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The map label for this gene is fdoG [H]

Identifier: 119871334

GI number: 119871334

Start: 5545101

End: 5547686

Strand: Direct

Name: fdoG [H]

Synonym: Mkms_5308

Alternate gene names: 119871334

Gene position: 5545101-5547686 (Clockwise)

Preceding gene: 119871333

Following gene: 119871335

Centisome position: 96.65

GC content: 68.17

Gene sequence:

>2586_bases
ATGGCCGAGGCACATCCGGTCGGATTCCAGTGGGTGGTCGAGGCGAAGGCGCGCGGCACCGACGTGGTGCACATCGACCC
GCGGTTCACCCGCACCAGCGCACTGGCCGACCGGTACGTATCGCTGCGCGCCGGTAGCGATATCGCCCTCCTCGGCGGGG
TGATCAACTACATCCTGAGCAACGAGCTGGACTTCCGGGAGTACGTGACCGCGTACACCAACGCATCGTTCATCGTCGAC
GAACGGTTCAGCGACGCCGAGGATCTCGACGGTCTGTTCTCCGGCTACGACGACGCGACCGCCTCCTACGATCCGTCGAC
GTGGCAGTACCAGACCACCGATCCCGAGGAGGGCGGCGCCGAGGCCAAGGAGCAGAGCTCGGGCGACCGCTCCGGGTCCG
GCGGTCCGCCGGTCGAGGGCGGTGCGGGTGACATCCCCAGGGACCCGACGCTGCAGGACCCGCGCTGCGTCTACCAGATC
CTCAAACGGCACTACGCCCGCTACACCCCGGAGATGGTCGAGCGGGTGTGCGGGGTGCCCGCCGAACAGTTCCTCGAGGT
GGCCCGCAAGTGGGCCGAGAACTCCGGGCGGGAGCGGACCGCCGCATTGGTCTACAGCGTCGGGTGGACCCAGCACACGA
TGGGCGCGCAGTTCATCCGCGCCGGCGCGATCATCCAGCTGCTGCTCGGCAACATCGGCCGCCCCGGCGGCGGGGTGTTC
GCACTGCGCGGCCACGCCAGCATCCAGGGCTCGACCGACGTGCCGACGCTGTTCAACCTGCTGCCCGGCTACCTGGCGAT
GCCCCACGCGGGCCAGGAGACGCTGGCCGACTACCTCGACGACATCAAGAGCCGCAACCAGAAGGGCTTCTGGTTCAACG
CCGATGCGTACATGGTGTCGCTGCTCAAGGAGTACTGGGGCGAGCACGCACGGGCGGACAACGACTTCTGCTTCGACTAC
CTGCCGCGCATCAGCGGCGACCACGGCACCTACCGCACGGTGATGGACATGGTCGACGGGAAGGTGTTCGGTTACTTCCT
GCTCGGCCAGAACCCGGCGGTCGGGTCGGCGCACGGCCGTCTGCAGCGCCTGGGCATGGCCAACCTGGACTGGTTGGTGG
