Click here to switch to the map view.

The map label for this gene is ycgO [H]

Identifier: 119896666

GI number: 119896666

Start: 398061

End: 399524

Strand: Reverse

Name: ycgO [H]

Synonym: azo0375

Alternate gene names: 119896666

Gene position: 399524-398061 (Counterclockwise)

Preceding gene: 119896667

Following gene: 119896665

Centisome position: 9.13

GC content: 66.67

Gene sequence:

>1464_bases
ATGCTGATCGGCTTCGTCACCGCCTACCTCGTCCTCTCCATCGCCATCGGCCTGTACGCCGCCACGCGGGTCAAGAACTC
CACCGACTATGTCGCCGCCGGCCGCAACCTGCCGCTGTACATCGTCACCGCCACGGTGTTCGCCACCTGGTTCGGCTCCG
AAACCGTGCTCGGTATCTCCGCCACCTTCATCGACGAAGGCTTGCGCGGGCTGTGGTCCGACCCCTTTGGCGCCTCGCTG
TGCCTGATCCTGGCGGGCCTGTTCTTCGCCCGCCCGCTGTACCGCATGAACCTGCTGACGCTGGGCGACTACTACCGCAC
ACGCTACGGCCGCACGGTGGAAGTGCTGTGCTCGCTGGCGATCGTGGTGTCCTACCTCGGCTGGGTGTCGGCGCAGATCA
GTGCGCTCGGGCTGGTGTTCAACATCCTGTCCGAGGGATCGATCTCCGCCGAAACCGGCATGCTGGTCGGCGCGGGCATC
GTGCTCGCCTACACCCTGTTCGGCGGCATGTGGTCGGTGGCGCTGACCGACTTCATGCAGATGGCGATCATCATCGTCGG
CCTCGCCTACATCGCCTGGCTGGTGGGCGACATGGCCGGTGGTGTGGGCGCGGTGGTCGCCCACGCCAACGAGGCCGGCA
AGCTCAACTTCCTGCCCGCCTTCGACGCCAAGGACATCATCGCCTTCACTGCCGGCATCCTGACCATGGGCTTCGGCTCC
ATTCCGCAGCAGGACGTGTTCCAGCGCTTCAACGCCGCGCGTAACGAGCGCATCGCGGTGCAGGGCACGCTGCTCGGCGG
CAGCGGGTATTTCCTGTTCGCCTTCATCCCGCTGTTCATCGCCTACTCCGCCACACTGATCGACCCCGCGCTGGTAGCCA
ACTACCAGGAAAGCGACAGCCAACAGATCCTGCCCCAGCTGATCCTGGAGCACACGCCCCTGTTCGCGCAGGTGCTGTTC
TTCGGCGCGCTGCTGTCCGCGATCATGAGTACCGCGTCGGGCACGCTGCTGGCGCCCTCGGTGACCTTCTCCGAGAACAT
TCTGCGCAGCACCTTCCGCGGCATGAACGACCGCCAGTTCCTGGTGATGACTCGCGTCGTCGTCGTGCTGTTCGCGCTGC
TGGTCACCTGGTACGCGATCCACACGGACGAGAGCATCCACGGGATGGTGGAGAACGCCTACAAGGTCACGCTGGCCACC
GCCTTCGTGCCGCTCGCCTTCGGCCTGTACTGGAAGCGCGCGAGCACCCAGGGCGCGCTGGTATCGATCGTGGCGGGCCT
GGCGGTGTGGGTGCTGCTGGAGATCGTCGCCCCCGAGGCCGACGTGCCGCCGCACTTTGCCGGCATGCTGGCCGGCGTGG
TCGGCATGGTGGTGGGCTCGCTCGCGCCGCAGACCCTGGTGCGCCAGAGCCACGGCCACAGCGCGCACCTCAACATCGGG
GCGCACCCGCAGTCGCGCAACTGA

Upstream 100 bases:

