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The map label for this gene is siaT [H]

Identifier: 119775346

GI number: 119775346

Start: 2671808

End: 2673208

Strand: Direct

Name: siaT [H]

Synonym: Sama_2211

Alternate gene names: 119775346

Gene position: 2671808-2673208 (Clockwise)

Preceding gene: 119775345

Following gene: 119775347

Centisome position: 62.05

GC content: 56.89

Gene sequence:

>1401_bases
ATGACCATAGCCACGCTGTTTTTAACCCTGTTCCTGTGCATGCTGCTCGGTATGCCCATCGCCATCGCGCTGGGATTTTC
GAGCATGCTGACCATATTGCTGTTTTCCAACGACTCTCTGGCATCAGTTGCCCTTAAACTCTACGAAGCCACCTCAGAGC
ACTACACCCTGCTGGCGATCCCCTTCTTTATTCTGTCGTCTGCGTTTCTCTCCACCGGTGGCGTGGCACGGCGAATTATC
GATTTTGCCATGGACAGTGTCGGCCACATTCGCGGAGGCCTCGCCATGGCGTCGGTGATGGCTTGTATGCTGTTTGCCGC
GGTATCGGGTTCGTCTCCTGCCACTGTCGCGGCCATTGGATCTATCGTGATTGTGGGCATGGTACGCGCAGGCTACCCGC
AAAAGTTTGCCGCCGGGGTGATTACCACCTCGGGTACACTGGGGATCCTTATTCCTCCCTCAATCGTGATGCTGGTGTAT
GCGGCTGCGACCGAGGTGTCGGCCGCACGTATGTTTATGGCAGGACTCATCCCCGGACTCCTGATGGGTGTGCTGTTGAT
GGTGGCCATTTACATTGTCGCCCGCATTAAAAATCTTCCCTCCCGCCCCTTCCCCGGCGTAAAAGCCCTGTCGCTTTCCA
GCGCCAAGGCCATGGGCGGATTGGCACTGATTTTCATCGTGCTGGGCTCCATTTACGGCGGTGTGGCGAGCCCAACCGAG
GCGGCGGCAGTGGCCTGCGTGTACGCCTATCTGGTCGCGGTGTTTGGCTATCGCGACATAGGCCCACTCAAAGAGGTGCC
ATGGCGCAAAGAAGGTGAAGCCATACTCGCTGCGATAGTTCGCAACCTGCTTCACGTGGGGCTGGGGCTCATCAAGACCC
CCACCGACAAAGAAATCCGCAACGTGGTAAGGGATGGCGCCAAAGTCAGCATCATGCTGCTATTTATCATCGCCAATGCC
ATGCTGTTTGCCCACGTGCTGACCACTGAGCGGATTCCGCACATCATCGCTGAAACCATCGTCGGCTGGGGTCTGCCGCC
CTGGGGCTTCCTGATTATTGTGAACCTGCTGTTGCTGGCGGCCGGAAACTTTATGGAACCTTCAGCCATTCTGCTTATCA
TGGCCCCCATTTTGTTCCCCATCGCCGTGCAGCTCGGTATCGACCCGATTCACCTGGGGATCATCATGGTGGTGAACATG
GAGATCGGTATGTTAACGCCACCGGTGGGGCTGAATTTGTTTGTGACAGCTGGCATCACAGGCCGCAGCATTGGCTGGGT
CATCCATGCGTGCCTGCCTTGGCTGCTGTTGCTGCTGGGCTTCCTGGTACTCATTACCTATGTGCCGCAGATCAGCCTGT
TCCTGCCGGAGTACCTCGACAGCCTGCGAGGGTTTAAATAA

Upstream 100 bases:

>100_bases
CTTCCAACGGTTTCAGCTTCCATGATGAGGCCAAAGAAAGTATGCACCTGGCTGATGAACAGTCCGGCGCCAACGACAAT
AACAATGACGGAGCCAAGTC

Downstream 100 bases:

>100_bases
TCCCTGGCTGCACTGTTGATCCAAAGTGTATTTTAAGCGAGCCTAAGCCATAGATTTACTATGGCTTTTGCCTTTTTGAG
AACCGCCGTACATGCAGATG

Product: C4-dicarboxylate transport protein

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MTIATLFLTLFLCMLLGMPIAIALGFSSMLTILLFSNDSLASVALKLYEATSEHYTLLAIPFFILSSAFLSTGGVARRII
DFAMDSVGHIRGGLAMASVMACMLFAAVSGSSPATVAAIGSIVIVGMVRAGYPQKFAAGVITTSGTLGILIPPSIVMLVY
AAATEVSAARMFMAGLIPGLLMGVLLMVAIYIVARIKNLPSRPFPGVKALSLSSAKAMGGLALIFIVLGSIYGGVASPTE
AAAVACVYAYLVAVFGYRDIGPLKEVPWRKEGEAILAAIVRNLLHVGLGLIKTPTDKEIRNVVRDGAKVSIMLLFIIANA
MLFAHVLTTERIPHIIAETIVGWGLPPWGFLIIVNLLLLAAGNFMEPSAILLIMAPILFPIAVQLGIDPIHLGIIMVVNM
EIGMLTPPVGLNLFVTAGITGRSIGWVIHACLPWLLLLLGFLVLITYVPQISLFLPEYLDSLRGFK

Sequences:

>Translated_466_residues
MTIATLFLTLFLCMLLGMPIAIALGFSSMLTILLFSNDSLASVALKLYEATSEHYTLLAIPFFILSSAFLSTGGVARRII
DFAMDSVGHIRGGLAMASVMACMLFAAVSGSSPATVAAIGSIVIVGMVRAGYPQKFAAGVITTSGTLGILIPPSIVMLVY
AAATEVSAARMFMAGLIPGLLMGVLLMVAIYIVARIKNLPSRPFPGVKALSLSSAKAMGGLALIFIVLGSIYGGVASPTE
AAAVACVYAYLVAVFGYRDIGPLKEVPWRKEGEAILAAIVRNLLHVGLGLIKTPTDKEIRNVVRDGAKVSIMLLFIIANA
MLFAHVLTTERIPHIIAETIVGWGLPPWGFLIIVNLLLLAAGNFMEPSAILLIMAPILFPIAVQLGIDPIHLGIIMVVNM
EIGMLTPPVGLNLFVTAGITGRSIGWVIHACLPWLLLLLGFLVLITYVPQISLFLPEYLDSLRGFK
>Mature_465_residues
TIATLFLTLFLCMLLGMPIAIALGFSSMLTILLFSNDSLASVALKLYEATSEHYTLLAIPFFILSSAFLSTGGVARRIID
FAMDSVGHIRGGLAMASVMACMLFAAVSGSSPATVAAIGSIVIVGMVRAGYPQKFAAGVITTSGTLGILIPPSIVMLVYA
AATEVSAARMFMAGLIPGLLMGVLLMVAIYIVARIKNLPSRPFPGVKALSLSSAKAMGGLALIFIVLGSIYGGVASPTEA
AAVACVYAYLVAVFGYRDIGPLKEVPWRKEGEAILAAIVRNLLHVGLGLIKTPTDKEIRNVVRDGAKVSIMLLFIIANAM
LFAHVLTTERIPHIIAETIVGWGLPPWGFLIIVNLLLLAAGNFMEPSAILLIMAPILFPIAVQLGIDPIHLGIIMVVNME
IGMLTPPVGLNLFVTAGITGRSIGWVIHACLPWLLLLLGFLVLITYVPQISLFLPEYLDSLRGFK

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=428, Percent_Identity=30.1401869158879, Blast_Score=170, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 49390; Mature: 49258

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIATLFLTLFLCMLLGMPIAIALGFSSMLTILLFSNDSLASVALKLYEATSEHYTLLAI
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEHHHH
PFFILSSAFLSTGGVARRIIDFAMDSVGHIRGGLAMASVMACMLFAAVSGSSPATVAAIG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SIVIVGMVRAGYPQKFAAGVITTSGTLGILIPPSIVMLVYAAATEVSAARMFMAGLIPGL
HHHHHHHHHCCCCHHHHCCEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMGVLLMVAIYIVARIKNLPSRPFPGVKALSLSSAKAMGGLALIFIVLGSIYGGVASPTE
HHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
AAAVACVYAYLVAVFGYRDIGPLKEVPWRKEGEAILAAIVRNLLHVGLGLIKTPTDKEIR
HHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
NVVRDGAKVSIMLLFIIANAMLFAHVLTTERIPHIIAETIVGWGLPPWGFLIIVNLLLLA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AGNFMEPSAILLIMAPILFPIAVQLGIDPIHLGIIMVVNMEIGMLTPPVGLNLFVTAGIT
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEEEECCCCCCCCCCCCEEEEEECCC
GRSIGWVIHACLPWLLLLLGFLVLITYVPQISLFLPEYLDSLRGFK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TIATLFLTLFLCMLLGMPIAIALGFSSMLTILLFSNDSLASVALKLYEATSEHYTLLAI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEHHHH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CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]