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The map label for this gene is dinB

Identifier: 119775659

GI number: 119775659

Start: 3036239

End: 3037306

Strand: Reverse

Name: dinB

Synonym: Sama_2527

Alternate gene names: 119775659

Gene position: 3037306-3036239 (Counterclockwise)

Preceding gene: 119775660

Following gene: 119775658

Centisome position: 70.53

GC content: 55.43

Gene sequence:

>1068_bases
ATGCGAAAAATCATTCATATCGATATGGACTGCTATTTTGCGGCCGTCGAGATGCGCGATTTTCCACAATACCGCGGCAA
ACCGCTTGCAGTAGGCGGCAGCAGTGACAGGCGAGGCGTCATCAGCACCTGCAACTATGAGGCCCGAGCCTTTGGTGTAC
GTTCTGCCATGGCTTCGGCCTATGCCCTTAAACTGTGCCCGAATCTGATCCTGGTTCCCGGCCGGATGGAAGTGTACAAG
GCCGTTTCGCAACAAATACGCGAAATCTTCAGTCGTTATACCTCCCTTATTGAGCCTCTGTCGCTGGATGAAGCCTATCT
GGATGTGAGTGACTGCAGCTTGTATCAGGGCTCGGCCACCCGTATTGCCGAGGCGATTCGCAGTGACATATTCAAAGAAA
CCGGCCTGACGGCTTCGGCGGGCGTGAGTCCTATCAAGTTTGTTGCCAAGGTCGCTTCGGATCTTAATAAGCCCAATGGT
CAGTATGTGGTGTCGCCCGATACCCTGATGCACTTCGTCAGAGCCTTGTCCCTGGGGAAGATCCCCGGTGTCGGTAAGGT
CACCGAAGAAAAGCTCAATGCGCTGGGACTTAAAACCTGCGCCGATGTACAGCAGGTGCCGCAGACGCTGCTGACAGAGC
ACTTTGGTAAATTCGGTGCCGTTTTGTATGAGAGGGCACACGGCCGGGATGAGCGGGCCATCGTCTCCCATCGTGAGCGA
AAGTCCGTAGGGGTGGAGACCACACTGCCCAAAGACTTGCATACCCGTGAGGCCTGTCTGGATGTACTTTCATCACTCAT
TCCTGAGCTCAATCGTCGTCTTGGCCGCAGCGCTTCGGGTCGTCGTATTCATAAGCTGGTGGTAAAGCTCAAGTTTGATG
ATTTTCGTCAGACCACCATAGAAAGCCGCGCCGAAGAGCCCTCAGTGAGACTATTCGAATCACTGCTCAGTCAGGCCTTT
GTGCGTGCCGAGGGCAGGGGCATTCGCCTGGTGGGAATTGCGGCGGGCCTGGTTTGTCGGAGCGAGGCCGAACAGGAGGG
CAGCGCCCAGTTGGCGTTAAGCCTTTAG

Upstream 100 bases:

>100_bases
CAGTTCCGGGTGTAAGCCGGGTAAAAAGCGCCTAAGGGCGCTTTTTTATTGCCTGCAATTCTGATACTGTTTTTATATAC
AGTAATAGCAGAGCTTACCC

Downstream 100 bases:

>100_bases
CGATGAATAACGCTGTCTTGATGCGCCTGTGGTTGTGAGTCAGCGCCGGGGCATCTAAAATAGCGCTGTTTCGTGGCCAG
CGGGCCGCGAGTTTAACAGT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MRKIIHIDMDCYFAAVEMRDFPQYRGKPLAVGGSSDRRGVISTCNYEARAFGVRSAMASAYALKLCPNLILVPGRMEVYK
AVSQQIREIFSRYTSLIEPLSLDEAYLDVSDCSLYQGSATRIAEAIRSDIFKETGLTASAGVSPIKFVAKVASDLNKPNG
QYVVSPDTLMHFVRALSLGKIPGVGKVTEEKLNALGLKTCADVQQVPQTLLTEHFGKFGAVLYERAHGRDERAIVSHRER
KSVGVETTLPKDLHTREACLDVLSSLIPELNRRLGRSASGRRIHKLVVKLKFDDFRQTTIESRAEEPSVRLFESLLSQAF
VRAEGRGIRLVGIAAGLVCRSEAEQEGSAQLALSL

Sequences:

>Translated_355_residues
MRKIIHIDMDCYFAAVEMRDFPQYRGKPLAVGGSSDRRGVISTCNYEARAFGVRSAMASAYALKLCPNLILVPGRMEVYK
AVSQQIREIFSRYTSLIEPLSLDEAYLDVSDCSLYQGSATRIAEAIRSDIFKETGLTASAGVSPIKFVAKVASDLNKPNG
QYVVSPDTLMHFVRALSLGKIPGVGKVTEEKLNALGLKTCADVQQVPQTLLTEHFGKFGAVLYERAHGRDERAIVSHRER
KSVGVETTLPKDLHTREACLDVLSSLIPELNRRLGRSASGRRIHKLVVKLKFDDFRQTTIESRAEEPSVRLFESLLSQAF
VRAEGRGIRLVGIAAGLVCRSEAEQEGSAQLALSL
>Mature_355_residues
MRKIIHIDMDCYFAAVEMRDFPQYRGKPLAVGGSSDRRGVISTCNYEARAFGVRSAMASAYALKLCPNLILVPGRMEVYK
AVSQQIREIFSRYTSLIEPLSLDEAYLDVSDCSLYQGSATRIAEAIRSDIFKETGLTASAGVSPIKFVAKVASDLNKPNG
QYVVSPDTLMHFVRALSLGKIPGVGKVTEEKLNALGLKTCADVQQVPQTLLTEHFGKFGAVLYERAHGRDERAIVSHRER
KSVGVETTLPKDLHTREACLDVLSSLIPELNRRLGRSASGRRIHKLVVKLKFDDFRQTTIESRAEEPSVRLFESLLSQAF
VRAEGRGIRLVGIAAGLVCRSEAEQEGSAQLALSL

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI7706681, Length=347, Percent_Identity=31.700288184438, Blast_Score=168, Evalue=8e-42,
Organism=Homo sapiens, GI84043967, Length=346, Percent_Identity=31.7919075144509, Blast_Score=168, Evalue=9e-42,
Organism=Homo sapiens, GI7705344, Length=376, Percent_Identity=31.1170212765957, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI154350220, Length=330, Percent_Identity=27.2727272727273, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI5729982, Length=117, Percent_Identity=41.8803418803419, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1786425, Length=339, Percent_Identity=56.6371681415929, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1787432, Length=223, Percent_Identity=25.1121076233184, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193205700, Length=418, Percent_Identity=30.3827751196172, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI17537959, Length=299, Percent_Identity=27.7591973244147, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193205702, Length=363, Percent_Identity=27.2727272727273, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI115534089, Length=398, Percent_Identity=25.6281407035176, Blast_Score=89, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6324921, Length=207, Percent_Identity=30.9178743961353, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19923006, Length=323, Percent_Identity=29.7213622291022, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21355641, Length=284, Percent_Identity=31.6901408450704, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24644984, Length=284, Percent_Identity=31.6901408450704, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24668444, Length=118, Percent_Identity=38.9830508474576, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO4_SHEAM (A1S8M3)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_928399.1
- ProteinModelPortal:   A1S8M3
- SMR:   A1S8M3
- STRING:   A1S8M3
- GeneID:   4604774
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_2527
- NMPDR:   fig|326297.7.peg.2367
- eggNOG:   COG0389
- HOGENOM:   HBG734504
- OMA:   QAMARQE
- PhylomeDB:   A1S8M3
- ProtClustDB:   PRK02406
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 39120; Mature: 39120

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIHIDMDCYFAAVEMRDFPQYRGKPLAVGGSSDRRGVISTCNYEARAFGVRSAMASA
CCEEEEECCHHHHHHHHHHHCHHHCCCEEEECCCCCCCCCCEECCCHHHHHHHHHHHHHH
YALKLCPNLILVPGRMEVYKAVSQQIREIFSRYTSLIEPLSLDEAYLDVSDCSLYQGSAT
HHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHCCCCCCHHH
RIAEAIRSDIFKETGLTASAGVSPIKFVAKVASDLNKPNGQYVVSPDTLMHFVRALSLGK
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHCC
IPGVGKVTEEKLNALGLKTCADVQQVPQTLLTEHFGKFGAVLYERAHGRDERAIVSHRER
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
KSVGVETTLPKDLHTREACLDVLSSLIPELNRRLGRSASGRRIHKLVVKLKFDDFRQTTI
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHH
ESRAEEPSVRLFESLLSQAFVRAEGRGIRLVGIAAGLVCRSEAEQEGSAQLALSL
HHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MRKIIHIDMDCYFAAVEMRDFPQYRGKPLAVGGSSDRRGVISTCNYEARAFGVRSAMASA
CCEEEEECCHHHHHHHHHHHCHHHCCCEEEECCCCCCCCCCEECCCHHHHHHHHHHHHHH
YALKLCPNLILVPGRMEVYKAVSQQIREIFSRYTSLIEPLSLDEAYLDVSDCSLYQGSAT
HHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHCCCCCCHHH
RIAEAIRSDIFKETGLTASAGVSPIKFVAKVASDLNKPNGQYVVSPDTLMHFVRALSLGK
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHCC
IPGVGKVTEEKLNALGLKTCADVQQVPQTLLTEHFGKFGAVLYERAHGRDERAIVSHRER
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
KSVGVETTLPKDLHTREACLDVLSSLIPELNRRLGRSASGRRIHKLVVKLKFDDFRQTTI
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHH
ESRAEEPSVRLFESLLSQAFVRAEGRGIRLVGIAAGLVCRSEAEQEGSAQLALSL
HHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA