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The map label for this gene is dctM1 [H]

Identifier: 119896533

GI number: 119896533

Start: 268055

End: 269338

Strand: Direct

Name: dctM1 [H]

Synonym: azo0242

Alternate gene names: 119896533

Gene position: 268055-269338 (Clockwise)

Preceding gene: 119896532

Following gene: 119896535

Centisome position: 6.13

GC content: 69.0

Gene sequence:

>1284_bases
ATGACCGGCGTCGTACTGATCGGCCTGTTCCTGCTTGCGCTGGTGGCCGGGCTGCCGCTCGCCGTGGGCCTCGGGGTCGC
CAGCATCGCGGTGCTCGCGCTGGCCGGCTTCGACCAGCTCGCGGTGCCCACCAACATCTACGCCGGCATCGCCAAGTACC
CCTTGCTCGCGATCCCGATGTTCATCCTCGCCGGCATGATCTTCGAGCGGTCCGGCGTCGCGCTGCGACTGGTGCGCTTC
GTCACCGCGATGGTGGGCGAATGGACCGGCTCGCTGGCGGTGGTGGCGGTGCTGGTGTCGATGCTGCTGGGCGGCATCTC
CGGCTCCGGCCCCGCCGATGCGGCGGCGGTGGCGGCGGTGATGCTGCCGTCGATGGTGGCGCGCGGCTATCCCAAGGGCT
TTTCGGCGGGGTTGATCGCGGCCGCCGGTTCGACCGCGATCGTGATCCCGCCTTCGGTCGCCTTCATCGTCTACAGCGTG
ATGGTGCCGGCGGCGACGGTGCCGGCGCTGTTCGCCGCGGGGCTCTTCCCGGGCATGATCGCCGCGCTGTGCCTGCTGAT
TCCGGCGGTGCTCATCAGCCGCAAGTACGGTTTCGGGCGCGATTACCGCGCCGAGCGGCCGCCGCTGGGCAAGAGCTTCG
TCGATGCGATCTGGGGCCTGCTGGCGCCGGTCATCATCCTCGGCGGCCTGCGCGCCGGCATCTTCACCCCCACCGAGGCC
GCGGTGGTGGCGGTGGCCTACGGCATCTTCGTCGGCATGGTGGTGTACCGCACGATCACGCCGAAAACGCTGTTCCGCCT
GCTGGTGGATGCCGGCGAGCTGTCGGCGGTGGTGATGATGATCATCGGCGTGGCGTCGGTGTTCGCGTGGGCGGGCAACA
CGCTCGGCATCTTCGATGCGGCGGCCAAGGCGCTGGTGGAGATGCACCCGGGACACTGGGGGATGCTGCTGTCGGTCAAC
CTGCTGCTGCTGGTGGCGGGGATGTTCCTCGACGCGGTGTCGATCTTCCTGATCCTGCTGCCGCTGCTGGTGCCGATCGC
GCTCGCGATGGGCTGGGACCTGGTGTGGTTCGGCGTGATGATGACGATCAACCTCGCCATCGGCCAGTTCACGCCGCCGA
TGGCGCTGTCGCTGATGATCACCTCGCGCATCGCCGGCATCGGCATCGAGCAGACCTTCCGCTGGGTGATCTGGTTCGTG
CTGGCGATGGGCGCCGGGCTGGCGGCGATGGTGGTGTTTCCGGAACTGGCGCTGTGGTTGCCGCGCCGGCTGGGCTACGT
GTAG

Upstream 100 bases:

>100_bases
CGGCGCTCGGGCTGCCGCAGTGGTGGTACACCGTGTGGATGCCGGCGCTGGCGGTGGTGATCGTGCTGCGCCTCGTGGTC
ACCCGGCTGGGAGCGCGCTC

Downstream 100 bases:

>100_bases
GCGCGGCGGATCGACGCGGACGGGGCGCTCAGTGCGGCGCCTCGCCCGGTGCAGGTGCAGCCAGCGCGTCGGTGATGATG
AAGCGGATCACGCGCTGGAA

Product: TRAP-type C4-dicarboxylate transport system large permease

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MTGVVLIGLFLLALVAGLPLAVGLGVASIAVLALAGFDQLAVPTNIYAGIAKYPLLAIPMFILAGMIFERSGVALRLVRF
VTAMVGEWTGSLAVVAVLVSMLLGGISGSGPADAAAVAAVMLPSMVARGYPKGFSAGLIAAAGSTAIVIPPSVAFIVYSV
MVPAATVPALFAAGLFPGMIAALCLLIPAVLISRKYGFGRDYRAERPPLGKSFVDAIWGLLAPVIILGGLRAGIFTPTEA
AVVAVAYGIFVGMVVYRTITPKTLFRLLVDAGELSAVVMMIIGVASVFAWAGNTLGIFDAAAKALVEMHPGHWGMLLSVN
LLLLVAGMFLDAVSIFLILLPLLVPIALAMGWDLVWFGVMMTINLAIGQFTPPMALSLMITSRIAGIGIEQTFRWVIWFV
LAMGAGLAAMVVFPELALWLPRRLGYV

Sequences:

>Translated_427_residues
MTGVVLIGLFLLALVAGLPLAVGLGVASIAVLALAGFDQLAVPTNIYAGIAKYPLLAIPMFILAGMIFERSGVALRLVRF
VTAMVGEWTGSLAVVAVLVSMLLGGISGSGPADAAAVAAVMLPSMVARGYPKGFSAGLIAAAGSTAIVIPPSVAFIVYSV
MVPAATVPALFAAGLFPGMIAALCLLIPAVLISRKYGFGRDYRAERPPLGKSFVDAIWGLLAPVIILGGLRAGIFTPTEA
AVVAVAYGIFVGMVVYRTITPKTLFRLLVDAGELSAVVMMIIGVASVFAWAGNTLGIFDAAAKALVEMHPGHWGMLLSVN
LLLLVAGMFLDAVSIFLILLPLLVPIALAMGWDLVWFGVMMTINLAIGQFTPPMALSLMITSRIAGIGIEQTFRWVIWFV
LAMGAGLAAMVVFPELALWLPRRLGYV
>Mature_426_residues
TGVVLIGLFLLALVAGLPLAVGLGVASIAVLALAGFDQLAVPTNIYAGIAKYPLLAIPMFILAGMIFERSGVALRLVRFV
TAMVGEWTGSLAVVAVLVSMLLGGISGSGPADAAAVAAVMLPSMVARGYPKGFSAGLIAAAGSTAIVIPPSVAFIVYSVM
VPAATVPALFAAGLFPGMIAALCLLIPAVLISRKYGFGRDYRAERPPLGKSFVDAIWGLLAPVIILGGLRAGIFTPTEAA
VVAVAYGIFVGMVVYRTITPKTLFRLLVDAGELSAVVMMIIGVASVFAWAGNTLGIFDAAAKALVEMHPGHWGMLLSVNL
LLLVAGMFLDAVSIFLILLPLLVPIALAMGWDLVWFGVMMTINLAIGQFTPPMALSLMITSRIAGIGIEQTFRWVIWFVL
AMGAGLAAMVVFPELALWLPRRLGYV

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=395, Percent_Identity=35.4430379746835, Blast_Score=179, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 44497; Mature: 44366

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCC
>Mature Secondary Structure 
TGVVLIGLFLLALVAGLPLAVGLGVASIAVLALAGFDQLAVPTNIYAGIAKYPLLAIPM
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHH
FILAGMIFERSGVALRLVRFVTAMVGEWTGSLAVVAVLVSMLLGGISGSGPADAAAVAAV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
MLPSMVARGYPKGFSAGLIAAAGSTAIVIPPSVAFIVYSVMVPAATVPALFAAGLFPGMI
HHHHHHHCCCCCCCCCCHHEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALCLLIPAVLISRKYGFGRDYRAERPPLGKSFVDAIWGLLAPVIILGGLRAGIFTPTEA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AVVAVAYGIFVGMVVYRTITPKTLFRLLVDAGELSAVVMMIIGVASVFAWAGNTLGIFDA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
AAKALVEMHPGHWGMLLSVNLLLLVAGMFLDAVSIFLILLPLLVPIALAMGWDLVWFGVM
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTINLAIGQFTPPMALSLMITSRIAGIGIEQTFRWVIWFVLAMGAGLAAMVVFPELALWL
HHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
PRRLGYV
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]