>100_bases
CCAATCAGGTGCTTAGAGGCGATTTTTCGGGCTGCCGGCACGATTCGTTGTTACACTCCCGCGCTCCGGAACCCGCCGGC
CCCGCGCCGGAAAGCTCGCC

Downstream 100 bases:

>100_bases
GCGCGCCCCTTGGGCACGGAAGGCCGGGCCAAGCCCGGCCTTTTTCGTTCACGGCTGCGGCGCCCTCCCCTTGCATGAGG
GTGGAATCGGCGCCGGCGCC

Product: sodium/solute symporter transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MLIGFVTAYLVLSIAIGLYAATRVKNSTDYVAAGRNLPLYIVTATVFATWFGSETVLGISATFIDEGLRGLWSDPFGASL
CLILAGLFFARPLYRMNLLTLGDYYRTRYGRTVEVLCSLAIVVSYLGWVSAQISALGLVFNILSEGSISAETGMLVGAGI
VLAYTLFGGMWSVALTDFMQMAIIIVGLAYIAWLVGDMAGGVGAVVAHANEAGKLNFLPAFDAKDIIAFTAGILTMGFGS
IPQQDVFQRFNAARNERIAVQGTLLGGSGYFLFAFIPLFIAYSATLIDPALVANYQESDSQQILPQLILEHTPLFAQVLF
FGALLSAIMSTASGTLLAPSVTFSENILRSTFRGMNDRQFLVMTRVVVVLFALLVTWYAIHTDESIHGMVENAYKVTLAT
AFVPLAFGLYWKRASTQGALVSIVAGLAVWVLLEIVAPEADVPPHFAGMLAGVVGMVVGSLAPQTLVRQSHGHSAHLNIG
AHPQSRN

Sequences:

>Translated_487_residues
MLIGFVTAYLVLSIAIGLYAATRVKNSTDYVAAGRNLPLYIVTATVFATWFGSETVLGISATFIDEGLRGLWSDPFGASL
CLILAGLFFARPLYRMNLLTLGDYYRTRYGRTVEVLCSLAIVVSYLGWVSAQISALGLVFNILSEGSISAETGMLVGAGI
VLAYTLFGGMWSVALTDFMQMAIIIVGLAYIAWLVGDMAGGVGAVVAHANEAGKLNFLPAFDAKDIIAFTAGILTMGFGS
IPQQDVFQRFNAARNERIAVQGTLLGGSGYFLFAFIPLFIAYSATLIDPALVANYQESDSQQILPQLILEHTPLFAQVLF
FGALLSAIMSTASGTLLAPSVTFSENILRSTFRGMNDRQFLVMTRVVVVLFALLVTWYAIHTDESIHGMVENAYKVTLAT
AFVPLAFGLYWKRASTQGALVSIVAGLAVWVLLEIVAPEADVPPHFAGMLAGVVGMVVGSLAPQTLVRQSHGHSAHLNIG
AHPQSRN
>Mature_487_residues
MLIGFVTAYLVLSIAIGLYAATRVKNSTDYVAAGRNLPLYIVTATVFATWFGSETVLGISATFIDEGLRGLWSDPFGASL
CLILAGLFFARPLYRMNLLTLGDYYRTRYGRTVEVLCSLAIVVSYLGWVSAQISALGLVFNILSEGSISAETGMLVGAGI
VLAYTLFGGMWSVALTDFMQMAIIIVGLAYIAWLVGDMAGGVGAVVAHANEAGKLNFLPAFDAKDIIAFTAGILTMGFGS
IPQQDVFQRFNAARNERIAVQGTLLGGSGYFLFAFIPLFIAYSATLIDPALVANYQESDSQQILPQLILEHTPLFAQVLF
FGALLSAIMSTASGTLLAPSVTFSENILRSTFRGMNDRQFLVMTRVVVVLFALLVTWYAIHTDESIHGMVENAYKVTLAT
AFVPLAFGLYWKRASTQGALVSIVAGLAVWVLLEIVAPEADVPPHFAGMLAGVVGMVVGSLAPQTLVRQSHGHSAHLNIG
AHPQSRN

