAWLASTLPARVADNALAVHFAAVSNATASAAAFGIPPERVFPLPEWVGGRYSVWSAI
HHHHHHHHHCCHHHCCCHHEEEEEHHCCCCHHHHCCCCCHHHCCCCHHHCCCCHHHHHHH
GLPLLIAFGEAGFDAFLAGGRDLDQHFLKAPLADNLPVLMGLVGLWNTDFLGLETLAVLP
HHHHHHHCCCCCHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
YAHGLRNFAMWLQQLEMESNGKRTLRNGEASAVQTSPVVWGGVGTVGQHAFHQLFYQGTR
HHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEECCCEEECCCCHHHHHHHHHHHHCCCC
TIPMDFIVPVGDDDPRQRGLVDNAFAQAAALMNGRDLATATAALAAKGMTPDEVERLAPH
CCCCEEEEECCCCCHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCE
LVCPGNQPSTTILLPQLDAYHLGALLALYEHKVFVQGWIWGINSFDQYGVELGKEMARAL
EECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHH
AQGGSAECDASTAGLMAAAAAIRASNRAR
HCCCCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AYNLGVPPGWRKATRNLPALSPPVIVTDTFTPPQRLPVWSSLEQHAARLRATRVRTLFD
CCCCCCCCCHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
TDAGRFQRLSRSVCGLTVDFSKQRLDAAALADLLELASAAGLQDGIAGLFGAAQMNFTEG
CCHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC
RAALHMALRGSCPAPGGEDVTRYFREARSFARALREGGIKGATGKSINHVINLGIGGSDL
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCC
GPRMVFEALAHTHRPVKVDFVANIDPRDLDEALAGVDPERTLFIVSSKSFGTAETLSNAT
CHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHH
AARAWLASTLPARVADNALAVHFAAVSNATASAAAFGIPPERVFPLPEWVGGRYSVWSAI
HHHHHHHHHCCHHHCCCHHEEEEEHHCCCCHHHHCCCCCHHHCCCCHHHCCCCHHHHHHH
GLPLLIAFGEAGFDAFLAGGRDLDQHFLKAPLADNLPVLMGLVGLWNTDFLGLETLAVLP
HHHHHHHCCCCCHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
YAHGLRNFAMWLQQLEMESNGKRTLRNGEASAVQTSPVVWGGVGTVGQHAFHQLFYQGTR
HHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEECCCEEECCCCHHHHHHHHHHHHCCCC
TIPMDFIVPVGDDDPRQRGLVDNAFAQAAALMNGRDLATATAALAAKGMTPDEVERLAPH
CCCCEEEEECCCCCHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCE
LVCPGNQPSTTILLPQLDAYHLGALLALYEHKVFVQGWIWGINSFDQYGVELGKEMARAL
EECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHH
AQGGSAECDASTAGLMAAAAAIRASNRAR
HCCCCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA