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The map label for this gene is apbA1 [C]

Identifier: 119896483

GI number: 119896483

Start: 212402

End: 213313

Strand: Direct

Name: apbA1 [C]

Synonym: azo0192

Alternate gene names: 119896483

Gene position: 212402-213313 (Clockwise)

Preceding gene: 119896482

Following gene: 119896485

Centisome position: 4.85

GC content: 69.19

Gene sequence:

>912_bases
ATGGATAGCTCGCGACAGCGGGAGGCCTTCTCCACCGACGTGCTGCAGGCGGCGCCCTACCCGGTTGCCATCATCGGCGC
CGGAGCGCTCGGCCTGTCGCTGGCGTCCCGCCTCATCCGCTCTGGTCCGGTGGCGCTCGTCGCTTCCAATGCGGATGCCG
CGCAGCGGCTTCGCGCCGGCGTGCGGGTGGGCGCCGTCGTCGAGCGTTTCGACGGCTTCGCGGCGCCACGGCTGCCGCGG
GCCGACTGGGTCGTCGTGGTGGTCAAGGCAGGCGGCACCCGCGACGCGCTGCGTTCGGCCTTGGCCATGCGGCCGCGTGG
TGTGCTTTCGCTGCAGAACGGATTGCTCGACCTCGAACCGGCGGGAACGGGCACCTGCGTTGCCCAGGGCGTCACGACCA
TGGGAGCGTTTCGCACCGATGAGGGCGTGATGCCGGTGAGCGACGGGGAAACCTTGATGCCGCAGGGCTTCGAACCGCTT
GCCGCGCTGTTCCAGCAGGCCGGGCTTCCCGCGCGCATCGAAGTGGCCATGCAGGCCGCACGTCTGGCGAAACTGCTGGT
GAACGTGGTTCTCAACCCGCTGACGGCAGTGTTCCGGGTGCGCACGGGCGAGCTACTGGCTGCACCGTATATGAACCATG
TCGAGGCCTTGGTCGCCGAAGCCTGGCCGGTATTGAGGGCAGCGGGCCTGATGCTGGAGTTCGACGAGGCCCGGGCGAAG
GTCTGGAGTGTGGTTCGCAGTACCGCCGACAACCGCACCAGCATGCTGCAGGACGTCCTGGCTGGTCGGCGTACCGAGCG
TGAGGCCATCACCGGCGCCTTCCTGCGTCTTGCCGACGGGAATGGGGCCGCCGTTCCTACCCACCGCGCGCTTCACACCC
TCCTCGGGCAGATCGACGCCGACCGCTGCTGA

Upstream 100 bases:

>100_bases
GACAGGGGCATCGTCACGCTCCGTAGCGAAACCCGCAACCAGCGCGGCGAAATCCTGCAGGTGCTGACCTCCCGCCTGGT
CGTACCACGTCGTCCGCTGA

Downstream 100 bases:

>100_bases
ATCCCTCACCTGCCGAGTTGCCCGCGCACCCAGCGCACCAGCTGCTCGGTGTTCATCGCGCCCGCCTGCCGCGTCACTTC
GCGGCCGCCCTGGAACAGCG

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MDSSRQREAFSTDVLQAAPYPVAIIGAGALGLSLASRLIRSGPVALVASNADAAQRLRAGVRVGAVVERFDGFAAPRLPR
ADWVVVVVKAGGTRDALRSALAMRPRGVLSLQNGLLDLEPAGTGTCVAQGVTTMGAFRTDEGVMPVSDGETLMPQGFEPL
AALFQQAGLPARIEVAMQAARLAKLLVNVVLNPLTAVFRVRTGELLAAPYMNHVEALVAEAWPVLRAAGLMLEFDEARAK
VWSVVRSTADNRTSMLQDVLAGRRTEREAITGAFLRLADGNGAAVPTHRALHTLLGQIDADRC

Sequences:

>Translated_303_residues
MDSSRQREAFSTDVLQAAPYPVAIIGAGALGLSLASRLIRSGPVALVASNADAAQRLRAGVRVGAVVERFDGFAAPRLPR
ADWVVVVVKAGGTRDALRSALAMRPRGVLSLQNGLLDLEPAGTGTCVAQGVTTMGAFRTDEGVMPVSDGETLMPQGFEPL
AALFQQAGLPARIEVAMQAARLAKLLVNVVLNPLTAVFRVRTGELLAAPYMNHVEALVAEAWPVLRAAGLMLEFDEARAK
VWSVVRSTADNRTSMLQDVLAGRRTEREAITGAFLRLADGNGAAVPTHRALHTLLGQIDADRC
>Mature_303_residues
MDSSRQREAFSTDVLQAAPYPVAIIGAGALGLSLASRLIRSGPVALVASNADAAQRLRAGVRVGAVVERFDGFAAPRLPR
ADWVVVVVKAGGTRDALRSALAMRPRGVLSLQNGLLDLEPAGTGTCVAQGVTTMGAFRTDEGVMPVSDGETLMPQGFEPL
AALFQQAGLPARIEVAMQAARLAKLLVNVVLNPLTAVFRVRTGELLAAPYMNHVEALVAEAWPVLRAAGLMLEFDEARAK
VWSVVRSTADNRTSMLQDVLAGRRTEREAITGAFLRLADGNGAAVPTHRALHTLLGQIDADRC

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=233, Percent_Identity=28.755364806867, Blast_Score=78, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 32035; Mature: 32035

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSSRQREAFSTDVLQAAPYPVAIIGAGALGLSLASRLIRSGPVALVASNADAAQRLRAG
CCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHC
VRVGAVVERFDGFAAPRLPRADWVVVVVKAGGTRDALRSALAMRPRGVLSLQNGLLDLEP
CHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHCCCEEECC
AGTGTCVAQGVTTMGAFRTDEGVMPVSDGETLMPQGFEPLAALFQQAGLPARIEVAMQAA
CCCCHHHHHHHHHHHCEECCCCCEECCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
RLAKLLVNVVLNPLTAVFRVRTGELLAAPYMNHVEALVAEAWPVLRAAGLMLEFDEARAK
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHH
VWSVVRSTADNRTSMLQDVLAGRRTEREAITGAFLRLADGNGAAVPTHRALHTLLGQIDA
HHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHCC
DRC
CCC
>Mature Secondary Structure
MDSSRQREAFSTDVLQAAPYPVAIIGAGALGLSLASRLIRSGPVALVASNADAAQRLRAG
CCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHC
VRVGAVVERFDGFAAPRLPRADWVVVVVKAGGTRDALRSALAMRPRGVLSLQNGLLDLEP
CHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHCCCEEECC
AGTGTCVAQGVTTMGAFRTDEGVMPVSDGETLMPQGFEPLAALFQQAGLPARIEVAMQAA
CCCCHHHHHHHHHHHCEECCCCCEECCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
RLAKLLVNVVLNPLTAVFRVRTGELLAAPYMNHVEALVAEAWPVLRAAGLMLEFDEARAK
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHH
VWSVVRSTADNRTSMLQDVLAGRRTEREAITGAFLRLADGNGAAVPTHRALHTLLGQIDA
HHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHCC
DRC
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]