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The map label for this gene is ribAB [H]

Identifier: 119896610

GI number: 119896610

Start: 343535

End: 344626

Strand: Reverse

Name: ribAB [H]

Synonym: azo0319

Alternate gene names: 119896610

Gene position: 344626-343535 (Counterclockwise)

Preceding gene: 119896611

Following gene: 119896609

Centisome position: 7.88

GC content: 68.32

Gene sequence:

>1092_bases
ATGAGCGCACTTTCCCCCATCAGCGAGATCATCGCCGACATCCGTGCCGGCAAGATGGTCATCCTCGTCGACGAGGAAGA
CCGCGAAAACGAGGGCGATGTGGTCCTCGCCGCCGAATTCGTCACCCCGGAAGCGATCAACTTCATGGTCACGCACTGCC
GTGGCCTCGTGTGCCTGACGCTGACCGACGAACGCTGCCGCCAGCTCGGCCTGGAGCAGATGGTGCGCAACAACCGCACC
CCGCACGGCACCGCCTTCACCGCGTCGATCGAAGCCGCCACCGGCGTCACCACCGGCATCTCGGCGCACGACCGCTCGCG
CACCGTGCAGGTGGCGGTCGCCCGCCACGCCAAGCCGGACGACATCGTGATGCCCGGCCACATCTTCCCGCTTACCGCAC
AGAAGGGCGGCGTGCTGATCCGCGCCGGCCACACCGAAGCCGGCTGCGACCTCGCCCAGCTCGCCGGACTGGAACCCGCC
GCGGTGATCTGCGAGATCCTCAAGGACGACGGCACCATGGCGCGGCTGCCCGACCTGATCGAGTTCGCTGCCCAGCACGG
CCTCAAGATCGGCGCGATCCGCGACCTGATCGAGTACCGCGCGGCCACCGAACACCTGGTCGAGAAGGTCACCGAAAAGG
ATGTGGACACGCCGCACGGCCGCTTCCGTCTGTCCGCCTTCGAAGACCGTACCTCGGGCGACATCCACTTCGCGCTGACG
CGCGGCGAAATCAGCCCGGACCGCGAAACCCTGGTGCGGGTGCACGAGCCGATCTCGGTGGTCGACTTCCTCGACCCCGC
CAGCGGCAAGCACAGCTTCCCGGTGAACGACGCGCTGGCCGCGATCGCGAAGGCCGAAGCCGGCGCCATCGTGCTGTTGT
ACCGCCCGCAGTCCGGCACCGACCTGCTCGCCAGCCTCACCGGCACCACGGTCGAACGTCCGGTGAAATGGGACCCGCGC
CTGTTCGGCGTCGGCGCCCAGATCCTCCGGGCGCTCGGCGTGGGGCGCATGCGCCTGCTCGCCAATCCGCGCAAGATCCC
CAGCATGGCCGGCTTCGGCCTCGAAATCACCGGCTTCGTCGAAAAGCCCTGA

Upstream 100 bases:

>100_bases
ATCTCAAGGCGGGCAGCCGGGTCAATCTCGAGATCGACCTGATCGCCCGCTACGTCGAACGCATGCTCGCCTGGCGCGAA
GAAGAATCCAAGGACAAGCC

Downstream 100 bases:

>100_bases
CAACAACGGCGCCCTGCGCGGCGCCTCTCCACCCACAGAACACTTCACACCATGGCCCGTTACGACAACATCGCTGAATT
CGAATCCGACCTCAACGGCA

Product: bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSALSPISEIIADIRAGKMVILVDEEDRENEGDVVLAAEFVTPEAINFMVTHCRGLVCLTLTDERCRQLGLEQMVRNNRT
PHGTAFTASIEAATGVTTGISAHDRSRTVQVAVARHAKPDDIVMPGHIFPLTAQKGGVLIRAGHTEAGCDLAQLAGLEPA
AVICEILKDDGTMARLPDLIEFAAQHGLKIGAIRDLIEYRAATEHLVEKVTEKDVDTPHGRFRLSAFEDRTSGDIHFALT
RGEISPDRETLVRVHEPISVVDFLDPASGKHSFPVNDALAAIAKAEAGAIVLLYRPQSGTDLLASLTGTTVERPVKWDPR
LFGVGAQILRALGVGRMRLLANPRKIPSMAGFGLEITGFVEKP

Sequences:

>Translated_363_residues
MSALSPISEIIADIRAGKMVILVDEEDRENEGDVVLAAEFVTPEAINFMVTHCRGLVCLTLTDERCRQLGLEQMVRNNRT
PHGTAFTASIEAATGVTTGISAHDRSRTVQVAVARHAKPDDIVMPGHIFPLTAQKGGVLIRAGHTEAGCDLAQLAGLEPA
AVICEILKDDGTMARLPDLIEFAAQHGLKIGAIRDLIEYRAATEHLVEKVTEKDVDTPHGRFRLSAFEDRTSGDIHFALT
RGEISPDRETLVRVHEPISVVDFLDPASGKHSFPVNDALAAIAKAEAGAIVLLYRPQSGTDLLASLTGTTVERPVKWDPR
LFGVGAQILRALGVGRMRLLANPRKIPSMAGFGLEITGFVEKP
>Mature_362_residues
SALSPISEIIADIRAGKMVILVDEEDRENEGDVVLAAEFVTPEAINFMVTHCRGLVCLTLTDERCRQLGLEQMVRNNRTP
HGTAFTASIEAATGVTTGISAHDRSRTVQVAVARHAKPDDIVMPGHIFPLTAQKGGVLIRAGHTEAGCDLAQLAGLEPAA
VICEILKDDGTMARLPDLIEFAAQHGLKIGAIRDLIEYRAATEHLVEKVTEKDVDTPHGRFRLSAFEDRTSGDIHFALTR
GEISPDRETLVRVHEPISVVDFLDPASGKHSFPVNDALAAIAKAEAGAIVLLYRPQSGTDLLASLTGTTVERPVKWDPRL
FGVGAQILRALGVGRMRLLANPRKIPSMAGFGLEITGFVEKP

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=198, Percent_Identity=52.5252525252525, Blast_Score=215, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6320695, Length=204, Percent_Identity=43.6274509803922, Blast_Score=166, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 39164; Mature: 39033

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALSPISEIIADIRAGKMVILVDEEDRENEGDVVLAAEFVTPEAINFMVTHCRGLVCLT
CCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEE
LTDERCRQLGLEQMVRNNRTPHGTAFTASIEAATGVTTGISAHDRSRTVQVAVARHAKPD
ECHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCC
DIVMPGHIFPLTAQKGGVLIRAGHTEAGCDLAQLAGLEPAAVICEILKDDGTMARLPDLI
CEEECCEEEEEECCCCCEEEEECCCCCCCCHHHHCCCCHHHHHHHHHHCCCCHHHHHHHH
EFAAQHGLKIGAIRDLIEYRAATEHLVEKVTEKDVDTPHGRFRLSAFEDRTSGDIHFALT
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEE
RGEISPDRETLVRVHEPISVVDFLDPASGKHSFPVNDALAAIAKAEAGAIVLLYRPQSGT
CCCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCC
DLLASLTGTTVERPVKWDPRLFGVGAQILRALGVGRMRLLANPRKIPSMAGFGLEITGFV
HHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCEEEEEEE
EKP
CCC
>Mature Secondary Structure 
SALSPISEIIADIRAGKMVILVDEEDRENEGDVVLAAEFVTPEAINFMVTHCRGLVCLT
CCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEE
LTDERCRQLGLEQMVRNNRTPHGTAFTASIEAATGVTTGISAHDRSRTVQVAVARHAKPD
ECHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCC
DIVMPGHIFPLTAQKGGVLIRAGHTEAGCDLAQLAGLEPAAVICEILKDDGTMARLPDLI
CEEECCEEEEEECCCCCEEEEECCCCCCCCHHHHCCCCHHHHHHHHHHCCCCHHHHHHHH
EFAAQHGLKIGAIRDLIEYRAATEHLVEKVTEKDVDTPHGRFRLSAFEDRTSGDIHFALT
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEE
RGEISPDRETLVRVHEPISVVDFLDPASGKHSFPVNDALAAIAKAEAGAIVLLYRPQSGT
CCCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCC
DLLASLTGTTVERPVKWDPRLFGVGAQILRALGVGRMRLLANPRKIPSMAGFGLEITGFV
HHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCEEEEEEE
EKP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]