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The map label for this gene is rocD [H]

Identifier: 119896667

GI number: 119896667

Start: 399721

End: 401841

Strand: Reverse

Name: rocD [H]

Synonym: azo0376

Alternate gene names: 119896667

Gene position: 401841-399721 (Counterclockwise)

Preceding gene: 119896668

Following gene: 119896666

Centisome position: 9.18

GC content: 72.98

Gene sequence:

>2121_bases
ATGAACGTTCCCACCCCGCTGCCCTCCGGGCCGCATGATCGCGTCCACATCGTCGGCGCCGCGTTCGCGCTCGGCGCGCC
GCATGGCGGCAGCGCCGACGGACCCGAAGCGCTGCGCCACGCGATGCTGCCCGAACGGCTGCGGACCACCGGCATCACCG
GCACCTGGCTGGAACCCCTGCGCCCGCTGCGCACCCCGCCACCCGACGCGCCGATGGAAGAACGCCTCGCCGCGGTGGGC
GAGTACTGCGCCCGGCTGGCGGAGCAGATCGCCGGGCTGCCGGAGGACGGCTTTCCGCTCGTGCTCGGTGGCGACCACGC
GGTGGCGATCGGCACCTGGCGCGGCGTTGCCCGCCGCCAGGGCGGCGCGCCGGGGCTGATCTGGATCGATGCCCATCTGG
ACAGCCACACCGACCAATCCACCTGGTCCGGCAACATTCACGGCATGCCGCTGGCCGCACTGCTGGGCGAAGGCGCCCCC
GCGCTGACCGCGATCCCCGGCCCGCGACTCGACCCCGCGCGCGTCTGCATCATCGGCGCGCGCGACTGGGAGCCGGCCGA
GCGCGAACGGCTGGACCGGCTCGGCGTGCGCGTGTTCGACATCGCCGAGGTGCGCGAGCGCGGGCTGCCCACGGTGTTCT
GCGAGGCGCTGACGATCGCGCGCAGCGGCCACGGCCGCGACGGCGGCTTCGGCGTCACGCTCGACCTCGACGCACTCGAC
CCGCTCGCGGTGCCGGCGGTGACCTGCCCCACGCCGGACGGCATCGACCCGCAGCAACTGGTCGATGTCTTCCATACGCT
GCGCAGCTGCGGCGACTTCGTCGGGCTGGAGATCGTCGAATACCGCCCCGACCTCGACCCCGACGGCCACTCCGCCGCGC
TCACCGCGCGCCTCGTCGCCGCCGCGCTCGGCCCGGCGACCTACTGGCTGCGCGAGAAGGAGCGCCGCTTCGGCGCCACC
AACTACGCGCCGATGCCGGTGGTCTTCCACCGCGGCGAAGGCGTATGGCTGTGGGACGTCGAGGGCACGCGCTACCTCGA
CATGATGAGCGCCTATTCGGCGGTCAGCTTCGGCCACGCCAACCCGCGCCTGCTGCGCGCGCTGCAGGACCAGGCGCAGT
TGCTGACGCTGACTTCGCGCTCGTTCTCCAACGACCGCCTGCCGCTGCTGCTGGAAAGGCTGTGCTCGCTGCTCGGCTTC
GAGCGCGCGCTGCCGGTCAATACCGGGCTGGAGGCGGTGGAAACGGCGCTGAAGGCGGCGCGCAAATGGGCTTACATCGT
CAAGGGCGTGCCGCCCGACCGGGCCGAGATCATCGCCTGCGAGGGCAATTTCCACGGCCGCTCGATCACCATCGTCGGGC
TTTCTTCGAAGGAGCAGTACCGCGACGGCTTCGGCCCCTTCCCGCCCGGGCTGCGGCGGGTGCCGTTCGGCGACCCGACC
GCACTCGAAGCGGCGATCACCCCCCACACCGCGGCCTTCCTGGTCGAACCCATCCAGGGCGAAGGCGGCATCATCGTGCC
GCCGCCGGGGTATCTGGCCCACTGCGCCGAAATCTGCCGCCGCCACAACGTGCTGCTGATCGCCGACGAGGTGCAGACCG
GCCTTGGCCGCACCGGCCGCCTGCTCGCCTGCGACCACGACGGCGTGCGGCCCGACGGGCTGATCCTGGGCAAGGCGCTG
GGCGGCGGGCTATTGCCGGTGTCGGCCTTCCTGGCCGACCGCGAGGTGATGGACGTGTTCCGCCCCGGCGACCACGGCTC
CACCTTCGGCGGCAACCCGCTGGGCGCCGCGGTGGCGCTGGAAGTGCTCGACCTGCTCGCCGAAACCCGGCCGTGGGAAG
CCGCCGAGCGCCTCGGCCGGCGCCTGCGCGCGGAGCTGGAAGCCGCCGAGCTGCCCTGCGTGCGCGAAGTGCGCGGGCGC
GGGCTGCTGATCGGGGTGGCGCTGGACCCGGTGAAGGCGCCCGCGCAGCTGGTTGCCGAGTTGCTGCTGGCGCGCGGCAT
CGCCACCCGCGACACCAATGGCAACGTGATCCGGCTGGCGCCGCCGCTGACCATCGACGAAGGCACGCTGGACCGCGCCG
CCGCGATCATCATCGACACCCTCAACCCGCTCGGCCGCTGA

