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The map label for this gene is rfbB [C]

Identifier: 119869447

GI number: 119869447

Start: 3581671

End: 3582600

Strand: Direct

Name: rfbB [C]

Synonym: Mkms_3415

Alternate gene names: 119869447

Gene position: 3581671-3582600 (Clockwise)

Preceding gene: 119869446

Following gene: 119869448

Centisome position: 62.43

GC content: 69.46

Gene sequence:

>930_bases
ATGCGCGCCGTCGTCACCGGCGCAGCCGGATTCATCGGGTCCGCGCTGGTGGACCGCCTGCTCGACGATGGGCACCAGGT
GGTCGGGATCGACAACCTGAGCACGGGATCGCTGGCGAACCTCGGATCCGCGTTGCGGCACAGCGCCACCGCCGCACGTC
GATTCACCCTGGTGCGCCGGGACATTCAGGCGCCGGAGCTGACCGACATCATCGCGGGCACCAACCCCGCCGTCATCTTC
CACCTGGCCGCGCACGTGAACTGCGAAGCCTCTTGGGCCGATCCGCATTTCGATGCCCGGAGCAACGTGCTGGGCACGAT
CAACCTCTGCGAGGCCAGCCGGCGCGCCGGGGTCGAGAAGATCGTCTACGCCACCGAGGGCGCGTCGTGTTCGTCCTCGC
CGAGTTCGGTGGCCAAGGCCGCGGGCGAGATGTATCTGCGGGCCTATGCCGAACGGTATGGCCTGGCGCCGATCTGCCTG
GCGATGGCCGGCGTCTACGGGCCGCGTCAGCATCCGGGTGGAGACGCGGGGCTCGTGACGCGTCTGGCGAGCGCGCTGAT
CACCGGCGCTCCGTCTGAGACCTGCCGCGACGACTTCGTCCACCGGGACTTCCTTTTCGTCGACGATGCGGTGGAGGCCC
TGGTGCACGCCGGGTGCACACCGGTCGCGGCAGGCACCTACCACGTGGGCAGCGGACGCCCGACGACTGTGCTGCGCATG
CATCAGATGATCTGCGCGGCAGTCGGGACCACGCGGCCCTGCCTGGTGGTCTCGATGGACGAGTGGAAGGCGGCCGCAGC
AGGAGCCACGAGTACCGCCGGGGAATGGGACTGGACGCCCGCGGTGACTCTCGCCGAGGGGGTCGCCCGCACGGTCGAGT
GGTTGCGAGCGACGCTCGACTCCGACTGTGACCGGCAAGAGGCAGGGTGA

Upstream 100 bases:

>100_bases
GACATCGGCGCTGTTGCTGGGCCGCGACGTGGACAAGCCGCGCAACCTCGCCAAATCGGTGACGGTGGAGTGACGCGATG
ACATCGATCGGAGCTCTCTG

Downstream 100 bases:

>100_bases
GAACGACCGTGTTCAGCCCCTTCAGAAGACGCCCGGACGCCATCCGCGGCACCGACCCTCTGACCGCCGCACCCGGTCCG
GTGTTCTTCGACCGGACGGG

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MRAVVTGAAGFIGSALVDRLLDDGHQVVGIDNLSTGSLANLGSALRHSATAARRFTLVRRDIQAPELTDIIAGTNPAVIF
HLAAHVNCEASWADPHFDARSNVLGTINLCEASRRAGVEKIVYATEGASCSSSPSSVAKAAGEMYLRAYAERYGLAPICL
AMAGVYGPRQHPGGDAGLVTRLASALITGAPSETCRDDFVHRDFLFVDDAVEALVHAGCTPVAAGTYHVGSGRPTTVLRM
HQMICAAVGTTRPCLVVSMDEWKAAAAGATSTAGEWDWTPAVTLAEGVARTVEWLRATLDSDCDRQEAG

Sequences:

>Translated_309_residues
MRAVVTGAAGFIGSALVDRLLDDGHQVVGIDNLSTGSLANLGSALRHSATAARRFTLVRRDIQAPELTDIIAGTNPAVIF
HLAAHVNCEASWADPHFDARSNVLGTINLCEASRRAGVEKIVYATEGASCSSSPSSVAKAAGEMYLRAYAERYGLAPICL
AMAGVYGPRQHPGGDAGLVTRLASALITGAPSETCRDDFVHRDFLFVDDAVEALVHAGCTPVAAGTYHVGSGRPTTVLRM
HQMICAAVGTTRPCLVVSMDEWKAAAAGATSTAGEWDWTPAVTLAEGVARTVEWLRATLDSDCDRQEAG
>Mature_309_residues
MRAVVTGAAGFIGSALVDRLLDDGHQVVGIDNLSTGSLANLGSALRHSATAARRFTLVRRDIQAPELTDIIAGTNPAVIF
HLAAHVNCEASWADPHFDARSNVLGTINLCEASRRAGVEKIVYATEGASCSSSPSSVAKAAGEMYLRAYAERYGLAPICL
AMAGVYGPRQHPGGDAGLVTRLASALITGAPSETCRDDFVHRDFLFVDDAVEALVHAGCTPVAAGTYHVGSGRPTTVLRM
HQMICAAVGTTRPCLVVSMDEWKAAAAGATSTAGEWDWTPAVTLAEGVARTVEWLRATLDSDCDRQEAG

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=326, Percent_Identity=23.9263803680982, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI7657641, Length=336, Percent_Identity=22.6190476190476, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17539532, Length=323, Percent_Identity=23.2198142414861, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17568069, Length=272, Percent_Identity=24.2647058823529, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21356223, Length=332, Percent_Identity=24.0963855421687, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 32391; Mature: 32391

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVVTGAAGFIGSALVDRLLDDGHQVVGIDNLSTGSLANLGSALRHSATAARRFTLVRR
CCEEEECHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DIQAPELTDIIAGTNPAVIFHLAAHVNCEASWADPHFDARSNVLGTINLCEASRRAGVEK
HCCCCCHHHHHCCCCCEEEEEEEHHCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCEE
IVYATEGASCSSSPSSVAKAAGEMYLRAYAERYGLAPICLAMAGVYGPRQHPGGDAGLVT
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHH
RLASALITGAPSETCRDDFVHRDFLFVDDAVEALVHAGCTPVAAGTYHVGSGRPTTVLRM
HHHHHHHCCCCCHHHHHHHHHHHHEEHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHH
HQMICAAVGTTRPCLVVSMDEWKAAAAGATSTAGEWDWTPAVTLAEGVARTVEWLRATLD
HHHHHHHHCCCCCEEEEECHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
SDCDRQEAG
CCCCCCCCC
>Mature Secondary Structure
MRAVVTGAAGFIGSALVDRLLDDGHQVVGIDNLSTGSLANLGSALRHSATAARRFTLVRR
CCEEEECHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DIQAPELTDIIAGTNPAVIFHLAAHVNCEASWADPHFDARSNVLGTINLCEASRRAGVEK
HCCCCCHHHHHCCCCCEEEEEEEHHCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCEE
IVYATEGASCSSSPSSVAKAAGEMYLRAYAERYGLAPICLAMAGVYGPRQHPGGDAGLVT
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHH
RLASALITGAPSETCRDDFVHRDFLFVDDAVEALVHAGCTPVAAGTYHVGSGRPTTVLRM
HHHHHHHCCCCCHHHHHHHHHHHHEEHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHH
HQMICAAVGTTRPCLVVSMDEWKAAAAGATSTAGEWDWTPAVTLAEGVARTVEWLRATLD
HHHHHHHHCCCCCEEEEECHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
SDCDRQEAG
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]