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The map label for this gene is aspC [H]

Identifier: 119774940

GI number: 119774940

Start: 2196597

End: 2197790

Strand: Reverse

Name: aspC [H]

Synonym: Sama_1805

Alternate gene names: 119774940

Gene position: 2197790-2196597 (Counterclockwise)

Preceding gene: 119774941

Following gene: 119774938

Centisome position: 51.04

GC content: 51.42

Gene sequence:

>1194_bases
ATGATATTTTCCCAGGTTGTACCCGCACCCGCCGATCCGATTTTAGGTCTGACCGATGCCTTCAAGGCTGATCCCAGGAC
CGATAAAGTCAATCTTGGGGTTGGGATCTATAAAGACGAAGCAGGGCAGACCCCGGTACTAAAGTCGGTGAAGCAAGCTG
AAGCCATCCTGCTCGCTGAAGAGAACACCAAAAACTATCTGGGGATTGAGGGCGTAACCTTGTATAACAAGGTTGTCCAG
GAGCTGCTCTTTGGTGCAACCCACACAGTCACCAACCAAGAACGGGCGGTGACAGCACAGGCTCCGGGTGGTACCGGCGC
GCTGCGTGTTGCGGCAGAGTTTGTGGTACGAAACACACCAAGCCGGGTGATCTGGGTGAGTAATCCAACCTGGGCGAACC
ATCAAAACATTTTTGAAACGGCAGGCCTCACCACAAAAGAATACGGATACTATGATGCAGCCAACCATGACATCGACTTT
GATGCCATGCTGAGGTCACTCGAAGCAGCCAATCAGGGAGATCTGGTGTTATTACACGGCTGCTGTCACAACCCAACCGG
AATTGATTTGACGCTCGAGCAATGGCAAAAGGTGGGCGAGCTTTGTGCAGCCAAAGGTCTGGTTCCACTGTTTGATTTTG
CCTATCAGGGCTTTGGGCGTGGTATAGAAGAAGACGCGGAAGGTCTGCGTTTGGTCGCATCCATGGTGCCAGAACTGATT
ATTGCCAATTCTTTCTCCAAAAACTTTGGTCTCTACAACGAGCGCATTGGTGCAGTGACTCTGGTTGCTGCAACGGCAGA
GGAAGCCAAGGTGGCATTCAGTCAGGTCAAACGTACCATTCGTGCCAATTATTCGAATCCACCGGCTCACGGTGCACTGA
TTGTGAGTACGATTTTAAGTCGCCCGGAACTGAAAGCGGCATGGGAGCAAGAATTGGCAGAAATGCGCGAACGTATTGCC
GAAATGCGTACTTTGTTCGTTGAGAGTCTCGCAGCAGCCGGTGTAACACAGGACTTTTCATTTATCAGCCGTCAGATGGG
GATGTTCAGCTTCTCTGGACTGAATAAGGCGCAGGTGGAAGCCCTCAGAGCTGAACATGGTGTGTACATTGTGGGTTCAG
GCAGAATAAGCGTTGCCGGCATGACCAAAACCAATATGCCGGTTATTTGCAGCGCGATTGCAGCAGTGCTCTGA

Upstream 100 bases:

>100_bases
AAGATTTTCATCGAGAATCTTTAGCCAGCGCTACATTACGATTAGCAGCAATGCTATAAATATGCGGTTTTCATTACTTC
CATTCTAAAGGATAGATCCC

Downstream 100 bases:

>100_bases
TTTTACAAAACAAATTGATGTGAAAAAAAAGGCTGCCAGGTGCAGCCTTTTTTAATCAAACCCCTCTCGTCGCTAGGCTA
TCAAACGTTTGCGACCCACA

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MIFSQVVPAPADPILGLTDAFKADPRTDKVNLGVGIYKDEAGQTPVLKSVKQAEAILLAEENTKNYLGIEGVTLYNKVVQ
ELLFGATHTVTNQERAVTAQAPGGTGALRVAAEFVVRNTPSRVIWVSNPTWANHQNIFETAGLTTKEYGYYDAANHDIDF
DAMLRSLEAANQGDLVLLHGCCHNPTGIDLTLEQWQKVGELCAAKGLVPLFDFAYQGFGRGIEEDAEGLRLVASMVPELI
IANSFSKNFGLYNERIGAVTLVAATAEEAKVAFSQVKRTIRANYSNPPAHGALIVSTILSRPELKAAWEQELAEMRERIA
EMRTLFVESLAAAGVTQDFSFISRQMGMFSFSGLNKAQVEALRAEHGVYIVGSGRISVAGMTKTNMPVICSAIAAVL

Sequences:

