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The map label for this gene is gmhB [H]

Identifier: 119897078

GI number: 119897078

Start: 846144

End: 846677

Strand: Direct

Name: gmhB [H]

Synonym: azo0787

Alternate gene names: 119897078

Gene position: 846144-846677 (Clockwise)

Preceding gene: 119897077

Following gene: 119897079

Centisome position: 19.34

GC content: 66.1

Gene sequence:

>534_bases
GTGAAGCTCATCATTCTCGACCGCGACGGCGTCATCAACTACGACTCCGACCAGTTCATCAAGTCGCCGGAAGAGTGGAA
GCCGATTCCCGGCTCGCTCGAGGCGATCGCCAAGCTCAACCAATGGGGTTGGCGCGTCGTGGTGGCGTCCAACCAGTCGG
GCGTCGGCCGCGGCCTGTTCGGCATGGATACGCTAAACGCGATCAATGAAAAGATGGTGAAGAGCCTCGCGCAGGTCGGC
GGGCGGCTCGACGCGATCTTCTTCTGTCCGCACGCGGCGGACTCCACCTGTGAATGCCGCAAGCCCAAGCCGGGCCTGTT
CCTGCAGATCGCCGCGCGCTTCAACGCCGATCTGGCAGGGGTGCCCTGTGTGGGCGACAGCCTGCGCGACCTGCAGGCCG
GCGCCGCGGTCGGCTGTCAGCCCTATCTCGTGCTGACCGGCAAGGGACTCAAGACCCGCGAGGATCCCGCGCTGCCCGAC
AACGCCCTCATCTACCCCGACCTCGCCTCCGTGGTCGCCGACCTCACCGCCTGA

Upstream 100 bases:

>100_bases
CTGGCCGGCCTGATGAACCAGGTCGCCGACATTTCCCGCCTGTCGGCCTGACCGCCACGGCCCGGCGACCGCCGGGCCGG
CCTTCCCGTCCGGAGCCCCT

Downstream 100 bases:

>100_bases
AGGACCTCGATCTCAACGTGATTCTGCTGCGTTCCCTGTTGTTCGCCATCGTGCTCGCGGTGGTCACCCCGCCGTACGCC
ATTCTCGGGATGCTGATGTT

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MKLIILDRDGVINYDSDQFIKSPEEWKPIPGSLEAIAKLNQWGWRVVVASNQSGVGRGLFGMDTLNAINEKMVKSLAQVG
GRLDAIFFCPHAADSTCECRKPKPGLFLQIAARFNADLAGVPCVGDSLRDLQAGAAVGCQPYLVLTGKGLKTREDPALPD
NALIYPDLASVVADLTA

Sequences:

>Translated_177_residues
MKLIILDRDGVINYDSDQFIKSPEEWKPIPGSLEAIAKLNQWGWRVVVASNQSGVGRGLFGMDTLNAINEKMVKSLAQVG
GRLDAIFFCPHAADSTCECRKPKPGLFLQIAARFNADLAGVPCVGDSLRDLQAGAAVGCQPYLVLTGKGLKTREDPALPD
NALIYPDLASVVADLTA
>Mature_177_residues
MKLIILDRDGVINYDSDQFIKSPEEWKPIPGSLEAIAKLNQWGWRVVVASNQSGVGRGLFGMDTLNAINEKMVKSLAQVG
GRLDAIFFCPHAADSTCECRKPKPGLFLQIAARFNADLAGVPCVGDSLRDLQAGAAVGCQPYLVLTGKGLKTREDPALPD
NALIYPDLASVVADLTA

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=154, Percent_Identity=38.3116883116883, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI87082027, Length=143, Percent_Identity=28.6713286713287, Blast_Score=70, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 18984; Mature: 18984

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIILDRDGVINYDSDQFIKSPEEWKPIPGSLEAIAKLNQWGWRVVVASNQSGVGRGLF
CEEEEECCCCEEECCCHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCC
GMDTLNAINEKMVKSLAQVGGRLDAIFFCPHAADSTCECRKPKPGLFLQIAARFNADLAG
CHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCC
VPCVGDSLRDLQAGAAVGCQPYLVLTGKGLKTREDPALPDNALIYPDLASVVADLTA
CCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEECCCHHHHHHHHCC
>Mature Secondary Structure
MKLIILDRDGVINYDSDQFIKSPEEWKPIPGSLEAIAKLNQWGWRVVVASNQSGVGRGLF
CEEEEECCCCEEECCCHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCC
GMDTLNAINEKMVKSLAQVGGRLDAIFFCPHAADSTCECRKPKPGLFLQIAARFNADLAG
CHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCC
VPCVGDSLRDLQAGAAVGCQPYLVLTGKGLKTREDPALPDNALIYPDLASVVADLTA
CCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 12101286 [H]