Click here to switch to the map view.

The map label for this gene is cutA2 [H]

Identifier: 119896612

GI number: 119896612

Start: 345296

End: 347116

Strand: Reverse

Name: cutA2 [H]

Synonym: azo0321

Alternate gene names: 119896612

Gene position: 347116-345296 (Counterclockwise)

Preceding gene: 119896613

Following gene: 119896611

Centisome position: 7.93

GC content: 71.11

Gene sequence:

>1821_bases
GTGATCCACCGCCTGTTCGCCCTGCTCGCCATCCTCGCCTGCCTCCTCGCCCACCCCGCACGCGCCAGCGAGCCGATCGA
GCCGGAAAAAGCTTTTGCGATGCAGGCGCGCGCGCTCGACGCGCAAACGGTGGAGGTGGTGTTCGAGATCGCCAAGGACT
ACTACCTGTACGGCAGCAAGTTCCGCTTCTCTGCCCAGCCCGCAGGGGTGACGCTGGGCGAGGTCCAGCGTCCGCCGGGC
AAGCTCAAACACGACGAGTTCTTCGGCGAGGTGGAAACCTACCGCGGCACCCTACGCATGCTGGTGCCGGTCGCCGCCCC
CGCCGGGGTCGATGCGATCGAGCTGACGGTCAGTAGTCAGGGCTGCTGGGACGGCGGCGTTTGCTACCCGCCGCTGCCGC
AGCAGGCGCGCGTGGCGCTGGTCGCGGCCTCACCGGCCGCCGGCGCCAGCCTGCTCGACGGTGCGCTCGCGCGCGGCGAC
GTGCTGGCCTCCGACGCCGTGGCGCCGCCGGCCGCGGTCTCGCTCGATGAAAGCGGCCGCATCGCCGGTCTGCTGCGCGA
CGCCAGCGTGCCGCTGGTGCTGGCGAGCTTCTTCGGCTTCGGCCTGCTGCTCGCATTCACGCCCTGCCATTTCCCGATGA
TCCCGATCCTGTCCGGCATCATCGTCGGCGGTGGCGGCCAGCATCTGTCGCGCACCCGCACCTTTGCGCTATCGCTCGCC
TACGTGCTGGGGATGGCGGTCACCTATGCGCTGGCCGGGGTCGGCGCCGGGCTCTCGGGCACGCTGCTGGTGGCGGCGCT
GCAGAACGTGTGGGTGCTGTCCGCCTTCGCGCTGGTGTTCGTGGCGCTGGCGCTGTCGATGTTCGGCTTCTACGAACTGC
AACTGCCGAGCGCGCTGCAAAGCCGCATTGCCGACACCGCCAGCCACAACAAGGGTGGCCATCTGGGCGGCGTCGCCGCG
ATGGGCGCGCTGTCGGCGCTGATCGTCGGCCCCTGCCTCGCCGCGCCGCTGGCGGGGGCGCTGCTCTACATCGCCCGCAG
CGGCGATGCCGCGCTAGGCGGCGGCGCGCTGTTCGCGATGGGCCTGGGGCTGGGCGCCCCGCTGCTGGCGGTGGGCATGG
CCACGCGCTCGGTGCTGCCCAAGGTCGGACCGTGGATGGACGGGGTCAAGAAGGCGTTCGGCGTGATCCTGCTCGGCGTT
GCGATCTGGCTGCTGATGCCGGTGCTGCCGCCGCTTGCCGGCATGCTGGCGTGGGCGGCGCTGCTGCTGTTCTCCGGCAT
CTTCCTGCACGCGCTCGACCCGCTTCCGCCGCATGCGCATGGCTGGCAGCGCTTCTGGAAGGGCGTGGGCGTGGTGCTGG
CCATCGGTGGCGCGGCGATGCTGGTGGGCGCGCTCGCAGGTTCGCGCGATCCGCTGCAGCCGCTCGCGGTGCTGCGCGCC
GAGGCCTCGCCGGCCGCCGAGACGGTGCGCTTCGAGCGCGTCGGCTCGCTGGCCGAGCTGGAAAGCCGCCTCGCCGCCGC
CGAGCGCCCGGTGATGCTCGACTTCTATGCCGACTGGTGCGTGTCGTGCAAGGAAATGGAGCGCTACACCTTTCCCGATC
CGCAGGTGGCGCAGCGGCTGGCACAGATGACGCTTCTGAAGGCCGACGTGACTGCCAACAGCGAGGAGCACAAGGCGCTG
CTCAAGCGCTTCGGCCTGTTCGGCCCGCCCGGCATCATCTTCTTCGACGGCGCCGGCCGCGAACGCACCGACCTGCGCGT
GGTGGGCTTCCAGAAGCCCGAAGCCTTCGCCGGCGTGCTCGACAGCGCCCTGCGCCGATAG

Upstream 100 bases:

>100_bases
CTGCCGGGCTATCTCGACTGGGTGAGCACGGAGACCGCGCCGGGCTGATGCCGGCCCGCCGCCCGCCTCCCTTCACGCCC
CCAACCCGGACCGTCCCTCC

Downstream 100 bases:

>100_bases
GAAACCCACCGCGGTTTTCGCCTACAATCCCGCTTTCCCCTTTTCCGTCAGTCCCTTCATGTTCTCCGGCATTGTGGCCG
CTTGCGGCCGTATTGAACGC

Product: putative protein disulfide-isomerase

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 606; Mature: 606

Protein sequence:

>606_residues
MIHRLFALLAILACLLAHPARASEPIEPEKAFAMQARALDAQTVEVVFEIAKDYYLYGSKFRFSAQPAGVTLGEVQRPPG
KLKHDEFFGEVETYRGTLRMLVPVAAPAGVDAIELTVSSQGCWDGGVCYPPLPQQARVALVAASPAAGASLLDGALARGD
VLASDAVAPPAAVSLDESGRIAGLLRDASVPLVLASFFGFGLLLAFTPCHFPMIPILSGIIVGGGGQHLSRTRTFALSLA
YVLGMAVTYALAGVGAGLSGTLLVAALQNVWVLSAFALVFVALALSMFGFYELQLPSALQSRIADTASHNKGGHLGGVAA
MGALSALIVGPCLAAPLAGALLYIARSGDAALGGGALFAMGLGLGAPLLAVGMATRSVLPKVGPWMDGVKKAFGVILLGV
AIWLLMPVLPPLAGMLAWAALLLFSGIFLHALDPLPPHAHGWQRFWKGVGVVLAIGGAAMLVGALAGSRDPLQPLAVLRA
EASPAAETVRFERVGSLAELESRLAAAERPVMLDFYADWCVSCKEMERYTFPDPQVAQRLAQMTLLKADVTANSEEHKAL
LKRFGLFGPPGIIFFDGAGRERTDLRVVGFQKPEAFAGVLDSALRR

Sequences:

>Translated_606_residues
MIHRLFALLAILACLLAHPARASEPIEPEKAFAMQARALDAQTVEVVFEIAKDYYLYGSKFRFSAQPAGVTLGEVQRPPG
KLKHDEFFGEVETYRGTLRMLVPVAAPAGVDAIELTVSSQGCWDGGVCYPPLPQQARVALVAASPAAGASLLDGALARGD
VLASDAVAPPAAVSLDESGRIAGLLRDASVPLVLASFFGFGLLLAFTPCHFPMIPILSGIIVGGGGQHLSRTRTFALSLA
YVLGMAVTYALAGVGAGLSGTLLVAALQNVWVLSAFALVFVALALSMFGFYELQLPSALQSRIADTASHNKGGHLGGVAA
MGALSALIVGPCLAAPLAGALLYIARSGDAALGGGALFAMGLGLGAPLLAVGMATRSVLPKVGPWMDGVKKAFGVILLGV
AIWLLMPVLPPLAGMLAWAALLLFSGIFLHALDPLPPHAHGWQRFWKGVGVVLAIGGAAMLVGALAGSRDPLQPLAVLRA
EASPAAETVRFERVGSLAELESRLAAAERPVMLDFYADWCVSCKEMERYTFPDPQVAQRLAQMTLLKADVTANSEEHKAL
LKRFGLFGPPGIIFFDGAGRERTDLRVVGFQKPEAFAGVLDSALRR
>Mature_606_residues
MIHRLFALLAILACLLAHPARASEPIEPEKAFAMQARALDAQTVEVVFEIAKDYYLYGSKFRFSAQPAGVTLGEVQRPPG
KLKHDEFFGEVETYRGTLRMLVPVAAPAGVDAIELTVSSQGCWDGGVCYPPLPQQARVALVAASPAAGASLLDGALARGD
VLASDAVAPPAAVSLDESGRIAGLLRDASVPLVLASFFGFGLLLAFTPCHFPMIPILSGIIVGGGGQHLSRTRTFALSLA
YVLGMAVTYALAGVGAGLSGTLLVAALQNVWVLSAFALVFVALALSMFGFYELQLPSALQSRIADTASHNKGGHLGGVAA
MGALSALIVGPCLAAPLAGALLYIARSGDAALGGGALFAMGLGLGAPLLAVGMATRSVLPKVGPWMDGVKKAFGVILLGV
AIWLLMPVLPPLAGMLAWAALLLFSGIFLHALDPLPPHAHGWQRFWKGVGVVLAIGGAAMLVGALAGSRDPLQPLAVLRA
EASPAAETVRFERVGSLAELESRLAAAERPVMLDFYADWCVSCKEMERYTFPDPQVAQRLAQMTLLKADVTANSEEHKAL
LKRFGLFGPPGIIFFDGAGRERTDLRVVGFQKPEAFAGVLDSALRR

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=609, Percent_Identity=37.4384236453202, Blast_Score=367, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 63383; Mature: 63383

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHRLFALLAILACLLAHPARASEPIEPEKAFAMQARALDAQTVEVVFEIAKDYYLYGSK
CHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHEECCE
FRFSAQPAGVTLGEVQRPPGKLKHDEFFGEVETYRGTLRMLVPVAAPAGVDAIELTVSSQ
EEECCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
GCWDGGVCYPPLPQQARVALVAASPAAGASLLDGALARGDVLASDAVAPPAAVSLDESGR
CCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHCCCCCCCCCEEECCCCCC
IAGLLRDASVPLVLASFFGFGLLLAFTPCHFPMIPILSGIIVGGGGQHLSRTRTFALSLA
EEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCEEECCCCHHHHHHHHHHHHHH
YVLGMAVTYALAGVGAGLSGTLLVAALQNVWVLSAFALVFVALALSMFGFYELQLPSALQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHH
SRIADTASHNKGGHLGGVAAMGALSALIVGPCLAAPLAGALLYIARSGDAALGGGALFAM
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHH
GLGLGAPLLAVGMATRSVLPKVGPWMDGVKKAFGVILLGVAIWLLMPVLPPLAGMLAWAA
HHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLFSGIFLHALDPLPPHAHGWQRFWKGVGVVLAIGGAAMLVGALAGSRDPLQPLAVLRA
HHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHC
EASPAAETVRFERVGSLAELESRLAAAERPVMLDFYADWCVSCKEMERYTFPDPQVAQRL
CCCCHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCCCHHHHHHH
AQMTLLKADVTANSEEHKALLKRFGLFGPPGIIFFDGAGRERTDLRVVGFQKPEAFAGVL
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEEECCCCHHHHHHH
DSALRR
HHHHCC
>Mature Secondary Structure
MIHRLFALLAILACLLAHPARASEPIEPEKAFAMQARALDAQTVEVVFEIAKDYYLYGSK
CHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHEECCE
FRFSAQPAGVTLGEVQRPPGKLKHDEFFGEVETYRGTLRMLVPVAAPAGVDAIELTVSSQ
EEECCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
GCWDGGVCYPPLPQQARVALVAASPAAGASLLDGALARGDVLASDAVAPPAAVSLDESGR
CCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHCCCCCCCCCEEECCCCCC
IAGLLRDASVPLVLASFFGFGLLLAFTPCHFPMIPILSGIIVGGGGQHLSRTRTFALSLA
EEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCEEECCCCHHHHHHHHHHHHHH
YVLGMAVTYALAGVGAGLSGTLLVAALQNVWVLSAFALVFVALALSMFGFYELQLPSALQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHH
SRIADTASHNKGGHLGGVAAMGALSALIVGPCLAAPLAGALLYIARSGDAALGGGALFAM
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHH
GLGLGAPLLAVGMATRSVLPKVGPWMDGVKKAFGVILLGVAIWLLMPVLPPLAGMLAWAA
HHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLFSGIFLHALDPLPPHAHGWQRFWKGVGVVLAIGGAAMLVGALAGSRDPLQPLAVLRA
HHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHC
EASPAAETVRFERVGSLAELESRLAAAERPVMLDFYADWCVSCKEMERYTFPDPQVAQRL
CCCCHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCCCHHHHHHH
AQMTLLKADVTANSEEHKALLKRFGLFGPPGIIFFDGAGRERTDLRVVGFQKPEAFAGVL
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEEECCCCHHHHHHH
DSALRR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]