>Translated_397_residues
MIFSQVVPAPADPILGLTDAFKADPRTDKVNLGVGIYKDEAGQTPVLKSVKQAEAILLAEENTKNYLGIEGVTLYNKVVQ
ELLFGATHTVTNQERAVTAQAPGGTGALRVAAEFVVRNTPSRVIWVSNPTWANHQNIFETAGLTTKEYGYYDAANHDIDF
DAMLRSLEAANQGDLVLLHGCCHNPTGIDLTLEQWQKVGELCAAKGLVPLFDFAYQGFGRGIEEDAEGLRLVASMVPELI
IANSFSKNFGLYNERIGAVTLVAATAEEAKVAFSQVKRTIRANYSNPPAHGALIVSTILSRPELKAAWEQELAEMRERIA
EMRTLFVESLAAAGVTQDFSFISRQMGMFSFSGLNKAQVEALRAEHGVYIVGSGRISVAGMTKTNMPVICSAIAAVL
>Mature_397_residues
MIFSQVVPAPADPILGLTDAFKADPRTDKVNLGVGIYKDEAGQTPVLKSVKQAEAILLAEENTKNYLGIEGVTLYNKVVQ
ELLFGATHTVTNQERAVTAQAPGGTGALRVAAEFVVRNTPSRVIWVSNPTWANHQNIFETAGLTTKEYGYYDAANHDIDF
DAMLRSLEAANQGDLVLLHGCCHNPTGIDLTLEQWQKVGELCAAKGLVPLFDFAYQGFGRGIEEDAEGLRLVASMVPELI
IANSFSKNFGLYNERIGAVTLVAATAEEAKVAFSQVKRTIRANYSNPPAHGALIVSTILSRPELKAAWEQELAEMRERIA
EMRTLFVESLAAAGVTQDFSFISRQMGMFSFSGLNKAQVEALRAEHGVYIVGSGRISVAGMTKTNMPVICSAIAAVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=396, Percent_Identity=41.9191919191919, Blast_Score=313, Evalue=2e-85,
Organism=Homo sapiens, GI4504067, Length=401, Percent_Identity=39.9002493765586, Blast_Score=291, Evalue=6e-79,
Organism=Homo sapiens, GI117414139, Length=381, Percent_Identity=27.2965879265092, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=62.6262626262626, Blast_Score=532, Evalue=1e-152,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=45.088161209068, Blast_Score=360, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI71981858, Length=395, Percent_Identity=41.5189873417722, Blast_Score=335, Evalue=2e-92,
Organism=Caenorhabditis elegans, GI25147133, Length=395, Percent_Identity=42.0253164556962, Blast_Score=330, Evalue=9e-91,
Organism=Caenorhabditis elegans, GI17569539, Length=369, Percent_Identity=40.1084010840108, Blast_Score=283, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17569537, Length=387, Percent_Identity=29.7157622739018, Blast_Score=184, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI25147136, Length=211, Percent_Identity=40.2843601895735, Blast_Score=177, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=34.6007604562738, Blast_Score=164, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6323055, Length=405, Percent_Identity=36.5432098765432, Blast_Score=291, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6322743, Length=430, Percent_Identity=34.4186046511628, Blast_Score=241, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24580972, Length=397, Percent_Identity=41.5617128463476, Blast_Score=316, Evalue=2e-86,
Organism=Drosophila melanogaster, GI24580970, Length=397, Percent_Identity=41.5617128463476, Blast_Score=315, Evalue=2e-86,
Organism=Drosophila melanogaster, GI24654046, Length=399, Percent_Identity=41.6040100250627, Blast_Score=312, Evalue=2e-85,
Organism=Drosophila melanogaster, GI19922362, Length=399, Percent_Identity=41.6040100250627, Blast_Score=312, Evalue=3e-85,
Organism=Drosophila melanogaster, GI19920542, Length=390, Percent_Identity=41.5384615384615, Blast_Score=311, Evalue=6e-85,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42939; Mature: 42939

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFSQVVPAPADPILGLTDAFKADPRTDKVNLGVGIYKDEAGQTPVLKSVKQAEAILLAE
CCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEECEEEEECCCCCCHHHHHHHHHHEEEEEE
ENTKNYLGIEGVTLYNKVVQELLFGATHTVTNQERAVTAQAPGGTGALRVAAEFVVRNTP
CCCCCEECCCCHHHHHHHHHHHHHCCHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCC
SRVIWVSNPTWANHQNIFETAGLTTKEYGYYDAANHDIDFDAMLRSLEAANQGDLVLLHG
CEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEC
CCHNPTGIDLTLEQWQKVGELCAAKGLVPLFDFAYQGFGRGIEEDAEGLRLVASMVPELI
CCCCCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IANSFSKNFGLYNERIGAVTLVAATAEEAKVAFSQVKRTIRANYSNPPAHGALIVSTILS
HHCCCCCCCCCHHHCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHC
RPELKAAWEQELAEMRERIAEMRTLFVESLAAAGVTQDFSFISRQMGMFSFSGLNKAQVE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHH
ALRAEHGVYIVGSGRISVAGMTKTNMPVICSAIAAVL
HHHHCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MIFSQVVPAPADPILGLTDAFKADPRTDKVNLGVGIYKDEAGQTPVLKSVKQAEAILLAE
CCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEECEEEEECCCCCCHHHHHHHHHHEEEEEE
ENTKNYLGIEGVTLYNKVVQELLFGATHTVTNQERAVTAQAPGGTGALRVAAEFVVRNTP
CCCCCEECCCCHHHHHHHHHHHHHCCHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCC
SRVIWVSNPTWANHQNIFETAGLTTKEYGYYDAANHDIDFDAMLRSLEAANQGDLVLLHG
CEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEC
CCHNPTGIDLTLEQWQKVGELCAAKGLVPLFDFAYQGFGRGIEEDAEGLRLVASMVPELI
CCCCCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IANSFSKNFGLYNERIGAVTLVAATAEEAKVAFSQVKRTIRANYSNPPAHGALIVSTILS
HHCCCCCCCCCHHHCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHC
RPELKAAWEQELAEMRERIAEMRTLFVESLAAAGVTQDFSFISRQMGMFSFSGLNKAQVE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHH
ALRAEHGVYIVGSGRISVAGMTKTNMPVICSAIAAVL
HHHHCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]