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The map label for this gene is dctD1 [H]

Identifier: 119896738

GI number: 119896738

Start: 475122

End: 476456

Strand: Reverse

Name: dctD1 [H]

Synonym: azo0447

Alternate gene names: 119896738

Gene position: 476456-475122 (Counterclockwise)

Preceding gene: 119896739

Following gene: 119896733

Centisome position: 10.89

GC content: 71.01

Gene sequence:

>1335_bases
ATGACCGCCCCACTCCACGTCCTTGTCATCGAAGACGACCCCAACGTGCGGCTCGGCTGCGAGCAGGCGCTGCAGCTCGC
GGGCATCGCGGTCGACGCGGTCGGCTCGGCCGAGGCCGGGCTGGCCAAGCTTGGCGCCGGCTTTCCCGGCATCGTCGTCA
CCGACATGCGCCTGCCCGGCGCCGACGGCCTCGCCGTGGTGCGGCGCGCGCGCGAACTCGACCCCGACCTGCCGGTGATC
ATGATCACCGGCCACGGCGACGTCACGCTGGCGGTGGAGGCGATGCGCAGCGGCGCCTACGACTTCATCCAGAAGCCGTT
CGCGCCCGACCTGCTGGTCGAAGTGGTGCGGCGCGCGCTCGACAAGCGCGCGCTGGCGCTGGAAGTGGTGGAACTGCGCC
GCCGCCTGGAGCAGCGCGACGGGCTGGACGCCGCGCTGATCGGCCGTTCGCCGCAGATGGAGCGGCTGCGCCGGCTGATC
CTGGACGTGGCCGGGCAGACAGTGGACGTGCTGATCCACGGCGAGACCGGCACCGGCAAGGAACTGGTGGCGCGCTGCCT
GCACGACCGTGGCCCGCGCCGCAAGGCCAACTTCGTCGCGCTCAACTGCGGCGGCCTGCCCGACAACCTGCTCGACAGCG
AACTCTTCGGCCACGAGGCCGGCGCCTTCACCGGCGCGCAGAAGCGCCGCGTCGGCAAGATCGAGCACGCCAGCGGCGGC
ACCCTGTTCCTCGACGAGTTGGAGAGCATGCCGATGGCCGTGCAGATCAAGCTGCTGCGGGTGCTGCAGGAGCGCGTGAT
CGAACGGCTCGGCTCCAACCAGCTGCTGCCGGTCGATACCCGCGTCGTCGCCGCCACCAAGGACGACCTGCTCGAACTCG
CCAACCAGGGGAAATTCCGCGCCGACCTCTACTACCGGCTCAACGTCGTCACCATCGAACTGCCGCCGCTGCGCGAACGG
CGCGAGGACATCCCGCTGCTGCTCGAGCACTTCCTGCTGCAGGCGGCGCAGCGCTTCGAGCGCCCGCTGCCGGCGGTGAG
CCCGGAGCACATGAGCCGGCTGATGGCGCACGGCTGGCCTGGCAACGTGCGCGAACTGCGCAATGTGGCCGACTGCCTGG
TGCTGGGCGTCGCCAACGCGGTGCTCGGCACCGCCGGCAGCGTGGCCACCCTGTCGCTGGCCGAGCAGGTGGAACACTTC
GAACGCAGCCTGATCGACGCCGAACTGCGCCGTCAGGCGGGCAACCTCAGCCGCGCCGCCGAAGCGCTGCACGTGGCCAA
GACCACGCTGCACGACAAGATCCGCAAGTACGGCCTGGGCGCGCGCGACGCCTGA

Upstream 100 bases:

>100_bases
GCGAATTCGGCGGCGACCTCGACGCCGACAACCGCGCCAGCGGCGGCACCTATTTCACCGTGTTCCTCAATCCCGCCCCA
GCCACGGAGTCCGCCGCGCC

Downstream 100 bases:

>100_bases
GGGCCGCGCTAGCCGGCGACGCGGAACACCTCGCCGTCGCCGACCACGCACACGGTGTCGAGCGGCCCGGGCCACACCTC
CGCACTGCCGGTGAATGCGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MTAPLHVLVIEDDPNVRLGCEQALQLAGIAVDAVGSAEAGLAKLGAGFPGIVVTDMRLPGADGLAVVRRARELDPDLPVI
MITGHGDVTLAVEAMRSGAYDFIQKPFAPDLLVEVVRRALDKRALALEVVELRRRLEQRDGLDAALIGRSPQMERLRRLI
LDVAGQTVDVLIHGETGTGKELVARCLHDRGPRRKANFVALNCGGLPDNLLDSELFGHEAGAFTGAQKRRVGKIEHASGG
TLFLDELESMPMAVQIKLLRVLQERVIERLGSNQLLPVDTRVVAATKDDLLELANQGKFRADLYYRLNVVTIELPPLRER
REDIPLLLEHFLLQAAQRFERPLPAVSPEHMSRLMAHGWPGNVRELRNVADCLVLGVANAVLGTAGSVATLSLAEQVEHF
ERSLIDAELRRQAGNLSRAAEALHVAKTTLHDKIRKYGLGARDA

Sequences:

