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The map label for this gene is yhfN [H]

Identifier: 119897808

GI number: 119897808

Start: 1661656

End: 1662909

Strand: Reverse

Name: yhfN [H]

Synonym: azo1517

Alternate gene names: 119897808

Gene position: 1662909-1661656 (Counterclockwise)

Preceding gene: 119897810

Following gene: 119897807

Centisome position: 38.0

GC content: 68.26

Gene sequence:

>1254_bases
ATGACCGCCGACGCCTTCTCCCTGCTTTTCGTCACCTTCCTGCTGCTTGGCGTGCTTGCGCGCGGCGGCCTGATGCTGCG
CCAGATCCGCCATGTACGCGCACGCCGCGACGAGGTGCCCGCCGCCTTCGCGCAGGACATCAGCCTCGACAGCCACCGCC
GCGCCGCCGACTACACCTGCGCGCGGATGCGCTTGGCGCTGGCCGACACCGTCACCGGCGCACTGCTTGCACTGGTATTG
ACGCTGGGTGGCGGCCTGCAGGCCATCCACGACGTCTGGGCGCGGCTTTTCGATGCGGGGGGCATTGCGCACGGCACCGC
GCTGCTCGCCTCGCTCGCGGTCGTCGGCTGGGTGGTCGAACTGCCCTTCGGCCTCTATCGCACCTTCGTCGTCGAGAAGC
GCTTCGGCTTCAACCGCATGACGCCCGCGCTGTTCGTTGCCGACACGATCAAGAGCACCGCCCTCGCCGCGTTGATCGGG
TTGCCCCTGCTGGGCGGCGTACTGTGGTTGATGGGCGCGATGGGCACGCTGTGGTGGCTGTGGGTGTGGGCGGTATGGAT
GGCCTTCAACCTGCTGGTGCTGCTGGTGTGGCCCACCTTCATCGCGCCGCTGTTCAACACCTTCACGCCGCTTGCGGACG
AGGCGCTCAAGGCGCGGGTCGAAGCCCTGCTCGCCCGTTGCGGCTTCCAGTCGAAAGGCCTGTTCGTGATGGACGGCTCG
CGGCGCTCGGCGCACGGCAATGCCTACTTCACGGGCTTTGGGGCCTCCAAGCGCATCGTGTTCTTCGACACGCTGCTCGC
CAAGCTGCAGCCTGAAGAGGTCGAAGCGGTGCTCGCGCACGAACTCGGTCACTTCCGCCACCATCACATCTTCAAGCGGC
TGGCGGTGCTCGCCCCCGCCGCGCTCGCGCTGTTCGCGCTGCTCGGCGGGTTGATGCAGACGGACTGGTTCTACGCCGGC
CTGGGCGTGAACAGCGCTGGCACCGCGATGGCCCTGGCGCTGTTTTCCCTGGTGCTGCCGGCCTTCAGCTTTCCGTTCGT
GCCACTTGCCAGCCACTGGTCGCGCACGCACGAATTCGAGGCCGACCGCTACGCTGCCCGGCAGGCGAGCGCCGGCCACC
TGGTCGCCGCGCTGGTCAAGCTGTACCGCGACAACGCCGCCACGCTGACACCCGATCCGCTGTATTCGAGCGTATTCGAT
TCGCACCCGCCGGCGGCGGTCCGCATCCTGCGGCTGCAGGCGCAGGGTCGCTGA

Upstream 100 bases:

>100_bases
ATCCACGGCGGTTCCCGGGCAAGTGCGCGTCGCCTCGCGGCCGCTCCGCTCCGGTTTCCGCCCTTCGCAGCCCCTTCCAA
CTTCGCCCTCACCCGCCCGG

Downstream 100 bases:

>100_bases
GGTGGGCAAACCCGCGGCACGCACCCGCAGCAACGCCGCTGCCACCACGCCGGGCACCATTACCGCCGCGTTCGGGCGCC
ACTACGAGGTGGAGACGGCC

Product: putative metalloprotease

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MTADAFSLLFVTFLLLGVLARGGLMLRQIRHVRARRDEVPAAFAQDISLDSHRRAADYTCARMRLALADTVTGALLALVL
TLGGGLQAIHDVWARLFDAGGIAHGTALLASLAVVGWVVELPFGLYRTFVVEKRFGFNRMTPALFVADTIKSTALAALIG
LPLLGGVLWLMGAMGTLWWLWVWAVWMAFNLLVLLVWPTFIAPLFNTFTPLADEALKARVEALLARCGFQSKGLFVMDGS
RRSAHGNAYFTGFGASKRIVFFDTLLAKLQPEEVEAVLAHELGHFRHHHIFKRLAVLAPAALALFALLGGLMQTDWFYAG
LGVNSAGTAMALALFSLVLPAFSFPFVPLASHWSRTHEFEADRYAARQASAGHLVAALVKLYRDNAATLTPDPLYSSVFD
SHPPAAVRILRLQAQGR

Sequences:

>Translated_417_residues
MTADAFSLLFVTFLLLGVLARGGLMLRQIRHVRARRDEVPAAFAQDISLDSHRRAADYTCARMRLALADTVTGALLALVL
TLGGGLQAIHDVWARLFDAGGIAHGTALLASLAVVGWVVELPFGLYRTFVVEKRFGFNRMTPALFVADTIKSTALAALIG
LPLLGGVLWLMGAMGTLWWLWVWAVWMAFNLLVLLVWPTFIAPLFNTFTPLADEALKARVEALLARCGFQSKGLFVMDGS
RRSAHGNAYFTGFGASKRIVFFDTLLAKLQPEEVEAVLAHELGHFRHHHIFKRLAVLAPAALALFALLGGLMQTDWFYAG
LGVNSAGTAMALALFSLVLPAFSFPFVPLASHWSRTHEFEADRYAARQASAGHLVAALVKLYRDNAATLTPDPLYSSVFD
SHPPAAVRILRLQAQGR
>Mature_416_residues
TADAFSLLFVTFLLLGVLARGGLMLRQIRHVRARRDEVPAAFAQDISLDSHRRAADYTCARMRLALADTVTGALLALVLT
LGGGLQAIHDVWARLFDAGGIAHGTALLASLAVVGWVVELPFGLYRTFVVEKRFGFNRMTPALFVADTIKSTALAALIGL
PLLGGVLWLMGAMGTLWWLWVWAVWMAFNLLVLLVWPTFIAPLFNTFTPLADEALKARVEALLARCGFQSKGLFVMDGSR
RSAHGNAYFTGFGASKRIVFFDTLLAKLQPEEVEAVLAHELGHFRHHHIFKRLAVLAPAALALFALLGGLMQTDWFYAGL
GVNSAGTAMALALFSLVLPAFSFPFVPLASHWSRTHEFEADRYAARQASAGHLVAALVKLYRDNAATLTPDPLYSSVFDS
HPPAAVRILRLQAQGR

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=433, Percent_Identity=26.3279445727483, Blast_Score=168, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17505484, Length=416, Percent_Identity=29.3269230769231, Blast_Score=181, Evalue=8e-46,
Organism=Saccharomyces cerevisiae, GI6322577, Length=411, Percent_Identity=32.1167883211679, Blast_Score=197, Evalue=2e-51,
Organism=Drosophila melanogaster, GI19922414, Length=415, Percent_Identity=30.3614457831325, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24654305, Length=454, Percent_Identity=26.8722466960352, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI78707252, Length=311, Percent_Identity=28.2958199356913, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI78707254, Length=311, Percent_Identity=28.2958199356913, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 45537; Mature: 45406

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADAFSLLFVTFLLLGVLARGGLMLRQIRHVRARRDEVPAAFAQDISLDSHRRAADYTC
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHH
ARMRLALADTVTGALLALVLTLGGGLQAIHDVWARLFDAGGIAHGTALLASLAVVGWVVE
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LPFGLYRTFVVEKRFGFNRMTPALFVADTIKSTALAALIGLPLLGGVLWLMGAMGTLWWL
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVWAVWMAFNLLVLLVWPTFIAPLFNTFTPLADEALKARVEALLARCGFQSKGLFVMDGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
RRSAHGNAYFTGFGASKRIVFFDTLLAKLQPEEVEAVLAHELGHFRHHHIFKRLAVLAPA
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALALFALLGGLMQTDWFYAGLGVNSAGTAMALALFSLVLPAFSFPFVPLASHWSRTHEFE
HHHHHHHHHHHHHHCHHEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
ADRYAARQASAGHLVAALVKLYRDNAATLTPDPLYSSVFDSHPPAAVRILRLQAQGR
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
TADAFSLLFVTFLLLGVLARGGLMLRQIRHVRARRDEVPAAFAQDISLDSHRRAADYTC
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHH
ARMRLALADTVTGALLALVLTLGGGLQAIHDVWARLFDAGGIAHGTALLASLAVVGWVVE
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LPFGLYRTFVVEKRFGFNRMTPALFVADTIKSTALAALIGLPLLGGVLWLMGAMGTLWWL
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVWAVWMAFNLLVLLVWPTFIAPLFNTFTPLADEALKARVEALLARCGFQSKGLFVMDGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
RRSAHGNAYFTGFGASKRIVFFDTLLAKLQPEEVEAVLAHELGHFRHHHIFKRLAVLAPA
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALALFALLGGLMQTDWFYAGLGVNSAGTAMALALFSLVLPAFSFPFVPLASHWSRTHEFE
HHHHHHHHHHHHHHCHHEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
ADRYAARQASAGHLVAALVKLYRDNAATLTPDPLYSSVFDSHPPAAVRILRLQAQGR
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]