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The map label for this gene is yngI [H]

Identifier: 119867847

GI number: 119867847

Start: 1917973

End: 1919541

Strand: Reverse

Name: yngI [H]

Synonym: Mkms_1808

Alternate gene names: 119867847

Gene position: 1919541-1917973 (Counterclockwise)

Preceding gene: 119867848

Following gene: 119867842

Centisome position: 33.46

GC content: 72.02

Gene sequence:

>1569_bases
ATGTCCAACGCTGACACCACGATCGACCGGTTGCTGCGCCGCAACACCGCCGCCCATCCGGAGAAGGCCGCCGTCATCGA
CCCGGCGTCCCGGGTGTCCCACGGCGACCTCGACCGCATCACCCGCACGCTGGCCGCGGCCCTCGTCGGCGCCGGTGTCG
GCAAGGGGTCGCGGGTCGGGCTCGTCATGCCCAACAGCGTGCAGTGGGTGCAGATCGCGGTGGCCCTGACCCGGATCGGC
GCGGTACTCGTGCCGCTGAGCACGCTGCTGGCGCCGCGTGAGCTGGTGGCGCAGCTGCGCACGGCGGCGGTGCAGGTGCT
GGTCACCGTCGAGGAGTTCCGCGGCCACCGCTACCTCGCCGACCTGCGGGCCGAACTGGGTCTGCCGGACCTCGACGACC
CGCTCCACAGCCCCGAACTGCCTGCGCTACGGCAGGTCTGGAGCCCGGACCAGCTCATGGCGGCCCGGGCCGTCGACCAC
GAACTGGTGGACGCGCTCACCGACGCGGTGACCCCCGGCGACACGCTCGCGATCATGTTCACCTCCGGCAGCAGCGGCCC
GCCCAAGGGGGTGGTGCACTCGCACGGCAACGCGCTCGGAGCCGTCGCCGCGGGTCTGCACGCCCGCTGCATCGATGCCG
ACACCCGGCTGTATCTGCCGATGCCGTTCTTCTGGGTCGGCGGGTTCGGCAGCGGGGTGCTCTCGGCGCTGGTGGCCGGT
GCGACGCTGGTGACCGAGCAGATCCCGCAACCGGAGTCCACGCTGCGGTTACTGGAGGCCGAACGCGTCACGCTGTTCCG
TGGCTGGCCCGATCAGGCCGAAGCGCTGGCGCGGCAACGACATTCGGTCGGGGCGGATCTGTCGTCGCTGCGGCCGGGCA
GCCTCGAGGCGCTGTTGCCACCCGATCAGCGGGGCCGGCCGGGAGCACGCGCCAGACTGTTCGGGATGACCGAGGCGTTC
GGGCCGTACTGCGGCTACCGCGCCGACGCCGATATGCCGGAAACCGCCTGGGGTAGCTGCGGCCGACCGTTCGACGGGAT
GGAGGTCCGCATCGTCGACCCCGAGACGGCTGCACCCGTGCCGGCCGGCCGGATCGGTGAGATCCAGATCCGCGGACCGC
ATGTCATGCGCGGCGTCTGCCGGCGCAGCCGCGAGGAGGTCTTCACCGCCGACGGGTTCTATCCCACCGGTGACCTCGGC
CATCTCGACGACCGCGGATTCATGTTCTACCACGGGCGATCCGACGACATGTTCAAGGTCAGCGGCGCCACGGTCTACCC
CAGCGAGGTCGAGGCGGCCCTGCGCACCCTCGACGGGGTCGCCGCCGCCTTCGTCACCGACGTGCCCGACGCCGGCGTCG
ACCGGGTGGGGGCGGCGGTGGTCTGCGACCGCCCGACGACGGTGGGGGCGCTGCGGTCGGCGGCCAAGAACGTGCTCAGC
GCGTTCAAGGTGCCGACGATATGGCTGCTGCTCGACGACGATGACGCCGTCCCGCGCAAGGCGACCGGCAAGGTCGACGT
GCGCGCGCTCCGGGAGCTACTGGCCGCCTCGTCCGGCGAGCAGACGTGA

Upstream 100 bases:

>100_bases
GCGTACAAGATCCCCCGCCGCATCACCGCGCTCACCCGCGACGACCTGCCCGTGATGGCGAGCGGCAAGGTCGACCTCCC
CCGGCTCACGAAGGTGTTCG

Downstream 100 bases:

>100_bases
ATGTCCCCCATTCCGGCCGAATTCGGGGACATTTGTGTCTGCTCGCGGAGTCACTGGACCACGCCGCGGGTCTTGAGGTG
CTCGATGAGCGGTTCGGCGC

Product: AMP-dependent synthetase and ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 521

Protein sequence:

>522_residues
MSNADTTIDRLLRRNTAAHPEKAAVIDPASRVSHGDLDRITRTLAAALVGAGVGKGSRVGLVMPNSVQWVQIAVALTRIG
AVLVPLSTLLAPRELVAQLRTAAVQVLVTVEEFRGHRYLADLRAELGLPDLDDPLHSPELPALRQVWSPDQLMAARAVDH
ELVDALTDAVTPGDTLAIMFTSGSSGPPKGVVHSHGNALGAVAAGLHARCIDADTRLYLPMPFFWVGGFGSGVLSALVAG
ATLVTEQIPQPESTLRLLEAERVTLFRGWPDQAEALARQRHSVGADLSSLRPGSLEALLPPDQRGRPGARARLFGMTEAF
GPYCGYRADADMPETAWGSCGRPFDGMEVRIVDPETAAPVPAGRIGEIQIRGPHVMRGVCRRSREEVFTADGFYPTGDLG
HLDDRGFMFYHGRSDDMFKVSGATVYPSEVEAALRTLDGVAAAFVTDVPDAGVDRVGAAVVCDRPTTVGALRSAAKNVLS
AFKVPTIWLLLDDDDAVPRKATGKVDVRALRELLAASSGEQT

Sequences:

>Translated_522_residues
MSNADTTIDRLLRRNTAAHPEKAAVIDPASRVSHGDLDRITRTLAAALVGAGVGKGSRVGLVMPNSVQWVQIAVALTRIG
AVLVPLSTLLAPRELVAQLRTAAVQVLVTVEEFRGHRYLADLRAELGLPDLDDPLHSPELPALRQVWSPDQLMAARAVDH
ELVDALTDAVTPGDTLAIMFTSGSSGPPKGVVHSHGNALGAVAAGLHARCIDADTRLYLPMPFFWVGGFGSGVLSALVAG
ATLVTEQIPQPESTLRLLEAERVTLFRGWPDQAEALARQRHSVGADLSSLRPGSLEALLPPDQRGRPGARARLFGMTEAF
GPYCGYRADADMPETAWGSCGRPFDGMEVRIVDPETAAPVPAGRIGEIQIRGPHVMRGVCRRSREEVFTADGFYPTGDLG
HLDDRGFMFYHGRSDDMFKVSGATVYPSEVEAALRTLDGVAAAFVTDVPDAGVDRVGAAVVCDRPTTVGALRSAAKNVLS
AFKVPTIWLLLDDDDAVPRKATGKVDVRALRELLAASSGEQT
>Mature_521_residues
SNADTTIDRLLRRNTAAHPEKAAVIDPASRVSHGDLDRITRTLAAALVGAGVGKGSRVGLVMPNSVQWVQIAVALTRIGA
VLVPLSTLLAPRELVAQLRTAAVQVLVTVEEFRGHRYLADLRAELGLPDLDDPLHSPELPALRQVWSPDQLMAARAVDHE
LVDALTDAVTPGDTLAIMFTSGSSGPPKGVVHSHGNALGAVAAGLHARCIDADTRLYLPMPFFWVGGFGSGVLSALVAGA
TLVTEQIPQPESTLRLLEAERVTLFRGWPDQAEALARQRHSVGADLSSLRPGSLEALLPPDQRGRPGARARLFGMTEAFG
PYCGYRADADMPETAWGSCGRPFDGMEVRIVDPETAAPVPAGRIGEIQIRGPHVMRGVCRRSREEVFTADGFYPTGDLGH
LDDRGFMFYHGRSDDMFKVSGATVYPSEVEAALRTLDGVAAAFVTDVPDAGVDRVGAAVVCDRPTTVGALRSAAKNVLSA
FKVPTIWLLLDDDDAVPRKATGKVDVRALRELLAASSGEQT

Specific function: Unknown

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=546, Percent_Identity=26.7399267399267, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI42544132, Length=520, Percent_Identity=25.3846153846154, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI115511026, Length=515, Percent_Identity=23.6893203883495, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI38505220, Length=510, Percent_Identity=24.3137254901961, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI122937307, Length=525, Percent_Identity=23.8095238095238, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI187761345, Length=378, Percent_Identity=27.5132275132275, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI187761343, Length=378, Percent_Identity=27.5132275132275, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI13236579, Length=462, Percent_Identity=25.1082251082251, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI145693145, Length=529, Percent_Identity=25.8979206049149, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788107, Length=549, Percent_Identity=24.7723132969035, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI221142682, Length=499, Percent_Identity=26.4529058116232, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1790505, Length=588, Percent_Identity=24.3197278911565, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786810, Length=537, Percent_Identity=25.8845437616387, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71994703, Length=519, Percent_Identity=26.9749518304432, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71994694, Length=519, Percent_Identity=26.9749518304432, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71994690, Length=523, Percent_Identity=27.151051625239, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17560308, Length=551, Percent_Identity=25.4083484573503, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32563687, Length=517, Percent_Identity=24.7582205029014, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17559526, Length=515, Percent_Identity=25.0485436893204, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17558820, Length=519, Percent_Identity=23.8921001926782, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17557194, Length=546, Percent_Identity=22.8937728937729, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17538037, Length=555, Percent_Identity=22.7027027027027, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71985884, Length=382, Percent_Identity=25.6544502617801, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531443, Length=368, Percent_Identity=25, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319264, Length=574, Percent_Identity=24.0418118466899, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6319699, Length=366, Percent_Identity=25.1366120218579, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24581924, Length=535, Percent_Identity=26.5420560747664, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21355181, Length=502, Percent_Identity=25.0996015936255, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281364798, Length=548, Percent_Identity=23.7226277372263, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24583465, Length=548, Percent_Identity=23.7226277372263, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24583463, Length=548, Percent_Identity=23.7226277372263, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24656500, Length=516, Percent_Identity=23.062015503876, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21358303, Length=305, Percent_Identity=25.9016393442623, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI45552801, Length=552, Percent_Identity=23.0072463768116, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45550496, Length=553, Percent_Identity=23.1464737793852, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24648255, Length=493, Percent_Identity=22.5152129817444, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648253, Length=493, Percent_Identity=22.1095334685598, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24653035, Length=498, Percent_Identity=21.4859437751004, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648260, Length=473, Percent_Identity=23.8900634249471, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356441, Length=310, Percent_Identity=25.1612903225806, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161076582, Length=558, Percent_Identity=21.326164874552, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI19922652, Length=295, Percent_Identity=24.406779661017, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281365686, Length=302, Percent_Identity=23.841059602649, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: NA

Molecular weight: Translated: 55593; Mature: 55462

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNADTTIDRLLRRNTAAHPEKAAVIDPASRVSHGDLDRITRTLAAALVGAGVGKGSRVG
CCCCHHHHHHHHHHCCCCCCCCCEEECCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
LVMPNSVQWVQIAVALTRIGAVLVPLSTLLAPRELVAQLRTAAVQVLVTVEEFRGHRYLA
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHEEHHHHCCCHHHH
DLRAELGLPDLDDPLHSPELPALRQVWSPDQLMAARAVDHELVDALTDAVTPGDTLAIMF
HHHHHCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
TSGSSGPPKGVVHSHGNALGAVAAGLHARCIDADTRLYLPMPFFWVGGFGSGVLSALVAG
ECCCCCCCCCCEECCCCHHHHHHHCCHHEEECCCCEEEECCCCEEECCCHHHHHHHHHHH
ATLVTEQIPQPESTLRLLEAERVTLFRGWPDQAEALARQRHSVGADLSSLRPGSLEALLP
HHHHHHHCCCCHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHCCCCHHHCCCCCCEEECC
PDQRGRPGARARLFGMTEAFGPYCGYRADADMPETAWGSCGRPFDGMEVRIVDPETAAPV
CCCCCCCCCCEEEEECHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCC
PAGRIGEIQIRGPHVMRGVCRRSREEVFTADGFYPTGDLGHLDDRGFMFYHGRSDDMFKV
CCCCCCEEEECCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEEECCCCCEEEE
SGATVYPSEVEAALRTLDGVAAAFVTDVPDAGVDRVGAAVVCDRPTTVGALRSAAKNVLS
CCCEECHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEEECCCCHHHHHHHHHHHHHH
AFKVPTIWLLLDDDDAVPRKATGKVDVRALRELLAASSGEQT
HHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SNADTTIDRLLRRNTAAHPEKAAVIDPASRVSHGDLDRITRTLAAALVGAGVGKGSRVG
CCCHHHHHHHHHHCCCCCCCCCEEECCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
LVMPNSVQWVQIAVALTRIGAVLVPLSTLLAPRELVAQLRTAAVQVLVTVEEFRGHRYLA
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHEEHHHHCCCHHHH
DLRAELGLPDLDDPLHSPELPALRQVWSPDQLMAARAVDHELVDALTDAVTPGDTLAIMF
HHHHHCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
TSGSSGPPKGVVHSHGNALGAVAAGLHARCIDADTRLYLPMPFFWVGGFGSGVLSALVAG
ECCCCCCCCCCEECCCCHHHHHHHCCHHEEECCCCEEEECCCCEEECCCHHHHHHHHHHH
ATLVTEQIPQPESTLRLLEAERVTLFRGWPDQAEALARQRHSVGADLSSLRPGSLEALLP
HHHHHHHCCCCHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHCCCCHHHCCCCCCEEECC
PDQRGRPGARARLFGMTEAFGPYCGYRADADMPETAWGSCGRPFDGMEVRIVDPETAAPV
CCCCCCCCCCEEEEECHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCC
PAGRIGEIQIRGPHVMRGVCRRSREEVFTADGFYPTGDLGHLDDRGFMFYHGRSDDMFKV
CCCCCCEEEECCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEEECCCCCEEEE
SGATVYPSEVEAALRTLDGVAAAFVTDVPDAGVDRVGAAVVCDRPTTVGALRSAAKNVLS
CCCEECHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEEECCCCHHHHHHHHHHHHHH
AFKVPTIWLLLDDDDAVPRKATGKVDVRALRELLAASSGEQT
HHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]