>Translated_444_residues
MTAPLHVLVIEDDPNVRLGCEQALQLAGIAVDAVGSAEAGLAKLGAGFPGIVVTDMRLPGADGLAVVRRARELDPDLPVI
MITGHGDVTLAVEAMRSGAYDFIQKPFAPDLLVEVVRRALDKRALALEVVELRRRLEQRDGLDAALIGRSPQMERLRRLI
LDVAGQTVDVLIHGETGTGKELVARCLHDRGPRRKANFVALNCGGLPDNLLDSELFGHEAGAFTGAQKRRVGKIEHASGG
TLFLDELESMPMAVQIKLLRVLQERVIERLGSNQLLPVDTRVVAATKDDLLELANQGKFRADLYYRLNVVTIELPPLRER
REDIPLLLEHFLLQAAQRFERPLPAVSPEHMSRLMAHGWPGNVRELRNVADCLVLGVANAVLGTAGSVATLSLAEQVEHF
ERSLIDAELRRQAGNLSRAAEALHVAKTTLHDKIRKYGLGARDA
>Mature_443_residues
TAPLHVLVIEDDPNVRLGCEQALQLAGIAVDAVGSAEAGLAKLGAGFPGIVVTDMRLPGADGLAVVRRARELDPDLPVIM
ITGHGDVTLAVEAMRSGAYDFIQKPFAPDLLVEVVRRALDKRALALEVVELRRRLEQRDGLDAALIGRSPQMERLRRLIL
DVAGQTVDVLIHGETGTGKELVARCLHDRGPRRKANFVALNCGGLPDNLLDSELFGHEAGAFTGAQKRRVGKIEHASGGT
LFLDELESMPMAVQIKLLRVLQERVIERLGSNQLLPVDTRVVAATKDDLLELANQGKFRADLYYRLNVVTIELPPLRERR
EDIPLLLEHFLLQAAQRFERPLPAVSPEHMSRLMAHGWPGNVRELRNVADCLVLGVANAVLGTAGSVATLSLAEQVEHFE
RSLIDAELRRQAGNLSRAAEALHVAKTTLHDKIRKYGLGARDA

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=461, Percent_Identity=39.0455531453362, Blast_Score=324, Evalue=7e-90,
Organism=Escherichia coli, GI1790299, Length=468, Percent_Identity=38.4615384615385, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI1788905, Length=448, Percent_Identity=38.6160714285714, Blast_Score=301, Evalue=5e-83,
Organism=Escherichia coli, GI1790437, Length=448, Percent_Identity=38.3928571428571, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI87082117, Length=248, Percent_Identity=50.4032258064516, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1789087, Length=276, Percent_Identity=47.1014492753623, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1789233, Length=319, Percent_Identity=40.1253918495298, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI87081872, Length=203, Percent_Identity=53.6945812807882, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1786524, Length=243, Percent_Identity=46.0905349794239, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI87082152, Length=316, Percent_Identity=41.1392405063291, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1787583, Length=314, Percent_Identity=35.031847133758, Blast_Score=184, Evalue=9e-48,
Organism=Escherichia coli, GI87081858, Length=305, Percent_Identity=31.4754098360656, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1789828, Length=248, Percent_Identity=35.4838709677419, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1789809, Length=124, Percent_Identity=33.8709677419355, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787375, Length=103, Percent_Identity=34.9514563106796, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790552, Length=104, Percent_Identity=35.5769230769231, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789402, Length=131, Percent_Identity=34.3511450381679, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 48486; Mature: 48355

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4 ; PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPLHVLVIEDDPNVRLGCEQALQLAGIAVDAVGSAEAGLAKLGAGFPGIVVTDMRLPG
CCCCEEEEEEECCCCCEECHHHHHHHHHHHEECCCCCHHHHHHHCCCCCCEEEEECCCCC
ADGLAVVRRARELDPDLPVIMITGHGDVTLAVEAMRSGAYDFIQKPFAPDLLVEVVRRAL
CCHHHHHHHHHHCCCCCCEEEEECCCCEEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHH
DKRALALEVVELRRRLEQRDGLDAALIGRSPQMERLRRLILDVAGQTVDVLIHGETGTGK
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCH
ELVARCLHDRGPRRKANFVALNCGGLPDNLLDSELFGHEAGAFTGAQKRRVGKIEHASGG
HHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHCCCCEECCCC
TLFLDELESMPMAVQIKLLRVLQERVIERLGSNQLLPVDTRVVAATKDDLLELANQGKFR
EEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEECCHHHHHHHHHCCCEE
ADLYYRLNVVTIELPPLRERREDIPLLLEHFLLQAAQRFERPLPAVSPEHMSRLMAHGWP
EEEEEEEEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
GNVRELRNVADCLVLGVANAVLGTAGSVATLSLAEQVEHFERSLIDAELRRQAGNLSRAA
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
EALHVAKTTLHDKIRKYGLGARDA
HHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TAPLHVLVIEDDPNVRLGCEQALQLAGIAVDAVGSAEAGLAKLGAGFPGIVVTDMRLPG
CCCEEEEEEECCCCCEECHHHHHHHHHHHEECCCCCHHHHHHHCCCCCCEEEEECCCCC
ADGLAVVRRARELDPDLPVIMITGHGDVTLAVEAMRSGAYDFIQKPFAPDLLVEVVRRAL
CCHHHHHHHHHHCCCCCCEEEEECCCCEEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHH
DKRALALEVVELRRRLEQRDGLDAALIGRSPQMERLRRLILDVAGQTVDVLIHGETGTGK
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCH
ELVARCLHDRGPRRKANFVALNCGGLPDNLLDSELFGHEAGAFTGAQKRRVGKIEHASGG
HHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHCCCCEECCCC
TLFLDELESMPMAVQIKLLRVLQERVIERLGSNQLLPVDTRVVAATKDDLLELANQGKFR
EEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEECCHHHHHHHHHCCCEE
ADLYYRLNVVTIELPPLRERREDIPLLLEHFLLQAAQRFERPLPAVSPEHMSRLMAHGWP
EEEEEEEEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
GNVRELRNVADCLVLGVANAVLGTAGSVATLSLAEQVEHFERSLIDAELRRQAGNLSRAA
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
EALHVAKTTLHDKIRKYGLGARDA
HHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]