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The map label for this gene is wzb [C]

Identifier: 119775129

GI number: 119775129

Start: 2424820

End: 2425296

Strand: Reverse

Name: wzb [C]

Synonym: Sama_1994

Alternate gene names: 119775129

Gene position: 2425296-2424820 (Counterclockwise)

Preceding gene: 119775130

Following gene: 119775126

Centisome position: 56.32

GC content: 54.51

Gene sequence:

>477_bases
ATGACCAGTACACCCGGTTCGATTCTATTTGTATGCATGGGCAATATCTGCCGTTCTCCCAGCGCCGAAGCAGTGTTTCG
CCAGCGTGCCATCCGCGCAGGACTTGATTTGGTGATTGATTCTGCCGGCACCATTGGCTACCACCAGGGAGAGGCCCCCG
ACGCCCGCTCGGTAAAAGCAGGCGAAGCTCGGGGTTATGATTTCTCTGGGATGCGTGCACGGCAGGTGAAGGACAGCGAT
TTCATGCGTTTTGACCTGATTCTAGCCGCAGACAAGGATAACCTTGCTGAGCTCAAGCGCCGCTGTCCGGCTGAATTCAG
GCATAAGTTACGGCTCATCTTAAGTTTTGGCGAATCGGACATTGAGGAAGTTCCCGACCCATACTACGGCGGGAACGCAG
GGTTTGAGCGTGTGCTCGATCTGCTGGAACACAGCAGTGATGCCTTGATAGCCGCCATTAAGGCGTTGGAAAAATGA

Upstream 100 bases:

>100_bases
AATATCATGGGCTCACTGATAAAGGGCTTCCCAAGGGCGCGCGATTTCTGCGTGTGCGTCCGATGGAATGAATTCCCGCA
GATAAGAGACAAAGACACAA

Downstream 100 bases:

>100_bases
CATTAAAAAAGGGCCATCAGGCCCTTTGGGTTTGAGTACACCTTTTAACGCTGGTCCGGTTTGGCATGGGTGCACAGGCT
AACGCCTCGTTGCTGTGATA

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MTSTPGSILFVCMGNICRSPSAEAVFRQRAIRAGLDLVIDSAGTIGYHQGEAPDARSVKAGEARGYDFSGMRARQVKDSD
FMRFDLILAADKDNLAELKRRCPAEFRHKLRLILSFGESDIEEVPDPYYGGNAGFERVLDLLEHSSDALIAAIKALEK

Sequences:

>Translated_158_residues
MTSTPGSILFVCMGNICRSPSAEAVFRQRAIRAGLDLVIDSAGTIGYHQGEAPDARSVKAGEARGYDFSGMRARQVKDSD
FMRFDLILAADKDNLAELKRRCPAEFRHKLRLILSFGESDIEEVPDPYYGGNAGFERVLDLLEHSSDALIAAIKALEK
>Mature_157_residues
TSTPGSILFVCMGNICRSPSAEAVFRQRAIRAGLDLVIDSAGTIGYHQGEAPDARSVKAGEARGYDFSGMRARQVKDSDF
MRFDLILAADKDNLAELKRRCPAEFRHKLRLILSFGESDIEEVPDPYYGGNAGFERVLDLLEHSSDALIAAIKALEK

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=136, Percent_Identity=38.9705882352941, Blast_Score=96, Evalue=1e-20,
Organism=Homo sapiens, GI4757714, Length=136, Percent_Identity=40.4411764705882, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1788375, Length=151, Percent_Identity=35.0993377483444, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI87081812, Length=141, Percent_Identity=34.0425531914894, Blast_Score=63, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6325330, Length=153, Percent_Identity=32.6797385620915, Blast_Score=90, Evalue=2e-19,
Organism=Drosophila melanogaster, GI78706770, Length=140, Percent_Identity=40.7142857142857, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI78706772, Length=140, Percent_Identity=40.7142857142857, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI78706766, Length=133, Percent_Identity=36.8421052631579, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI78706768, Length=133, Percent_Identity=36.8421052631579, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI78706764, Length=125, Percent_Identity=36, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI78711846, Length=146, Percent_Identity=33.5616438356164, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17367; Mature: 17236

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTPGSILFVCMGNICRSPSAEAVFRQRAIRAGLDLVIDSAGTIGYHQGEAPDARSVKA
CCCCCCHHHHEEHHHHHCCCCHHHHHHHHHHHHCHHHEEECCCCCCCCCCCCCCCCCCCC
GEARGYDFSGMRARQVKDSDFMRFDLILAADKDNLAELKRRCPAEFRHKLRLILSFGESD
CCCCCCCCCCCCHHHCCCCCCEEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHCCCHH
IEEVPDPYYGGNAGFERVLDLLEHSSDALIAAIKALEK
HHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TSTPGSILFVCMGNICRSPSAEAVFRQRAIRAGLDLVIDSAGTIGYHQGEAPDARSVKA
CCCCCHHHHEEHHHHHCCCCHHHHHHHHHHHHCHHHEEECCCCCCCCCCCCCCCCCCCC
GEARGYDFSGMRARQVKDSDFMRFDLILAADKDNLAELKRRCPAEFRHKLRLILSFGESD
CCCCCCCCCCCCHHHCCCCCCEEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHCCCHH
IEEVPDPYYGGNAGFERVLDLLEHSSDALIAAIKALEK
HHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]