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The map label for this gene is dctB1 [H]

Identifier: 119896739

GI number: 119896739

Start: 476453

End: 478414

Strand: Reverse

Name: dctB1 [H]

Synonym: azo0448

Alternate gene names: 119896739

Gene position: 478414-476453 (Counterclockwise)

Preceding gene: 119896740

Following gene: 119896738

Centisome position: 10.93

GC content: 72.07

Gene sequence:

>1962_bases
GTGACCGCCGCATCGTCGCCTTCCGCGAAAGCTGACTCCGCGGCCGAGGCGGTTCCCCGCCCGGCGCCGGAGCGTCCGCG
GCCGGGCCACGGGCCGCTGCTCGCCGCGCTGGCGGTGCTGCTGGTCAGCCTGGCCGGCTTCGGCGGCTACCGCCTGGGCG
AAGGGCTGGGCATGCGCGCGCTGCAGGTGGAAGCCAGCCACCGCCTCGACCTCGGCGCCGCCGCGATCGACGGCGTGGTC
AACCGCTATGCCCACATCCCCGCCACCATCGAACTCTCACCCGAGGTCCTCGCGCTGCTGCGCGCGCCCGACAGCGAGGC
GCGCGCAGCAGCCGCCAACCGCTATCTGGAACGGCTCAACGGCCACATCGGCAGCATCGCGCTGTTCGTGCTCGACCGCC
GCGGCGAGGTGCGCGCGGCCAGCAACTGGGCCCACGGCGACAGCTTCATCGGCGAAGACCTCAGCTTCCGGCCGTATTTC
CAGCGCGCGATCGCCGGCCAGGCCGGGCGCCACTTCGCGATCGGCACCACGCGCGGCGACCCGGGCTACTTCGTCTCGCA
TCCGATCCGCGACGGCAGCGAGATCATCGGCGTCGCGGTCATCAAGATTCCGCTGGGCGGGCTGGAGGAGACCTGGCTGT
CGCTCGGCACCCCGGCGCTGATCAGCGACGAGAACGGCGTCGTCATCCTGACCGCGGTGCCGGGCTGGCTGTACCGCTCG
CTGGCGCCGCTGTCCGCCGCCACCGTGGCCGAGATCGAAGCCAACCGGCTCTACAACGGCCGCCCGATCCAGCCGCTGAC
GATCGGGCCCGAGCCAGTGGCGGCGCAGCTGCCGATGGCGGATGAAGACGGCGTGGAACTGCGGCTGGACCGCCGCATCG
CGCTGCCGCCCGAGCTGCCGCGCAACTCCGGCTACTACCTCGCGCAGGGCCGCACGCTGCCCGACACCGGCTGGCGCCTG
CTGGTGTTCTCCGACCTCACCCCGGTGCGCCACCAGGCCGCCAGCCAGGCCGCGCTGGCGCTGGTGGCGGCTGCCTTCGT
GGTGCTGCTGGCGATCTTCATCGCGCAGCGCCGCCGCATCCTGCGCCAGCGCCTGGAGGCGCAGCGCCTGCTCGAACGCT
CCAACGCCGAACTGGAAAACAAGGTCGCGCGCCGCACCCGCGCGCTCACCGAATCCATCGCCCGCCTGCGCAAGGAGATC
GCCGAGCGCCAGCACGCCGAGCAGACCCTGCACGCGGCGCAGGACGAACTGGTGCAGGCCGGCAAGCTGGCGGTGCTCGG
CCAGCTCGCCACCAGCGTCACCCACGAGCTGACCCAGCCGCTGGGCGCGATGCGCACGCTGGCCGGCAACGCGGTGGAAT
TCATGCGCCGCGGCGACCAGGACACGGCCGCGAAGAACCTCGACATCGTCGGCCGCCTCGCCGACCAGATGGCAAGCATC
ATCACCCCGCTGAAGACCTTCGCGCGCAAGTCGCCCGCGGTGCCGGCGGCGGTGGACGTGACGCACGCGGTGGGCAACGC
GCTGTTCCTGCTCGAACAGCGGCTGAAGAGCGCCGACATCACGGTGGACAACGCCTGCGTGGCGGGCGAAGCGATCGCCT
GGTGCGACCAGAACCGGCTGGAGCAGGTGCTGATCAACCTCATCGGCAACGCCATCGACGCGATGCGCGGCCAGCCGCGG
CGCGAACTTTCCATCCATGCGGTGCGCCACGCCGACGGCCGCATCCTGCTGCGCATCGGCGACACCGGCTGCGGCGTGCC
GGAAGCGCTGCGCGGGCGGCTGTTCGAACCCTTCTTCACCACCAAGCCGGCCGGCGAAGGCCTCGGCCTCGGGTTGGCGA
TCTCGCGCGACATCGTGCGCGAATTCGGCGGCGACCTCGACGCCGACAACCGCGCCAGCGGCGGCACCTATTTCACCGTG
TTCCTCAATCCCGCCCCAGCCACGGAGTCCGCCGCGCCATGA

Upstream 100 bases:

>100_bases
GTGCCGGAAACCCTGGAATCCGGGCTCAAGCTCACCGGCTCGGTACTCGAAACCCTGGGCGTGCCCGCCGACGCCGCCAG
CCGCCTGCTGGAGCAGGAAC

Downstream 100 bases:

>100_bases
CCGCCCCACTCCACGTCCTTGTCATCGAAGACGACCCCAACGTGCGGCTCGGCTGCGAGCAGGCGCTGCAGCTCGCGGGC
ATCGCGGTCGACGCGGTCGG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 653; Mature: 652

Protein sequence:

>653_residues
MTAASSPSAKADSAAEAVPRPAPERPRPGHGPLLAALAVLLVSLAGFGGYRLGEGLGMRALQVEASHRLDLGAAAIDGVV
NRYAHIPATIELSPEVLALLRAPDSEARAAAANRYLERLNGHIGSIALFVLDRRGEVRAASNWAHGDSFIGEDLSFRPYF
QRAIAGQAGRHFAIGTTRGDPGYFVSHPIRDGSEIIGVAVIKIPLGGLEETWLSLGTPALISDENGVVILTAVPGWLYRS
LAPLSAATVAEIEANRLYNGRPIQPLTIGPEPVAAQLPMADEDGVELRLDRRIALPPELPRNSGYYLAQGRTLPDTGWRL
LVFSDLTPVRHQAASQAALALVAAAFVVLLAIFIAQRRRILRQRLEAQRLLERSNAELENKVARRTRALTESIARLRKEI
AERQHAEQTLHAAQDELVQAGKLAVLGQLATSVTHELTQPLGAMRTLAGNAVEFMRRGDQDTAAKNLDIVGRLADQMASI
ITPLKTFARKSPAVPAAVDVTHAVGNALFLLEQRLKSADITVDNACVAGEAIAWCDQNRLEQVLINLIGNAIDAMRGQPR
RELSIHAVRHADGRILLRIGDTGCGVPEALRGRLFEPFFTTKPAGEGLGLGLAISRDIVREFGGDLDADNRASGGTYFTV
FLNPAPATESAAP

Sequences:

>Translated_653_residues
MTAASSPSAKADSAAEAVPRPAPERPRPGHGPLLAALAVLLVSLAGFGGYRLGEGLGMRALQVEASHRLDLGAAAIDGVV
NRYAHIPATIELSPEVLALLRAPDSEARAAAANRYLERLNGHIGSIALFVLDRRGEVRAASNWAHGDSFIGEDLSFRPYF
QRAIAGQAGRHFAIGTTRGDPGYFVSHPIRDGSEIIGVAVIKIPLGGLEETWLSLGTPALISDENGVVILTAVPGWLYRS
LAPLSAATVAEIEANRLYNGRPIQPLTIGPEPVAAQLPMADEDGVELRLDRRIALPPELPRNSGYYLAQGRTLPDTGWRL
LVFSDLTPVRHQAASQAALALVAAAFVVLLAIFIAQRRRILRQRLEAQRLLERSNAELENKVARRTRALTESIARLRKEI
AERQHAEQTLHAAQDELVQAGKLAVLGQLATSVTHELTQPLGAMRTLAGNAVEFMRRGDQDTAAKNLDIVGRLADQMASI
ITPLKTFARKSPAVPAAVDVTHAVGNALFLLEQRLKSADITVDNACVAGEAIAWCDQNRLEQVLINLIGNAIDAMRGQPR
RELSIHAVRHADGRILLRIGDTGCGVPEALRGRLFEPFFTTKPAGEGLGLGLAISRDIVREFGGDLDADNRASGGTYFTV
FLNPAPATESAAP
>Mature_652_residues
TAASSPSAKADSAAEAVPRPAPERPRPGHGPLLAALAVLLVSLAGFGGYRLGEGLGMRALQVEASHRLDLGAAAIDGVVN
RYAHIPATIELSPEVLALLRAPDSEARAAAANRYLERLNGHIGSIALFVLDRRGEVRAASNWAHGDSFIGEDLSFRPYFQ
RAIAGQAGRHFAIGTTRGDPGYFVSHPIRDGSEIIGVAVIKIPLGGLEETWLSLGTPALISDENGVVILTAVPGWLYRSL
APLSAATVAEIEANRLYNGRPIQPLTIGPEPVAAQLPMADEDGVELRLDRRIALPPELPRNSGYYLAQGRTLPDTGWRLL
VFSDLTPVRHQAASQAALALVAAAFVVLLAIFIAQRRRILRQRLEAQRLLERSNAELENKVARRTRALTESIARLRKEIA
ERQHAEQTLHAAQDELVQAGKLAVLGQLATSVTHELTQPLGAMRTLAGNAVEFMRRGDQDTAAKNLDIVGRLADQMASII
TPLKTFARKSPAVPAAVDVTHAVGNALFLLEQRLKSADITVDNACVAGEAIAWCDQNRLEQVLINLIGNAIDAMRGQPRR
ELSIHAVRHADGRILLRIGDTGCGVPEALRGRLFEPFFTTKPAGEGLGLGLAISRDIVREFGGDLDADNRASGGTYFTVF
LNPAPATESAAP

