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The map label for this gene is plsC [H]

Identifier: 119897079

GI number: 119897079

Start: 846695

End: 847453

Strand: Direct

Name: plsC [H]

Synonym: azo0788

Alternate gene names: 119897079

Gene position: 846695-847453 (Clockwise)

Preceding gene: 119897078

Following gene: 119897086

Centisome position: 19.35

GC content: 68.51

Gene sequence:

>759_bases
GTGATTCTGCTGCGTTCCCTGTTGTTCGCCATCGTGCTCGCGGTGGTCACCCCGCCGTACGCCATTCTCGGGATGCTGAT
GTTCCCGTTCTCCCCGCATCTGCGCCACCGCGTCATCACCTCGTGGGCACCGCTGGTGATGTGGTTCGTGCGCCACCTGC
TCGGCATCCGCTACCGCGTGGTCGGTGCCGAGAACATCCCGGCGGGGCCGGCCGTGATCCTGTCCAAGCACCAGTCGGCA
TGGGAGACCATGGCGCTGCAGGTGATCTTTCCGCCGCTGTGCTTCGTGTTGAAGCGCGAGCTGCTGAAGGTGCCGTTCTT
CGGCTGGGGCCTGGCGGCGATTCCCGGCATTGCGATCGACCGCGCCGCCGGCAAGGACGCGCTGGCGCAGGTGGTGGAGC
AGGGCCGGGCGCGCCTGAAGGAAGGCTTCTGGGTGGTGGTGTTCCCGGAAGGCACGCGGGTGGCCCCGGGCACGGCGCGG
CGCTACAAGGTCGGGGGCGCCTGGCTGGCCAAACGGGCCGGCGTGCCGGTGGTTCCGGTGGCGCACAACGCCGGCGAGTT
CTGGCGCCGCAATGCCTTCCTCAAGCATCCGGGCGAGATCACGGTCAGCATCGGCCCGGCGATCGAGGTCAAGGGCGTCA
AGGCGGAAGAGATCAACCGCCGTGCCGAAGAATGGGTGGAGGGCGAGATGCGCCGCCTGTTCCCGCATCACTACACCGGT
GACGCGCCGACGCTGCTGCCCGAAGTGGATGCCGGCTGA

Upstream 100 bases:

>100_bases
AGACCCGCGAGGATCCCGCGCTGCCCGACAACGCCCTCATCTACCCCGACCTCGCCTCCGTGGTCGCCGACCTCACCGCC
TGAAGGACCTCGATCTCAAC

Downstream 100 bases:

>100_bases
ATCGGCGCTCCGCTATCGAACAAAAAAAAGCCCCGCATGAGCGGGGCTTTTTTTCGTCCGGCGGAGCCGGATGCGGCGTC
AGCCGACCTTAGGCAACCTT

Product: acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MILLRSLLFAIVLAVVTPPYAILGMLMFPFSPHLRHRVITSWAPLVMWFVRHLLGIRYRVVGAENIPAGPAVILSKHQSA
WETMALQVIFPPLCFVLKRELLKVPFFGWGLAAIPGIAIDRAAGKDALAQVVEQGRARLKEGFWVVVFPEGTRVAPGTAR
RYKVGGAWLAKRAGVPVVPVAHNAGEFWRRNAFLKHPGEITVSIGPAIEVKGVKAEEINRRAEEWVEGEMRRLFPHHYTG
DAPTLLPEVDAG

Sequences:

>Translated_252_residues
MILLRSLLFAIVLAVVTPPYAILGMLMFPFSPHLRHRVITSWAPLVMWFVRHLLGIRYRVVGAENIPAGPAVILSKHQSA
WETMALQVIFPPLCFVLKRELLKVPFFGWGLAAIPGIAIDRAAGKDALAQVVEQGRARLKEGFWVVVFPEGTRVAPGTAR
RYKVGGAWLAKRAGVPVVPVAHNAGEFWRRNAFLKHPGEITVSIGPAIEVKGVKAEEINRRAEEWVEGEMRRLFPHHYTG
DAPTLLPEVDAG
>Mature_252_residues
MILLRSLLFAIVLAVVTPPYAILGMLMFPFSPHLRHRVITSWAPLVMWFVRHLLGIRYRVVGAENIPAGPAVILSKHQSA
WETMALQVIFPPLCFVLKRELLKVPFFGWGLAAIPGIAIDRAAGKDALAQVVEQGRARLKEGFWVVVFPEGTRVAPGTAR
RYKVGGAWLAKRAGVPVVPVAHNAGEFWRRNAFLKHPGEITVSIGPAIEVKGVKAEEINRRAEEWVEGEMRRLFPHHYTG
DAPTLLPEVDAG

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI6041665, Length=196, Percent_Identity=32.1428571428571, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI5453718, Length=183, Percent_Identity=30.0546448087432, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI15100175, Length=183, Percent_Identity=30.0546448087432, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17564032, Length=173, Percent_Identity=31.2138728323699, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6320151, Length=181, Percent_Identity=30.3867403314917, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281364648, Length=184, Percent_Identity=28.2608695652174, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582856, Length=184, Percent_Identity=28.2608695652174, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582854, Length=184, Percent_Identity=28.2608695652174, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27925; Mature: 27925

Theoretical pI: Translated: 10.71; Mature: 10.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLRSLLFAIVLAVVTPPYAILGMLMFPFSPHLRHRVITSWAPLVMWFVRHLLGIRYRV
CHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
VGAENIPAGPAVILSKHQSAWETMALQVIFPPLCFVLKRELLKVPFFGWGLAAIPGIAID
EECCCCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEE
RAAGKDALAQVVEQGRARLKEGFWVVVFPEGTRVAPGTARRYKVGGAWLAKRAGVPVVPV
CCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEECCCCCCEEECCCHHHHHHCCCCEEEE
AHNAGEFWRRNAFLKHPGEITVSIGPAIEVKGVKAEEINRRAEEWVEGEMRRLFPHHYTG
CCCCHHHHHHCCCCCCCCEEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
DAPTLLPEVDAG
CCCCCCCCCCCC
>Mature Secondary Structure
MILLRSLLFAIVLAVVTPPYAILGMLMFPFSPHLRHRVITSWAPLVMWFVRHLLGIRYRV
CHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
VGAENIPAGPAVILSKHQSAWETMALQVIFPPLCFVLKRELLKVPFFGWGLAAIPGIAID
EECCCCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEE
RAAGKDALAQVVEQGRARLKEGFWVVVFPEGTRVAPGTARRYKVGGAWLAKRAGVPVVPV
CCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEECCCCCCEEECCCHHHHHHCCCCEEEE
AHNAGEFWRRNAFLKHPGEITVSIGPAIEVKGVKAEEINRRAEEWVEGEMRRLFPHHYTG
CCCCHHHHHHCCCCCCCCEEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
DAPTLLPEVDAG
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685; 7812434 [H]