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The map label for this gene is yfnA [H]

Identifier: 119867399

GI number: 119867399

Start: 1443704

End: 1445176

Strand: Direct

Name: yfnA [H]

Synonym: Mkms_1349

Alternate gene names: 119867399

Gene position: 1443704-1445176 (Clockwise)

Preceding gene: 119867397

Following gene: 119867400

Centisome position: 25.16

GC content: 66.73

Gene sequence:

>1473_bases
ATGGCCGGCAGATGGCGCACGAAATCAGTCGAGCAGTCGATCGCCGACACCGACGAACCAGGGACCAGGCTCCGCAAGGA
TCTGAGCTGGTGGGATCTGACCGTGTTCGGTGTGTCGGTGGTGATCGGCGCAGGCATCTTCACCATCACCGCGTCGACGG
CGGGCAATCTCACCGGCCCGGCGATCTCGATCTCGTTCGTACTCGCCGCCATCGCGTGCGGTCTGGCGGCCCTCTGCTAC
GCCGAATTCGCCTCGACGGTGCCCGTCGCGGGCAGCGCCTACACGTTCTCCTACGCCACCTTCGGCGAATTCGTCGCCTG
GATCATCGGGTGGGATCTGATCCTCGAGTTCGCCGTGGCCGCCGCGGTGGTGGCCAAGGGTTGGTCGAGTTATCTGGGCA
CGGTGTTCGGCTTCGGCGGCGGGGTCGCGAACTTCGGCGGTTTCGAGGTGGACTGGGGAGCGCTGGTGATCATCGCCGTC
GTCACCCTGCTGTTGGCCCGTGGGACGAAACTCTCCGCCGAAGTCAGCCTCATCATCACCGTCATCAAGGTCGCGGTGGT
GCTGTTGGTGGTCATCGTCGGTTCGTTCTTCATCAAGGCCGCCAACTACTCGCCGTTCATCCCGCCCGCCGAATCCGGCG
AGGGCGGCACGGGTACCGAGCAGTCGCTGTTCTCGTTGATCACCGGCGCGGAGGGCAGCGCCTACGGCTGGTACGGGCTG
CTCGCCGGTGCGTCGATCGTGTTCTTCGCGTTCATCGGATTCGACATCGTGGCCACCACCGCGGAGGAGACCAAGAACCC
GCAGCGCGACGTCCCCCGCGGGATCCTGTCGTCGCTGGCGATCGTCACCGTCTTGTACGTGGCCGTCGCCGTGGTCCTGT
CCGGCATGGTGTCCTACACCGAACTCCGCGATGCGGGCAGCGGGGCGAACCTCGCGACGGCGTTCGCGGCCAACGGGGTG
GACTGGGCCGCGACCGTCATCTCCATCGGCGCACTGGCCGGTCTGACGACCGTGGTGATCGTGCTGATGCTGGGGCAGAC
GCGCGTGCTGTTCGCGATGTCGCGCGACGCCCTGCTGCCGCGTCAACTGGCCCAGACCGGTGAGCACGGCACACCGGTGC
GGATCACCGTGATCGTCGGCGTGGTCGTGGCCGTCGCCGCGACGGTGTTCCCGATCGGCAAGCTGGAGGAGATGGTCAAC
ATCGGCACGCTGTTCGCGTTCGTGCTGGTGTCGGCCGGGGTGATCGTGCTGCGGCGCACGCGCCCGGATCTCAAGCGCGG
CTTCAAGGCGCCGTTCGTGCCGCTGCTGCCGATCGCCGCGATCATCGCCTGTGTGTGGCTGATGTTGAACCTGACGGGGC
TGACCTGGATCCGCTTCCTCATCTGGATGGCGATCGGCGTGGTCGTGTACTTCCTTTACGGCCGCAGGCACTCGCTCGTC
GGCCGGCGCGAGCAGGAGGCCGTCACCGAGTGA

Upstream 100 bases:

>100_bases
CGCGTGTTTAGTACTCCGCCCCATCGGTGCACAGTACTCGGTACATTCCCCGAATCCAGGCCCTAACTCGCATTGCGACC
CCATCCGAAAGGGAAACGTC

Downstream 100 bases:

>100_bases
GGCCGTTTTACAAAATGGCGTCTAGTGTCTAGACAGCGGACAAAACCACTCCTATAGTCAAGTCATCGTCGTGATGACTT
CACTAGGAGGTGGCTGTGAC

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MAGRWRTKSVEQSIADTDEPGTRLRKDLSWWDLTVFGVSVVIGAGIFTITASTAGNLTGPAISISFVLAAIACGLAALCY
AEFASTVPVAGSAYTFSYATFGEFVAWIIGWDLILEFAVAAAVVAKGWSSYLGTVFGFGGGVANFGGFEVDWGALVIIAV
VTLLLARGTKLSAEVSLIITVIKVAVVLLVVIVGSFFIKAANYSPFIPPAESGEGGTGTEQSLFSLITGAEGSAYGWYGL
LAGASIVFFAFIGFDIVATTAEETKNPQRDVPRGILSSLAIVTVLYVAVAVVLSGMVSYTELRDAGSGANLATAFAANGV
DWAATVISIGALAGLTTVVIVLMLGQTRVLFAMSRDALLPRQLAQTGEHGTPVRITVIVGVVVAVAATVFPIGKLEEMVN
IGTLFAFVLVSAGVIVLRRTRPDLKRGFKAPFVPLLPIAAIIACVWLMLNLTGLTWIRFLIWMAIGVVVYFLYGRRHSLV
GRREQEAVTE

Sequences:

>Translated_490_residues
MAGRWRTKSVEQSIADTDEPGTRLRKDLSWWDLTVFGVSVVIGAGIFTITASTAGNLTGPAISISFVLAAIACGLAALCY
AEFASTVPVAGSAYTFSYATFGEFVAWIIGWDLILEFAVAAAVVAKGWSSYLGTVFGFGGGVANFGGFEVDWGALVIIAV
VTLLLARGTKLSAEVSLIITVIKVAVVLLVVIVGSFFIKAANYSPFIPPAESGEGGTGTEQSLFSLITGAEGSAYGWYGL
LAGASIVFFAFIGFDIVATTAEETKNPQRDVPRGILSSLAIVTVLYVAVAVVLSGMVSYTELRDAGSGANLATAFAANGV
DWAATVISIGALAGLTTVVIVLMLGQTRVLFAMSRDALLPRQLAQTGEHGTPVRITVIVGVVVAVAATVFPIGKLEEMVN
IGTLFAFVLVSAGVIVLRRTRPDLKRGFKAPFVPLLPIAAIIACVWLMLNLTGLTWIRFLIWMAIGVVVYFLYGRRHSLV
GRREQEAVTE
>Mature_489_residues
AGRWRTKSVEQSIADTDEPGTRLRKDLSWWDLTVFGVSVVIGAGIFTITASTAGNLTGPAISISFVLAAIACGLAALCYA
EFASTVPVAGSAYTFSYATFGEFVAWIIGWDLILEFAVAAAVVAKGWSSYLGTVFGFGGGVANFGGFEVDWGALVIIAVV
TLLLARGTKLSAEVSLIITVIKVAVVLLVVIVGSFFIKAANYSPFIPPAESGEGGTGTEQSLFSLITGAEGSAYGWYGLL
AGASIVFFAFIGFDIVATTAEETKNPQRDVPRGILSSLAIVTVLYVAVAVVLSGMVSYTELRDAGSGANLATAFAANGVD
WAATVISIGALAGLTTVVIVLMLGQTRVLFAMSRDALLPRQLAQTGEHGTPVRITVIVGVVVAVAATVFPIGKLEEMVNI
GTLFAFVLVSAGVIVLRRTRPDLKRGFKAPFVPLLPIAAIIACVWLMLNLTGLTWIRFLIWMAIGVVVYFLYGRRHSLVG
RREQEAVTE