Specific function: Catalyzes the sodium-dependent uptake of extracellular amino acids [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI11141885, Length=451, Percent_Identity=27.4944567627494, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI4507035, Length=379, Percent_Identity=26.3852242744063, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI109659836, Length=528, Percent_Identity=25, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI109659839, Length=544, Percent_Identity=24.4485294117647, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI167466278, Length=471, Percent_Identity=22.9299363057325, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI310128183, Length=452, Percent_Identity=25.2212389380531, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1787251, Length=522, Percent_Identity=27.2030651340996, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082237, Length=481, Percent_Identity=25.3638253638254, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790503, Length=449, Percent_Identity=21.6035634743875, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17539284, Length=456, Percent_Identity=25.8771929824561, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24648033, Length=437, Percent_Identity=24.9427917620137, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21356865, Length=437, Percent_Identity=24.9427917620137, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28573698, Length=397, Percent_Identity=23.9294710327456, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011851
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 52194; Mature: 52194

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIGFVTAYLVLSIAIGLYAATRVKNSTDYVAAGRNLPLYIVTATVFATWFGSETVLGIS
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEHHHHHHHHHCCCCEEEEEH
ATFIDEGLRGLWSDPFGASLCLILAGLFFARPLYRMNLLTLGDYYRTRYGRTVEVLCSLA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
IVVSYLGWVSAQISALGLVFNILSEGSISAETGMLVGAGIVLAYTLFGGMWSVALTDFMQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAIIIVGLAYIAWLVGDMAGGVGAVVAHANEAGKLNFLPAFDAKDIIAFTAGILTMGFGS
HHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCCCEEEECCCCCHHHHHHHHHHHHHCCCC
IPQQDVFQRFNAARNERIAVQGTLLGGSGYFLFAFIPLFIAYSATLIDPALVANYQESDS
CCHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCH
QQILPQLILEHTPLFAQVLFFGALLSAIMSTASGTLLAPSVTFSENILRSTFRGMNDRQF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCCCCCHH
LVMTRVVVVLFALLVTWYAIHTDESIHGMVENAYKVTLATAFVPLAFGLYWKRASTQGAL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VSIVAGLAVWVLLEIVAPEADVPPHFAGMLAGVVGMVVGSLAPQTLVRQSHGHSAHLNIG
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEC
AHPQSRN
CCCCCCC
>Mature Secondary Structure
MLIGFVTAYLVLSIAIGLYAATRVKNSTDYVAAGRNLPLYIVTATVFATWFGSETVLGIS
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEHHHHHHHHHCCCCEEEEEH
ATFIDEGLRGLWSDPFGASLCLILAGLFFARPLYRMNLLTLGDYYRTRYGRTVEVLCSLA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
IVVSYLGWVSAQISALGLVFNILSEGSISAETGMLVGAGIVLAYTLFGGMWSVALTDFMQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAIIIVGLAYIAWLVGDMAGGVGAVVAHANEAGKLNFLPAFDAKDIIAFTAGILTMGFGS
HHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCCCEEEECCCCCHHHHHHHHHHHHHCCCC
IPQQDVFQRFNAARNERIAVQGTLLGGSGYFLFAFIPLFIAYSATLIDPALVANYQESDS
CCHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCH
QQILPQLILEHTPLFAQVLFFGALLSAIMSTASGTLLAPSVTFSENILRSTFRGMNDRQF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCCCCCHH
LVMTRVVVVLFALLVTWYAIHTDESIHGMVENAYKVTLATAFVPLAFGLYWKRASTQGAL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VSIVAGLAVWVLLEIVAPEADVPPHFAGMLAGVVGMVVGSLAPQTLVRQSHGHSAHLNIG
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEC
AHPQSRN
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]