Click here to switch to the map view.

The map label for this gene is kinA [H]

Identifier: 119775217

GI number: 119775217

Start: 2524637

End: 2525947

Strand: Direct

Name: kinA [H]

Synonym: Sama_2082

Alternate gene names: 119775217

Gene position: 2524637-2525947 (Clockwise)

Preceding gene: 119775216

Following gene: 119775228

Centisome position: 58.63

GC content: 51.87

Gene sequence:

>1311_bases
ATGGACTCGATGCTATCCACCATCATTGAAAAGGTTTCCAATACCCGGGGTGAAGCGTTTTTCAACAGCATAACCCTTGC
GCTGCACGATGCCATTGGCGCTGACTTTACCTTCGTTGCCATCCTGGATAAAGAAAACTACAGCTCACATACGCTGGCAC
TGGTGGCAGATGGCAAGCTGGTTGACAACATTTCCTACTCCCTTGCCAATACGCCCTGCGCCAATGCCGCGGATGACTCG
GTGTGCTGTTACCGCGCCGATGTCACTGCCACTTTTCCCGATGATCTGATGCTGCAGGACATGGGAATTGAAGGCTATCT
CGGCACACCGTTGCACAATCTCAAAGGTGAGGTAATGGGGCTCATTGTCGCCCTTTATCGCCGCCCTATTGATAATCACA
GCTGGGCACTGGAGCTATTCAAACTGTTTTCCGGACGAATAGAGGCCGAGCTTGACCGGGTAGAGCACGAAAAAAAGCTC
GAGCAGGCCAATCAATCCCTCGAGACTAAGGTCACTGAACGTACCGAGCACCTGAACCGGGTTATTGCCGACTTAAAGCA
GGCCCAGGATAAACTTGTCGAGTCAGAAAAGATGGGAGCCATGGGCAGCCTGGTGGCGGGTCTTGCCCACGAAGTGAACA
CGCCGCTGGGTGTTGCAATTACAAGTTCCAGCGTAATTAAGGAACACAGGGACCTGCTGGTTAATGCCTATCGCAGCGGG
GATCTGTCCACCGAGCAGCTGGATGAGTTTCTCGATGTCTGTGATAACGCGCTGTCGTTGTTGGATATCAATCTCCATCG
GGCCATCGAACTGGTTGAAAGTTTTAAACGCACGGCGGCGGATCAACACAACAACGATACAGAGCACATTAATCTGGCGC
AGTATTACCATCAGGTCATTACCGCCCTCAAACCACTGCTAAACACCATGCAGGCACAGGTGAAACTTGAAATCCCAACA
GACTGGGAGGTGGATACCGTCCCGGGGGCCCACTCACAGATCCTCACCAATCTGCTCAGTAACAGCATCAGCCATGGCTT
CACTCAGGGCGAGGACAACCAAATCCACATCAGGGGCAAGCGCCTTGCCGATGGCAGTTACCACATCCACTACAGTGACA
ACGGTAAAGGTCTGAACGAAGAAGCCAGAAAACGCATTTTCGAACCCTTTTACACCACGGCGCGCGCCAAAGGCGGCATT
GGTCTTGGGATGAGCATTGTGTTTAACCTTGTTCACCAACAGCTCAATGGAGCCCTGAACTTGCCCGAGTATGATAAAGG
ATTTGCCATGGAATTCAGTTTTAAGGGATAG

Upstream 100 bases:

>100_bases
TAATGCAGGCTTTTTGTTGGCTGTTCAGTCTCTTGCTGGTATGCAAATGGATTCATGGCTATGCTGAATTAATGTCGGCC
GCCGCTACCTGAGAAGCAAC

Downstream 100 bases:

>100_bases
CCGGGAGACGGCATCCAACAAAAAAGGCGAACTATGTTCGCCTTTTACGTTTCTCAGTCTGGGAGCTGAATGCGCTTAGA
GCACATATTTGGCCGAGAAA

Product: Signal transduction histidine kinase regulating C4-dicarboxylate transport system-like protein

Products: NA

Alternate protein names: Stage II sporulation protein F; Stage II sporulation protein J [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MDSMLSTIIEKVSNTRGEAFFNSITLALHDAIGADFTFVAILDKENYSSHTLALVADGKLVDNISYSLANTPCANAADDS
VCCYRADVTATFPDDLMLQDMGIEGYLGTPLHNLKGEVMGLIVALYRRPIDNHSWALELFKLFSGRIEAELDRVEHEKKL
EQANQSLETKVTERTEHLNRVIADLKQAQDKLVESEKMGAMGSLVAGLAHEVNTPLGVAITSSSVIKEHRDLLVNAYRSG
DLSTEQLDEFLDVCDNALSLLDINLHRAIELVESFKRTAADQHNNDTEHINLAQYYHQVITALKPLLNTMQAQVKLEIPT
DWEVDTVPGAHSQILTNLLSNSISHGFTQGEDNQIHIRGKRLADGSYHIHYSDNGKGLNEEARKRIFEPFYTTARAKGGI
GLGMSIVFNLVHQQLNGALNLPEYDKGFAMEFSFKG

Sequences:

>Translated_436_residues
MDSMLSTIIEKVSNTRGEAFFNSITLALHDAIGADFTFVAILDKENYSSHTLALVADGKLVDNISYSLANTPCANAADDS
VCCYRADVTATFPDDLMLQDMGIEGYLGTPLHNLKGEVMGLIVALYRRPIDNHSWALELFKLFSGRIEAELDRVEHEKKL
EQANQSLETKVTERTEHLNRVIADLKQAQDKLVESEKMGAMGSLVAGLAHEVNTPLGVAITSSSVIKEHRDLLVNAYRSG
DLSTEQLDEFLDVCDNALSLLDINLHRAIELVESFKRTAADQHNNDTEHINLAQYYHQVITALKPLLNTMQAQVKLEIPT
DWEVDTVPGAHSQILTNLLSNSISHGFTQGEDNQIHIRGKRLADGSYHIHYSDNGKGLNEEARKRIFEPFYTTARAKGGI
GLGMSIVFNLVHQQLNGALNLPEYDKGFAMEFSFKG
>Mature_436_residues
MDSMLSTIIEKVSNTRGEAFFNSITLALHDAIGADFTFVAILDKENYSSHTLALVADGKLVDNISYSLANTPCANAADDS
VCCYRADVTATFPDDLMLQDMGIEGYLGTPLHNLKGEVMGLIVALYRRPIDNHSWALELFKLFSGRIEAELDRVEHEKKL
EQANQSLETKVTERTEHLNRVIADLKQAQDKLVESEKMGAMGSLVAGLAHEVNTPLGVAITSSSVIKEHRDLLVNAYRSG
DLSTEQLDEFLDVCDNALSLLDINLHRAIELVESFKRTAADQHNNDTEHINLAQYYHQVITALKPLLNTMQAQVKLEIPT
DWEVDTVPGAHSQILTNLLSNSISHGFTQGEDNQIHIRGKRLADGSYHIHYSDNGKGLNEEARKRIFEPFYTTARAKGGI
GLGMSIVFNLVHQQLNGALNLPEYDKGFAMEFSFKG

Specific function: Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. It also autophosphorylates in the presence of ATP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=250, Percent_Identity=23.2, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48343; Mature: 48343

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSMLSTIIEKVSNTRGEAFFNSITLALHDAIGADFTFVAILDKENYSSHTLALVADGKL
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEECCCH
VDNISYSLANTPCANAADDSVCCYRADVTATFPDDLMLQDMGIEGYLGTPLHNLKGEVMG
HHCCHHHHCCCCCCCCCCCCEEEEECCCCEECCCHHHHHHCCCCCCCCCCHHHHHHHHHH
LIVALYRRPIDNHSWALELFKLFSGRIEAELDRVEHEKKLEQANQSLETKVTERTEHLNR
HHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIADLKQAQDKLVESEKMGAMGSLVAGLAHEVNTPLGVAITSSSVIKEHRDLLVNAYRSG
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCC
DLSTEQLDEFLDVCDNALSLLDINLHRAIELVESFKRTAADQHNNDTEHINLAQYYHQVI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHH
TALKPLLNTMQAQVKLEIPTDWEVDTVPGAHSQILTNLLSNSISHGFTQGEDNQIHIRGK
HHHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
RLADGSYHIHYSDNGKGLNEEARKRIFEPFYTTARAKGGIGLGMSIVFNLVHQQLNGALN
EECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
LPEYDKGFAMEFSFKG
CCCCCCCEEEEEECCC
>Mature Secondary Structure
MDSMLSTIIEKVSNTRGEAFFNSITLALHDAIGADFTFVAILDKENYSSHTLALVADGKL
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEECCCH
VDNISYSLANTPCANAADDSVCCYRADVTATFPDDLMLQDMGIEGYLGTPLHNLKGEVMG
HHCCHHHHCCCCCCCCCCCCEEEEECCCCEECCCHHHHHHCCCCCCCCCCHHHHHHHHHH
LIVALYRRPIDNHSWALELFKLFSGRIEAELDRVEHEKKLEQANQSLETKVTERTEHLNR
HHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIADLKQAQDKLVESEKMGAMGSLVAGLAHEVNTPLGVAITSSSVIKEHRDLLVNAYRSG
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCC
DLSTEQLDEFLDVCDNALSLLDINLHRAIELVESFKRTAADQHNNDTEHINLAQYYHQVI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHH
TALKPLLNTMQAQVKLEIPTDWEVDTVPGAHSQILTNLLSNSISHGFTQGEDNQIHIRGK
HHHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
RLADGSYHIHYSDNGKGLNEEARKRIFEPFYTTARAKGGIGLGMSIVFNLVHQQLNGALN
EECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
LPEYDKGFAMEFSFKG
CCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2104615; 2509430; 9384377 [H]