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The map label for this gene is 119897386

Identifier: 119897386

GI number: 119897386

Start: 1178599

End: 1179525

Strand: Direct

Name: 119897386

Synonym: azo1095

Alternate gene names: NA

Gene position: 1178599-1179525 (Clockwise)

Preceding gene: 119897381

Following gene: 119897387

Centisome position: 26.93

GC content: 64.08

Gene sequence:

>927_bases
ATGACGACAACGGCATTCATCACGCATCGCGAGTGCTGGCTGCATGATATGGGTACCTTCCATCCGGAGTGCCCAGACCG
CCTGTCGGCGATCAACGACCGACTGATTGCAGCGGGGCTGGATCTATATCTTTCGTTTTACGACGCGCCGTACGCCACCG
AAGAGCAGGTGACGCGCGTGCATCCCGCTTCGTACCTCGGCGAGTTGATGGCGAATGTGCCCGAGCACGGCATCCGTCAC
CTCGACCCCGACACCGCGATGAGCCCGAACACGATGAAGGCCGCGTTGCGCTCGGCGGGTGCCGGCGTGCTGGCGACTGA
TCTGGTACTGAAGGGCGAGGTCGAGAGCGCGTTTTGCGCCGTGCGGCCGCCCGGGCATCACGCCGAGAAGGCGAAGGCCA
TGGGGTTCTGCTTCCTCAACAATGTCGCCATCGCGGCGCGCCACGCACTGGAGGCCCACGGACTCGAACGCGTGGCCATT
GTCGATTTCGACGTCCATCACGGCAATGGCACCGAGGACATCTTCCGCGACGATCCGCGCGTGATGATGGTCAGCATCTT
CCAGCATCCGTTCTACCCCTATTCCGGCGTGGAGAATCCGCCCGCGCACATGTGCAACGTGCCGGTGCCGGCCGGTACGC
GCGGCGACGCCTTCAGGCAGATCGTCAGCGACATCTGGGTGCCGGCGCTGCGCAACCACAACCCCCAGGCCATCTTCGTG
TCGGCCGGGTTCGACGCCCACTACGAAGACGACATGGGCTCGCTCGGCCTGGTCGAGTCGGACTATGTGTGGGCAACGCA
GCAGATCAAGAGCGTGGCGGAGGACTGCGGCCACAAGCGCGTCATTTCGGTGCTCGAAGGCGGCTATTCGCTCTCGTCGC
TGGCGCGTTCGGTGGTTGCGCACATCAAGGCGCTGGCCGATCTGTAA

Upstream 100 bases:

>100_bases
AACGCAGATCCGCGCCTGCGCTTCGTCGTGGCGGCGTCAAGACCGCCCGGTTGGAAGCGGATTATGCGGGAAAGTTCGTC
CGGGACAAGGAGAGGGGGGC

Downstream 100 bases:

>100_bases
CCCGTCGACGCCCCCGCAACGGGGCGCGCCCGGGTTTGCCGATAGCGCCCATGTCCGACTTTCGGCGATCGGTTAGAATC
GTCGCTTTATCGTAACGGCC

Product: histone deacetylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTTTAFITHRECWLHDMGTFHPECPDRLSAINDRLIAAGLDLYLSFYDAPYATEEQVTRVHPASYLGELMANVPEHGIRH
LDPDTAMSPNTMKAALRSAGAGVLATDLVLKGEVESAFCAVRPPGHHAEKAKAMGFCFLNNVAIAARHALEAHGLERVAI
VDFDVHHGNGTEDIFRDDPRVMMVSIFQHPFYPYSGVENPPAHMCNVPVPAGTRGDAFRQIVSDIWVPALRNHNPQAIFV
SAGFDAHYEDDMGSLGLVESDYVWATQQIKSVAEDCGHKRVISVLEGGYSLSSLARSVVAHIKALADL

Sequences:

>Translated_308_residues
MTTTAFITHRECWLHDMGTFHPECPDRLSAINDRLIAAGLDLYLSFYDAPYATEEQVTRVHPASYLGELMANVPEHGIRH
LDPDTAMSPNTMKAALRSAGAGVLATDLVLKGEVESAFCAVRPPGHHAEKAKAMGFCFLNNVAIAARHALEAHGLERVAI
VDFDVHHGNGTEDIFRDDPRVMMVSIFQHPFYPYSGVENPPAHMCNVPVPAGTRGDAFRQIVSDIWVPALRNHNPQAIFV
SAGFDAHYEDDMGSLGLVESDYVWATQQIKSVAEDCGHKRVISVLEGGYSLSSLARSVVAHIKALADL
>Mature_307_residues
TTTAFITHRECWLHDMGTFHPECPDRLSAINDRLIAAGLDLYLSFYDAPYATEEQVTRVHPASYLGELMANVPEHGIRHL
DPDTAMSPNTMKAALRSAGAGVLATDLVLKGEVESAFCAVRPPGHHAEKAKAMGFCFLNNVAIAARHALEAHGLERVAIV
DFDVHHGNGTEDIFRDDPRVMMVSIFQHPFYPYSGVENPPAHMCNVPVPAGTRGDAFRQIVSDIWVPALRNHNPQAIFVS
AGFDAHYEDDMGSLGLVESDYVWATQQIKSVAEDCGHKRVISVLEGGYSLSSLARSVVAHIKALADL