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=239, Percent_Identity=30.9623430962343, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=31.304347826087, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1789149, Length=279, Percent_Identity=24.3727598566308, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69957; Mature: 69826

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAASSPSAKADSAAEAVPRPAPERPRPGHGPLLAALAVLLVSLAGFGGYRLGEGLGMRA
CCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
LQVEASHRLDLGAAAIDGVVNRYAHIPATIELSPEVLALLRAPDSEARAAAANRYLERLN
EEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHC
GHIGSIALFVLDRRGEVRAASNWAHGDSFIGEDLSFRPYFQRAIAGQAGRHFAIGTTRGD
CCCCEEEEEEEECCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCC
PGYFVSHPIRDGSEIIGVAVIKIPLGGLEETWLSLGTPALISDENGVVILTAVPGWLYRS
CCCEECCCCCCCCCEEEEEEEEECCCCHHHHHHHCCCCEEEECCCCEEEEECCCHHHHHH
LAPLSAATVAEIEANRLYNGRPIQPLTIGPEPVAAQLPMADEDGVELRLDRRIALPPELP
HCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCEEECCCCCCCCCEEEECCEECCCCCCC
RNSGYYLAQGRTLPDTGWRLLVFSDLTPVRHQAASQAALALVAAAFVVLLAIFIAQRRRI
CCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRQRLEAQRLLERSNAELENKVARRTRALTESIARLRKEIAERQHAEQTLHAAQDELVQA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKLAVLGQLATSVTHELTQPLGAMRTLAGNAVEFMRRGDQDTAAKNLDIVGRLADQMASI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ITPLKTFARKSPAVPAAVDVTHAVGNALFLLEQRLKSADITVDNACVAGEAIAWCDQNRL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHCCCHHHHHHHHHH
EQVLINLIGNAIDAMRGQPRRELSIHAVRHADGRILLRIGDTGCGVPEALRGRLFEPFFT
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEECCCCCCCHHHHHCCCCCCCCC
TKPAGEGLGLGLAISRDIVREFGGDLDADNRASGGTYFTVFLNPAPATESAAP
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TAASSPSAKADSAAEAVPRPAPERPRPGHGPLLAALAVLLVSLAGFGGYRLGEGLGMRA
CCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
LQVEASHRLDLGAAAIDGVVNRYAHIPATIELSPEVLALLRAPDSEARAAAANRYLERLN
EEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHC
GHIGSIALFVLDRRGEVRAASNWAHGDSFIGEDLSFRPYFQRAIAGQAGRHFAIGTTRGD
CCCCEEEEEEEECCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCC
PGYFVSHPIRDGSEIIGVAVIKIPLGGLEETWLSLGTPALISDENGVVILTAVPGWLYRS
CCCEECCCCCCCCCEEEEEEEEECCCCHHHHHHHCCCCEEEECCCCEEEEECCCHHHHHH
LAPLSAATVAEIEANRLYNGRPIQPLTIGPEPVAAQLPMADEDGVELRLDRRIALPPELP
HCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCEEECCCCCCCCCEEEECCEECCCCCCC
RNSGYYLAQGRTLPDTGWRLLVFSDLTPVRHQAASQAALALVAAAFVVLLAIFIAQRRRI
CCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRQRLEAQRLLERSNAELENKVARRTRALTESIARLRKEIAERQHAEQTLHAAQDELVQA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKLAVLGQLATSVTHELTQPLGAMRTLAGNAVEFMRRGDQDTAAKNLDIVGRLADQMASI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ITPLKTFARKSPAVPAAVDVTHAVGNALFLLEQRLKSADITVDNACVAGEAIAWCDQNRL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHCCCHHHHHHHHHH
EQVLINLIGNAIDAMRGQPRRELSIHAVRHADGRILLRIGDTGCGVPEALRGRLFEPFFT
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEECCCCCCCHHHHHCCCCCCCCC
TKPAGEGLGLGLAISRDIVREFGGDLDADNRASGGTYFTVFLNPAPATESAAP
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3671068 [H]