Upstream 100 bases:

>100_bases
CTGAACGTTTCCGCCGCCCCCCGGCTCCAAGCCTTACGCTCAATGCTTATTCGCCCGCGCTAGCGCAACCCGCCGGCAAG
GGCTCGACGGGAGGCACGCC

Downstream 100 bases:

>100_bases
GCGCCGCCACCCGCTGTCGCACAGCTGACAATTCCACCCTCATATGCGCTGCCGGACGCACCACCACGGTGCGCCGGCGG
CGCCATATTGTTCCACCCAA

Product: hypothetical protein

Products: NA

Alternate protein names: OAT; Ornithine--oxo-acid aminotransferase [H]

Number of amino acids: Translated: 706; Mature: 706

Protein sequence:

>706_residues
MNVPTPLPSGPHDRVHIVGAAFALGAPHGGSADGPEALRHAMLPERLRTTGITGTWLEPLRPLRTPPPDAPMEERLAAVG
EYCARLAEQIAGLPEDGFPLVLGGDHAVAIGTWRGVARRQGGAPGLIWIDAHLDSHTDQSTWSGNIHGMPLAALLGEGAP
ALTAIPGPRLDPARVCIIGARDWEPAERERLDRLGVRVFDIAEVRERGLPTVFCEALTIARSGHGRDGGFGVTLDLDALD
PLAVPAVTCPTPDGIDPQQLVDVFHTLRSCGDFVGLEIVEYRPDLDPDGHSAALTARLVAAALGPATYWLREKERRFGAT
NYAPMPVVFHRGEGVWLWDVEGTRYLDMMSAYSAVSFGHANPRLLRALQDQAQLLTLTSRSFSNDRLPLLLERLCSLLGF
ERALPVNTGLEAVETALKAARKWAYIVKGVPPDRAEIIACEGNFHGRSITIVGLSSKEQYRDGFGPFPPGLRRVPFGDPT
ALEAAITPHTAAFLVEPIQGEGGIIVPPPGYLAHCAEICRRHNVLLIADEVQTGLGRTGRLLACDHDGVRPDGLILGKAL
GGGLLPVSAFLADREVMDVFRPGDHGSTFGGNPLGAAVALEVLDLLAETRPWEAAERLGRRLRAELEAAELPCVREVRGR
GLLIGVALDPVKAPAQLVAELLLARGIATRDTNGNVIRLAPPLTIDEGTLDRAAAIIIDTLNPLGR

Sequences:

>Translated_706_residues
MNVPTPLPSGPHDRVHIVGAAFALGAPHGGSADGPEALRHAMLPERLRTTGITGTWLEPLRPLRTPPPDAPMEERLAAVG
EYCARLAEQIAGLPEDGFPLVLGGDHAVAIGTWRGVARRQGGAPGLIWIDAHLDSHTDQSTWSGNIHGMPLAALLGEGAP
ALTAIPGPRLDPARVCIIGARDWEPAERERLDRLGVRVFDIAEVRERGLPTVFCEALTIARSGHGRDGGFGVTLDLDALD
PLAVPAVTCPTPDGIDPQQLVDVFHTLRSCGDFVGLEIVEYRPDLDPDGHSAALTARLVAAALGPATYWLREKERRFGAT
NYAPMPVVFHRGEGVWLWDVEGTRYLDMMSAYSAVSFGHANPRLLRALQDQAQLLTLTSRSFSNDRLPLLLERLCSLLGF
ERALPVNTGLEAVETALKAARKWAYIVKGVPPDRAEIIACEGNFHGRSITIVGLSSKEQYRDGFGPFPPGLRRVPFGDPT
ALEAAITPHTAAFLVEPIQGEGGIIVPPPGYLAHCAEICRRHNVLLIADEVQTGLGRTGRLLACDHDGVRPDGLILGKAL
GGGLLPVSAFLADREVMDVFRPGDHGSTFGGNPLGAAVALEVLDLLAETRPWEAAERLGRRLRAELEAAELPCVREVRGR
GLLIGVALDPVKAPAQLVAELLLARGIATRDTNGNVIRLAPPLTIDEGTLDRAAAIIIDTLNPLGR
>Mature_706_residues
MNVPTPLPSGPHDRVHIVGAAFALGAPHGGSADGPEALRHAMLPERLRTTGITGTWLEPLRPLRTPPPDAPMEERLAAVG
EYCARLAEQIAGLPEDGFPLVLGGDHAVAIGTWRGVARRQGGAPGLIWIDAHLDSHTDQSTWSGNIHGMPLAALLGEGAP
ALTAIPGPRLDPARVCIIGARDWEPAERERLDRLGVRVFDIAEVRERGLPTVFCEALTIARSGHGRDGGFGVTLDLDALD
PLAVPAVTCPTPDGIDPQQLVDVFHTLRSCGDFVGLEIVEYRPDLDPDGHSAALTARLVAAALGPATYWLREKERRFGAT
NYAPMPVVFHRGEGVWLWDVEGTRYLDMMSAYSAVSFGHANPRLLRALQDQAQLLTLTSRSFSNDRLPLLLERLCSLLGF
ERALPVNTGLEAVETALKAARKWAYIVKGVPPDRAEIIACEGNFHGRSITIVGLSSKEQYRDGFGPFPPGLRRVPFGDPT
ALEAAITPHTAAFLVEPIQGEGGIIVPPPGYLAHCAEICRRHNVLLIADEVQTGLGRTGRLLACDHDGVRPDGLILGKAL
GGGLLPVSAFLADREVMDVFRPGDHGSTFGGNPLGAAVALEVLDLLAETRPWEAAERLGRRLRAELEAAELPCVREVRGR
GLLIGVALDPVKAPAQLVAELLLARGIATRDTNGNVIRLAPPLTIDEGTLDRAAAIIIDTLNPLGR