TCCGCGACCTCGTCGAGATCGAGAGCGCCACCTTCTGGAAGTCGGGCCCCGAGGTCGAGACGGGTGAGATCACCCCGCAG
ACGTGCCGGACGGAGGTGTTCCTCTTCCCGGCCGCCTCGCATGTGGAGAAGGCGGGCACGTTCACGCAGACGCAACGGAT
GCTGCAGTGGCGGGAGAAGGCCGTCGAGCCGCCGGGCGACGCCCGCTCGGAACTGTGGTTCTTCTACCACCTGGGCCGCA
TCCTGCGGGAGAAGCTGGCCGGCTCCACCGACGAGCGTAACCGTCCGCTGCTCGAATTGTCCTGGGACTACGTGATGGAC
GGCGACGAACCGTCGGGTGAGGACGTACTGCGGCGGATCAGCGGTGTCGACCTCACGACCGGCCGCGCGGTGGACGACTA
CATGTCGCTCAGGGCCGACGGCACCACCATGTCCGGCTGCTGGATCTACAGCGGCGTGTACGCCGACGAGGTCAACCAGG
CGGCGCGCCGCAAACCGCACGACCAGCAGGGGCCCTACGAGAACGAGTGGGGCTGGACGTGGCCGATGAACCGCCGCGTC
CTGTACAACCGGGCCTCGGCGGATCCGCAGGGCCGGCCGTGGAGTGAGCGCAAGAAGCTGGTGTGGTGGGACACCGAGAA
ACAGGAGTGGACGGGGTACGACGTCCCCGACTTCGAGAAGCACAAGCCGCCGGACTACCGGCCCGCCCCGGGTGCGGTGG
GCGTCGAGGCGCTGCACGGGGACGACCCGTTCATCATGCAGGCCGACGGTAAGGCATGGCTGTTCGCGCCGAACGGTCTC
GCGGACGGTCCGCTACCCACACACTACGAACCGCACGAATCGCCGGTGCGCAACCCGCTGTACGCGCAGCAGGGCAATCC
GGCTCGCAAAGTGTATGGACGAGCGGACAATCCGTCGAACCCGTCGCCGCCGGAACTGCACGGTGAGGTGTTCCCGTACG
TGTTCACCGCCGCGCGGCTGACCGAACACCACACCGCGGGCGGGATGAGCCGGCAGCTGCCCTATCTGGCCGAGCTGCAG
CCCGGGCTGTTCGTGGAGGTCTCCCCGCAGCTGGCGGCCGAACGCGGGCTGACCCACATGGAATGGGCGCACGTGATCAC
CAGCCGGGCGGCGGTGGACGCCCGGGTGTTCGTCACCGACCGGATGCGGCCGCTGCGGATCGACGACCATGTGGTGCACC
AGATCTGGATGCCCTACCACTGGGGTAACGCCGGGCTGATCGACGGTGACGTGGTCAACGACCTGCTCGGCGTGGTCGCC
GACCCGAACGTGTTCATCCAGGAGAGCAAGGTCGCGACGTGTGACATCCAGCCGGGCAGGCGCCCCCGCGGACCGGCGCT
GCTCGAGTACATCGCGATGTACCGCGATCGGGCCCGCATCACCGTCGACACCGGGACCGACCTCGACACGACGAAACGGT
CGACCGAACACACCGAGGAAACGTGA

Upstream 100 bases:

>100_bases
CACGGTTCCCGGTCTGGGGGCCTCCTTCGGTCGCGGCGGGGCGACGGACTACCAGCAGGACCTCGTCAACTCGGACTTCA
TCGTCATCATGGGGTCCAAC

Downstream 100 bases:

>100_bases
TGCGCGAGAACAGCTTCTACGGTCCGCTCGAGGATCCGGCCGGTGACGCGGGATATTCGGAGCACCCGCAGCGGGTCGGG
TTCTTCACCGACACCTCGGT

Product: formate dehydrogenase

Products: NA

Alternate protein names: Aerobic formate dehydrogenase major subunit; FDH-Z subunit alpha; Formate dehydrogenase-O subunit alpha [H]

Number of amino acids: Translated: 861; Mature: 860

Protein sequence:

>861_residues
MAEAHPVGFQWVVEAKARGTDVVHIDPRFTRTSALADRYVSLRAGSDIALLGGVINYILSNELDFREYVTAYTNASFIVD
ERFSDAEDLDGLFSGYDDATASYDPSTWQYQTTDPEEGGAEAKEQSSGDRSGSGGPPVEGGAGDIPRDPTLQDPRCVYQI
LKRHYARYTPEMVERVCGVPAEQFLEVARKWAENSGRERTAALVYSVGWTQHTMGAQFIRAGAIIQLLLGNIGRPGGGVF
ALRGHASIQGSTDVPTLFNLLPGYLAMPHAGQETLADYLDDIKSRNQKGFWFNADAYMVSLLKEYWGEHARADNDFCFDY
LPRISGDHGTYRTVMDMVDGKVFGYFLLGQNPAVGSAHGRLQRLGMANLDWLVVRDLVEIESATFWKSGPEVETGEITPQ
TCRTEVFLFPAASHVEKAGTFTQTQRMLQWREKAVEPPGDARSELWFFYHLGRILREKLAGSTDERNRPLLELSWDYVMD
GDEPSGEDVLRRISGVDLTTGRAVDDYMSLRADGTTMSGCWIYSGVYADEVNQAARRKPHDQQGPYENEWGWTWPMNRRV
LYNRASADPQGRPWSERKKLVWWDTEKQEWTGYDVPDFEKHKPPDYRPAPGAVGVEALHGDDPFIMQADGKAWLFAPNGL
ADGPLPTHYEPHESPVRNPLYAQQGNPARKVYGRADNPSNPSPPELHGEVFPYVFTAARLTEHHTAGGMSRQLPYLAELQ
PGLFVEVSPQLAAERGLTHMEWAHVITSRAAVDARVFVTDRMRPLRIDDHVVHQIWMPYHWGNAGLIDGDVVNDLLGVVA
DPNVFIQESKVATCDIQPGRRPRGPALLEYIAMYRDRARITVDTGTDLDTTKRSTEHTEET

Sequences:

>Translated_861_residues
MAEAHPVGFQWVVEAKARGTDVVHIDPRFTRTSALADRYVSLRAGSDIALLGGVINYILSNELDFREYVTAYTNASFIVD
ERFSDAEDLDGLFSGYDDATASYDPSTWQYQTTDPEEGGAEAKEQSSGDRSGSGGPPVEGGAGDIPRDPTLQDPRCVYQI
LKRHYARYTPEMVERVCGVPAEQFLEVARKWAENSGRERTAALVYSVGWTQHTMGAQFIRAGAIIQLLLGNIGRPGGGVF
ALRGHASIQGSTDVPTLFNLLPGYLAMPHAGQETLADYLDDIKSRNQKGFWFNADAYMVSLLKEYWGEHARADNDFCFDY
LPRISGDHGTYRTVMDMVDGKVFGYFLLGQNPAVGSAHGRLQRLGMANLDWLVVRDLVEIESATFWKSGPEVETGEITPQ
TCRTEVFLFPAASHVEKAGTFTQTQRMLQWREKAVEPPGDARSELWFFYHLGRILREKLAGSTDERNRPLLELSWDYVMD
GDEPSGEDVLRRISGVDLTTGRAVDDYMSLRADGTTMSGCWIYSGVYADEVNQAARRKPHDQQGPYENEWGWTWPMNRRV
LYNRASADPQGRPWSERKKLVWWDTEKQEWTGYDVPDFEKHKPPDYRPAPGAVGVEALHGDDPFIMQADGKAWLFAPNGL
ADGPLPTHYEPHESPVRNPLYAQQGNPARKVYGRADNPSNPSPPELHGEVFPYVFTAARLTEHHTAGGMSRQLPYLAELQ
PGLFVEVSPQLAAERGLTHMEWAHVITSRAAVDARVFVTDRMRPLRIDDHVVHQIWMPYHWGNAGLIDGDVVNDLLGVVA
DPNVFIQESKVATCDIQPGRRPRGPALLEYIAMYRDRARITVDTGTDLDTTKRSTEHTEET
>Mature_860_residues
AEAHPVGFQWVVEAKARGTDVVHIDPRFTRTSALADRYVSLRAGSDIALLGGVINYILSNELDFREYVTAYTNASFIVDE
RFSDAEDLDGLFSGYDDATASYDPSTWQYQTTDPEEGGAEAKEQSSGDRSGSGGPPVEGGAGDIPRDPTLQDPRCVYQIL
KRHYARYTPEMVERVCGVPAEQFLEVARKWAENSGRERTAALVYSVGWTQHTMGAQFIRAGAIIQLLLGNIGRPGGGVFA
LRGHASIQGSTDVPTLFNLLPGYLAMPHAGQETLADYLDDIKSRNQKGFWFNADAYMVSLLKEYWGEHARADNDFCFDYL
PRISGDHGTYRTVMDMVDGKVFGYFLLGQNPAVGSAHGRLQRLGMANLDWLVVRDLVEIESATFWKSGPEVETGEITPQT
CRTEVFLFPAASHVEKAGTFTQTQRMLQWREKAVEPPGDARSELWFFYHLGRILREKLAGSTDERNRPLLELSWDYVMDG
DEPSGEDVLRRISGVDLTTGRAVDDYMSLRADGTTMSGCWIYSGVYADEVNQAARRKPHDQQGPYENEWGWTWPMNRRVL
YNRASADPQGRPWSERKKLVWWDTEKQEWTGYDVPDFEKHKPPDYRPAPGAVGVEALHGDDPFIMQADGKAWLFAPNGLA
DGPLPTHYEPHESPVRNPLYAQQGNPARKVYGRADNPSNPSPPELHGEVFPYVFTAARLTEHHTAGGMSRQLPYLAELQP
GLFVEVSPQLAAERGLTHMEWAHVITSRAAVDARVFVTDRMRPLRIDDHVVHQIWMPYHWGNAGLIDGDVVNDLLGVVAD
PNVFIQESKVATCDIQPGRRPRGPALLEYIAMYRDRARITVDTGTDLDTTKRSTEHTEET

