Click here to switch to the map view.

The map label for this gene is ribE [H]

Identifier: 119896611

GI number: 119896611

Start: 344623

End: 345237

Strand: Reverse

Name: ribE [H]

Synonym: azo0320

Alternate gene names: 119896611

Gene position: 345237-344623 (Counterclockwise)

Preceding gene: 119896612

Following gene: 119896610

Centisome position: 7.89

GC content: 65.69

Gene sequence:

>615_bases
ATGTTCTCCGGCATTGTGGCCGCTTGCGGCCGTATTGAACGCATCGAACCGCTGGCCGACGGCCTGCGGCTCACGGTAGA
CACCGCCGGCCTCGACCTCGCCGACGTGCAGATCGGCGACAGCATCGCCAACAGCGGCGTCTGCCTCACCGTGATCGAGC
GCGACGGCCCGCGCGTCCGCTTCGACGTCTCACGCGAGACGCTCAACTGCACCGTCGGCCTCGACGTCGAGGGCGGCGAA
GTCAATCTGGAGAAGGCGCTGCAGCTGTCGGACCGCCTCGGCGGCCACCTCGTCACCGGCCATGTGGACGGCGTGGGCGA
AGTGCTGAAATTCGCCCCGATCGGCGAAAGCCATGAGCTGGTGATCCGCGCCCCGGGCGCCATCGCCGGTTACATCGCCA
AGAAGGGCTCGGTCACCGTCAACGGCGTCAGCCTTACGGTCAATCGCGTCGAAGGGCCGGACTTCTCGATCAACCTGATC
CCGCACACCGTGGCGGTGACCAACCTCAAGCATCTCAAGGCGGGCAGCCGGGTCAATCTCGAGATCGACCTGATCGCCCG
CTACGTCGAACGCATGCTCGCCTGGCGCGAAGAAGAATCCAAGGACAAGCCATGA

Upstream 100 bases:

>100_bases
GAAGCCTTCGCCGGCGTGCTCGACAGCGCCCTGCGCCGATAGGAAACCCACCGCGGTTTTCGCCTACAATCCCGCTTTCC
CCTTTTCCGTCAGTCCCTTC

Downstream 100 bases:

>100_bases
GCGCACTTTCCCCCATCAGCGAGATCATCGCCGACATCCGTGCCGGCAAGATGGTCATCCTCGTCGACGAGGAAGACCGC
GAAAACGAGGGCGATGTGGT

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MFSGIVAACGRIERIEPLADGLRLTVDTAGLDLADVQIGDSIANSGVCLTVIERDGPRVRFDVSRETLNCTVGLDVEGGE
VNLEKALQLSDRLGGHLVTGHVDGVGEVLKFAPIGESHELVIRAPGAIAGYIAKKGSVTVNGVSLTVNRVEGPDFSINLI
PHTVAVTNLKHLKAGSRVNLEIDLIARYVERMLAWREEESKDKP

Sequences:

>Translated_204_residues
MFSGIVAACGRIERIEPLADGLRLTVDTAGLDLADVQIGDSIANSGVCLTVIERDGPRVRFDVSRETLNCTVGLDVEGGE
VNLEKALQLSDRLGGHLVTGHVDGVGEVLKFAPIGESHELVIRAPGAIAGYIAKKGSVTVNGVSLTVNRVEGPDFSINLI
PHTVAVTNLKHLKAGSRVNLEIDLIARYVERMLAWREEESKDKP
>Mature_204_residues
MFSGIVAACGRIERIEPLADGLRLTVDTAGLDLADVQIGDSIANSGVCLTVIERDGPRVRFDVSRETLNCTVGLDVEGGE
VNLEKALQLSDRLGGHLVTGHVDGVGEVLKFAPIGESHELVIRAPGAIAGYIAKKGSVTVNGVSLTVNRVEGPDFSINLI
PHTVAVTNLKHLKAGSRVNLEIDLIARYVERMLAWREEESKDKP

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=203, Percent_Identity=36.4532019704434, Blast_Score=115, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6319733, Length=216, Percent_Identity=34.7222222222222, Blast_Score=111, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 21814; Mature: 21814

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSGIVAACGRIERIEPLADGLRLTVDTAGLDLADVQIGDSIANSGVCLTVIERDGPRVR
CCCCHHHHHCCCHHHHHHHCCEEEEEECCCCEEEEEEECCCCCCCCEEEEEEECCCCEEE
FDVSRETLNCTVGLDVEGGEVNLEKALQLSDRLGGHLVTGHVDGVGEVLKFAPIGESHEL
EEECCCEEEEEEEEEECCCEECHHHHHHHHHHCCCEEEEECCCCHHHHHEECCCCCCCEE
VIRAPGAIAGYIAKKGSVTVNGVSLTVNRVEGPDFSINLIPHTVAVTNLKHLKAGSRVNL
EEECCCCEEEEEECCCCEEEEEEEEEEEEECCCCEEEEECCCEEEECCHHHHCCCCEEEE
EIDLIARYVERMLAWREEESKDKP
EHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MFSGIVAACGRIERIEPLADGLRLTVDTAGLDLADVQIGDSIANSGVCLTVIERDGPRVR
CCCCHHHHHCCCHHHHHHHCCEEEEEECCCCEEEEEEECCCCCCCCEEEEEEECCCCEEE
FDVSRETLNCTVGLDVEGGEVNLEKALQLSDRLGGHLVTGHVDGVGEVLKFAPIGESHEL
EEECCCEEEEEEEEEECCCEECHHHHHHHHHHCCCEEEEECCCCHHHHHEECCCCCCCEE
VIRAPGAIAGYIAKKGSVTVNGVSLTVNRVEGPDFSINLIPHTVAVTNLKHLKAGSRVNL
EEECCCCEEEEEECCCCEEEEEEEEEEEEECCCCEEEEECCCEEEECCHHHHCCCCEEEE
EIDLIARYVERMLAWREEESKDKP
EHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]