Specific function: Catalyzes the interconversion of ornithine to glutamate semialdehyde [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=418, Percent_Identity=47.3684210526316, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI284507298, Length=298, Percent_Identity=49.6644295302013, Blast_Score=275, Evalue=1e-73,
Organism=Homo sapiens, GI13994255, Length=443, Percent_Identity=28.8939051918736, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI10947139, Length=297, Percent_Identity=32.996632996633, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI24119277, Length=411, Percent_Identity=27.9805352798054, Blast_Score=131, Evalue=3e-30,
Organism=Homo sapiens, GI37574042, Length=423, Percent_Identity=26.9503546099291, Blast_Score=129, Evalue=9e-30,
Organism=Homo sapiens, GI4502215, Length=311, Percent_Identity=30.5466237942122, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI226442705, Length=423, Percent_Identity=26.4775413711584, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI226442709, Length=388, Percent_Identity=27.0618556701031, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1789759, Length=374, Percent_Identity=38.2352941176471, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1788044, Length=381, Percent_Identity=39.1076115485564, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI145693181, Length=375, Percent_Identity=36, Blast_Score=225, Evalue=1e-59,
Organism=Escherichia coli, GI1787560, Length=405, Percent_Identity=34.5679012345679, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1789016, Length=415, Percent_Identity=32.5301204819277, Blast_Score=178, Evalue=8e-46,
Organism=Escherichia coli, GI1786991, Length=403, Percent_Identity=31.0173697270471, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1786349, Length=321, Percent_Identity=29.2834890965732, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI25144271, Length=396, Percent_Identity=45.959595959596, Blast_Score=378, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI25144274, Length=275, Percent_Identity=44, Blast_Score=239, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI71981843, Length=167, Percent_Identity=46.7065868263473, Blast_Score=175, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI32564660, Length=436, Percent_Identity=28.4403669724771, Blast_Score=162, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI71996843, Length=252, Percent_Identity=38.0952380952381, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71992977, Length=437, Percent_Identity=26.5446224256293, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17541228, Length=458, Percent_Identity=24.6724890829694, Blast_Score=94, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323470, Length=412, Percent_Identity=44.4174757281553, Blast_Score=352, Evalue=2e-97,
Organism=Saccharomyces cerevisiae, GI6324432, Length=405, Percent_Identity=32.0987654320988, Blast_Score=187, Evalue=7e-48,
Organism=Saccharomyces cerevisiae, GI6325146, Length=224, Percent_Identity=33.0357142857143, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324386, Length=416, Percent_Identity=24.5192307692308, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI21357415, Length=402, Percent_Identity=47.0149253731343, Blast_Score=370, Evalue=1e-102,
Organism=Drosophila melanogaster, GI28574759, Length=469, Percent_Identity=29.637526652452, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI161085790, Length=449, Percent_Identity=29.6213808463252, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21356575, Length=441, Percent_Identity=28.7981859410431, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24638886, Length=297, Percent_Identity=27.9461279461279, Blast_Score=93, Evalue=7e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.13 [H]

