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The map label for this gene is ahpC [C]

Identifier: 119775229

GI number: 119775229

Start: 2538204

End: 2538809

Strand: Reverse

Name: ahpC [C]

Synonym: Sama_2094

Alternate gene names: 119775229

Gene position: 2538809-2538204 (Counterclockwise)

Preceding gene: 119775231

Following gene: 119775227

Centisome position: 58.96

GC content: 53.47

Gene sequence:

>606_bases
ATGAGCGTATTAGTAGGTCGTAAGGCCCCCGATTTTACTGCTGCTGCCGTTCTGGGTTCAGGCGAAATCGTTGACAACTT
CAACCTGACTGCAGCCATCAAGGGCAAAGCAGCCGTGGTTTTCTTCTACCCACTGGACTTCACTTTCGTGTGCCCATCTG
AGCTGATCGCGTTCGATCACCGCATGGAAGAGTTCACCAAGCGTGGTGTTGAAGTGATCGGTGTGTCCATCGACTCTCAG
TTCAGCCACAACGCCTGGCGTAACACCCCAGTAGACAAGGGTGGTATCGGCCCAGTTAAGTACACTCTGGTGGCTGATGT
TAAGCACGAAATCTGCCAGGCTTACGACGTAGAGCACCCAGAAGCCGGTGTGGCTTTCCGTGGTTCTTTCCTGATTGACA
AGGAAGGTATGGTACGCCACCAGGTAGTGAACGACCTGCCACTGGGCCGTAACGTTGATGAAATGCTGCGTATGATTGAC
GCGCTGCAATTCCACGAAGAGCACGGTGAAGTGTGCCCAGCCGGTTGGGAAAAAGGTAAAAAAGGCATGAGCGCCAGCCC
AGACGGTGTTGCTGCTTACCTGAGCGAGAACGCTGACGATCTGTAA

Upstream 100 bases:

>100_bases
CCAAATTGGGTTGTCAGGCTCATGGCACCTCTTATAATGCTGAATATCTAACAGGAAAGTTCGTATTATCCCTAGCTCAA
TCCATAGATGGAGGTTACCA

Downstream 100 bases:

>100_bases
TCCAATATCCGGATGAGATTGAATCGCATAAAAAGCCGCCCTCGGGCGGCTTTTTTATTTCAGTGATTCGCTTAGGCGCT
TTTGATTTATGCGGCGCTAT

Product: alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MSVLVGRKAPDFTAAAVLGSGEIVDNFNLTAAIKGKAAVVFFYPLDFTFVCPSELIAFDHRMEEFTKRGVEVIGVSIDSQ
FSHNAWRNTPVDKGGIGPVKYTLVADVKHEICQAYDVEHPEAGVAFRGSFLIDKEGMVRHQVVNDLPLGRNVDEMLRMID
ALQFHEEHGEVCPAGWEKGKKGMSASPDGVAAYLSENADDL

Sequences:

>Translated_201_residues
MSVLVGRKAPDFTAAAVLGSGEIVDNFNLTAAIKGKAAVVFFYPLDFTFVCPSELIAFDHRMEEFTKRGVEVIGVSIDSQ
FSHNAWRNTPVDKGGIGPVKYTLVADVKHEICQAYDVEHPEAGVAFRGSFLIDKEGMVRHQVVNDLPLGRNVDEMLRMID
ALQFHEEHGEVCPAGWEKGKKGMSASPDGVAAYLSENADDL
>Mature_200_residues
SVLVGRKAPDFTAAAVLGSGEIVDNFNLTAAIKGKAAVVFFYPLDFTFVCPSELIAFDHRMEEFTKRGVEVIGVSIDSQF
SHNAWRNTPVDKGGIGPVKYTLVADVKHEICQAYDVEHPEAGVAFRGSFLIDKEGMVRHQVVNDLPLGRNVDEMLRMIDA
LQFHEEHGEVCPAGWEKGKKGMSASPDGVAAYLSENADDL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=194, Percent_Identity=50, Blast_Score=202, Evalue=2e-52,
Organism=Homo sapiens, GI4505591, Length=193, Percent_Identity=49.740932642487, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI32455266, Length=193, Percent_Identity=49.740932642487, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI32455264, Length=193, Percent_Identity=49.740932642487, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI5453549, Length=192, Percent_Identity=45.8333333333333, Blast_Score=185, Evalue=2e-47,
Organism=Homo sapiens, GI5802974, Length=196, Percent_Identity=44.3877551020408, Blast_Score=173, Evalue=1e-43,
Organism=Homo sapiens, GI32483377, Length=193, Percent_Identity=44.559585492228, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI33188454, Length=83, Percent_Identity=56.6265060240964, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI4758638, Length=195, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1786822, Length=158, Percent_Identity=37.3417721518987, Blast_Score=116, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI193204376, Length=176, Percent_Identity=50, Blast_Score=178, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI32565831, Length=176, Percent_Identity=50, Blast_Score=177, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17554494, Length=171, Percent_Identity=48.5380116959064, Blast_Score=173, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI25153706, Length=185, Percent_Identity=27.027027027027, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323613, Length=194, Percent_Identity=40.7216494845361, Blast_Score=160, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6320661, Length=179, Percent_Identity=40.7821229050279, Blast_Score=148, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6319407, Length=181, Percent_Identity=29.2817679558011, Blast_Score=85, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24656348, Length=194, Percent_Identity=46.9072164948454, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI17864676, Length=194, Percent_Identity=46.9072164948454, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI17738015, Length=190, Percent_Identity=46.8421052631579, Blast_Score=183, Evalue=7e-47,
Organism=Drosophila melanogaster, GI17157991, Length=192, Percent_Identity=45.3125, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24641739, Length=192, Percent_Identity=45.3125, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI21357347, Length=190, Percent_Identity=44.2105263157895, Blast_Score=170, Evalue=7e-43,
Organism=Drosophila melanogaster, GI24581278, Length=185, Percent_Identity=31.3513513513514, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17975518, Length=191, Percent_Identity=31.413612565445, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24652434, Length=191, Percent_Identity=31.413612565445, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24652436, Length=191, Percent_Identity=31.413612565445, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21970; Mature: 21839

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVGRKAPDFTAAAVLGSGEIVDNFNLTAAIKGKAAVVFFYPLDFTFVCPSELIAFDH
CCEECCCCCCCCEEEEEECCCCEEECCCEEEEECCCEEEEEEEECCEEEECHHHHHHHHH
RMEEFTKRGVEVIGVSIDSQFSHNAWRNTPVDKGGIGPVKYTLVADVKHEICQAYDVEHP
HHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCC
EAGVAFRGSFLIDKEGMVRHQVVNDLPLGRNVDEMLRMIDALQFHEEHGEVCPAGWEKGK
CCCEEEECEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHCC
KGMSASPDGVAAYLSENADDL
CCCCCCCCHHHHEECCCCCCC
>Mature Secondary Structure 
SVLVGRKAPDFTAAAVLGSGEIVDNFNLTAAIKGKAAVVFFYPLDFTFVCPSELIAFDH
CEECCCCCCCCEEEEEECCCCEEECCCEEEEECCCEEEEEEEECCEEEECHHHHHHHHH
RMEEFTKRGVEVIGVSIDSQFSHNAWRNTPVDKGGIGPVKYTLVADVKHEICQAYDVEHP
HHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCC
EAGVAFRGSFLIDKEGMVRHQVVNDLPLGRNVDEMLRMIDALQFHEEHGEVCPAGWEKGK
CCCEEEECEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHCC
KGMSASPDGVAAYLSENADDL
CCCCCCCCHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]