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258645169, Length=423, Percent_Identity=36.6430260047281, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI181337167, Length=446, Percent_Identity=35.8744394618834, Blast_Score=219, Evalue=6e-57,
Organism=Homo sapiens, GI258614003, Length=424, Percent_Identity=35.8490566037736, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI258614005, Length=424, Percent_Identity=35.8490566037736, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI4507047, Length=441, Percent_Identity=34.2403628117914, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI114326544, Length=434, Percent_Identity=36.6359447004608, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI114326550, Length=434, Percent_Identity=36.6359447004608, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI110347453, Length=429, Percent_Identity=33.7995337995338, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI186910308, Length=500, Percent_Identity=26.2, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI186910306, Length=500, Percent_Identity=26.2, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI186910304, Length=500, Percent_Identity=26.2, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI187423910, Length=491, Percent_Identity=24.6435845213849, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI7657591, Length=491, Percent_Identity=24.6435845213849, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI115648063, Length=491, Percent_Identity=24.6435845213849, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI115648022, Length=491, Percent_Identity=24.6435845213849, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI7657683, Length=375, Percent_Identity=23.4666666666667, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI87081869, Length=476, Percent_Identity=24.1596638655462, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1790653, Length=438, Percent_Identity=23.0593607305936, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI87081708, Length=496, Percent_Identity=21.1693548387097, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786302, Length=378, Percent_Identity=21.4285714285714, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI87082023, Length=461, Percent_Identity=24.295010845987, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786789, Length=420, Percent_Identity=22.3809523809524, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1786602, Length=424, Percent_Identity=22.1698113207547, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786694, Length=437, Percent_Identity=24.4851258581236, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI87081915, Length=415, Percent_Identity=23.3734939759036, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788480, Length=460, Percent_Identity=23.2608695652174, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI48994972, Length=468, Percent_Identity=23.2905982905983, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082250, Length=477, Percent_Identity=23.8993710691824, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI2367353, Length=353, Percent_Identity=24.3626062322946, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=413, Percent_Identity=37.5302663438257, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17531343, Length=427, Percent_Identity=33.4894613583138, Blast_Score=204, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI17533459, Length=412, Percent_Identity=33.252427184466, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI193208714, Length=427, Percent_Identity=23.1850117096019, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17537453, Length=362, Percent_Identity=23.2044198895028, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32566695, Length=427, Percent_Identity=23.1850117096019, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32566699, Length=365, Percent_Identity=23.2876712328767, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71993915, Length=403, Percent_Identity=24.0694789081886, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71982612, Length=447, Percent_Identity=23.0425055928412, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71982608, Length=447, Percent_Identity=23.0425055928412, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17568033, Length=457, Percent_Identity=21.0065645514223, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17540018, Length=444, Percent_Identity=22.5225225225225, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24666159, Length=435, Percent_Identity=36.551724137931, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI221512776, Length=435, Percent_Identity=36.551724137931, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24667468, Length=428, Percent_Identity=37.1495327102804, Blast_Score=239, Evalue=5e-63,
Organism=Drosophila melanogaster, GI24668806, Length=448, Percent_Identity=33.4821428571429, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI21356285, Length=448, Percent_Identity=33.4821428571429, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24668802, Length=448, Percent_Identity=33.4821428571429, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI161077963, Length=425, Percent_Identity=34.1176470588235, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI281366235, Length=425, Percent_Identity=32.4705882352941, Blast_Score=188, Evalue=9e-48,
Organism=Drosophila melanogaster, GI116007820, Length=425, Percent_Identity=32.4705882352941, Blast_Score=188, Evalue=9e-48,
Organism=Drosophila melanogaster, GI116007818, Length=423, Percent_Identity=32.8605200945626, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI85725152, Length=423, Percent_Identity=32.8605200945626, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI21357367, Length=440, Percent_Identity=22.7272727272727, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI221331183, Length=453, Percent_Identity=24.0618101545254, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17647653, Length=453, Percent_Identity=24.0618101545254, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24664379, Length=453, Percent_Identity=24.0618101545254, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45550968, Length=455, Percent_Identity=23.5164835164835, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19921172, Length=455, Percent_Identity=23.5164835164835, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24651635, Length=415, Percent_Identity=23.6144578313253, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24651633, Length=415, Percent_Identity=23.6144578313253, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51597; Mature: 51466

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHCCC
>Mature Secondary Structure 
AGRWRTKSVEQSIADTDEPGTRLRKDLSWWDLTVFGVSVVIGAGIFTITASTAGNLTGP
CCCCCCHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCHHHEEEECCCCCCCCH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CCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]