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The map label for this gene is mtrA [H]

Identifier: 119867415

GI number: 119867415

Start: 1461694

End: 1462380

Strand: Direct

Name: mtrA [H]

Synonym: Mkms_1365

Alternate gene names: 119867415

Gene position: 1461694-1462380 (Clockwise)

Preceding gene: 119867414

Following gene: 119867416

Centisome position: 25.48

GC content: 64.48

Gene sequence:

>687_bases
ATGGACTCCATGAGGCAAAGGATTCTGGTCGTCGATGACGATCCCTCGCTGGCCGAGATGCTCACCATCGTGCTGCGCGG
GGAAGGATTCGACACCGCCGTCGTCGGCGACGGCACCCAGGCGCTCAGCGCCGTGCGGGAACTGCGCCCGGATCTGGTGT
TGCTGGATCTGATGCTGCCCGGCATGAACGGCATCGACGTCTGCCGGGTGCTGCGTGCGGATTCCGGTGTGCCCATCGTG
ATGCTCACCGCGAAGACCGACACCGTCGACGTCGTCCTCGGCCTGGAATCCGGTGCCGACGACTACGTGATGAAGCCGTT
CAAACCCAAGGAACTCGTCGCCCGCGTGCGTGCCCGGTTGCGCCGCAACGAGGACGAGCCCGCGGAGTTGCTGTCGATCG
GCGACGTGGAGATCGACGTCCCCGCCCACAAGGTGACCCGGCAGGGTGAGCAGATTTCGCTGACACCGCTGGAGTTCGAC
CTGTTGGTGGCGCTGGCACGTAAACCGCGCCAGGTGTTTACTCGAGATGTGCTGCTCGAACAGGTGTGGGGATACCGTCA
CCCCGCGGACACCCGTTTGGTGAACGTGCATGTCCAGCGGTTGCGGGCCAAGGTCGAGAAGGACCCGGAGAACCCGCAGG
TGGTGTTGACCGTTCGAGGAGTGGGATACAAGGCCGGACCTCCGTGA

Upstream 100 bases:

>100_bases
GTCGACGCGGCGGCGCTGGCCGACGGATTGACCGCTTCCTGAGGTCAACCGGAGAAACGCCCTGCGTGGTAGCCGGGTTT
TATCGCGATCTGGTGACACC

Downstream 100 bases:

>100_bases
CGATTCACCGCTCCGCGGTGGCCGTGACGATTCACCGCTCCGCGGTGGCCGTGACCCTCACCGCTCGGCGGCGGTCGTGA
TCTGGGGCGCACGACGGCGG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MDSMRQRILVVDDDPSLAEMLTIVLRGEGFDTAVVGDGTQALSAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIV
MLTAKTDTVDVVLGLESGADDYVMKPFKPKELVARVRARLRRNEDEPAELLSIGDVEIDVPAHKVTRQGEQISLTPLEFD
LLVALARKPRQVFTRDVLLEQVWGYRHPADTRLVNVHVQRLRAKVEKDPENPQVVLTVRGVGYKAGPP

Sequences:

>Translated_228_residues
MDSMRQRILVVDDDPSLAEMLTIVLRGEGFDTAVVGDGTQALSAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIV
MLTAKTDTVDVVLGLESGADDYVMKPFKPKELVARVRARLRRNEDEPAELLSIGDVEIDVPAHKVTRQGEQISLTPLEFD
LLVALARKPRQVFTRDVLLEQVWGYRHPADTRLVNVHVQRLRAKVEKDPENPQVVLTVRGVGYKAGPP
>Mature_228_residues
MDSMRQRILVVDDDPSLAEMLTIVLRGEGFDTAVVGDGTQALSAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIV
MLTAKTDTVDVVLGLESGADDYVMKPFKPKELVARVRARLRRNEDEPAELLSIGDVEIDVPAHKVTRQGEQISLTPLEFD
LLVALARKPRQVFTRDVLLEQVWGYRHPADTRLVNVHVQRLRAKVEKDPENPQVVLTVRGVGYKAGPP

Specific function: Member of the two-component regulatory system mtrA/mtrB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=40.3508771929825, Blast_Score=167, Evalue=4e-43,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=40.8888888888889, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=40.4444444444444, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=40.625, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=38.0733944954128, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=37.219730941704, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=36.0730593607306, Blast_Score=143, Evalue=7e-36,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=38.0530973451327, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=32.15859030837, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=33.4862385321101, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=34.841628959276, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=33.7719298245614, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=35.7758620689655, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=32.8767123287671, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=36.1111111111111, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790437, Length=123, Percent_Identity=37.3983739837398, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790299, Length=120, Percent_Identity=30.8333333333333, Blast_Score=67, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6322000, Length=102, Percent_Identity=32.3529411764706, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25273; Mature: 25273

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSMRQRILVVDDDPSLAEMLTIVLRGEGFDTAVVGDGTQALSAVRELRPDLVLLDLMLP
CCCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCEEEEEHHHC
GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYVMKPFKPKELVARVRARL
CCCHHHHHHHHHCCCCCCEEEEEECCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
RRNEDEPAELLSIGDVEIDVPAHKVTRQGEQISLTPLEFDLLVALARKPRQVFTRDVLLE
HCCCCCHHHHEEECCEEEECCHHHHHCCCCEEEECCHHHHHHHHHHHCCHHHHHHHHHHH
QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPQVVLTVRGVGYKAGPP
HHHCCCCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MDSMRQRILVVDDDPSLAEMLTIVLRGEGFDTAVVGDGTQALSAVRELRPDLVLLDLMLP
CCCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCEEEEEHHHC
GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYVMKPFKPKELVARVRARL
CCCHHHHHHHHHCCCCCCEEEEEECCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
RRNEDEPAELLSIGDVEIDVPAHKVTRQGEQISLTPLEFDLLVALARKPRQVFTRDVLLE
HCCCCCHHHHEEECCEEEECCHHHHHCCCCEEEECCHHHHHHHHHHHCCHHHHHHHHHHH
QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPQVVLTVRGVGYKAGPP
HHHCCCCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]