Molecular weight: Translated: 75539; Mature: 75539

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00600 AA_TRANSFER_CLASS_3 ; PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVPTPLPSGPHDRVHIVGAAFALGAPHGGSADGPEALRHAMLPERLRTTGITGTWLEPL
CCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHCHHHHHHCCCCCCCHHHC
RPLRTPPPDAPMEERLAAVGEYCARLAEQIAGLPEDGFPLVLGGDHAVAIGTWRGVARRQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECHHHHHHHC
GGAPGLIWIDAHLDSHTDQSTWSGNIHGMPLAALLGEGAPALTAIPGPRLDPARVCIIGA
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEECCCCCCCCCEEEEEEC
RDWEPAERERLDRLGVRVFDIAEVRERGLPTVFCEALTIARSGHGRDGGFGVTLDLDALD
CCCCHHHHHHHHHHCCEEEEHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCC
PLAVPAVTCPTPDGIDPQQLVDVFHTLRSCGDFVGLEIVEYRPDLDPDGHSAALTARLVA
CCCCCEEECCCCCCCCHHHHHHHHHHHHHHCHHHCCEEEEECCCCCCCCCHHHHHHHHHH
AALGPATYWLREKERRFGATNYAPMPVVFHRGEGVWLWDVEGTRYLDMMSAYSAVSFGHA
HHHCHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHCCCC
NPRLLRALQDQAQLLTLTSRSFSNDRLPLLLERLCSLLGFERALPVNTGLEAVETALKAA
CHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RKWAYIVKGVPPDRAEIIACEGNFHGRSITIVGLSSKEQYRDGFGPFPPGLRRVPFGDPT
HHHEEEECCCCCCCCEEEEECCCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCCC
ALEAAITPHTAAFLVEPIQGEGGIIVPPPGYLAHCAEICRRHNVLLIADEVQTGLGRTGR
CEEEECCCCCEEEEEEEECCCCCEEECCCCHHHHHHHHHHHCCEEEEECCHHHCCCCCCC
LLACDHDGVRPDGLILGKALGGGLLPVSAFLADREVMDVFRPGDHGSTFGGNPLGAAVAL
EEEECCCCCCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
EVLDLLAETRPWEAAERLGRRLRAELEAAELPCVREVRGRGLLIGVALDPVKAPAQLVAE
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEEEEECCCCCHHHHHHH
LLLARGIATRDTNGNVIRLAPPLTIDEGTLDRAAAIIIDTLNPLGR
HHHHCCCCCCCCCCCEEEECCCCEECCCCHHHHHHHEEECCCCCCC
>Mature Secondary Structure
MNVPTPLPSGPHDRVHIVGAAFALGAPHGGSADGPEALRHAMLPERLRTTGITGTWLEPL
CCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHCHHHHHHCCCCCCCHHHC
RPLRTPPPDAPMEERLAAVGEYCARLAEQIAGLPEDGFPLVLGGDHAVAIGTWRGVARRQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECHHHHHHHC
GGAPGLIWIDAHLDSHTDQSTWSGNIHGMPLAALLGEGAPALTAIPGPRLDPARVCIIGA
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEECCCCCCCCCEEEEEEC
RDWEPAERERLDRLGVRVFDIAEVRERGLPTVFCEALTIARSGHGRDGGFGVTLDLDALD
CCCCHHHHHHHHHHCCEEEEHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCC
PLAVPAVTCPTPDGIDPQQLVDVFHTLRSCGDFVGLEIVEYRPDLDPDGHSAALTARLVA
CCCCCEEECCCCCCCCHHHHHHHHHHHHHHCHHHCCEEEEECCCCCCCCCHHHHHHHHHH
AALGPATYWLREKERRFGATNYAPMPVVFHRGEGVWLWDVEGTRYLDMMSAYSAVSFGHA
HHHCHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHCCCC
NPRLLRALQDQAQLLTLTSRSFSNDRLPLLLERLCSLLGFERALPVNTGLEAVETALKAA
CHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RKWAYIVKGVPPDRAEIIACEGNFHGRSITIVGLSSKEQYRDGFGPFPPGLRRVPFGDPT
HHHEEEECCCCCCCCEEEEECCCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCCC
ALEAAITPHTAAFLVEPIQGEGGIIVPPPGYLAHCAEICRRHNVLLIADEVQTGLGRTGR
CEEEECCCCCEEEEEEEECCCCCEEECCCCHHHHHHHHHHHCCEEEEECCHHHCCCCCCC
LLACDHDGVRPDGLILGKALGGGLLPVSAFLADREVMDVFRPGDHGSTFGGNPLGAAVAL
EEEECCCCCCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
EVLDLLAETRPWEAAERLGRRLRAELEAAELPCVREVRGRGLLIGVALDPVKAPAQLVAE
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEEEEECCCCCHHHHHHH
LLLARGIATRDTNGNVIRLAPPLTIDEGTLDRAAAIIIDTLNPLGR
HHHHCCCCCCCCCCCEEEECCCCEECCCCHHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA