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The map label for this gene is ppnK [H]

Identifier: 119775572

GI number: 119775572

Start: 2932197

End: 2933075

Strand: Direct

Name: ppnK [H]

Synonym: Sama_2438

Alternate gene names: 119775572

Gene position: 2932197-2933075 (Clockwise)

Preceding gene: 119775570

Following gene: 119775573

Centisome position: 68.09

GC content: 55.63

Gene sequence:

>879_bases
ATGACATCCCAATTCCACACCATCGGCCTGATCGGCAAACCCCACCACAACGGTACCAACCTGACGCTCAAGCGTTTACA
TCACTGGCTCGGCAGTCAGGGATATGAGGTGCTTGTGGAAGAAAGGGTCGCCGGTGAGCTGGGTGCCAAGGTCGAAGCGG
TCGATTTATTGGCCATAGGCAATCGCTGTGATTTGGCCATTGTGGTGGGTGGCGATGGCAATATGCTGGGCGCTGCCCGG
GTGCTGGCCCGCTTCGATGTGGGCGTGATCGGGGTTAACCGCGGCAATCTGGGATTTCTGACCGACCTGCCACCCGATGG
CTTTGAAGAAAGCCTGGCGGCCGTGCTCGATGGCGAGTTTATCACCGAGCACAGATTTCTGCTTGAAGCGGAAGTACACC
GCCATGGCACCATGAAAGCCAGTAACACCGCCGTCAACGAGGCCGTACTGCACCCGGGCAAAATTGCCCACATGATTGAG
TACGAAGTCTATATCGACAATCAGTTTATGTACTCTCAGCGTGCCGACGGCATGATAGTCTCTACCCCCACAGGCTCTAC
GGCCTACTCGCTGTCAGCGGGCGGCGCCATCTTGACTCCCAACCTTCAGGCGCTGATTTTGGTGCCCATGTTCCCCCATA
CCCTCTCCTGCCGCCCGATAGTGGTGGACGCTAATTCCACCATCAAACTGGTGGTCTCACCGGAAAATGGTGAGAACCTG
GAAGTGAGCTGCGATGGTCACGTCACCCTGGCTGTCTTGCCCGGGGATGAAATTTTTATTCGCCAAAGCAGTGAACGCCT
GCGCCTGATCCATCCCAAAAACTACAATTACTTCCACGTACTGAGAAACAAACTGGGTTGGGGCAGCAAACTTTTCTGA

Upstream 100 bases:

>100_bases
CTCTACTCCAAGCTAAAAATGCTTTGTTTCTGCATACACAGGGCATATTATGGGGATCAATTCTGGCGTTTCAAGGCCTT
GAAGGCGCAGTTTCCGCGAT

Downstream 100 bases:

>100_bases
TTATCCCCTGAAATAAAACCAGTTGAGTTTCAAAACCGAAACTCAACAAGACTTTTACCAGTACAGTCCAACCCTGTAGC
TGTGGCAACGCTCAACCACG

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MTSQFHTIGLIGKPHHNGTNLTLKRLHHWLGSQGYEVLVEERVAGELGAKVEAVDLLAIGNRCDLAIVVGGDGNMLGAAR
VLARFDVGVIGVNRGNLGFLTDLPPDGFEESLAAVLDGEFITEHRFLLEAEVHRHGTMKASNTAVNEAVLHPGKIAHMIE
YEVYIDNQFMYSQRADGMIVSTPTGSTAYSLSAGGAILTPNLQALILVPMFPHTLSCRPIVVDANSTIKLVVSPENGENL
EVSCDGHVTLAVLPGDEIFIRQSSERLRLIHPKNYNYFHVLRNKLGWGSKLF

Sequences:

>Translated_292_residues
MTSQFHTIGLIGKPHHNGTNLTLKRLHHWLGSQGYEVLVEERVAGELGAKVEAVDLLAIGNRCDLAIVVGGDGNMLGAAR
VLARFDVGVIGVNRGNLGFLTDLPPDGFEESLAAVLDGEFITEHRFLLEAEVHRHGTMKASNTAVNEAVLHPGKIAHMIE
YEVYIDNQFMYSQRADGMIVSTPTGSTAYSLSAGGAILTPNLQALILVPMFPHTLSCRPIVVDANSTIKLVVSPENGENL
EVSCDGHVTLAVLPGDEIFIRQSSERLRLIHPKNYNYFHVLRNKLGWGSKLF
>Mature_291_residues
TSQFHTIGLIGKPHHNGTNLTLKRLHHWLGSQGYEVLVEERVAGELGAKVEAVDLLAIGNRCDLAIVVGGDGNMLGAARV
LARFDVGVIGVNRGNLGFLTDLPPDGFEESLAAVLDGEFITEHRFLLEAEVHRHGTMKASNTAVNEAVLHPGKIAHMIEY
EVYIDNQFMYSQRADGMIVSTPTGSTAYSLSAGGAILTPNLQALILVPMFPHTLSCRPIVVDANSTIKLVVSPENGENLE
VSCDGHVTLAVLPGDEIFIRQSSERLRLIHPKNYNYFHVLRNKLGWGSKLF

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=263, Percent_Identity=31.1787072243346, Blast_Score=101, Evalue=9e-22,
Organism=Escherichia coli, GI1788968, Length=293, Percent_Identity=57.3378839590444, Blast_Score=349, Evalue=1e-97,
Organism=Saccharomyces cerevisiae, GI6320794, Length=242, Percent_Identity=29.3388429752066, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322509, Length=240, Percent_Identity=30.8333333333333, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6325068, Length=209, Percent_Identity=32.0574162679426, Blast_Score=112, Evalue=6e-26,
Organism=Drosophila melanogaster, GI28573828, Length=252, Percent_Identity=32.1428571428571, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28573830, Length=252, Percent_Identity=32.1428571428571, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28573826, Length=252, Percent_Identity=32.1428571428571, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI161077047, Length=252, Percent_Identity=32.1428571428571, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28573832, Length=252, Percent_Identity=32.1428571428571, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24653422, Length=277, Percent_Identity=26.7148014440433, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI20129957, Length=277, Percent_Identity=26.7148014440433, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281363321, Length=277, Percent_Identity=26.7148014440433, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281363323, Length=277, Percent_Identity=26.7148014440433, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24653424, Length=277, Percent_Identity=26.7148014440433, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 31824; Mature: 31693

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSQFHTIGLIGKPHHNGTNLTLKRLHHWLGSQGYEVLVEERVAGELGAKVEAVDLLAIG
CCCCEEEEEEEECCCCCCCCEEHHHHHHHHCCCCCEEEEEHHHHHHHCCEEEEEEEEEEC
NRCDLAIVVGGDGNMLGAARVLARFDVGVIGVNRGNLGFLTDLPPDGFEESLAAVLDGEF
CCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHCCCC
ITEHRFLLEAEVHRHGTMKASNTAVNEAVLHPGKIAHMIEYEVYIDNQFMYSQRADGMIV
CCCEEEEEEEEHHHCCCCCCCCCHHHHHHCCCCCEEEEEEEEEEECCEEEECCCCCCEEE
STPTGSTAYSLSAGGAILTPNLQALILVPMFPHTLSCRPIVVDANSTIKLVVSPENGENL
ECCCCCCEEEEECCCEEECCCCEEEEEEECCCCCCCCCEEEEECCCEEEEEECCCCCCEE
EVSCDGHVTLAVLPGDEIFIRQSSERLRLIHPKNYNYFHVLRNKLGWGSKLF
EEEECCEEEEEEECCCEEEEEECCCEEEEECCCCCCEEEEEHHHCCCCCCCC
>Mature Secondary Structure 
TSQFHTIGLIGKPHHNGTNLTLKRLHHWLGSQGYEVLVEERVAGELGAKVEAVDLLAIG
CCCEEEEEEEECCCCCCCCEEHHHHHHHHCCCCCEEEEEHHHHHHHCCEEEEEEEEEEC
NRCDLAIVVGGDGNMLGAARVLARFDVGVIGVNRGNLGFLTDLPPDGFEESLAAVLDGEF
CCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHCCCC
ITEHRFLLEAEVHRHGTMKASNTAVNEAVLHPGKIAHMIEYEVYIDNQFMYSQRADGMIV
CCCEEEEEEEEHHHCCCCCCCCCHHHHHHCCCCCEEEEEEEEEEECCEEEECCCCCCEEE
STPTGSTAYSLSAGGAILTPNLQALILVPMFPHTLSCRPIVVDANSTIKLVVSPENGENL
ECCCCCCEEEEECCCEEECCCCEEEEEEECCCCCCCCCEEEEECCCEEEEEECCCCCCEE
EVSCDGHVTLAVLPGDEIFIRQSSERLRLIHPKNYNYFHVLRNKLGWGSKLF
EEEECCEEEEEEECCCEEEEEECCCEEEEECCCCCCEEEEEHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA