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The map label for this gene is erg3 [H]

Identifier: 119775682

GI number: 119775682

Start: 3058695

End: 3059558

Strand: Reverse

Name: erg3 [H]

Synonym: Sama_2550

Alternate gene names: 119775682

Gene position: 3059558-3058695 (Counterclockwise)

Preceding gene: 119775683

Following gene: 119775681

Centisome position: 71.05

GC content: 52.55

Gene sequence:

>864_bases
ATGAACCTCGACAAGCTAATTGCCCATCCGGAGCTGCTGCTGATAGTGTTGGCGCCGATTTTTTTTCTGTGCATGGCGCT
GGAGTTTGTGGTCGCCAATGTGCGTAAGCGACTGCCGGAAAATGCCAGATACAGTAAAGCAGAGCTCCTGTGTAACCTCA
GTCTGGCGGGAATGCACCAGGCTGCCGATCTGCTGAGCGGATTTCTGATTGCCAAACTGTACCTGTATTTTTTTGGTTGG
CGGCTGTTCGATATTGAAATGAATGGGCTTAATTTTGTGTTGCTGCTGCTGGCACAGGATTTTTGCTATTACTGGTTCCA
TCGTTGCAGCCACCGATGCCGCTGGATGTGGGCCGCTCATGTGGCTCATCACAGCTCAGAAAACATGAACTTTTCCACCG
CTTTCAGACAAAGCCTGATGTACCCGCTGGCGGGAATGTGGATATTCTGGTTGCCTCTGGTTGTGATTGGTTTCGACCCT
GCCTGGGTCGTGTTTGCGGTGCTGGCAAGCCTTGGGTTTCAGTTTTTTGTACATACCCAGCTGGTGGATAAACTTGGCCC
GCTGGAATGGGTATTCAATACTCCCAGCCACCACAGGGTGCATCACGGCTCAAATCCCCAATACATAGATAAAAACTACG
CCGGCGTGCTCATCATTTGGGATCGGCTGTTTGGCACCTTCGTCAAAGAAGAGGAAACCGTGCGCTACGGCATCACCAAG
CCGATTAACAGCATGAACCCGCTCACGGTCACCTTCAGTGAATGGCGCGATATGTTCACAGATGCCACGGCGCCGGGGCT
GAGTCTCGCCGAGCGCTGGCGTCAGCTTTTTGCACCACCCTCCAGCGCCAACGATAAGGATTGA

Upstream 100 bases:

>100_bases
TGCCAAGTGGTAAGTGCACACTGCACCAGGAATAGAAAAGCAAGAACAACAAGTGGCCCACAAGTGTCAGGACTTTTGGG
CACAGACAACAGGGAAGATA

Downstream 100 bases:

>100_bases
GGCTTCGCAAGCTCCATGGCTTGGAGTAAGCTTGGGGCGTCCAAGTCTGAAAGAGAACCCTATGAAACTCTTTGTATTCG
AACATTGTCCCTATTGTGTT

Product: sterol desaturase family protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MNLDKLIAHPELLLIVLAPIFFLCMALEFVVANVRKRLPENARYSKAELLCNLSLAGMHQAADLLSGFLIAKLYLYFFGW
RLFDIEMNGLNFVLLLLAQDFCYYWFHRCSHRCRWMWAAHVAHHSSENMNFSTAFRQSLMYPLAGMWIFWLPLVVIGFDP
AWVVFAVLASLGFQFFVHTQLVDKLGPLEWVFNTPSHHRVHHGSNPQYIDKNYAGVLIIWDRLFGTFVKEEETVRYGITK
PINSMNPLTVTFSEWRDMFTDATAPGLSLAERWRQLFAPPSSANDKD

Sequences:

>Translated_287_residues
MNLDKLIAHPELLLIVLAPIFFLCMALEFVVANVRKRLPENARYSKAELLCNLSLAGMHQAADLLSGFLIAKLYLYFFGW
RLFDIEMNGLNFVLLLLAQDFCYYWFHRCSHRCRWMWAAHVAHHSSENMNFSTAFRQSLMYPLAGMWIFWLPLVVIGFDP
AWVVFAVLASLGFQFFVHTQLVDKLGPLEWVFNTPSHHRVHHGSNPQYIDKNYAGVLIIWDRLFGTFVKEEETVRYGITK
PINSMNPLTVTFSEWRDMFTDATAPGLSLAERWRQLFAPPSSANDKD
>Mature_287_residues
MNLDKLIAHPELLLIVLAPIFFLCMALEFVVANVRKRLPENARYSKAELLCNLSLAGMHQAADLLSGFLIAKLYLYFFGW
RLFDIEMNGLNFVLLLLAQDFCYYWFHRCSHRCRWMWAAHVAHHSSENMNFSTAFRQSLMYPLAGMWIFWLPLVVIGFDP
AWVVFAVLASLGFQFFVHTQLVDKLGPLEWVFNTPSHHRVHHGSNPQYIDKNYAGVLIIWDRLFGTFVKEEETVRYGITK
PINSMNPLTVTFSEWRDMFTDATAPGLSLAERWRQLFAPPSSANDKD

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=237, Percent_Identity=43.0379746835443, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI25144659, Length=215, Percent_Identity=40, Blast_Score=134, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 33243; Mature: 33243

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDKLIAHPELLLIVLAPIFFLCMALEFVVANVRKRLPENARYSKAELLCNLSLAGMHQ
CCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHH
AADLLSGFLIAKLYLYFFGWRLFDIEMNGLNFVLLLLAQDFCYYWFHRCSHRCRWMWAAH
HHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAHHSSENMNFSTAFRQSLMYPLAGMWIFWLPLVVIGFDPAWVVFAVLASLGFQFFVHTQ
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LVDKLGPLEWVFNTPSHHRVHHGSNPQYIDKNYAGVLIIWDRLFGTFVKEEETVRYGITK
HHHHCCCCCEEECCCCCCCCCCCCCCCEECCCCCEEEEEHHHHHHHHHCCCHHHHCCCCC
PINSMNPLTVTFSEWRDMFTDATAPGLSLAERWRQLFAPPSSANDKD
CCCCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNLDKLIAHPELLLIVLAPIFFLCMALEFVVANVRKRLPENARYSKAELLCNLSLAGMHQ
CCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHH
AADLLSGFLIAKLYLYFFGWRLFDIEMNGLNFVLLLLAQDFCYYWFHRCSHRCRWMWAAH
HHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAHHSSENMNFSTAFRQSLMYPLAGMWIFWLPLVVIGFDPAWVVFAVLASLGFQFFVHTQ
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LVDKLGPLEWVFNTPSHHRVHHGSNPQYIDKNYAGVLIIWDRLFGTFVKEEETVRYGITK
HHHHCCCCCEEECCCCCCCCCCCCCCCEECCCCCEEEEEHHHHHHHHHCCCHHHHCCCCC
PINSMNPLTVTFSEWRDMFTDATAPGLSLAERWRQLFAPPSSANDKD
CCCCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]