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI20070354, Length=324, Percent_Identity=34.2592592592593, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI13128864, Length=315, Percent_Identity=36.1904761904762, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI226529806, Length=316, Percent_Identity=33.5443037974684, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI17158039, Length=331, Percent_Identity=30.8157099697885, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI30795204, Length=331, Percent_Identity=30.8157099697885, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI30795202, Length=331, Percent_Identity=30.8157099697885, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI62750349, Length=344, Percent_Identity=29.9418604651163, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI62750347, Length=344, Percent_Identity=29.9418604651163, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI153085395, Length=326, Percent_Identity=30.0613496932515, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI148539870, Length=329, Percent_Identity=32.2188449848024, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI169234807, Length=329, Percent_Identity=32.2188449848024, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI13128860, Length=320, Percent_Identity=23.75, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI293336691, Length=284, Percent_Identity=25, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI8923769, Length=289, Percent_Identity=25.6055363321799, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI13128862, Length=306, Percent_Identity=23.5294117647059, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI217272877, Length=223, Percent_Identity=28.2511210762332, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI209862883, Length=222, Percent_Identity=27.9279279279279, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI262073088, Length=179, Percent_Identity=27.3743016759777, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI262073092, Length=222, Percent_Identity=27.027027027027, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540334, Length=308, Percent_Identity=34.0909090909091, Blast_Score=150, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI193206283, Length=308, Percent_Identity=34.0909090909091, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17540332, Length=308, Percent_Identity=34.0909090909091, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI25154020, Length=297, Percent_Identity=29.6296296296296, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI25154022, Length=307, Percent_Identity=28.6644951140065, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI193209491, Length=339, Percent_Identity=29.7935103244838, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17534739, Length=311, Percent_Identity=27.3311897106109, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17537347, Length=304, Percent_Identity=30.2631578947368, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17508561, Length=303, Percent_Identity=25.4125412541254, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561978, Length=295, Percent_Identity=24.7457627118644, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324307, Length=321, Percent_Identity=32.0872274143302, Blast_Score=136, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6325141, Length=368, Percent_Identity=25.5434782608696, Blast_Score=89, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6323999, Length=297, Percent_Identity=24.5791245791246, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6321244, Length=310, Percent_Identity=22.9032258064516, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325325, Length=126, Percent_Identity=30.1587301587302, Blast_Score=75, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24642146, Length=315, Percent_Identity=34.9206349206349, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24642142, Length=315, Percent_Identity=34.9206349206349, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24642144, Length=315, Percent_Identity=34.9206349206349, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI281360899, Length=315, Percent_Identity=34.9206349206349, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24641720, Length=338, Percent_Identity=30.1775147928994, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281360801, Length=338, Percent_Identity=29.8816568047337, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281360799, Length=338, Percent_Identity=29.8816568047337, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24657891, Length=310, Percent_Identity=25.4838709677419, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644244, Length=318, Percent_Identity=24.5283018867925, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33682; Mature: 33551

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTAFITHRECWLHDMGTFHPECPDRLSAINDRLIAAGLDLYLSFYDAPYATEEQVTRV
CCCEEEEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
HPASYLGELMANVPEHGIRHLDPDTAMSPNTMKAALRSAGAGVLATDLVLKGEVESAFCA
CHHHHHHHHHHHCHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHEEEECCCCCCEEE
VRPPGHHAEKAKAMGFCFLNNVAIAARHALEAHGLERVAIVDFDVHHGNGTEDIFRDDPR
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHCCCCH
VMMVSIFQHPFYPYSGVENPPAHMCNVPVPAGTRGDAFRQIVSDIWVPALRNHNPQAIFV
HHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEE
SAGFDAHYEDDMGSLGLVESDYVWATQQIKSVAEDCGHKRVISVLEGGYSLSSLARSVVA
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHH
HIKALADL
HHHHHHCC
>Mature Secondary Structure 
TTTAFITHRECWLHDMGTFHPECPDRLSAINDRLIAAGLDLYLSFYDAPYATEEQVTRV
CCEEEEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
HPASYLGELMANVPEHGIRHLDPDTAMSPNTMKAALRSAGAGVLATDLVLKGEVESAFCA
CHHHHHHHHHHHCHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHEEEECCCCCCEEE
VRPPGHHAEKAKAMGFCFLNNVAIAARHALEAHGLERVAIVDFDVHHGNGTEDIFRDDPR
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHCCCCH
VMMVSIFQHPFYPYSGVENPPAHMCNVPVPAGTRGDAFRQIVSDIWVPALRNHNPQAIFV
HHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEE
SAGFDAHYEDDMGSLGLVESDYVWATQQIKSVAEDCGHKRVISVLEGGYSLSSLARSVVA
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHH
HIKALADL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]