Specific function: Allows to use formate as major electron donor during aerobic respiration. Subunit alpha possibly forms the active site [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868720, Length=846, Percent_Identity=38.4160756501182, Blast_Score=537, Evalue=1e-153,
Organism=Escherichia coli, GI3868719, Length=840, Percent_Identity=38.0952380952381, Blast_Score=526, Evalue=1e-150,
Organism=Escherichia coli, GI3868721, Length=278, Percent_Identity=25.5395683453237, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006443
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 96394; Mature: 96262

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEAHPVGFQWVVEAKARGTDVVHIDPRFTRTSALADRYVSLRAGSDIALLGGVINYILS
CCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHC
NELDFREYVTAYTNASFIVDERFSDAEDLDGLFSGYDDATASYDPSTWQYQTTDPEEGGA
CCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCC
EAKEQSSGDRSGSGGPPVEGGAGDIPRDPTLQDPRCVYQILKRHYARYTPEMVERVCGVP
CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCC
AEQFLEVARKWAENSGRERTAALVYSVGWTQHTMGAQFIRAGAIIQLLLGNIGRPGGGVF
HHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
ALRGHASIQGSTDVPTLFNLLPGYLAMPHAGQETLADYLDDIKSRNQKGFWFNADAYMVS
EEECCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEECCHHHHHH
LLKEYWGEHARADNDFCFDYLPRISGDHGTYRTVMDMVDGKVFGYFLLGQNPAVGSAHGR
HHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCHHHH
LQRLGMANLDWLVVRDLVEIESATFWKSGPEVETGEITPQTCRTEVFLFPAASHVEKAGT
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCEEEEEECCHHHHHHHCC
FTQTQRMLQWREKAVEPPGDARSELWFFYHLGRILREKLAGSTDERNRPLLELSWDYVMD
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEC
GDEPSGEDVLRRISGVDLTTGRAVDDYMSLRADGTTMSGCWIYSGVYADEVNQAARRKPH
CCCCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCEECCEEEECCCCHHHHHHHHHCCCC
DQQGPYENEWGWTWPMNRRVLYNRASADPQGRPWSERKKLVWWDTEKQEWTGYDVPDFEK
CCCCCCCCCCCEECCCCCEEEEECCCCCCCCCCHHHCCCEEEEECCCCCCCCCCCCCCCC
HKPPDYRPAPGAVGVEALHGDDPFIMQADGKAWLFAPNGLADGPLPTHYEPHESPVRNPL
CCCCCCCCCCCCCCEEEEECCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCC
YAQQGNPARKVYGRADNPSNPSPPELHGEVFPYVFTAARLTEHHTAGGMSRQLPYLAELQ
CCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHCCCHHHHCC
PGLFVEVSPQLAAERGLTHMEWAHVITSRAAVDARVFVTDRMRPLRIDDHVVHQIWMPYH
CCEEEEECHHHHHHHCCCHHHHHHHHHHHHHHCEEEEEECCCCCEECCHHHHHHHCCCEE
WGNAGLIDGDVVNDLLGVVADPNVFIQESKVATCDIQPGRRPRGPALLEYIAMYRDRARI
CCCCCCCCHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEE
TVDTGTDLDTTKRSTEHTEET
EEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AEAHPVGFQWVVEAKARGTDVVHIDPRFTRTSALADRYVSLRAGSDIALLGGVINYILS
CCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHC
NELDFREYVTAYTNASFIVDERFSDAEDLDGLFSGYDDATASYDPSTWQYQTTDPEEGGA
CCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCC
EAKEQSSGDRSGSGGPPVEGGAGDIPRDPTLQDPRCVYQILKRHYARYTPEMVERVCGVP
CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCC
AEQFLEVARKWAENSGRERTAALVYSVGWTQHTMGAQFIRAGAIIQLLLGNIGRPGGGVF
HHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
ALRGHASIQGSTDVPTLFNLLPGYLAMPHAGQETLADYLDDIKSRNQKGFWFNADAYMVS
EEECCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEECCHHHHHH
LLKEYWGEHARADNDFCFDYLPRISGDHGTYRTVMDMVDGKVFGYFLLGQNPAVGSAHGR
HHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCHHHH
LQRLGMANLDWLVVRDLVEIESATFWKSGPEVETGEITPQTCRTEVFLFPAASHVEKAGT
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCEEEEEECCHHHHHHHCC
FTQTQRMLQWREKAVEPPGDARSELWFFYHLGRILREKLAGSTDERNRPLLELSWDYVMD
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEC
GDEPSGEDVLRRISGVDLTTGRAVDDYMSLRADGTTMSGCWIYSGVYADEVNQAARRKPH
CCCCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCEECCEEEECCCCHHHHHHHHHCCCC
DQQGPYENEWGWTWPMNRRVLYNRASADPQGRPWSERKKLVWWDTEKQEWTGYDVPDFEK
CCCCCCCCCCCEECCCCCEEEEECCCCCCCCCCHHHCCCEEEEECCCCCCCCCCCCCCCC
HKPPDYRPAPGAVGVEALHGDDPFIMQADGKAWLFAPNGLADGPLPTHYEPHESPVRNPL
CCCCCCCCCCCCCCEEEEECCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCC
YAQQGNPARKVYGRADNPSNPSPPELHGEVFPYVFTAARLTEHHTAGGMSRQLPYLAELQ
CCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHCCCHHHHCC
PGLFVEVSPQLAAERGLTHMEWAHVITSRAAVDARVFVTDRMRPLRIDDHVVHQIWMPYH
CCEEEEECHHHHHHHCCCHHHHHHHHHHHHHHCEEEEEECCCCCEECCHHHHHHHCCCEE
WGNAGLIDGDVVNDLLGVVADPNVFIQESKVATCDIQPGRRPRGPALLEYIAMYRDRARI
CCCCCCCCHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEE
TVDTGTDLDTTKRSTEHTEET
EEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503; 8522521 [H]