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The map label for this gene is tcpI [H]

Identifier: 119775660

GI number: 119775660

Start: 3037392

End: 3039389

Strand: Reverse

Name: tcpI [H]

Synonym: Sama_2528

Alternate gene names: 119775660

Gene position: 3039389-3037392 (Counterclockwise)

Preceding gene: 119775661

Following gene: 119775659

Centisome position: 70.58

GC content: 55.61

Gene sequence:

>1998_bases
ATGGGACATATCAAACGTTCTTTGAGCCTACAGCTTGTACTGACGCTGGTTGGCGCGCTGGCGATATTGCTGGCGCTGGT
CGCAACCTTTTTGGTCCGTGATGCCAGCCAATCCACCCGCTCTACCATTGATGGCGACATCAATGCGCTGATGGAGCAAA
AAAGCCGCGACATTCGTGGCTACTTTGTTGCTAAGGGCCAAATCATCCATGCAGTGTTTGCCGAACCCGGCCTCGTGGAC
TGGTTTACCCAATACAAGGCCAGGGGCAGCAACCTTGCCAGCGATGCCCAATATCAGCGCATAGTGCAGTACTTCAAATA
TTTTTCCGACAAGGATGCCGATATCAAGTCGGTATTCTTTGGCTCTGCCAATACCTTTGAATATTTCGACCTCAACGGCC
GTTACGATGGCGACCCCAATTACTACACCAACAAGCGCCCCTGGTGGCAGGAAGCTCTCGATAAAGGCGGCCTGTTTGTG
GGCGACCCGGCTGTCGACGCCAATGATGGCTCTATCTCGGCGACGGTAAAAACGCCGGTTTATGGAGCCAACGGCCAGTT
GTTGGGTATTGGCGGCATGGACATTCTTATCGATACCATTGGCAAGTCGCTGCTGGCCCCCATTAAATATCAGGGCTCTG
GCCAGGCGTTTCTGATGACGGGCGATGGCAAGCTGGTGTACTTCCCCGGTTTTAACGAGAGTTTTCCACCTGGCTCAGCC
ATTCAAAAGGTCGACAATAATGGCAGCGAAGGCTTCACTGCCCTTGGCCAATTGATGCAGCGCCAATCCAGTGGTTTTAC
CGATGTGGTCTATCAGGGGAGTCCCCAGCGCGTGGCCTTCGTTGAAGTGGCTGGGGACTACCCCAAACAAAAATGGCACC
TGGCCTTTATGCTTCCCCATGAGGTGATTGAGGCGCCGGTGCGCGATGCCTTCTGGAATGCCTGCCTGATGTCTCTGGGT
ATCATCCTCCTGGTGGGCGTGACAGTGTGGCTGTTGCTGCTCCCGCTTCGCAGGCAGCTCGAGTCGCTCCTCGGTGCCAT
GGACAACATGGCAAGCGGTGAGGGTGATTTGTCCCGCCGTATCGACATTCAGCGGGAAGATGAGCTTGGGCTCATGGCGG
ATGCCTTCAATCGGTTTGCAGCCAAGGTACAACAGATGCTGCGACAGACCCGTGACCTGACCCGCGATGTGGACGACGGC
ATTGTTGAAGCCCGTAAAATTTGTGATGTGGCCGTTGGTGCCGTCTCCAGGCAAAAGGCACAAATCGACTCGGTCGCGGC
CGCCGCTATTGAAATGGCTCACACCAGTCAGGAAATGGCTGCCAGCGCACAGCGGACGGCTGACTTTGCCGAAACTGCCC
AGACACAGGCCGATGACGGCAAACAAATAGTAGCCGAGGCTACTTCTGGCATAGAAACCCTCTCATCCAGAGTGATAGAA
GCCGCAGCAGTGATAAAAGAGCTCAGGGGCAGCTCAGAAAAAATTGGTGAAGTACTCAGCGTTATCCGTAACATTGCCGA
GCAAACCAATCTGCTGGCGCTCAACGCCGCCATTGAAGCCGCCAGAGCCGGGGAGCAGGGGCGGGGTTTTGCCGTGGTGG
CCGATGAGGTGCGCACTCTGGCATCCCGTACGCAGGATTCTACCGCCAACATTCAGGGTATCATCCAGCGCTTGCAACAA
AGTGCCATGGAGGCCGAATCAGTTATGGAGGCAGGTGTGAACGACGCCAAGCGCGGACAATTGCTGACCAGTCAGGTGCA
GGACTCCCTTGGCAAGATCACCGATGCCATTGGCGCAATATTGCAGCAAACCACCGAAATTACTGTGGCCATTGGCCAGC
AGGCGGTGGTGGCCGACGAAGTGGCGCAGAATGTGGAAAATGTGCGCGGACTGTCCGATGATTCCCATTCTGCCAGTCAG
GAATTGGCGGTCAGCCTCAAGGCATTCGAACAGCTCACCCACGCACTGTCCGGTAATATCTCGCAGTTCCGGGTGTAA

Upstream 100 bases:

>100_bases
TTGCCTAAATTTACTCGAATTTTGCTGTTATCCTGCCACTATTGTTGCTAGATTGGTGAGCTATTTCGCCCAACAACAAT
AACTGCGAAAGGGTAATCCA

Downstream 100 bases:

>100_bases
GCCGGGTAAAAAGCGCCTAAGGGCGCTTTTTTATTGCCTGCAATTCTGATACTGTTTTTATATACAGTAATAGCAGAGCT
TACCCATGCGAAAAATCATT

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpI [H]

Number of amino acids: Translated: 665; Mature: 664

Protein sequence:

>665_residues
MGHIKRSLSLQLVLTLVGALAILLALVATFLVRDASQSTRSTIDGDINALMEQKSRDIRGYFVAKGQIIHAVFAEPGLVD
WFTQYKARGSNLASDAQYQRIVQYFKYFSDKDADIKSVFFGSANTFEYFDLNGRYDGDPNYYTNKRPWWQEALDKGGLFV
GDPAVDANDGSISATVKTPVYGANGQLLGIGGMDILIDTIGKSLLAPIKYQGSGQAFLMTGDGKLVYFPGFNESFPPGSA
IQKVDNNGSEGFTALGQLMQRQSSGFTDVVYQGSPQRVAFVEVAGDYPKQKWHLAFMLPHEVIEAPVRDAFWNACLMSLG
IILLVGVTVWLLLLPLRRQLESLLGAMDNMASGEGDLSRRIDIQREDELGLMADAFNRFAAKVQQMLRQTRDLTRDVDDG
IVEARKICDVAVGAVSRQKAQIDSVAAAAIEMAHTSQEMAASAQRTADFAETAQTQADDGKQIVAEATSGIETLSSRVIE
AAAVIKELRGSSEKIGEVLSVIRNIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQDSTANIQGIIQRLQQ
SAMEAESVMEAGVNDAKRGQLLTSQVQDSLGKITDAIGAILQQTTEITVAIGQQAVVADEVAQNVENVRGLSDDSHSASQ
ELAVSLKAFEQLTHALSGNISQFRV

Sequences:

>Translated_665_residues
MGHIKRSLSLQLVLTLVGALAILLALVATFLVRDASQSTRSTIDGDINALMEQKSRDIRGYFVAKGQIIHAVFAEPGLVD
WFTQYKARGSNLASDAQYQRIVQYFKYFSDKDADIKSVFFGSANTFEYFDLNGRYDGDPNYYTNKRPWWQEALDKGGLFV
GDPAVDANDGSISATVKTPVYGANGQLLGIGGMDILIDTIGKSLLAPIKYQGSGQAFLMTGDGKLVYFPGFNESFPPGSA
IQKVDNNGSEGFTALGQLMQRQSSGFTDVVYQGSPQRVAFVEVAGDYPKQKWHLAFMLPHEVIEAPVRDAFWNACLMSLG
IILLVGVTVWLLLLPLRRQLESLLGAMDNMASGEGDLSRRIDIQREDELGLMADAFNRFAAKVQQMLRQTRDLTRDVDDG
IVEARKICDVAVGAVSRQKAQIDSVAAAAIEMAHTSQEMAASAQRTADFAETAQTQADDGKQIVAEATSGIETLSSRVIE
AAAVIKELRGSSEKIGEVLSVIRNIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQDSTANIQGIIQRLQQ
SAMEAESVMEAGVNDAKRGQLLTSQVQDSLGKITDAIGAILQQTTEITVAIGQQAVVADEVAQNVENVRGLSDDSHSASQ
ELAVSLKAFEQLTHALSGNISQFRV
>Mature_664_residues
GHIKRSLSLQLVLTLVGALAILLALVATFLVRDASQSTRSTIDGDINALMEQKSRDIRGYFVAKGQIIHAVFAEPGLVDW
FTQYKARGSNLASDAQYQRIVQYFKYFSDKDADIKSVFFGSANTFEYFDLNGRYDGDPNYYTNKRPWWQEALDKGGLFVG
DPAVDANDGSISATVKTPVYGANGQLLGIGGMDILIDTIGKSLLAPIKYQGSGQAFLMTGDGKLVYFPGFNESFPPGSAI
QKVDNNGSEGFTALGQLMQRQSSGFTDVVYQGSPQRVAFVEVAGDYPKQKWHLAFMLPHEVIEAPVRDAFWNACLMSLGI
ILLVGVTVWLLLLPLRRQLESLLGAMDNMASGEGDLSRRIDIQREDELGLMADAFNRFAAKVQQMLRQTRDLTRDVDDGI
VEARKICDVAVGAVSRQKAQIDSVAAAAIEMAHTSQEMAASAQRTADFAETAQTQADDGKQIVAEATSGIETLSSRVIEA
AAVIKELRGSSEKIGEVLSVIRNIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQDSTANIQGIIQRLQQS
AMEAESVMEAGVNDAKRGQLLTSQVQDSLGKITDAIGAILQQTTEITVAIGQQAVVADEVAQNVENVRGLSDDSHSASQE
LAVSLKAFEQLTHALSGNISQFRV

Specific function: May function as an environmental regulator of TCP biogenesis. Negatively regulates the synthesis of the major pilin subunit of TCP (tcpA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=351, Percent_Identity=27.3504273504274, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1787690, Length=362, Percent_Identity=28.4530386740331, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1788194, Length=416, Percent_Identity=28.3653846153846, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788195, Length=305, Percent_Identity=29.1803278688525, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789453, Length=317, Percent_Identity=29.6529968454259, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 71920; Mature: 71789

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHIKRSLSLQLVLTLVGALAILLALVATFLVRDASQSTRSTIDGDINALMEQKSRDIRG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHCCCCCE
YFVAKGQIIHAVFAEPGLVDWFTQYKARGSNLASDAQYQRIVQYFKYFSDKDADIKSVFF
EEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHEE
GSANTFEYFDLNGRYDGDPNYYTNKRPWWQEALDKGGLFVGDPAVDANDGSISATVKTPV
CCCCCEEEEECCCEECCCCCCCCCCCCHHHHHHHCCCEEECCCCCCCCCCCEEEEEECCE
YGANGQLLGIGGMDILIDTIGKSLLAPIKYQGSGQAFLMTGDGKLVYFPGFNESFPPGSA
ECCCCCEEEECCHHHHHHHHHHHHHCCCEECCCCCEEEEECCCCEEEECCCCCCCCCCHH
IQKVDNNGSEGFTALGQLMQRQSSGFTDVVYQGSPQRVAFVEVAGDYPKQKWHLAFMLPH
HHHHCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCCCEEEEEECCH
EVIEAPVRDAFWNACLMSLGIILLVGVTVWLLLLPLRRQLESLLGAMDNMASGEGDLSRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHC
IDIQREDELGLMADAFNRFAAKVQQMLRQTRDLTRDVDDGIVEARKICDVAVGAVSRQKA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIDSVAAAAIEMAHTSQEMAASAQRTADFAETAQTQADDGKQIVAEATSGIETLSSRVIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AAAVIKELRGSSEKIGEVLSVIRNIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHH
ASRTQDSTANIQGIIQRLQQSAMEAESVMEAGVNDAKRGQLLTSQVQDSLGKITDAIGAI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LQQTTEITVAIGQQAVVADEVAQNVENVRGLSDDSHSASQELAVSLKAFEQLTHALSGNI
HHHHHHEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
SQFRV
HHCCC
>Mature Secondary Structure 
GHIKRSLSLQLVLTLVGALAILLALVATFLVRDASQSTRSTIDGDINALMEQKSRDIRG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHCCCCCE
YFVAKGQIIHAVFAEPGLVDWFTQYKARGSNLASDAQYQRIVQYFKYFSDKDADIKSVFF
EEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHEE
GSANTFEYFDLNGRYDGDPNYYTNKRPWWQEALDKGGLFVGDPAVDANDGSISATVKTPV
CCCCCEEEEECCCEECCCCCCCCCCCCHHHHHHHCCCEEECCCCCCCCCCCEEEEEECCE
YGANGQLLGIGGMDILIDTIGKSLLAPIKYQGSGQAFLMTGDGKLVYFPGFNESFPPGSA
ECCCCCEEEECCHHHHHHHHHHHHHCCCEECCCCCEEEEECCCCEEEECCCCCCCCCCHH
IQKVDNNGSEGFTALGQLMQRQSSGFTDVVYQGSPQRVAFVEVAGDYPKQKWHLAFMLPH
HHHHCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCCCEEEEEECCH
EVIEAPVRDAFWNACLMSLGIILLVGVTVWLLLLPLRRQLESLLGAMDNMASGEGDLSRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHC
IDIQREDELGLMADAFNRFAAKVQQMLRQTRDLTRDVDDGIVEARKICDVAVGAVSRQKA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIDSVAAAAIEMAHTSQEMAASAQRTADFAETAQTQADDGKQIVAEATSGIETLSSRVIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AAAVIKELRGSSEKIGEVLSVIRNIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHH
ASRTQDSTANIQGIIQRLQQSAMEAESVMEAGVNDAKRGQLLTSQVQDSLGKITDAIGAI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LQQTTEITVAIGQQAVVADEVAQNVENVRGLSDDSHSASQELAVSLKAFEQLTHALSGNI
HHHHHHEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
SQFRV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8005659 [H]