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The map label for this gene is ligC [H]

Identifier: 119871054

GI number: 119871054

Start: 5267034

End: 5268095

Strand: Direct

Name: ligC [H]

Synonym: Mkms_5027

Alternate gene names: 119871054

Gene position: 5267034-5268095 (Clockwise)

Preceding gene: 119871048

Following gene: 119871056

Centisome position: 91.8

GC content: 69.4

Gene sequence:

>1062_bases
GTGCAACTTCCCGTTTCACCCCCGATTGCGCCGATGCTGTCGAAGGCGGTCACGGACATCCCGCTCGGCGCGTCCTACGA
ACCCAAGTGGGACGGGTTCCGGTCGATCGTGTTCCGCGATGGCGACGAGGTGGAACTCGGCAGCCGCAACGAGCGGCCGA
TGACCCGGTACTTCCCCGAACTCGTCGAGGCGGCCCGCGCGGAGCTTCCGGCGCGGTGTGTGATCGACGGCGAGATCGTC
ATCGCCACCGCCGACGGACTGGACTTCGAGGCGCTGCAGTTGCGGTTGCATCCGGCGGCGTCGCGGGTGCGGATGCTGGC
CGAGAAGACGCCGGCGTCGTTCATCGCGTTCGACCTGCTTGCGCTGGGCGACACCGACTATACGTCGCGGCCGTTCGTCG
AACGGCGGGCCGAACTTGAACGCGTGCTCACCGGCGGCCACACATTCCACGTCACGCCGGCCACCGTCGACGTCGACACG
GCACGGCGCTGGTTCCACGAATTCGAGGGCGCCGGCCTCGACGGGGTGATCGCCAAACCGCTCGACGGACCGTATCTGCC
GGACAAGCGGGTGATGTTCAAGGTCAAACACCAGCGCACGGCCGACTGCGTGGTCGCCGGGTACCGGCTGCACAAATCGG
GCGACGACGCCATCGGGTCGCTGCTGCTCGGTCTGTACACCGACGACGGCGAGCTGGCGTCGGTGGGCGTGATCGGGGCG
TTTCCGATGGCGCGGCGGCGGGCCCTGTTCGCCGAGCTGCAGCCGCTGGTGGCCACCTTCGACGAGCATCCGTGGAACTG
GGCCGCCCACGCCGATCCCGACGTGGTGCGCCGCTACGGGGGCGGGTCGCGCTGGAACGCGGGCAAGGATCTGTCGTTCG
TGCCGTTGCGGCCCGAACGGGTGGTCGAGGTGCGGTACGACCACATGGAGGGGCGGCGATTCCGCCACACCGCCCAGTTC
AACCGCTGGCGTCCCGACCGCGACCCGCGCTCGTGCACCTACGCGCAACTCGAGCAGCCGGTCACCTTCCGCCTCGGCGA
CATCGTGCCGGGGCTCGGCTGA

Upstream 100 bases:

>100_bases
GCCGATCCGGCTCCGGTGATGATGTAGTCGTAGCTGGCCATGGGTCGCCTCTCGTCGCGCTGTACGGCCGTATAGTACGT
GTCTCGGCGACAATAGCTGG

Downstream 100 bases:

>100_bases
GTCAGACGGAGACGGCCTGCTTGGCCGCCTGTTTGGCCGCGCGGTTCTCGGCCATCTTGGCTTCGCGTTCGAGGCGGCGC
TGTTTGGCGGTCTCGAATTT

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MQLPVSPPIAPMLSKAVTDIPLGASYEPKWDGFRSIVFRDGDEVELGSRNERPMTRYFPELVEAARAELPARCVIDGEIV
IATADGLDFEALQLRLHPAASRVRMLAEKTPASFIAFDLLALGDTDYTSRPFVERRAELERVLTGGHTFHVTPATVDVDT
ARRWFHEFEGAGLDGVIAKPLDGPYLPDKRVMFKVKHQRTADCVVAGYRLHKSGDDAIGSLLLGLYTDDGELASVGVIGA
FPMARRRALFAELQPLVATFDEHPWNWAAHADPDVVRRYGGGSRWNAGKDLSFVPLRPERVVEVRYDHMEGRRFRHTAQF
NRWRPDRDPRSCTYAQLEQPVTFRLGDIVPGLG

Sequences:

>Translated_353_residues
MQLPVSPPIAPMLSKAVTDIPLGASYEPKWDGFRSIVFRDGDEVELGSRNERPMTRYFPELVEAARAELPARCVIDGEIV
IATADGLDFEALQLRLHPAASRVRMLAEKTPASFIAFDLLALGDTDYTSRPFVERRAELERVLTGGHTFHVTPATVDVDT
ARRWFHEFEGAGLDGVIAKPLDGPYLPDKRVMFKVKHQRTADCVVAGYRLHKSGDDAIGSLLLGLYTDDGELASVGVIGA
FPMARRRALFAELQPLVATFDEHPWNWAAHADPDVVRRYGGGSRWNAGKDLSFVPLRPERVVEVRYDHMEGRRFRHTAQF
NRWRPDRDPRSCTYAQLEQPVTFRLGDIVPGLG
>Mature_353_residues
MQLPVSPPIAPMLSKAVTDIPLGASYEPKWDGFRSIVFRDGDEVELGSRNERPMTRYFPELVEAARAELPARCVIDGEIV
IATADGLDFEALQLRLHPAASRVRMLAEKTPASFIAFDLLALGDTDYTSRPFVERRAELERVLTGGHTFHVTPATVDVDT
ARRWFHEFEGAGLDGVIAKPLDGPYLPDKRVMFKVKHQRTADCVVAGYRLHKSGDDAIGSLLLGLYTDDGELASVGVIGA
FPMARRRALFAELQPLVATFDEHPWNWAAHADPDVVRRYGGGSRWNAGKDLSFVPLRPERVVEVRYDHMEGRRFRHTAQF
NRWRPDRDPRSCTYAQLEQPVTFRLGDIVPGLG

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022865
- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 39518; Mature: 39518

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLPVSPPIAPMLSKAVTDIPLGASYEPKWDGFRSIVFRDGDEVELGSRNERPMTRYFPE
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEECCCCCCCCHHHHHHH
LVEAARAELPARCVIDGEIVIATADGLDFEALQLRLHPAASRVRMLAEKTPASFIAFDLL
HHHHHHHCCCCEEEECCCEEEEECCCCCCEEEEEEECCHHHHHHHHHHHCCHHHHHHHHH
ALGDTDYTSRPFVERRAELERVLTGGHTFHVTPATVDVDTARRWFHEFEGAGLDGVIAKP
HCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCEEEHHHHHHHHHHHCCCCCCCEEECC
LDGPYLPDKRVMFKVKHQRTADCVVAGYRLHKSGDDAIGSLLLGLYTDDGELASVGVIGA
CCCCCCCCCCEEEEECCCCCCCCEEECEEEECCCCHHHHHHHHEEECCCCCEEEEEEEEC
FPMARRRALFAELQPLVATFDEHPWNWAAHADPDVVRRYGGGSRWNAGKDLSFVPLRPER
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEECCCCHH
VVEVRYDHMEGRRFRHTAQFNRWRPDRDPRSCTYAQLEQPVTFRLGDIVPGLG
EEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCEEEECCCCCCCC
>Mature Secondary Structure
MQLPVSPPIAPMLSKAVTDIPLGASYEPKWDGFRSIVFRDGDEVELGSRNERPMTRYFPE
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEECCCCCCCCHHHHHHH
LVEAARAELPARCVIDGEIVIATADGLDFEALQLRLHPAASRVRMLAEKTPASFIAFDLL
HHHHHHHCCCCEEEECCCEEEEECCCCCCEEEEEEECCHHHHHHHHHHHCCHHHHHHHHH
ALGDTDYTSRPFVERRAELERVLTGGHTFHVTPATVDVDTARRWFHEFEGAGLDGVIAKP
HCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCEEEHHHHHHHHHHHCCCCCCCEEECC
LDGPYLPDKRVMFKVKHQRTADCVVAGYRLHKSGDDAIGSLLLGLYTDDGELASVGVIGA
CCCCCCCCCCEEEEECCCCCCCCEEECEEEECCCCHHHHHHHHEEECCCCCEEEEEEEEC
FPMARRRALFAELQPLVATFDEHPWNWAAHADPDVVRRYGGGSRWNAGKDLSFVPLRPER
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEECCCCHH
VVEVRYDHMEGRRFRHTAQFNRWRPDRDPRSCTYAQLEQPVTFRLGDIVPGLG
EEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA